ATE111954T1 - Verfahren zur transformation von menschlichen b- lymphocyten. - Google Patents

Verfahren zur transformation von menschlichen b- lymphocyten.

Info

Publication number
ATE111954T1
ATE111954T1 AT90902005T AT90902005T ATE111954T1 AT E111954 T1 ATE111954 T1 AT E111954T1 AT 90902005 T AT90902005 T AT 90902005T AT 90902005 T AT90902005 T AT 90902005T AT E111954 T1 ATE111954 T1 AT E111954T1
Authority
AT
Austria
Prior art keywords
cells
lymphocytes
methods
transforming
human
Prior art date
Application number
AT90902005T
Other languages
English (en)
Inventor
Riccardo Dalla-Favera
Stephanie Seremitis
Original Assignee
Univ New York
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ New York filed Critical Univ New York
Application granted granted Critical
Publication of ATE111954T1 publication Critical patent/ATE111954T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C12N5/12—Fused cells, e.g. hybridomas
    • C12N5/16—Animal cells
    • C12N5/163—Animal cells one of the fusion partners being a B or a T lymphocyte
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • C12N2510/02—Cells for production
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • C12N2510/04—Immortalised cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)
AT90902005T 1988-12-19 1989-12-15 Verfahren zur transformation von menschlichen b- lymphocyten. ATE111954T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28668088A 1988-12-19 1988-12-19
US34093989A 1989-04-20 1989-04-20

Publications (1)

Publication Number Publication Date
ATE111954T1 true ATE111954T1 (de) 1994-10-15

Family

ID=26964003

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90902005T ATE111954T1 (de) 1988-12-19 1989-12-15 Verfahren zur transformation von menschlichen b- lymphocyten.

Country Status (6)

Country Link
EP (1) EP0404925B1 (de)
JP (1) JPH03503960A (de)
AT (1) ATE111954T1 (de)
CA (1) CA2005744A1 (de)
DE (1) DE68918440T2 (de)
WO (1) WO1990006994A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2398783A (en) 2003-02-26 2004-09-01 Antonio Lanzavecchia A method for producing immortalised human B memory lymphocytes
WO2004092220A1 (en) * 2003-04-14 2004-10-28 Board Of Regents, The University Of Texas System Methods for ex vivo hybridoma-free production of polyclonal and monoclonal antibodies and generation of immortalized cell populations
JPWO2007060864A1 (ja) * 2005-11-24 2009-05-07 国立大学法人 奈良先端科学技術大学院大学 増殖と分化の制御可能な抗体産生前駆ｂ細胞

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4652522A (en) * 1983-07-05 1987-03-24 The University Of Pennsylvania Continuous lymphocyte cell lines, their production and use
US4804627A (en) * 1985-05-09 1989-02-14 Sloan-Kettering Institute For Cancer Research Method for cloning lymphoblastoid cells

Also Published As

Publication number Publication date
EP0404925A4 (en) 1992-07-08
DE68918440D1 (de) 1994-10-27
EP0404925A1 (de) 1991-01-02
JPH03503960A (ja) 1991-09-05
EP0404925B1 (de) 1994-09-21
CA2005744A1 (en) 1990-06-19
WO1990006994A1 (en) 1990-06-28
DE68918440T2 (de) 1995-01-19

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties