ATE112675T1 - Granulare zubereitungen und verfahren zur ihrer herstellung. - Google Patents

Granulare zubereitungen und verfahren zur ihrer herstellung.

Info

Publication number
ATE112675T1
ATE112675T1 AT91303569T AT91303569T ATE112675T1 AT E112675 T1 ATE112675 T1 AT E112675T1 AT 91303569 T AT91303569 T AT 91303569T AT 91303569 T AT91303569 T AT 91303569T AT E112675 T1 ATE112675 T1 AT E112675T1
Authority
AT
Austria
Prior art keywords
fatty acid
acid ester
polyglycerol fatty
active ingredient
pharmacologically active
Prior art date
Application number
AT91303569T
Other languages
English (en)
Inventor
Minoru Yoshioka
Toshio Kashihara
Hidetoshi Horibe
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Application granted granted Critical
Publication of ATE112675T1 publication Critical patent/ATE112675T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K40/00Shaping or working-up of animal feeding-stuffs
    • A23K40/10Shaping or working-up of animal feeding-stuffs by agglomeration; by granulation, e.g. making powders
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B01J2/30Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic using agents to prevent the granules sticking together; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23PSHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
    • A23P10/00Shaping or working of foodstuffs characterised by the products
    • A23P10/20Agglomerating; Granulating; Tabletting
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1617Organic compounds, e.g. phospholipids, fats
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1617Organic compounds, e.g. phospholipids, fats
    • A61K9/1623Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1652Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Glanulating (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Fats And Perfumes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT91303569T 1990-04-28 1991-04-22 Granulare zubereitungen und verfahren zur ihrer herstellung. ATE112675T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP11438290 1990-04-28

Publications (1)

Publication Number Publication Date
ATE112675T1 true ATE112675T1 (de) 1994-10-15

Family

ID=14636279

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91303569T ATE112675T1 (de) 1990-04-28 1991-04-22 Granulare zubereitungen und verfahren zur ihrer herstellung.

Country Status (10)

Country Link
US (1) US5443846A (de)
EP (1) EP0455391B1 (de)
JP (1) JP3124063B2 (de)
KR (1) KR0171218B1 (de)
AT (1) ATE112675T1 (de)
CA (1) CA2041378C (de)
DE (2) DE69104539T4 (de)
DK (1) DK0455391T3 (de)
ES (1) ES2061179T3 (de)
IE (1) IE65045B1 (de)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW209174B (de) * 1991-04-19 1993-07-11 Takeda Pharm Industry Co Ltd
JPH07112940A (ja) * 1993-08-26 1995-05-02 Takeda Chem Ind Ltd 徐放性非経口投与製剤およびその製造方法
KR100354702B1 (ko) * 1993-11-23 2002-12-28 유로-셀티크 소시에떼 아노뉨 약학조성물의제조방법및서방형조성물
US5891471A (en) * 1993-11-23 1999-04-06 Euro-Celtique, S.A. Pharmaceutical multiparticulates
US5843480A (en) * 1994-03-14 1998-12-01 Euro-Celtique, S.A. Controlled release diamorphine formulation
GB9422154D0 (en) 1994-11-03 1994-12-21 Euro Celtique Sa Pharmaceutical compositions and method of producing the same
US5965161A (en) 1994-11-04 1999-10-12 Euro-Celtique, S.A. Extruded multi-particulates
SE511313C2 (sv) 1997-01-13 1999-09-06 Gs Dev Ab Komposition med reglerad frisättning innefattande fettsyraester av diacylglycerol
EP0988858A1 (de) * 1997-04-18 2000-03-29 Taisho Pharmaceutical Co., Ltd Mikroemulsion
US5891476A (en) * 1997-12-22 1999-04-06 Reo; Joe P. Tastemasked pharmaceutical system
US20020029520A1 (en) * 1998-05-21 2002-03-14 Weder Donald E. Decorative attachments and methods of use
DE19918325A1 (de) 1999-04-22 2000-10-26 Euro Celtique Sa Verfahren zur Herstellung von Arzneiformen mit regulierter Wirkstofffreisetzung mittels Extrusion
JP4974419B2 (ja) * 2001-06-12 2012-07-11 東和薬品株式会社 薬物含有徐放性顆粒およびそれを含む錠剤
SE0200154D0 (sv) * 2002-01-21 2002-01-21 Galenica Ab New process
US20050031686A1 (en) * 2002-03-25 2005-02-10 Truffini & Regge' Farmaceutici Srl Gastroresistant tablets for alimentary, dietetic and therapeutic use
ES2295647T3 (es) 2002-07-15 2008-04-16 Alcon, Inc. Composiciones de implante farmaceuticas lipofilas, no polimeras, para uso intraocular.
CN1812793A (zh) * 2003-06-27 2006-08-02 大塚制药株式会社 药物持续释放颗粒及其制备方法
US20070059358A1 (en) * 2003-07-02 2007-03-15 Tianjin Tasly Pharmaceutical Co., Ltd., China Matrix adjuvants and the drop pills prepared with them
US7364755B2 (en) * 2003-07-07 2008-04-29 Synthon Ip Inc. Modified calcium phosphate excipient
DE102004049241A1 (de) * 2004-10-09 2006-04-20 Sanofi-Aventis Deutschland Gmbh Trockner und Verfahren zum Steuern eines Trockners
US20060275228A1 (en) * 2005-05-09 2006-12-07 Bissett Donald L Skin care compositions containing idebenone
ZA200711123B (en) 2005-06-27 2009-08-26 Biovail Lab Int Srl Modified-release formulations of a bupropion salt
WO2007022092A1 (en) * 2005-08-15 2007-02-22 Stepan Company High melt lipids
KR101034411B1 (ko) * 2006-04-17 2011-05-12 메이지 세이카 가부시키가이샤 유청 단백질-함유 과립 및 그의 제조방법
WO2008053920A1 (en) * 2006-10-31 2008-05-08 Kaneka Corporation Physiologically active substance-containing granular composition and method of producing the same
US20090246276A1 (en) 2008-01-28 2009-10-01 Graham Jackson Pharmaceutical Compositions
US8287902B2 (en) * 2008-07-23 2012-10-16 Rainbow Medical Ltd. Enhanced-diffusion capsule
JP5230308B2 (ja) * 2008-09-04 2013-07-10 協友アグリ株式会社 溶出が制御された農薬製剤
KR101159890B1 (ko) * 2008-12-22 2012-06-25 주식회사 삼양웰푸드 분말 유지 조성물
US8227399B2 (en) * 2010-02-12 2012-07-24 Evonik Goldschmidt Gmbh Polyglycerol esters and their use
JP5650956B2 (ja) * 2010-08-31 2015-01-07 株式会社ファンケル 混合顆粒剤の製造方法
US9353301B2 (en) 2013-11-25 2016-05-31 Ecolab Usa Inc. Composition for dust control
JP6178233B2 (ja) * 2013-12-25 2017-08-09 三井化学アグロ株式会社 徐放性農薬製剤及びその製造方法
US9492396B2 (en) 2014-07-15 2016-11-15 Yossi Gross Enhanced drug delivery pill
WO2019087084A1 (en) 2017-11-02 2019-05-09 Eman Biodiscoveries Sd. Bhd. Extract of orthosiphon stamineus, formulations, and uses thereof
US10675248B2 (en) 2018-08-14 2020-06-09 Alma Therapeutics Ltd. Expandable pill
WO2025032355A1 (de) * 2023-08-04 2025-02-13 Ioi Oleo Gmbh Grundlage für suppositorien oder ovula sowie darauf basierende suppositorien- oder ovulamasse und deren verwendung in einem herstellungsverfahren
WO2025134761A1 (ja) * 2023-12-21 2025-06-26 アサヒグループ食品株式会社 錠菓の製造方法及び錠菓の舌触りの滑らかさの向上方法

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH574245A5 (de) * 1971-06-04 1976-04-15 Boehringer Mannheim Gmbh
US3936391A (en) * 1971-06-16 1976-02-03 Drackett Company Hydrated polyglycerol ester composition
DE2143519B2 (de) * 1971-08-31 1974-05-30 Sandoz Ag, 8500 Nuernberg Verfahren zur Wirbelschichtgranulation pulverförmiger pharmazeutischer Mischungen
JPS4856577A (de) * 1971-11-22 1973-08-08
DE2426812A1 (de) * 1974-06-04 1976-01-02 Klinge Co Chem Pharm Fab Verfahren zur herstellung von granulaten
US4386120A (en) * 1980-01-07 1983-05-31 Nippon Kayaku Kabushiki Kaisha Process for producing polyacrylic acid salt granules easily soluble in water
JPS56140915A (en) * 1980-04-07 1981-11-04 Yamanouchi Pharmaceut Co Ltd Pharmaceutical preparation for solid drug
DE3224619A1 (de) * 1981-07-14 1983-05-19 Freund Industrial Co., Ltd., Tokyo Orale pharmazeutische zusammensetzung
JPS58214333A (ja) * 1982-06-04 1983-12-13 Dai Ichi Seiyaku Co Ltd 粒状物
JPS5944327A (ja) * 1982-09-06 1984-03-12 Taiyo Kagaku Kk L−アスコルビン酸およびその塩類の安定化法
US4904478A (en) * 1983-08-11 1990-02-27 Mission Pharmacal Company Slow-release sodium fluoride tablet and method for treatment of osteoporosis
US4894233A (en) * 1984-10-05 1990-01-16 Sharma Shri C Novel drug delivery system for decongestants
US4755387A (en) * 1985-03-21 1988-07-05 The Procter & Gamble Company Therapeutic particles
US4820523A (en) * 1986-04-15 1989-04-11 Warner-Lambert Company Pharmaceutical composition
DE3702029A1 (de) * 1987-01-24 1988-08-04 Basf Ag Waessriges oder pulverfoermiges, wasserdispergierbares praeparat eines in wasser schwerloeslichen pharmazeutischen wirkstoffs und verfahren zu seiner herstellung
JP2547995B2 (ja) * 1987-01-26 1996-10-30 昭和電工株式会社 反すう動物用粒剤及びその製造法
DE3721721C1 (de) * 1987-07-01 1988-06-09 Hoechst Ag Verfahren zur Umhuellung von Granulaten
DE3837628A1 (de) * 1988-11-05 1990-05-10 Broesamle Peter Verfahren und vorrichtung zur behandlung von organischen schlaemmen
AU645003B2 (en) * 1988-11-08 1994-01-06 Takeda Chemical Industries Ltd. Sustained release preparations
CA1331713C (en) * 1988-12-29 1994-08-30 Hitoshi Iijima Granular composition for ruminant
US5017383A (en) * 1989-08-22 1991-05-21 Taisho Pharmaceutical Co., Ltd. Method of producing fine coated pharmaceutical preparation
US5169645A (en) * 1989-10-31 1992-12-08 Duquesne University Of The Holy Ghost Directly compressible granules having improved flow properties

Also Published As

Publication number Publication date
CA2041378A1 (en) 1991-10-29
JP3124063B2 (ja) 2001-01-15
KR0171218B1 (ko) 1999-01-15
IE911276A1 (en) 1991-11-06
DE69104539T4 (de) 1995-07-27
EP0455391A3 (de) 1991-12-18
IE65045B1 (en) 1995-10-04
EP0455391B1 (de) 1994-10-12
DE69104539T2 (de) 1995-03-23
EP0455391A2 (de) 1991-11-06
ES2061179T3 (es) 1994-12-01
CA2041378C (en) 2002-02-12
JPH05237A (ja) 1993-01-08
DE69104539D1 (de) 1994-11-17
US5443846A (en) 1995-08-22
DK0455391T3 (da) 1995-03-13
KR910018069A (ko) 1991-11-30

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee