ATE113026T1 - Jodpropargylmonoester von dicarbonsäureanhydriden und ihre anwendung als antimikrobenmittel. - Google Patents
Jodpropargylmonoester von dicarbonsäureanhydriden und ihre anwendung als antimikrobenmittel.Info
- Publication number
- ATE113026T1 ATE113026T1 AT89308820T AT89308820T ATE113026T1 AT E113026 T1 ATE113026 T1 AT E113026T1 AT 89308820 T AT89308820 T AT 89308820T AT 89308820 T AT89308820 T AT 89308820T AT E113026 T1 ATE113026 T1 AT E113026T1
- Authority
- AT
- Austria
- Prior art keywords
- cycloalkenyl
- cycloalkyl
- alkenyl
- alkyl
- aryl
- Prior art date
Links
- 150000008064 anhydrides Chemical class 0.000 title abstract 2
- 239000004599 antimicrobial Substances 0.000 title 1
- 125000003118 aryl group Chemical group 0.000 abstract 7
- 125000000392 cycloalkenyl group Chemical group 0.000 abstract 7
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 7
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 6
- 125000003342 alkenyl group Chemical group 0.000 abstract 6
- 125000000217 alkyl group Chemical group 0.000 abstract 6
- -1 amino, carboxyl Chemical group 0.000 abstract 5
- 229930194542 Keto Natural products 0.000 abstract 4
- 125000003545 alkoxy group Chemical group 0.000 abstract 4
- 125000005843 halogen group Chemical group 0.000 abstract 4
- 125000000623 heterocyclic group Chemical group 0.000 abstract 4
- 239000001257 hydrogen Substances 0.000 abstract 4
- 229910052739 hydrogen Inorganic materials 0.000 abstract 4
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 4
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 4
- 125000000468 ketone group Chemical group 0.000 abstract 4
- 229910052760 oxygen Inorganic materials 0.000 abstract 4
- 239000001301 oxygen Substances 0.000 abstract 4
- MYMOFIZGZYHOMD-UHFFFAOYSA-N Dioxygen Chemical compound O=O MYMOFIZGZYHOMD-UHFFFAOYSA-N 0.000 abstract 3
- 239000000203 mixture Substances 0.000 abstract 3
- 229910052757 nitrogen Inorganic materials 0.000 abstract 3
- 229910052717 sulfur Inorganic materials 0.000 abstract 3
- 125000004434 sulfur atom Chemical group 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 2
- 230000003641 microbiacidal effect Effects 0.000 abstract 2
- 238000006467 substitution reaction Methods 0.000 abstract 2
- PAVNZLVXYJDFNR-UHFFFAOYSA-N 3,3-dimethyloxane-2,6-dione Chemical compound CC1(C)CCC(=O)OC1=O PAVNZLVXYJDFNR-UHFFFAOYSA-N 0.000 abstract 1
- GCQOAXGCHJTEBR-UHFFFAOYSA-N 4-(3-iodoprop-2-ynoxy)-4-oxobutanoic acid Chemical class OC(=O)CCC(=O)OCC#CI GCQOAXGCHJTEBR-UHFFFAOYSA-N 0.000 abstract 1
- POLIXZIAIMAECK-UHFFFAOYSA-N 4-[2-(2,6-dioxomorpholin-4-yl)ethyl]morpholine-2,6-dione Chemical compound C1C(=O)OC(=O)CN1CCN1CC(=O)OC(=O)C1 POLIXZIAIMAECK-UHFFFAOYSA-N 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 150000001768 cations Chemical class 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- LVHBHZANLOWSRM-UHFFFAOYSA-N itaconic acid Chemical class OC(=O)CC(=C)C(O)=O LVHBHZANLOWSRM-UHFFFAOYSA-N 0.000 abstract 1
- 150000002688 maleic acid derivatives Chemical class 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 125000005498 phthalate group Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/20—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
- C07C279/24—Y being a hetero atom
- C07C279/26—X and Y being nitrogen atoms, i.e. biguanides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/08—Preparation of carboxylic acid esters by reacting carboxylic acids or symmetrical anhydrides with the hydroxy or O-metal group of organic compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/62—Halogen-containing esters
- C07C69/63—Halogen-containing esters of saturated acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/62—Halogen-containing esters
- C07C69/65—Halogen-containing esters of unsaturated acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/62—Halogen-containing esters
- C07C69/65—Halogen-containing esters of unsaturated acids
- C07C69/657—Maleic acid esters; Fumaric acid esters; Halomaleic acid esters; Halofumaric acid esters
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/67—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of saturated acids
- C07C69/708—Ethers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/76—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/76—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
- C07C69/80—Phthalic acid esters
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Cosmetics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US24406088A | 1988-09-14 | 1988-09-14 | |
| US07/311,523 US5073570A (en) | 1988-09-14 | 1989-02-16 | Mono-iodopropargyl esters of dicarboxylic anhydrides and their use as antimicrobial agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE113026T1 true ATE113026T1 (de) | 1994-11-15 |
Family
ID=26936297
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT89308820T ATE113026T1 (de) | 1988-09-14 | 1989-08-31 | Jodpropargylmonoester von dicarbonsäureanhydriden und ihre anwendung als antimikrobenmittel. |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US5073570A (de) |
| EP (1) | EP0359442B1 (de) |
| JP (1) | JPH0725720B2 (de) |
| AT (1) | ATE113026T1 (de) |
| CA (1) | CA1334977C (de) |
| DE (1) | DE68918910T2 (de) |
| ES (1) | ES2062021T3 (de) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5209930A (en) * | 1990-12-10 | 1993-05-11 | Rohm And Haas Company | Preparation and use of n-iodopropargyl oxycarbonyl amino acid esters and derivatives as antimicrobial agents |
| US6143204A (en) * | 1998-06-19 | 2000-11-07 | Lonza Inc. | Stabilization of iodopropynl compounds |
| ATE322361T1 (de) | 1999-05-24 | 2006-04-15 | Lonza Ag | Isothiazolone/amine oxide holzschutzmittel |
| MXPA01012014A (es) | 1999-05-24 | 2003-09-04 | Lonza Ag | Conservadores de madera de cobre/oxido de amina. |
| ATE289902T1 (de) | 1999-05-24 | 2005-03-15 | Lonza Ag | Azol/amin oxid holzschutzmittel und fungizide |
| NZ516197A (en) | 1999-05-24 | 2004-05-28 | Lonza Ag | Amine oxide/iodine containing blends for wood preservation |
| AU7492701A (en) | 2000-05-24 | 2001-12-03 | Lonza Ag | Amine oxide wood preservatives |
| WO2002001958A2 (en) | 2000-06-30 | 2002-01-10 | Lonza Inc. | Compositions comprising a boron compound and an amine oxide |
| WO2002067685A1 (en) * | 2001-02-26 | 2002-09-06 | Lonza Inc. | Stable preservative formulations comprising halopropynyl compounds and butoxydiglycol solvent |
| TWI318100B (en) | 2001-03-01 | 2009-12-11 | Lonza Ag | Preservative blends containing quaternary ammonium compounds |
| CA2439640A1 (en) | 2001-03-01 | 2002-09-12 | Lonza Inc. | Combination of an iodopropynyl derivative with a ketone acid or its salt and/or with an aromatic carboxylic acid or its salt |
| AU2002322720B2 (en) | 2001-07-25 | 2008-11-13 | Raptor Pharmaceutical Inc. | Compositions and methods for modulating blood-brain barrier transport |
| ITMI20040244A1 (it) * | 2004-02-13 | 2004-05-13 | Vama Farmacosmetica S R L | Sostanza batteriostatica per preparati ad uso topico in particolare per uso dermofarmaceutico e cosmetico e preparati comprendenti questa sostanza |
| CN102379684B (zh) | 2005-04-28 | 2014-11-19 | 普罗透斯数字保健公司 | 药物信息系统 |
| KR20090071598A (ko) | 2006-09-18 | 2009-07-01 | 랩터 파마슈티컬 인코포레이티드 | 수용체 결합 단백질(ｒａｐ)-접합체 투여에 의한 간 질환의 치료 |
| EP2398500B1 (de) | 2009-02-20 | 2019-03-13 | 2-BBB Medicines B.V. | Arzneiabgabesystem auf glutathion-basis |
| ES2942923T3 (es) | 2009-05-06 | 2023-06-07 | Laboratory Skin Care Inc | Composiciones de administración dérmica que comprenden complejos de agente activo-partículas de fosfato de calcio y métodos de uso de las mismas |
| US20120077778A1 (en) | 2010-09-29 | 2012-03-29 | Andrea Bourdelais | Ladder-Frame Polyether Conjugates |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3823183A (en) * | 1968-12-19 | 1974-07-09 | Alelio G D | Unsaturated ester of halogenated alkenes |
| US3796746A (en) * | 1968-12-19 | 1974-03-12 | Alelio G D | Unsaturated ester of halogenated alkenes |
| US3793293A (en) * | 1971-08-04 | 1974-02-19 | Nat Starch Chem Corp | Electrophotographic coating compositions having bromine-containing polymer binders |
| US4107122A (en) * | 1975-12-22 | 1978-08-15 | Monsanto Company | Copolymer plasticizers comprising novel ω-bromoalkyl esters of acyclic unsaturated dicarboxylic acids |
| US4259350A (en) * | 1978-03-15 | 1981-03-31 | Sankyo Company Limited | Iodopropargyl derivatives, their use and preparation |
| DE3227220A1 (de) * | 1982-07-21 | 1984-02-02 | Bayer Ag, 5090 Leverkusen | Jodpropargylcarbonsaeureester |
-
1989
- 1989-02-16 US US07/311,523 patent/US5073570A/en not_active Expired - Fee Related
- 1989-08-31 ES ES89308820T patent/ES2062021T3/es not_active Expired - Lifetime
- 1989-08-31 DE DE68918910T patent/DE68918910T2/de not_active Expired - Fee Related
- 1989-08-31 EP EP89308820A patent/EP0359442B1/de not_active Expired - Lifetime
- 1989-08-31 AT AT89308820T patent/ATE113026T1/de not_active IP Right Cessation
- 1989-09-13 JP JP1235883A patent/JPH0725720B2/ja not_active Expired - Lifetime
- 1989-09-14 CA CA000611489A patent/CA1334977C/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP0359442A2 (de) | 1990-03-21 |
| CA1334977C (en) | 1995-03-28 |
| DE68918910D1 (de) | 1994-11-24 |
| ES2062021T3 (es) | 1994-12-16 |
| JPH02180848A (ja) | 1990-07-13 |
| DE68918910T2 (de) | 1995-03-16 |
| JPH0725720B2 (ja) | 1995-03-22 |
| EP0359442B1 (de) | 1994-10-19 |
| US5073570A (en) | 1991-12-17 |
| EP0359442A3 (de) | 1992-01-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |