ATE113591T1 - 4-benzyl-5-phenyl-2,4-dihydro-3h-1,2,4-triazol- - one und ihre verwendung als antikonvulsiva. - Google Patents
4-benzyl-5-phenyl-2,4-dihydro-3h-1,2,4-triazol- - one und ihre verwendung als antikonvulsiva.Info
- Publication number
- ATE113591T1 ATE113591T1 AT90124971T AT90124971T ATE113591T1 AT E113591 T1 ATE113591 T1 AT E113591T1 AT 90124971 T AT90124971 T AT 90124971T AT 90124971 T AT90124971 T AT 90124971T AT E113591 T1 ATE113591 T1 AT E113591T1
- Authority
- AT
- Austria
- Prior art keywords
- anticonvulsants
- dihydro
- benzyl
- phenyl
- triazole
- Prior art date
Links
- 229940125681 anticonvulsant agent Drugs 0.000 title abstract 2
- 239000001961 anticonvulsive agent Substances 0.000 title abstract 2
- DWTQVIVNXACHOV-UHFFFAOYSA-N 4-benzyl-3-phenyl-1h-1,2,4-triazol-5-one Chemical compound C=1C=CC=CC=1CN1C(=O)NN=C1C1=CC=CC=C1 DWTQVIVNXACHOV-UHFFFAOYSA-N 0.000 title 1
- 206010015037 epilepsy Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D249/12—Oxygen or sulfur atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/453,440 US4966909A (en) | 1989-12-20 | 1989-12-20 | 4-benzyl-5-phenyl-2,4-dihydro-3H-1,2,4-triazol-3-ones and their use as anticonvulsants |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE113591T1 true ATE113591T1 (de) | 1994-11-15 |
Family
ID=23800598
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT90124971T ATE113591T1 (de) | 1989-12-20 | 1990-12-20 | 4-benzyl-5-phenyl-2,4-dihydro-3h-1,2,4-triazol- - one und ihre verwendung als antikonvulsiva. |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US4966909A (de) |
| EP (1) | EP0435177B1 (de) |
| JP (1) | JP2968053B2 (de) |
| KR (1) | KR0154529B1 (de) |
| AT (1) | ATE113591T1 (de) |
| AU (1) | AU634003B2 (de) |
| DE (1) | DE69013871T2 (de) |
| DK (1) | DK0435177T3 (de) |
| ES (1) | ES2066096T3 (de) |
| IE (1) | IE64989B1 (de) |
| PH (1) | PH27352A (de) |
| ZA (1) | ZA9010080B (de) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4966909A (en) * | 1989-12-20 | 1990-10-30 | Merrell Dow Pharmaceuticals | 4-benzyl-5-phenyl-2,4-dihydro-3H-1,2,4-triazol-3-ones and their use as anticonvulsants |
| SE470120B (sv) * | 1992-04-03 | 1993-11-08 | Whirlpool Int | Förfarande för styrning av mikrovågsenergin i en mikrovågsugn och mikrovågsugn för genomförande av förfarandet |
| AU704798B2 (en) * | 1995-04-20 | 1999-05-06 | Hoechst Marion Roussel, Inc. | 3-phenyl-1,4-dialkyl-1,2,4-triazolium salts and their use as antidepressants |
| TW467902B (en) | 1996-07-31 | 2001-12-11 | Bristol Myers Squibb Co | Diphenyl heterocycles as potassium channel modulators |
| US6489487B1 (en) * | 1998-08-03 | 2002-12-03 | Sumitomo Chemical Company, Limited | Triazolone derivatives, use thereof, and intermediates therefor |
| US6156775A (en) * | 1999-03-01 | 2000-12-05 | Novartis Ag | Use of fluorinated triazoles in treating affective and attention disorders |
| TW200505441A (en) | 2003-03-24 | 2005-02-16 | Hoffmann La Roche | Non-nucleoside reverse transcriptase inhibitorsⅠ |
| US7400548B2 (en) * | 2005-02-09 | 2008-07-15 | International Business Machines Corporation | Method for providing multiple reads/writes using a 2read/2write register file array |
| MX2009009920A (es) | 2007-03-29 | 2009-10-19 | Hoffmann La Roche | Inhibidores no nucleosidos de transcriptasa inversa. |
| JP7698989B2 (ja) | 2021-06-10 | 2025-06-26 | Ｔｍｔマシナリー株式会社 | 紡糸引取装置 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1126882B (de) * | 1960-05-03 | 1962-04-05 | Boehringer Sohn Ingelheim | Verfahren zur Herstellung von 1,2,4-Triazolonen-(5) |
| BE621842A (de) * | 1962-08-27 | |||
| GB1068083A (en) * | 1964-04-02 | 1967-05-10 | Philippe Gold Aubert | í¸-1,2,4-triazolone-(5) derivatives |
| US3621099A (en) * | 1969-03-05 | 1971-11-16 | Charles R Jacobson | Therapeutic compositions and methods for stimulating the central nervous system |
| EP0036711B1 (de) * | 1980-03-22 | 1985-12-04 | Fbc Limited | Heterocyclische pestizide Verbindungen, Verfahren zu ihrer Herstellung, sie enthaltende Zusammensetzungen und ihre Verwendung |
| DD153953A3 (de) * | 1980-04-01 | 1982-02-17 | Gottfried Schuster | Mittel zur chemotherapie von virosen der kulturpflanzen |
| DD160447A1 (de) * | 1981-03-26 | 1983-08-03 | Johannes Dost | Herbizide mittel, die 1,2,4-triazolinone-(5) enthalten |
| BE894856A (fr) * | 1982-10-28 | 1983-02-14 | Fahlberg List Veb | Compositions herbicides a base d'un derive de la 1,2,4-triazolinone-(5) |
| JP2593084B2 (ja) * | 1986-12-19 | 1997-03-19 | メレルダウファーマスーティカルズ インコーポレーテッド | ５−アリールー３ｈ−１，２，４−トリアゾールー３−オン類の神経変性障害の処置への用途 |
| PH24094A (en) * | 1986-12-19 | 1990-03-05 | Merrell Dow Pharma | 5-aryl-3h-1,2,4-triazol-3-ones and their use as anticonvulsants |
| US4966909A (en) * | 1989-12-20 | 1990-10-30 | Merrell Dow Pharmaceuticals | 4-benzyl-5-phenyl-2,4-dihydro-3H-1,2,4-triazol-3-ones and their use as anticonvulsants |
-
1989
- 1989-12-20 US US07/453,440 patent/US4966909A/en not_active Expired - Fee Related
-
1990
- 1990-12-14 ZA ZA9010080A patent/ZA9010080B/xx unknown
- 1990-12-14 AU AU68081/90A patent/AU634003B2/en not_active Ceased
- 1990-12-19 KR KR1019900021073A patent/KR0154529B1/ko not_active Expired - Fee Related
- 1990-12-19 JP JP2411704A patent/JP2968053B2/ja not_active Expired - Fee Related
- 1990-12-19 IE IE459990A patent/IE64989B1/en not_active IP Right Cessation
- 1990-12-20 PH PH41759A patent/PH27352A/en unknown
- 1990-12-20 DK DK90124971.4T patent/DK0435177T3/da active
- 1990-12-20 ES ES90124971T patent/ES2066096T3/es not_active Expired - Lifetime
- 1990-12-20 EP EP90124971A patent/EP0435177B1/de not_active Expired - Lifetime
- 1990-12-20 DE DE69013871T patent/DE69013871T2/de not_active Expired - Fee Related
- 1990-12-20 AT AT90124971T patent/ATE113591T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| JPH04128271A (ja) | 1992-04-28 |
| JP2968053B2 (ja) | 1999-10-25 |
| EP0435177B1 (de) | 1994-11-02 |
| IE64989B1 (en) | 1995-09-20 |
| AU634003B2 (en) | 1993-02-11 |
| EP0435177A3 (en) | 1992-01-08 |
| IE904599A1 (en) | 1991-07-03 |
| DK0435177T3 (da) | 1994-11-21 |
| US4966909A (en) | 1990-10-30 |
| PH27352A (en) | 1993-06-21 |
| ZA9010080B (en) | 1991-10-30 |
| KR0154529B1 (ko) | 1998-11-16 |
| ES2066096T3 (es) | 1995-03-01 |
| EP0435177A2 (de) | 1991-07-03 |
| DE69013871T2 (de) | 1995-03-09 |
| AU6808190A (en) | 1991-06-27 |
| DE69013871D1 (de) | 1994-12-08 |
| KR910011807A (ko) | 1991-08-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| REN | Ceased due to non-payment of the annual fee |