ATE113942T1 - Lipoxygenase inhibierende hydroxamsäure und n- hydroxyharnstoff-derivate. - Google Patents

Lipoxygenase inhibierende hydroxamsäure und n- hydroxyharnstoff-derivate.

Info

Publication number
ATE113942T1
ATE113942T1 AT92903377T AT92903377T ATE113942T1 AT E113942 T1 ATE113942 T1 AT E113942T1 AT 92903377 T AT92903377 T AT 92903377T AT 92903377 T AT92903377 T AT 92903377T AT E113942 T1 ATE113942 T1 AT E113942T1
Authority
AT
Austria
Prior art keywords
hydrogen
hydroxamic acid
hydroxyurea derivatives
alkenyl
sulfur
Prior art date
Application number
AT92903377T
Other languages
English (en)
Inventor
Rodney William Stevens
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Application granted granted Critical
Publication of ATE113942T1 publication Critical patent/ATE113942T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D307/10—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/14—Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D307/18—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/22—Nitrogen atoms not forming part of a nitro radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Furan Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Lubricants (AREA)
AT92903377T 1991-02-07 1992-01-08 Lipoxygenase inhibierende hydroxamsäure und n- hydroxyharnstoff-derivate. ATE113942T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP3016325A JPH0730061B2 (ja) 1991-02-07 1991-02-07 ヒドロキサム酸誘導体および組成物

Publications (1)

Publication Number Publication Date
ATE113942T1 true ATE113942T1 (de) 1994-11-15

Family

ID=11913313

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92903377T ATE113942T1 (de) 1991-02-07 1992-01-08 Lipoxygenase inhibierende hydroxamsäure und n- hydroxyharnstoff-derivate.

Country Status (21)

Country Link
EP (1) EP0570401B1 (de)
JP (1) JPH0730061B2 (de)
KR (1) KR930703279A (de)
AT (1) ATE113942T1 (de)
AU (1) AU648872B2 (de)
CA (1) CA2101539A1 (de)
DE (1) DE69200665T2 (de)
DK (1) DK0570401T3 (de)
ES (1) ES2063578T3 (de)
FI (1) FI933492L (de)
HU (1) HUT65539A (de)
IE (1) IE920392A1 (de)
IL (1) IL100846A0 (de)
MX (1) MX9200519A (de)
MY (1) MY134478A (de)
NO (1) NO932815L (de)
NZ (1) NZ241530A (de)
PT (1) PT100093A (de)
TW (1) TW222627B (de)
WO (1) WO1992013848A1 (de)
ZA (1) ZA92862B (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5639782A (en) * 1992-03-04 1997-06-17 Center For Innovative Technology Neolignan derivatives as platelet activating factor receptor antagonists and 5-lipoxygenase inhibitors
US5463083A (en) 1992-07-13 1995-10-31 Cytomed, Inc. Compounds and methods for the treatment of cardiovascular, inflammatory and immune disorders
US5434151A (en) * 1992-08-24 1995-07-18 Cytomed, Inc. Compounds and methods for the treatment of disorders mediated by platelet activating factor or products of 5-lipoxygenase
HUT72601A (en) 1992-07-13 1996-05-28 Cytomed Inc 2,5-diaryl tetrahydro-thiophenes-furans and analogs for the treatment of inflammatory and immune disorders
US5750565A (en) 1995-05-25 1998-05-12 Cytomed, Inc. Compounds and methods for the treatment of cardiovascular, inflammatory and immune disorders
US5792776A (en) * 1994-06-27 1998-08-11 Cytomed, Inc., Compounds and methods for the treatment of cardiovascular, inflammatory and immune disorders
EE9600184A (et) * 1994-06-27 1997-06-16 Cytomed, Inc. Kardiovaskulaar-, inflammatoor- ja immuunhaiguste raviühendid ja -meetodid
US6201016B1 (en) * 1994-06-27 2001-03-13 Cytomed Incorporated Compounds and methods for the treatment of cardiovascular, inflammatory and immune disorders
US5703093A (en) * 1995-05-31 1997-12-30 Cytomed, Inc. Compounds and methods for the treatment of cardiovascular, inflammatory and immune disorders
MX9701042A (es) * 1996-02-07 1998-05-31 Pfizer Compuestos del acido hidroxamico.

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1044308A (en) * 1964-04-28 1966-09-28 Langbein Pfanhauser Werke Ag Electrodeposition of bright copper
US3393209A (en) * 1965-10-04 1968-07-16 Dow Chemical Co Furfuryl and tetrahydrofurfuryl phenyl ureas
JPS5742632B2 (de) * 1972-12-25 1982-09-09
DE3882732T2 (de) * 1987-02-10 1993-12-02 Abbott Lab Indol, Benzofuran, Benzothiophen enthaltende, Lipoxygenase hemmende Verbindungen.
GB2201008B (en) * 1987-02-12 1991-10-23 Stc Plc Optical fibre cables

Also Published As

Publication number Publication date
ES2063578T3 (es) 1995-01-01
DE69200665D1 (de) 1994-12-15
KR930703279A (ko) 1993-11-29
WO1992013848A1 (en) 1992-08-20
NO932815D0 (no) 1993-08-06
EP0570401A1 (de) 1993-11-24
ZA92862B (en) 1993-08-06
FI933492A7 (fi) 1993-08-06
JPH0730061B2 (ja) 1995-04-05
NO932815L (no) 1993-08-09
TW222627B (de) 1994-04-21
CA2101539A1 (en) 1992-08-08
AU1173692A (en) 1992-09-07
JPH04257571A (ja) 1992-09-11
PT100093A (pt) 1993-03-31
FI933492A0 (fi) 1993-08-06
IE920392A1 (en) 1992-08-12
IL100846A0 (en) 1992-11-15
MY134478A (en) 2007-12-31
HU9302283D0 (en) 1993-10-28
NZ241530A (en) 1994-06-27
HUT65539A (en) 1994-06-28
FI933492L (fi) 1993-08-06
EP0570401B1 (de) 1994-11-09
MX9200519A (es) 1992-08-31
AU648872B2 (en) 1994-05-05
DE69200665T2 (de) 1995-04-06
DK0570401T3 (da) 1994-12-05

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee