ATE113961T1 - Therapeutische peptide. - Google Patents

Therapeutische peptide.

Info

Publication number: ATE113961T1
Authority: AT; Austria
Prior art keywords: naturally occurring; peptide; bombesin; analog; peptide bond
Prior art date: 1987-09-24

Application number

AT88308916T

Other languages

English (en)

Inventor

David H Coy

Jacques-Pierre Moreau

Original Assignee

Univ Tulane

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-09-24

Filing date

1988-09-26

Publication date

1994-11-15

1988-09-26 Application filed by Univ Tulane filed Critical Univ Tulane

1994-11-15 Application granted granted Critical

1994-11-15 Publication of ATE113961T1 publication Critical patent/ATE113961T1/de

Links

108090000765 processed proteins & peptides Proteins 0.000 title abstract 4
102000004196 processed proteins & peptides Human genes 0.000 title 1
230000001225 therapeutic effect Effects 0.000 title 1
108010051479 Bombesin Proteins 0.000 abstract 4
102000013585 Bombesin Human genes 0.000 abstract 4
DNDCVAGJPBKION-DOPDSADYSA-N bombesin Chemical compound C([C@@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(N)=O)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](CC=1NC2=CC=CC=C2C=1)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H]1NC(=O)CC1)C(C)C)C1=CN=CN1 DNDCVAGJPBKION-DOPDSADYSA-N 0.000 abstract 4
238000001727 in vivo Methods 0.000 abstract 2
125000003275 alpha amino acid group Chemical group 0.000 abstract 1
150000001413 amino acids Chemical class 0.000 abstract 1
230000004071 biological effect Effects 0.000 abstract 1
238000003776 cleavage reaction Methods 0.000 abstract 1
230000002860 competitive effect Effects 0.000 abstract 1
230000000694 effects Effects 0.000 abstract 1
239000003112 inhibitor Substances 0.000 abstract 1
230000007017 scission Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
- C07K7/086—Bombesin; Related peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/02—Linear peptides containing at least one abnormal peptide link
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Biophysics (AREA)
General Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Pharmacology & Pharmacy (AREA)
Genetics & Genomics (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

AT88308916T 1987-09-24 1988-09-26 Therapeutische peptide. ATE113961T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US10057187A	1987-09-24	1987-09-24

Publications (1)

Publication Number	Publication Date
ATE113961T1 true ATE113961T1 (de)	1994-11-15

Family

ID=22280431

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT88308916T ATE113961T1 (de)	1987-09-24	1988-09-26	Therapeutische peptide.

Country Status (9)

Country	Link
EP (1)	EP0309297B1 (de)
JP (1)	JP2795449B2 (de)
AT (1)	ATE113961T1 (de)
DE (1)	DE3852086T2 (de)
DK (1)	DK249489A (de)
ES (1)	ES2065336T3 (de)
FI (1)	FI100719B (de)
NO (1)	NO178306C (de)
WO (1)	WO1989002897A1 (de)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5877277A (en) *	1987-09-24	1999-03-02	Biomeasure, Inc.	Octapeptide bombesin analogs
US5084555A (en) *	1989-08-21	1992-01-28	The Administrators Of The Tulane Educational Fund	An octapeptide bombesin analog
AU618029B2 (en) *	1987-11-02	1991-12-12	Imperial Chemical Industries Plc	Polypeptide compounds
GB8808768D0 (en) *	1988-04-14	1988-05-18	Erba Carlo Spa	Peptide ligands for bombesin receptors
GB8813356D0 (en) *	1988-06-06	1988-07-13	Ici Plc	Polypeptide compounds
GB2231051B (en) *	1989-05-05	1992-12-16	Erba Carlo Spa	Bombesin antagonists
IE903958A1 (en) *	1989-11-06	1991-05-08	Erba Carlo Spa	Reduced irreversible bombesin antagonists
NZ236114A (en) *	1989-11-22	1993-04-28	Merrell Dow Pharma	Peptide antagonists of bombesin and of gastrin releasing peptide, and pharmaceutical compositions
US5834433A (en) *	1990-07-26	1998-11-10	Merrell Pharmaceuticals Inc.	Compounds and pharmaceutical uses of peptides of bombesin and GRP
AU641789B2 (en) *	1990-07-26	1993-09-30	Aventisub Ii Inc.	Peptides
US5244883A (en) *	1990-11-29	1993-09-14	The Administrators Of The Tulane Educational Fund	Nonapeptide bombesin antagonists
US5369094A (en) *	1990-11-29	1994-11-29	The Administrators Of The Tulane Educational Fund	Polypeptide bombesin antagonists
WO1992020707A1 (en) *	1991-05-23	1992-11-26	Merrell Dow Pharmaceuticals Inc.	Bombesin analogs
WO1993016105A1 (en) *	1992-02-07	1993-08-19	Merrell Dow Pharmaceuticals Inc.	Phenylalanine analogs of bombesin
US6492330B1 (en)	1996-08-16	2002-12-10	National Institute Of Immunology	Antiangiogenic drugs
US6156725A (en) *	1996-08-16	2000-12-05	National Institute Of Immunology	Drug for the treatment of cancer
EP0835662B1 (de) *	1996-10-08	2001-11-14	National Institute of Immunology	Arzneimittel zur Behandlung von Krebs
CA2368431C (en)	1999-03-29	2006-01-24	The Procter & Gamble Company	Melanocortin receptor ligands
US6316414B1 (en)	2000-07-31	2001-11-13	Dabur Research Foundation	Somatostatin analogs for the treatment of cancer
US8420050B2 (en)	2003-01-13	2013-04-16	Bracco Imaging S.P.A.	Gastrin releasing peptide compounds
US7922998B2 (en)	2003-01-13	2011-04-12	Bracco Imaging S.P.A.	Gastrin releasing peptide compounds
US7850947B2 (en)	2003-01-13	2010-12-14	Bracco Imaging S.P.A.	Gastrin releasing peptide compounds
US7611692B2 (en)	2003-01-13	2009-11-03	Bracco Imaging S.P.A.	Gastrin releasing peptide compounds
US7226577B2 (en)	2003-01-13	2007-06-05	Bracco Imaging, S. P. A.	Gastrin releasing peptide compounds
CN101791409A (zh)	2003-04-22	2010-08-04	研究及应用科学协会股份有限公司	肽载体
EP1913017A1 (de) *	2005-08-03	2008-04-23	Boehringer Ingelheim International GmbH	Substituierte ethan-1,2-diamine zur behandlung von alzheimer-krankheit ii
MX2009002492A (es)	2006-09-08	2009-08-28	Bayer Schering Pharma Ag	Agentes que comprenden compuestos marcados con 18f y metodos relacionados.
CA2727082C (en)	2008-06-12	2019-02-26	Syntaxin Limited	Fusion proteins for use in suppression of acromegaly
CN102083451A (zh)	2008-06-12	2011-06-01	赛恩泰新公司	癌症的抑制
GB0820970D0 (en)	2008-11-17	2008-12-24	Syntaxin Ltd	Suppression of cancer
EP2198878A1 (de)	2008-12-18	2010-06-23	University Of Miami	Polypeptide Bombesinantagonisten

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4207311A (en)	1977-07-18	1980-06-10	The Salk Institute For Biological Studies	Peptides having analgesic and thermoregulative properties

1988
- 1988-09-23 WO PCT/US1988/003286 patent/WO1989002897A1/en not_active Ceased
- 1988-09-23 JP JP63509311A patent/JP2795449B2/ja not_active Expired - Fee Related
- 1988-09-26 DE DE3852086T patent/DE3852086T2/de not_active Expired - Fee Related
- 1988-09-26 EP EP88308916A patent/EP0309297B1/de not_active Expired - Lifetime
- 1988-09-26 ES ES88308916T patent/ES2065336T3/es not_active Expired - Lifetime
- 1988-09-26 AT AT88308916T patent/ATE113961T1/de not_active IP Right Cessation
1989
- 1989-05-23 FI FI892507A patent/FI100719B/fi not_active IP Right Cessation
- 1989-05-23 NO NO892060A patent/NO178306C/no unknown
- 1989-05-23 DK DK249489A patent/DK249489A/da not_active Application Discontinuation

Also Published As

Publication number	Publication date
NO178306C (no)	1996-02-28
FI100719B (fi)	1998-02-13
ES2065336T3 (es)	1995-02-16
EP0309297B1 (de)	1994-11-09
DK249489D0 (da)	1989-05-23
EP0309297A3 (en)	1990-07-04
DE3852086D1 (de)	1994-12-15
JPH02502016A (ja)	1990-07-05
FI892507L (fi)	1989-05-23
AU2710288A (en)	1989-04-18
EP0309297A2 (de)	1989-03-29
FI892507A0 (fi)	1989-05-23
DE3852086T2 (de)	1995-05-18
NO892060L (no)	1989-07-21
DK249489A (da)	1989-07-20
JP2795449B2 (ja)	1998-09-10
NO892060D0 (no)	1989-05-23
AU622123B2 (en)	1992-04-02
WO1989002897A1 (en)	1989-04-06
NO178306B (no)	1995-11-20

Legal Events

Date	Code	Title	Description
1995-05-15	UEP	Publication of translation of european patent specification
2006-06-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
DE3852086D1 (de)	1994-12-15	Therapeutische Peptide.
MC2144A1 (fr)	1992-02-19	Peptides therapeutiques
FI920737A0 (fi)	1992-02-20	Terapeutiska peptider.
PT1288223E (pt)	2005-03-31	Derivados de peptidos terapeuticos
EP0210279A4 (de)	1987-06-19	Stabilisierte menschliche prourokinase.
ES2094160T3 (es)	1997-01-16	Peptidos terapeuticos, en particular analogos del peptido substancia p.
DE3689921D1 (de)	1994-07-21	Menschlicher plazentarer angiogenischer Faktor, geeignet für die Reizung der Kapillarsynthese, der Endothelzellprotease, der DNS-Synthese und der Absiedlung.