ATE114307T1 - Phenylglycidamide, verwendbar in der herstellung von alpha-hydroxy-beta-sulfido-arylpropionsäure- derivaten. - Google Patents

Phenylglycidamide, verwendbar in der herstellung von alpha-hydroxy-beta-sulfido-arylpropionsäure- derivaten.

Info

Publication number: ATE114307T1
Authority: AT; Austria
Prior art keywords: phenylglycidamide; sulfido; usable; production; acid derivatives
Prior art date: 1989-06-14

Application number

AT90306439T

Other languages

English (en)

Inventor

Alvydas Alfonsas Jarmas

Vance John Novack

Original Assignee

Smithkline Beecham Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-06-14

Filing date

1990-06-13

Publication date

1994-12-15

1990-06-13 Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp

1994-12-15 Application granted granted Critical

1994-12-15 Publication of ATE114307T1 publication Critical patent/ATE114307T1/de

Links

IDYVJALWLWIABQ-UHFFFAOYSA-N 2-phenyloxirane-2-carboxamide Chemical compound C=1C=CC=CC=1C1(C(=O)N)CO1 IDYVJALWLWIABQ-UHFFFAOYSA-N 0.000 title 1
239000002253 acid Substances 0.000 title 1
SERHXTVXHNVDKA-UHFFFAOYSA-N pantolactone Chemical compound CC1(C)COC(=O)C1O SERHXTVXHNVDKA-UHFFFAOYSA-N 0.000 title 1
125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 4
125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 3
125000000229 (C1-C4)alkoxy group Chemical group 0.000 abstract 2
150000001875 compounds Chemical class 0.000 abstract 2
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
HSFWRNGVRCDJHI-UHFFFAOYSA-N alpha-acetylene Natural products C#C HSFWRNGVRCDJHI-UHFFFAOYSA-N 0.000 abstract 1
QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
125000000113 cyclohexyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C([H])([H])C1([H])[H] 0.000 abstract 1
125000002534 ethynyl group Chemical group [H]C#C* 0.000 abstract 1
125000002541 furyl group Chemical group 0.000 abstract 1
239000000543 intermediate Substances 0.000 abstract 1
125000000555 isopropenyl group Chemical group [H]\C([H])=C(\*)C([H])([H])[H] 0.000 abstract 1
125000001434 methanylylidene group Chemical group [H]C#[*] 0.000 abstract 1
125000002816 methylsulfanyl group Chemical group [H]C([H])([H])S[*] 0.000 abstract 1
229910052760 oxygen Inorganic materials 0.000 abstract 1
239000001301 oxygen Substances 0.000 abstract 1
229910052717 sulfur Inorganic materials 0.000 abstract 1
239000011593 sulfur Substances 0.000 abstract 1
125000001544 thienyl group Chemical group 0.000 abstract 1
125000005034 trifluormethylthio group Chemical group FC(S*)(F)F 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
- C07C319/14—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/48—Compounds containing oxirane rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms, e.g. ester or nitrile radicals

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Epoxy Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Pyrane Compounds (AREA)
Furan Compounds (AREA)

AT90306439T 1989-06-14 1990-06-13 Phenylglycidamide, verwendbar in der herstellung von alpha-hydroxy-beta-sulfido-arylpropionsäure- derivaten. ATE114307T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US36607889A	1989-06-14	1989-06-14

Publications (1)

Publication Number	Publication Date
ATE114307T1 true ATE114307T1 (de)	1994-12-15

Family

ID=23441578

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT90306439T ATE114307T1 (de)	1989-06-14	1990-06-13	Phenylglycidamide, verwendbar in der herstellung von alpha-hydroxy-beta-sulfido-arylpropionsäure- derivaten.

Country Status (5)

Country	Link
EP (1)	EP0403250B1 (de)
JP (1)	JPH0334974A (de)
AT (1)	ATE114307T1 (de)
DE (1)	DE69014239T2 (de)
PT (1)	PT94376A (de)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4341718A (en) *	1978-07-03	1982-07-27	American Home Products Corporation	α-[(Alkylamino)-methyl]-β-aryloxy-benzeneethanols exhibiting antiarrhythmic activity
EP0358240B1 (de) *	1985-04-19	1993-06-09	Smithkline Beecham Corporation	Zwischenprodukte für die Herstellung von Leukotrien-Antagonisten

1990
- 1990-06-12 PT PT94376A patent/PT94376A/pt not_active Application Discontinuation
- 1990-06-13 AT AT90306439T patent/ATE114307T1/de not_active IP Right Cessation
- 1990-06-13 EP EP90306439A patent/EP0403250B1/de not_active Expired - Lifetime
- 1990-06-13 DE DE69014239T patent/DE69014239T2/de not_active Expired - Fee Related
- 1990-06-14 JP JP2156630A patent/JPH0334974A/ja active Pending

Also Published As

Publication number	Publication date
EP0403250B1 (de)	1994-11-23
DE69014239D1 (de)	1995-01-05
EP0403250A3 (de)	1991-07-31
DE69014239T2 (de)	1995-04-06
JPH0334974A (ja)	1991-02-14
PT94376A (pt)	1991-03-20
EP0403250A2 (de)	1990-12-19

Legal Events

Date	Code	Title	Description
1995-05-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
DE3865504D1 (de)	1991-11-21	1-phenyl-3-naphthalenyloxy-propanamine.
AU635440B2 (en)	1993-03-18	Benzimidazole derivatives, their preparation and use
ES8506718A1 (es)	1985-07-16	Un procedimiento para la preparacion de derivados benzoheterociclicos.
FI845047L (fi)	1985-06-23	Antipsoriatisk naftalenfoerening.
FI861949A0 (fi)	1986-05-09	2,4-difenyl-1,3-dioxaner.
DE69014239D1 (de)	1995-01-05	Phenylglycidamide, verwendbar in der Herstellung von alpha-Hydroxy-beta-sulfido-arylpropionsäure-Derivaten.
DK189988A (da)	1988-10-08	Pyridylalkansyreforbindelser med aktivitet som thromboxan a2-antagonister
ATE36316T1 (de)	1988-08-15	Gegen psoriasis wirkende naphthalin-verbindungen.
ES2063271T3 (es)	1995-01-01	Antagonistas de leucotrienos.
ZA916013B (en)	1992-09-30	Process and intermediate for the preparation of 2-hydroxy-3-sulfido-3-phenyl propanoic acids
PT87616A (pt)	1988-06-01	Process for the preparation of leukotriene antagonists and of pharmaceutical compounds
ATE109454T1 (de)	1994-08-15	Catecholaminester.
SE8400478D0 (sv)	1984-01-31	Oxysalicylamido derivatives