ATE114319T1 - Produktion von proteinen in aktiven formen. - Google Patents

Produktion von proteinen in aktiven formen.

Info

Publication number
ATE114319T1
ATE114319T1 AT88301257T AT88301257T ATE114319T1 AT E114319 T1 ATE114319 T1 AT E114319T1 AT 88301257 T AT88301257 T AT 88301257T AT 88301257 T AT88301257 T AT 88301257T AT E114319 T1 ATE114319 T1 AT E114319T1
Authority
AT
Austria
Prior art keywords
protein
proteins
production
rupturing
active forms
Prior art date
Application number
AT88301257T
Other languages
English (en)
Inventor
Joseph John Patroni
Original Assignee
Southern Cross Biotech Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Southern Cross Biotech Pty Ltd filed Critical Southern Cross Biotech Pty Ltd
Application granted granted Critical
Publication of ATE114319T1 publication Critical patent/ATE114319T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/61—Growth hormone [GH], i.e. somatotropin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/113—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
    • C07K1/1136—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure by reversible modification of the secondary, tertiary or quarternary structure, e.g. using denaturating or stabilising agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Endocrinology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
AT88301257T 1987-02-20 1988-02-16 Produktion von proteinen in aktiven formen. ATE114319T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AUPI046287 1987-02-20

Publications (1)

Publication Number Publication Date
ATE114319T1 true ATE114319T1 (de) 1994-12-15

Family

ID=3772028

Family Applications (1)

Application Number Title Priority Date Filing Date
AT88301257T ATE114319T1 (de) 1987-02-20 1988-02-16 Produktion von proteinen in aktiven formen.

Country Status (10)

Country Link
US (1) US4966963A (de)
EP (1) EP0279619B1 (de)
JP (1) JPS63264598A (de)
AT (1) ATE114319T1 (de)
AU (1) AU612133B2 (de)
CA (1) CA1326106C (de)
DE (1) DE3852140T2 (de)
ES (1) ES2065906T3 (de)
NZ (1) NZ223559A (de)
ZA (1) ZA881067B (de)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU612133B2 (en) * 1987-02-20 1991-07-04 Natinco Nv Production of proteins in active forms
AU609824B2 (en) * 1987-06-15 1991-05-09 Southern Cross Biotech Pty Ltd. Production of proteins in active forms
DE3887521T2 (de) * 1987-06-26 1994-08-18 Commw Scient Ind Res Org Durch virusneutralisierende und schützende monokonale antikörper erkanntes ibdv vp2 epitop.
US5136027A (en) * 1989-05-02 1992-08-04 Abbott Laboratories Method for renaturing proteins in the presence of alkyl sulfate detergents
US5101018A (en) * 1989-06-12 1992-03-31 International Minerals & Chemical Corp. Method for recovering recombinant proteins
DK0432419T3 (da) * 1989-12-05 1994-11-14 American Cyanamid Co Fremgangsmåde til solubilisering og naturering af somatotropiner under anvendelse af lav urinstofkoncentration
AU664021B2 (en) * 1990-09-05 1995-11-02 Natinco Nv Solubilization of proteins in active forms
US6566098B1 (en) * 1990-09-14 2003-05-20 The United States Of America As Represented By The Department Of Health And Human Services DNA encoding truncated hepatocyte growth factor variants
GB2281558B (en) * 1993-09-07 1997-02-19 Joseph Matthew Gaugas Supplying sulphur to plants
US5861372A (en) * 1996-02-22 1999-01-19 The Children's Medical Center Corporation Aggregate angiostatin and method of use
US6346510B1 (en) 1995-10-23 2002-02-12 The Children's Medical Center Corporation Therapeutic antiangiogenic endostatin compositions
US5840838A (en) * 1996-02-29 1998-11-24 University Of Kentucky Research Foundation Process for enhancing the activity of amyloid β peptides
US20030190307A1 (en) 1996-12-24 2003-10-09 Biogen, Inc. Stable liquid interferon formulations
US6566583B1 (en) 1997-06-04 2003-05-20 Daniel Facciotti Schizochytrium PKS genes
ATE498409T1 (de) 1998-08-06 2011-03-15 Mountain View Pharmaceuticals Peg-uricase konjugate und verwendung davon
SG161247A1 (en) 2005-04-11 2010-05-27 Savient Pharmaceuticals Inc Variant forms of urate oxidase and use thereof
US8148123B2 (en) 2005-04-11 2012-04-03 Savient Pharmaceuticals, Inc. Methods for lowering elevated uric acid levels using intravenous injections of PEG-uricase
MX2007012548A (es) 2005-04-11 2008-03-11 Savient Pharmaceuticals Inc Formas variantes de urato oxidasa y uso de las mismas.
US20080159976A1 (en) * 2005-04-11 2008-07-03 Jacob Hartman Methods for lowering elevated uric acid levels using intravenous injections of PEG-uricase
EP1883425A1 (de) * 2005-05-23 2008-02-06 Universite De Geneve Injizierbare superparamagnetische nanoteilchen zur behandlung von hyperthermie und verwendung zur bildung eines hyperthermischen implantats
JP5033177B2 (ja) 2006-04-12 2012-09-26 サビエント ファーマセウティカルズ インク． 陽イオン界面活性剤によるタンパク質の精製
EP2358909B1 (de) 2008-11-17 2015-09-02 Cornell University System zur protokollierung von wechselwirkungen zwischen proteinen im bakteriellen periplasma
US9377454B2 (en) 2009-06-25 2016-06-28 Crealta Pharmaceuticals Llc Methods and kits for predicting infusion reaction risk and antibody-mediated loss of response by monitoring serum uric acid during pegylated uricase therapy
CN116637177A (zh) 2016-11-11 2023-08-25 好利恩治疗美国公司 泼尼松和尿酸酶分子的组合疗法及其用途
WO2020160322A1 (en) 2019-01-30 2020-08-06 Horizon Pharma Rheumatology Llc Tolerization reduces intolerance to pegloticase and prolongs the urate lowering effect (triple)
WO2020160325A1 (en) 2019-01-30 2020-08-06 Horizon Pharma Rheumatology Llc Reducing immunogenicity to pegloticase
US12269875B2 (en) 2023-08-03 2025-04-08 Jeff R. Peterson Gout flare prevention methods using IL-1BETA blockers

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2829089A1 (de) * 1977-07-13 1979-02-01 Sandoz Ag Subunit-vakzine
US4462940A (en) * 1982-09-23 1984-07-31 Cetus Corporation Process for the recovery of human β-interferon-like polypeptides
GR79124B (de) * 1982-12-22 1984-10-02 Genentech Inc
US4731440A (en) * 1985-02-22 1988-03-15 Monsanto Company Method of somatotropin solubilization using dimethylsulfone and naturation
ES8800957A1 (es) * 1985-02-22 1987-12-01 Monsanto Co Un metodo para la solubilizacion y renaturalizacion de proteina somatotropina
US4766224A (en) * 1985-08-19 1988-08-23 International Minerals & Chemical Corp. Purification and activation of proteins from insoluble inclusion bodies
AU597924B2 (en) * 1985-12-11 1990-06-14 Natinco Nv Solubilization of protein aggregates
AU612133B2 (en) * 1987-02-20 1991-07-04 Natinco Nv Production of proteins in active forms
AU607988B2 (en) * 1987-04-21 1991-03-21 Southern Cross Biotech Pty Ltd. Production of proteins in active forms
AU1763188A (en) * 1987-06-15 1988-12-15 Bunge (Australia) Pty Ltd Recovery of proteins in active form

Also Published As

Publication number Publication date
EP0279619A3 (en) 1990-04-11
AU612133B2 (en) 1991-07-04
CA1326106C (en) 1994-01-11
EP0279619A2 (de) 1988-08-24
ZA881067B (en) 1988-08-11
EP0279619B1 (de) 1994-11-23
DE3852140D1 (de) 1995-01-05
NZ223559A (en) 1989-09-27
US4966963A (en) 1990-10-30
AU1141288A (en) 1988-08-25
JPS63264598A (ja) 1988-11-01
DE3852140T2 (de) 1995-04-06
ES2065906T3 (es) 1995-03-01

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EEIH Change in the person of patent owner
REN Ceased due to non-payment of the annual fee