PT93061A - Processo para a preparacao de composicoes farmaceuticas a base de derivados de 5-alquil piridazina, activas sobre o sistema colinergico - Google Patents

Processo para a preparacao de composicoes farmaceuticas a base de derivados de 5-alquil piridazina, activas sobre o sistema colinergico

Info

Publication number: PT93061A
Authority: PT; Portugal
Prior art keywords: pharmaceutical compositions; colinergic; active; compositions based; preparing pharmaceutical
Prior art date: 1989-02-07

Application number

PT93061A

Other languages

English (en)

Other versions

PT93061B (pt

Inventor

Roberto Boigegrain

Camille Georges Wermuth

Paul Worms

Original Assignee

Sanofi Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-02-07

Filing date

1990-02-05

Publication date

1990-08-31

1990-02-05 Application filed by Sanofi Sa filed Critical Sanofi Sa

1990-08-31 Publication of PT93061A publication Critical patent/PT93061A/pt

1995-12-29 Publication of PT93061B publication Critical patent/PT93061B/pt

Links

239000008194 pharmaceutical composition Substances 0.000 title abstract 2
PBMFSQRYOILNGV-UHFFFAOYSA-N pyridazine Chemical class C1=CC=NN=C1 PBMFSQRYOILNGV-UHFFFAOYSA-N 0.000 title 1
125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 2
230000001713 cholinergic effect Effects 0.000 abstract 1
230000001054 cortical effect Effects 0.000 abstract 1
230000007812 deficiency Effects 0.000 abstract 1
230000003412 degenerative effect Effects 0.000 abstract 1
125000004573 morpholin-4-yl group Chemical group N1(CCOCC1)* 0.000 abstract 1
229910052757 nitrogen Inorganic materials 0.000 abstract 1
125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
230000001575 pathological effect Effects 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
230000009758 senescence Effects 0.000 abstract 1
208000011580 syndromic disease Diseases 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/20—Nitrogen atoms

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Psychiatry (AREA)
Hospice & Palliative Care (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

PT93061A 1989-02-07 1990-02-05 Processo para a preparacao de composicoes farmaceuticas a base de derivados de 5-alquil piridazina, activas sobre o sistema colinergico PT93061B (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR8901546A FR2642648B1 (fr)	1989-02-07	1989-02-07	Utilisation de derives d'alkyl-5 pyridazine comme medicaments actifs sur le systeme cholinergique

Publications (2)

Publication Number	Publication Date
PT93061A true PT93061A (pt)	1990-08-31
PT93061B PT93061B (pt)	1995-12-29

Family

ID=9378542

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT93061A PT93061B (pt)	1989-02-07	1990-02-05	Processo para a preparacao de composicoes farmaceuticas a base de derivados de 5-alquil piridazina, activas sobre o sistema colinergico

Country Status (8)

Country	Link
US (1)	US5081119A (pt)
EP (1)	EP0382635B1 (pt)
JP (1)	JPH02240070A (pt)
AT (1)	ATE114469T1 (pt)
CA (1)	CA2009502A1 (pt)
DE (1)	DE69014337D1 (pt)
FR (1)	FR2642648B1 (pt)
PT (1)	PT93061B (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5631255A (en) *	1989-02-07	1997-05-20	Sanofi	Pyridazine derivatives
FR2663326B2 (fr) *	1989-11-17	1992-10-16	Sanofi Sa	Derives de la pyridazine, procede de preparation et compositions pharmaceutiques en contenant.
US5461053A (en) *	1989-02-07	1995-10-24	Sanofi	Pyridazine derivatives
FR2676444B1 (fr) *	1991-05-16	1995-03-10	Sanofi Elf	Nouveaux derives d'amino-3 pyridazines actifs sur le systeme nerveux central, procede de preparation et compositions pharmaceutiques en contenant.
US6699866B2 (en)	2001-04-17	2004-03-02	Sepracor Inc.	Thiazole and other heterocyclic ligands for mammalian dopamine, muscarinic and serotonin receptors and transporters, and methods of use thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1345880A (en) *	1971-06-18	1974-02-06	Cepbepe	Pyridazine derivatives
FR2510998B1 (fr) *	1981-08-07	1986-01-10	Sanofi Sa	Nouveaux derives amines de la pyridazine, leur procede de preparation et les medicaments, a action desinhibitrice, qui en comportent
FR2510997A1 (fr) *	1981-08-10	1983-02-11	Sanofi Sa	Nouveaux derives de la methyl-4 phenyl-6 pyridazine, procede pour leur preparation et medicaments actifs sur le systeme nerveux central en contenant
PT93060B (pt) *	1989-02-07	1995-12-29	Sanofi Sa	Processo para a obtencao de derivados de piridazina e de composicoes farmaceuticas que os contem

1989
- 1989-02-07 FR FR8901546A patent/FR2642648B1/fr not_active Expired - Fee Related
1990
- 1990-02-05 PT PT93061A patent/PT93061B/pt not_active IP Right Cessation
- 1990-02-07 AT AT90400335T patent/ATE114469T1/de not_active IP Right Cessation
- 1990-02-07 CA CA002009502A patent/CA2009502A1/en not_active Abandoned
- 1990-02-07 US US07/475,490 patent/US5081119A/en not_active Expired - Fee Related
- 1990-02-07 DE DE69014337T patent/DE69014337D1/de not_active Expired - Lifetime
- 1990-02-07 EP EP90400335A patent/EP0382635B1/fr not_active Expired - Lifetime
- 1990-02-07 JP JP2028148A patent/JPH02240070A/ja active Pending

Also Published As

Publication number	Publication date
EP0382635A3 (fr)	1992-01-08
JPH02240070A (ja)	1990-09-25
DE69014337D1 (de)	1995-01-12
CA2009502A1 (en)	1990-08-07
EP0382635B1 (fr)	1994-11-30
ATE114469T1 (de)	1994-12-15
FR2642648A1 (fr)	1990-08-10
US5081119A (en)	1992-01-14
FR2642648B1 (fr)	1991-06-21
PT93061B (pt)	1995-12-29
EP0382635A2 (fr)	1990-08-16

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Legal Events

Date

Code

Title

Description

1995-12-29

FG3A

Patent granted, date of granting

Effective date: 19950911

1999-07-30

MM3A

Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19990331