ATE116330T1 - Fluorogene peptide und deren verwendung in der bestimmung enzymatischer aktivitäten. - Google Patents

Fluorogene peptide und deren verwendung in der bestimmung enzymatischer aktivitäten.

Info

Publication number
ATE116330T1
ATE116330T1 AT91908699T AT91908699T ATE116330T1 AT E116330 T1 ATE116330 T1 AT E116330T1 AT 91908699 T AT91908699 T AT 91908699T AT 91908699 T AT91908699 T AT 91908699T AT E116330 T1 ATE116330 T1 AT E116330T1
Authority
AT
Austria
Prior art keywords
peptide
amino acid
residue
group
peptides
Prior art date
Application number
AT91908699T
Other languages
English (en)
Inventor
Morten Meldal
Klaus Breddam
Original Assignee
Carlsberg As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Carlsberg As filed Critical Carlsberg As
Application granted granted Critical
Publication of ATE116330T1 publication Critical patent/ATE116330T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1016—Tetrapeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Laminated Bodies (AREA)
  • Position Input By Displaying (AREA)
  • Manufacturing Of Electric Cables (AREA)
AT91908699T 1990-04-17 1991-04-16 Fluorogene peptide und deren verwendung in der bestimmung enzymatischer aktivitäten. ATE116330T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK093990A DK93990D0 (da) 1990-04-17 1990-04-17 Fluorogene peptider og deres anvendelse ved bestemmelse af enzymatisk aktivitet

Publications (1)

Publication Number Publication Date
ATE116330T1 true ATE116330T1 (de) 1995-01-15

Family

ID=8099218

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91908699T ATE116330T1 (de) 1990-04-17 1991-04-16 Fluorogene peptide und deren verwendung in der bestimmung enzymatischer aktivitäten.

Country Status (8)

Country Link
EP (1) EP0528854B1 (de)
JP (1) JPH05506235A (de)
AT (1) ATE116330T1 (de)
AU (1) AU634395B2 (de)
CA (1) CA2080694A1 (de)
DE (1) DE69106358D1 (de)
DK (1) DK93990D0 (de)
WO (1) WO1991016336A1 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU5957794A (en) * 1992-12-21 1994-07-19 Uab Research Foundation, The Compositions and method for the inhibition of phagocytes
GB9310978D0 (en) * 1993-05-27 1993-07-14 Zeneca Ltd Compounds
JP4043535B2 (ja) * 1994-06-21 2008-02-06 サントリー株式会社 ペプチド基質並びにこれを用いるプロテイナーゼａ活性およびビールの泡安定性の測定方法
CA2158782C (en) * 1994-09-23 2010-01-12 Pierrette Gaudreau Marker for growth hormone-releasing factor receptors
US6008373A (en) * 1995-06-07 1999-12-28 Carnegie Mellon University Fluorescent labeling complexes with large stokes shift formed by coupling together cyanine and other fluorochromes capable of resonance energy transfer
GB9525403D0 (en) * 1995-12-13 1996-02-14 Univ Sunderland Method for monitoring enzymes
EP1019528B1 (de) * 1996-01-04 2003-10-29 Nederlandse Organisatie Voor Toegepast-Natuurwetenschappelijk Onderzoek Tno Methode zur bestimmung von proteolytischen enzyme unter benutzung von fluoreszenzgelöschten substraten
WO1997042216A1 (en) * 1996-04-24 1997-11-13 Peptide Therapeutics Limited Auto-deconvoluting combinatorial libraries
AU733007B2 (en) * 1996-09-24 2001-05-03 Cadus Pharmaceutical Corporation Methods and compositions for identifying receptor effectors
US20030096315A1 (en) 2000-05-03 2003-05-22 Sanders Mitchell C. Device for detecting bacterial contamination and method of use
ES2271078T3 (es) * 2000-05-03 2007-04-16 Expressive Constructs, Inc. Metodo para detectar listeria monocytogenes.
JP2005528887A (ja) 2002-01-31 2005-09-29 エクスプレッシブ コンストラクツ，インコーポレイテッド 微生物の検出方法
GB0208989D0 (en) * 2002-04-19 2002-05-29 Amersham Biosciences Uk Ltd Methods for measuring enzyme activity
GB2398123B (en) * 2002-04-19 2005-03-02 Amersham Biosciences Uk Ltd Methods for measuring enzyme activity
US6821744B2 (en) 2002-10-29 2004-11-23 Roche Diagnostics Operations, Inc. Method, assay, and kit for quantifying HIV protease inhibitors
CN1902494B (zh) 2003-11-03 2010-10-27 伊西康公司 用于检测广谱细菌的方法、肽和生物传感器
JP2006322858A (ja) * 2005-05-19 2006-11-30 Kyushu Univ タンパク質蛍光標識方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL60888A (en) * 1978-06-16 1984-07-31 Yeda Res & Dev Substrates and process for the quantitative assay of enzymes
ATE79635T1 (de) * 1986-04-01 1992-09-15 Wako Pure Chem Ind Ltd Peptid-derivate und methode zur messung der wirksamkeit von physiologisch aktiven verbindungen, die dieselben als substraten benuetzen.

Also Published As

Publication number Publication date
AU634395B2 (en) 1993-02-18
EP0528854A1 (de) 1993-03-03
EP0528854B1 (de) 1994-12-28
DK93990D0 (da) 1990-04-17
CA2080694A1 (en) 1991-10-18
DE69106358D1 (de) 1995-02-09
JPH05506235A (ja) 1993-09-16
AU7751391A (en) 1991-11-11
WO1991016336A1 (en) 1991-10-31

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