ATE116548T1 - Methode für die änderung der bindung eines zelladhäsionrezeptors. - Google Patents
Methode für die änderung der bindung eines zelladhäsionrezeptors.Info
- Publication number
- ATE116548T1 ATE116548T1 AT89911334T AT89911334T ATE116548T1 AT E116548 T1 ATE116548 T1 AT E116548T1 AT 89911334 T AT89911334 T AT 89911334T AT 89911334 T AT89911334 T AT 89911334T AT E116548 T1 ATE116548 T1 AT E116548T1
- Authority
- AT
- Austria
- Prior art keywords
- binding
- increase
- receptors
- cations
- altering
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 4
- 102000019997 adhesion receptor Human genes 0.000 title 1
- 108010013985 adhesion receptor Proteins 0.000 title 1
- 230000021164 cell adhesion Effects 0.000 title 1
- 150000001768 cations Chemical class 0.000 abstract 3
- 239000003446 ligand Substances 0.000 abstract 3
- 102000005962 receptors Human genes 0.000 abstract 3
- 108020003175 receptors Proteins 0.000 abstract 3
- 102100037362 Fibronectin Human genes 0.000 abstract 2
- 108010044426 integrins Proteins 0.000 abstract 2
- 102000006495 integrins Human genes 0.000 abstract 2
- 108010048623 Collagen Receptors Proteins 0.000 abstract 1
- 238000002965 ELISA Methods 0.000 abstract 1
- 108010017707 Fibronectin Receptors Proteins 0.000 abstract 1
- 108010067306 Fibronectins Proteins 0.000 abstract 1
- 102100025305 Integrin alpha-2 Human genes 0.000 abstract 1
- 102100022337 Integrin alpha-V Human genes 0.000 abstract 1
- 102000007547 Laminin Human genes 0.000 abstract 1
- 108010085895 Laminin Proteins 0.000 abstract 1
- 102100035140 Vitronectin Human genes 0.000 abstract 1
- 108010031318 Vitronectin Proteins 0.000 abstract 1
- 108010048673 Vitronectin Receptors Proteins 0.000 abstract 1
- 238000003556 assay Methods 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 abstract 1
- 230000003247 decreasing effect Effects 0.000 abstract 1
- 239000011159 matrix material Substances 0.000 abstract 1
- 238000013508 migration Methods 0.000 abstract 1
- 230000005012 migration Effects 0.000 abstract 1
- 239000000758 substrate Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70546—Integrin superfamily
- C07K14/7055—Integrin beta1-subunit-containing molecules, e.g. CD29, CD49
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/244—Lanthanides; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/5306—Improving reaction conditions, e.g. reduction of non-specific binding, promotion of specific binding
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Molecular Biology (AREA)
- Inorganic Chemistry (AREA)
- Epidemiology (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Organic Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- General Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US24470188A | 1988-09-14 | 1988-09-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE116548T1 true ATE116548T1 (de) | 1995-01-15 |
Family
ID=22923789
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT89911334T ATE116548T1 (de) | 1988-09-14 | 1989-09-13 | Methode für die änderung der bindung eines zelladhäsionrezeptors. |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP0435946B1 (de) |
| JP (1) | JPH04501715A (de) |
| AT (1) | ATE116548T1 (de) |
| DE (1) | DE68920439T2 (de) |
| WO (1) | WO1990002556A1 (de) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3901458A1 (de) * | 1989-01-19 | 1990-07-26 | Behringwerke Ag | Verwendung von zwei- oder dreiwertigen kationen in immunchemischen tests |
| US6572896B1 (en) * | 1998-01-30 | 2003-06-03 | A.T. Still University Of Health Sciences | Methods for inhibiting cell motility |
| JP2003500023A (ja) | 1999-04-30 | 2003-01-07 | バイオストラタム インコーポレイテッド | ラミニン８及びその使用方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4614517A (en) * | 1982-08-04 | 1986-09-30 | La Jolla Cancer Research Foundation | Tetrapeptide |
| US4578079A (en) * | 1982-08-04 | 1986-03-25 | La Jolla Cancer Research Foundation | Tetrapeptide |
| US4683291A (en) * | 1985-10-28 | 1987-07-28 | Scripps Clinic And Research Foundation | Platelet binding inhibitors |
-
1989
- 1989-09-13 DE DE68920439T patent/DE68920439T2/de not_active Expired - Fee Related
- 1989-09-13 EP EP89911334A patent/EP0435946B1/de not_active Expired - Lifetime
- 1989-09-13 WO PCT/US1989/003979 patent/WO1990002556A1/en not_active Ceased
- 1989-09-13 AT AT89911334T patent/ATE116548T1/de not_active IP Right Cessation
- 1989-09-13 JP JP1510549A patent/JPH04501715A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| WO1990002556A1 (en) | 1990-03-22 |
| JPH04501715A (ja) | 1992-03-26 |
| DE68920439T2 (de) | 1995-05-11 |
| EP0435946A1 (de) | 1991-07-10 |
| EP0435946B1 (de) | 1995-01-04 |
| DE68920439D1 (de) | 1995-02-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |