ATE116548T1 - Methode für die änderung der bindung eines zelladhäsionrezeptors. - Google Patents

Methode für die änderung der bindung eines zelladhäsionrezeptors.

Info

Publication number
ATE116548T1
ATE116548T1 AT89911334T AT89911334T ATE116548T1 AT E116548 T1 ATE116548 T1 AT E116548T1 AT 89911334 T AT89911334 T AT 89911334T AT 89911334 T AT89911334 T AT 89911334T AT E116548 T1 ATE116548 T1 AT E116548T1
Authority
AT
Austria
Prior art keywords
binding
increase
receptors
cations
altering
Prior art date
Application number
AT89911334T
Other languages
English (en)
Inventor
Erkki I Ruoslahti
James O Gailit
Kurt R Gehlsen
Aarno Hautanen
Michael D Pierschbacher
Original Assignee
Jolla Cancer Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jolla Cancer Res Found filed Critical Jolla Cancer Res Found
Application granted granted Critical
Publication of ATE116548T1 publication Critical patent/ATE116548T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70546—Integrin superfamily
    • C07K14/7055—Integrin beta1-subunit-containing molecules, e.g. CD29, CD49
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/244—Lanthanides; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5306—Improving reaction conditions, e.g. reduction of non-specific binding, promotion of specific binding
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Inorganic Chemistry (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Organic Chemistry (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT89911334T 1988-09-14 1989-09-13 Methode für die änderung der bindung eines zelladhäsionrezeptors. ATE116548T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US24470188A 1988-09-14 1988-09-14

Publications (1)

Publication Number Publication Date
ATE116548T1 true ATE116548T1 (de) 1995-01-15

Family

ID=22923789

Family Applications (1)

Application Number Title Priority Date Filing Date
AT89911334T ATE116548T1 (de) 1988-09-14 1989-09-13 Methode für die änderung der bindung eines zelladhäsionrezeptors.

Country Status (5)

Country Link
EP (1) EP0435946B1 (de)
JP (1) JPH04501715A (de)
AT (1) ATE116548T1 (de)
DE (1) DE68920439T2 (de)
WO (1) WO1990002556A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3901458A1 (de) * 1989-01-19 1990-07-26 Behringwerke Ag Verwendung von zwei- oder dreiwertigen kationen in immunchemischen tests
US6572896B1 (en) * 1998-01-30 2003-06-03 A.T. Still University Of Health Sciences Methods for inhibiting cell motility
WO2000066732A2 (en) * 1999-04-30 2000-11-09 Biostratum, Inc. Laminin 8 and methods for its use

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4614517A (en) * 1982-08-04 1986-09-30 La Jolla Cancer Research Foundation Tetrapeptide
US4578079A (en) * 1982-08-04 1986-03-25 La Jolla Cancer Research Foundation Tetrapeptide
US4683291A (en) * 1985-10-28 1987-07-28 Scripps Clinic And Research Foundation Platelet binding inhibitors

Also Published As

Publication number Publication date
DE68920439T2 (de) 1995-05-11
WO1990002556A1 (en) 1990-03-22
JPH04501715A (ja) 1992-03-26
EP0435946B1 (de) 1995-01-04
DE68920439D1 (de) 1995-02-16
EP0435946A1 (de) 1991-07-10

Similar Documents

Publication Publication Date Title
Miles et al. Promotion of cell adhesion by single-stranded and triple-helical peptide models of basement membrane collagen alpha 1 (IV) 531-543. Evidence for conformationally dependent and conformationally independent type IV collagen cell adhesion sites.
ATE127923T1 (de) Elektrochemilumineszenz-testverfahren.
AR008919A1 (es) Anticuerpos anti-cd11a humanizados.
DE3684741D1 (de) Quadratfarbstoffkonjugat, dessen herstellungsverfahren und dessen verwendung bei testverfahren sowie testsaetze.
DE69131556D1 (de) Zusammensetzung zum verbinden und abdichten von geweben und verfahren zu ihrer verwendung
ATE123810T1 (de) Alpha-subeinheit des lfa-1-leukocyt-adhäsions- rezeptors.
DE3382495D1 (de) Protein-a material und dessen herstellung.
NO891375D0 (no) Nye polypeptider med vekstfaktoraktivitet og nukleinsyresekvenser som koder for polypeptidene.
PT1019420E (pt) Metodos para a producao de ligandos baseados em platina para ligacao entre marcadores e moleculas bio-orgaicas na marcacao de moleculas bio-organicas com o fim de detectar substancias biologicas de interesse e conjuntos ("kits") de ensaios de diagnosticos
Stoltz et al. Hemorheology and vascular endothelial cells: Opening lecture
Persson et al. The gamma-carboxyglutamic acid and epidermal growth factor-like domains of factor X. Effect of isolated domains on prothrombin activation and endothelial cell binding of factor X
ATE116548T1 (de) Methode für die änderung der bindung eines zelladhäsionrezeptors.
DE69033220D1 (de) Immunoassays für und monoklonale antikörper gegen prothrombin-aktivierende peptide und ihre abbauprodukte
TR26082A (tr) KROMOTOGRAFIK AYIRIM ICIN LIGAND IHTIVA EDEN ORTAM BU ORTAMI HAZIRLAMAYA MAHSUS YÖNTEM VE BU ORTAMIN BIR AKISKAN KARISIMINDAN SENTETIK VEYA DOGAL MOLEKüLLERI AYIRMAK ICIN KULLANILMASI
DE68926658D1 (de) Diagnostische gene zum nachweis von toxoplasmose
AR016681A1 (es) Deplecion de celulas th2; composiciones; metodos
WO1994000599A3 (en) Process for detection of neoplastic disease
DE69930843D1 (de) Verfahren zum bestimmen von autoantikörpern
Ryrie et al. Transmembrane organization of individual polypeptides of photosystem I complex and the light-harvesting complex of photosystem II of thylakoid membranes
ES2002685A4 (es) Produccion de activador de plasminogeno a partir de celulas normales de colon humano.
DE69505365D1 (de) Immunologisches verfahren zum nachweis von glykosaminoglykan-aktiviertem antithrombin iii; die entsprechenden monoklonalen antikörper und deren herstellung
DE3871530D1 (de) Vorrichtung zum kultivieren von ruhenden zellen in einem bioreaktor.
ATE110853T1 (de) Immuntestverfahren für zelluläres eiweiss.
DE69004964D1 (de) Zellenzuchtverfahren für die produktion von aktiviertem protein-c.
ATE28861T1 (de) Chloramphenicol-derivate, zwischenprodukt und verfahren dazu.

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee