ATE116687T1 - Stamm ral-4, nützlich zur herstellung kleiner proteine und peptide. - Google Patents

Stamm ral-4, nützlich zur herstellung kleiner proteine und peptide.

Info

Publication number
ATE116687T1
ATE116687T1 AT91903044T AT91903044T ATE116687T1 AT E116687 T1 ATE116687 T1 AT E116687T1 AT 91903044 T AT91903044 T AT 91903044T AT 91903044 T AT91903044 T AT 91903044T AT E116687 T1 ATE116687 T1 AT E116687T1
Authority
AT
Austria
Prior art keywords
ral
peptides
strain
useful
proteins
Prior art date
Application number
AT91903044T
Other languages
English (en)
Inventor
Robert Alan Lepley
Eric Robert Olson
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Application granted granted Critical
Publication of ATE116687T1 publication Critical patent/ATE116687T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/65—Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/60—Growth hormone-releasing factor [GH-RF], i.e. somatoliberin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C12N15/71—Expression systems using regulatory sequences derived from the trp-operon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/185—Escherichia
    • C12R2001/19—Escherichia coli

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Endocrinology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT91903044T 1990-01-31 1991-01-18 Stamm ral-4, nützlich zur herstellung kleiner proteine und peptide. ATE116687T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US47264090A 1990-01-31 1990-01-31

Publications (1)

Publication Number Publication Date
ATE116687T1 true ATE116687T1 (de) 1995-01-15

Family

ID=23876348

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91903044T ATE116687T1 (de) 1990-01-31 1991-01-18 Stamm ral-4, nützlich zur herstellung kleiner proteine und peptide.

Country Status (10)

Country Link
EP (1) EP0514405B1 (de)
JP (1) JPH05504063A (de)
AT (1) ATE116687T1 (de)
AU (2) AU643752B2 (de)
CA (1) CA2070994A1 (de)
DE (1) DE69106498T2 (de)
DK (1) DK0514405T3 (de)
ES (1) ES2069277T3 (de)
GR (1) GR3015629T3 (de)
WO (1) WO1991011523A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9712818D0 (en) * 1996-07-08 1997-08-20 Cambridge Antibody Tech Labelling and selection of specific binding molecules
EP0972838B1 (de) * 1998-07-15 2004-09-15 Roche Diagnostics GmbH Escherichia coli Wirt/Vektorsystem basierend auf einer antibiotikafreien Selektion durch Komplementation einer Auxotrophie
US6291245B1 (en) 1998-07-15 2001-09-18 Roche Diagnostics Gmbh Host-vector system
US6656721B1 (en) 2000-08-08 2003-12-02 Roche Vitamins, Inc. Polynucleotide portions of the biotin operon from B. subtilis for use in enhanced fermentation
AU2003295182B9 (en) * 2003-12-23 2009-12-17 Council Of Scientific And Industrial Research Process for producing streptokinase using genetically modified Escherichia coli

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5685289A (en) * 1979-12-13 1981-07-11 Ajinomoto Co Inc Preparation of l-valine by fermentation
JPS6078590A (ja) * 1983-10-07 1985-05-04 Ajinomoto Co Inc 発酵法によるｌ−フエニルアラニンの製造法
CA1338664C (en) * 1985-04-10 1996-10-22 Cetus Oncology Corporation Recombinant hosts
AU7512287A (en) * 1986-05-20 1987-12-22 Dana-Farber Cancer Institute Expression of human t-cell lymphotropic virus (htlv-iii)reve rse transcriptase and uses thereof
WO1988006186A2 (en) * 1987-02-19 1988-08-25 The Upjohn Company cDNAs ENCODING SOMATOTROPIN, EXPRESSION VECTORS AND HOSTS

Also Published As

Publication number Publication date
DE69106498D1 (de) 1995-02-16
CA2070994A1 (en) 1991-08-01
EP0514405A1 (de) 1992-11-25
EP0514405B1 (de) 1995-01-04
GR3015629T3 (en) 1995-06-30
AU7184091A (en) 1991-08-21
AU4181593A (en) 1993-09-30
AU658312B2 (en) 1995-04-06
AU643752B2 (en) 1993-11-25
DK0514405T3 (da) 1995-07-10
DE69106498T2 (de) 1995-05-24
ES2069277T3 (es) 1995-05-01
JPH05504063A (ja) 1993-07-01
WO1991011523A1 (en) 1991-08-08

Similar Documents

Publication Publication Date Title
ES2120964T3 (es) Peptidos osteogenicos.
ATE138102T1 (de) Verfahren zur herstellung von cysteinfreien peptiden
DK263689A (da) Modificeret baculovirus, fremgangsmaade til dets fremstilling samt dets anvendelse som ekspressionsvektor for gener
BR9607464B1 (pt) variante artificial da seqÜÊncia sinal de secreÇço stii.
EA199900355A1 (ru) Теломераза обратная тринскриптаза
EP1798239A3 (de) G-Protein-gekoppelte Rezeptoren und deren Verwendung
ATE527364T1 (de) Polypeptide erhaltend eine modifizierte menschliche serum-albumin sekretions-pre-sequenz mit erhöhtem ausscheidungsertrag
NZ215260A (en) Method of expressing eucaryotic genes in procaryotic organisms
ATE404668T1 (de) Wachstumsfaktor-homologe zvegf-3
DE69131929D1 (de) Methoden zur trans-destabilisierung von spezifischen proteinen in vivo
ATE364703T1 (de) Herstellung von proteinen aus pro-proteinen durch fusionsproteine abgeleitet von furin oder furinanalogen
ES2109217T3 (es) Determinante peptidico asociado con la inmunidad.
DK0434605T3 (da) Ny fremgangsmåde til fremstilling af ikke-fusioneret protein i E.coli
ATE116687T1 (de) Stamm ral-4, nützlich zur herstellung kleiner proteine und peptide.
DE3785798D1 (de) Verfahren zur gentechnologischengewinnung von proteinen unter verwendung gramnegativer wirtzellen.
WO2000006706A3 (en) Map kinase phosphatase mutant
KR950005991A (ko) 섬자리공 항바이러스성 단백질(pip) 유전자 및 이를 발현하는 미생물
DK595187D0 (da) Minactivin og fremgangsmaade til fremstilling deraf
DE59109235D1 (de) Peptide des HIV-gag Proteins, ihre Herstellung und Verwendung
EP0750040A3 (de) Varianten des Makrophagen-stimulierendes-Proteins und Verfahren zur ihrer Herstellung
DK0828004T3 (da) Proteindisulfidisomerase-gen afledt af stamme af methylotrof gær
ATE81675T1 (de) Produktion eines proteins.
FR2777292B1 (fr) Nouvelles constructions pour l'expression controlee de proteines recombinantes dans des cellules procaryotes
DE59409341D1 (de) Verfahren zur rekombinanten herstellung von proteinen in hefe
DE69032453D1 (de) Expressionsvektoren und verfahren zur herstellung intrazellularer proteine

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee