ATE118040T1 - Thermostabile cytosin deaminase. - Google Patents

Thermostabile cytosin deaminase.

Info

Publication number: ATE118040T1
Authority: AT; Austria
Prior art keywords: cdase; thermally stable; cytosine deaminase; kda; molecular weight
Prior art date: 1989-06-09

Application number

AT90306131T

Other languages

English (en)

Inventor

Peter Dana Senter

Peter Chong-Dug Su

Hans Marquardt

Martha S Hayden

Peter Linsley

Original Assignee

Oncogen

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-06-09

Filing date

1990-06-06

Publication date

1995-02-15

1990-06-01 Priority claimed from US07/531,646 external-priority patent/US5338678A/en

1990-06-06 Application filed by Oncogen filed Critical Oncogen

1995-02-15 Application granted granted Critical

1995-02-15 Publication of ATE118040T1 publication Critical patent/ATE118040T1/de

Links

102000000311 Cytosine Deaminase Human genes 0.000 title abstract 5
108010080611 Cytosine Deaminase Proteins 0.000 title abstract 5
240000004808 Saccharomyces cerevisiae Species 0.000 abstract 3
235000014680 Saccharomyces cerevisiae Nutrition 0.000 abstract 3
108090000623 proteins and genes Proteins 0.000 abstract 2
102000004190 Enzymes Human genes 0.000 abstract 1
108090000790 Enzymes Proteins 0.000 abstract 1
238000001641 gel filtration chromatography Methods 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
102000004169 proteins and genes Human genes 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Zoology (AREA)
Genetics & Genomics (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Organic Chemistry (AREA)
Wood Science & Technology (AREA)
General Engineering & Computer Science (AREA)
Biomedical Technology (AREA)
Biotechnology (AREA)
Medicinal Chemistry (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
General Health & Medical Sciences (AREA)
Microbiology (AREA)
Enzymes And Modification Thereof (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)

AT90306131T 1989-06-09 1990-06-06 Thermostabile cytosin deaminase. ATE118040T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US36502089A	1989-06-09	1989-06-09
US07/531,646 US5338678A (en)	1989-06-09	1990-06-01	Expression of DNA sequences encoding a thermally stable cytosine deaminase from saccharomyces

Publications (1)

Publication Number	Publication Date
ATE118040T1 true ATE118040T1 (de)	1995-02-15

Family

ID=27002759

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT90306131T ATE118040T1 (de)	1989-06-09	1990-06-06	Thermostabile cytosin deaminase.

Country Status (21)

Country	Link
US (1)	US5545548A (de)
EP (1)	EP0402108B1 (de)
JP (1)	JP3001933B2 (de)
CN (1)	CN1052263C (de)
AT (1)	ATE118040T1 (de)
CA (1)	CA2018273C (de)
CZ (1)	CZ283492B6 (de)
DE (1)	DE69016502T2 (de)
DK (1)	DK0402108T3 (de)
ES (1)	ES2070277T3 (de)
FI (1)	FI95046C (de)
GR (1)	GR3015207T3 (de)
IE (1)	IE66054B1 (de)
IL (1)	IL94649A (de)
MY (1)	MY105816A (de)
NO (1)	NO301487B1 (de)
NZ (1)	NZ233949A (de)
OA (1)	OA09214A (de)
PL (1)	PL165149B1 (de)
PT (1)	PT94331B (de)
YU (1)	YU112090A (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6555370B1 (en)	1990-11-13	2003-04-29	Immunex Corporation	Bifunctional selectable fusion genes
US5358866A (en) *	1991-07-03	1994-10-25	The United States Of America As Represented By The Department Of Health And Human Services	Cytosine deaminase negative selection system for gene transfer techniques and therapies
AU6953394A (en) *	1993-05-21	1994-12-20	Targeted Genetics Corporation	Bifunctional selectable fusion genes based on the cytosine deaminase (cd) gene
US6451571B1 (en)	1994-05-02	2002-09-17	University Of Washington	Thymidine kinase mutants
US5856153A (en) *	1994-11-17	1999-01-05	Cayla	Suicide genes and new associations of pyrimidine nucleobase and nucleoside analogs with new suicide genes for gene therapy of acquired diseases
US6346379B1 (en)	1997-09-11	2002-02-12	F. Hoffman-La Roche Ag	Thermostable DNA polymerases incorporating nucleoside triphosphates labeled with fluorescein family dyes
GB9810752D0 (en) *	1998-05-19	1998-07-15	Glaxo Group Ltd	Cystosine deaminase gene
US6962702B2 (en)	1998-06-22	2005-11-08	Immunomedics Inc.	Production and use of novel peptide-based agents for use with bi-specific antibodies
US8716558B2 (en)	1999-06-30	2014-05-06	Marker Gene Technologies, Inc.	Method of altering glycosylation of proteins in response to nojirimycin glucuronide in a plant cell expressing glucuronidase
US6656917B1 (en) *	1999-06-30	2003-12-02	Marker Gene Technologies, Inc.	Compositions and methods for targeted enzymatic release of cell regulatory compounds
US20060147420A1 (en)	2004-03-10	2006-07-06	Juan Fueyo	Oncolytic adenovirus armed with therapeutic genes
KR20120068769A (ko)	2002-07-15	2012-06-27	더 보드 오브 리전츠 오브 더 유니버시티 오브 텍사스 시스템	음이온성 인지질 및 아미노인지질에 결합하는 선택된 항체 및 치료하는데 있어서 이의 용도
ATE500267T1 (de)	2003-07-21	2011-03-15	Transgene Sa	Multifunktionelle cytokine
JP4672659B2 (ja) *	2003-07-21	2011-04-20	トランジェーヌ、ソシエテ、アノニム	改善されたシトシンデアミナーゼ活性を有するポリペプチド
CA2534639C (en)	2003-07-31	2013-07-30	Immunomedics, Inc.	Anti-cd19 antibodies
DK1760148T3 (da) *	2004-04-28	2013-09-02	Amano Enzyme Inc	Amp-deaminase, som stammer fra streptomyces og brugen deraf
CA2705152C (en)	2007-11-09	2016-10-11	Peregrine Pharmaceuticals, Inc.	Anti-vegf antibody compositions and methods
US20090263884A1 (en) *	2008-04-22	2009-10-22	Organica Biotech, Inc.	Multi-action drain cleaning composition and method
CN102227503B (zh)	2008-09-26	2015-10-21	托卡根公司	重组载体
CN103031296B (zh) *	2012-12-10	2014-12-17	浙江工业大学	冬虫夏草dCMP脱氨酶、编码基因及其应用
CN103045573B (zh) *	2012-12-10	2015-03-18	浙江工业大学	冬虫夏草胞嘧啶脱氨酶、编码基因及其应用
CN109207535B (zh) *	2018-09-20	2021-06-25	新乡拓新药业股份有限公司	利用铜绿假单胞菌合成尿嘧啶的方法
CN116143947B (zh) *	2023-01-16	2024-05-24	中国科学院青岛生物能源与过程研究所	一种酵母胞嘧啶脱氨酶融合蛋白及其突变体和应用

1990
- 1990-06-05 CA CA002018273A patent/CA2018273C/en not_active Expired - Lifetime
- 1990-06-06 ES ES90306131T patent/ES2070277T3/es not_active Expired - Lifetime
- 1990-06-06 DE DE69016502T patent/DE69016502T2/de not_active Expired - Lifetime
- 1990-06-06 DK DK90306131.5T patent/DK0402108T3/da active
- 1990-06-06 AT AT90306131T patent/ATE118040T1/de not_active IP Right Cessation
- 1990-06-06 EP EP90306131A patent/EP0402108B1/de not_active Expired - Lifetime
- 1990-06-06 IL IL9464990A patent/IL94649A/en active IP Right Grant
- 1990-06-06 NZ NZ233949A patent/NZ233949A/en unknown
- 1990-06-07 FI FI902855A patent/FI95046C/fi active IP Right Grant
- 1990-06-08 CZ CS902865A patent/CZ283492B6/cs not_active IP Right Cessation
- 1990-06-08 PL PL90285552A patent/PL165149B1/pl unknown
- 1990-06-08 NO NO902551A patent/NO301487B1/no not_active IP Right Cessation
- 1990-06-08 MY MYPI90000950A patent/MY105816A/en unknown
- 1990-06-08 OA OA59803A patent/OA09214A/xx unknown
- 1990-06-08 IE IE207990A patent/IE66054B1/en not_active IP Right Cessation
- 1990-06-08 PT PT94331A patent/PT94331B/pt not_active IP Right Cessation
- 1990-06-08 YU YU01120/90A patent/YU112090A/xx unknown
- 1990-06-09 CN CN90104922A patent/CN1052263C/zh not_active Expired - Lifetime
- 1990-06-11 JP JP2153799A patent/JP3001933B2/ja not_active Expired - Lifetime
1994
- 1994-06-20 US US08/262,238 patent/US5545548A/en not_active Expired - Lifetime
1995
- 1995-02-28 GR GR940403976T patent/GR3015207T3/el unknown

Also Published As

Publication number	Publication date
NO902551D0 (no)	1990-06-08
PT94331A (pt)	1991-03-20
MY105816A (en)	1995-01-30
CA2018273A1 (en)	1990-12-09
JP3001933B2 (ja)	2000-01-24
FI95046B (fi)	1995-08-31
DK0402108T3 (da)	1995-04-10
PL165149B1 (pl)	1994-11-30
GR3015207T3 (en)	1995-05-31
NO902551L (no)	1990-12-10
IE66054B1 (en)	1995-12-13
YU112090A (en)	1992-05-28
CS286590A3 (en)	1992-02-19
NZ233949A (en)	1992-06-25
DE69016502D1 (de)	1995-03-16
FI95046C (fi)	1995-12-11
US5545548A (en)	1996-08-13
IL94649A0 (en)	1991-04-15
CN1050221A (zh)	1991-03-27
ES2070277T3 (es)	1995-06-01
NO301487B1 (no)	1997-11-03
JPH04131084A (ja)	1992-05-01
CZ283492B6 (cs)	1998-04-15
CN1052263C (zh)	2000-05-10
PL285552A1 (en)	1991-02-25
PT94331B (pt)	1997-04-30
IE902079L (en)	1990-12-09
CA2018273C (en)	1999-04-06
DE69016502T2 (de)	1995-06-01
OA09214A (en)	1992-06-30
FI902855A0 (fi)	1990-06-07
EP0402108A1 (de)	1990-12-12
EP0402108B1 (de)	1995-02-01
IL94649A (en)	1995-11-27

Legal Events

Date	Code	Title	Description
1995-06-15	UEP	Publication of translation of european patent specification
2010-09-15	EELA	Cancelled due to lapse of time

Publication	Publication Date	Title
DE69016502D1 (de)	1995-03-16	Thermostabile Cytosin deaminase.
KR910001064A (ko)	1991-01-30	열 안정성을 갖는 시토신 탈(脫) 아민 효소
DE69828193D1 (de)	2005-01-20	Hyaluronan synthase gen und seine verwendung
NO981168L (no)	1998-05-08	Renset mannanase fra Bacillus amyloliquefaciens, samt framgangsmÕte ved fremstilling derav
ATE451462T1 (de)	2009-12-15	Klonierung und expression von htlv-iii-dns
ATE233816T1 (de)	2003-03-15	Gereinigtes thermostabiles nukleinsäure- polymeraseenzym aus thermotoga maritima
FI925460A0 (fi)	1992-11-30	Protein d - ett igd-bindande protein av pfeiffers influensaprotein
FI885679A0 (fi)	1988-12-07	Samuttryckning i eukariotiska celler.
BG101408A (bg)	1997-12-30	Аналози на кератиноцитния растежен фактор
DE69333346T2 (de)	2004-10-07	Neuartiges p- selectin ligandenprotein
EP0263608A3 (de)	1989-06-14	Antikoagulantes und antimetastatisches Protein
CA2006087A1 (en)	1990-06-23	Polypeptides isolated from the venom of the spider hololena curta
Cretin et al.	1990	Complete cDNA sequence of sorghum phosphoenolpyruvate carboxylase involved in C4 photosynthesis
ATE82985T1 (de)	1992-12-15	Strukturelles phosphoprotein (pp 150) des menschlichen cytomegalovirus, seine herstellung und verwendung.
ATE275195T1 (de)	2004-09-15	Saccharose-stoffwechsel-mutanten
ATE72458T1 (de)	1992-02-15	Zugeordnete ribosomen und ihre verwendung zur herstellung von proteinen aus zellkulturen.
Takama et al.	1980	Purification and some properties of 6-phosphoglucose isomerase from Bacillus caldotenax
EP0285361A3 (de)	1989-11-02	Reinigung von Apase-1 und Wiedererlangung des Nematodenresistenzgens
FI872031A7 (fi)	1987-11-09	Streptokinaasin tuottaminen DNA-tekniikalla saadulla hiivalla.
EP0211321A3 (de)	1988-03-23	Aminosäurezusammensetzung, Verfahren zu deren Herstellung und diese enthaltende medizinische Zusammensetzung
EP0322084A3 (de)	1990-05-16	Tumorzellenhemmender Faktor
EP0293180A3 (de)	1990-01-24	Interleukin-2 von Vögeln
ATE292678T1 (de)	2005-04-15	Klonierung und rekombinante herstellung von polistinae venom-enzymen, beispielsweise phospholipase und hyaluronidase, und immunologische therapien davon abgeleitet
KR980002265A (ko)	1998-03-30	신규한 플라스미드 pKLE와 이를 이용한 리파제의 대량생산방법
KR970009339B1 (en)	1997-06-10	Tpa from scolopendra subepinpes multilans and its purification method