ATE118758T1 - Derivate von endogenen mediatoren, ihre salze, verfahren zur herstellung, anwendungen und zusammensetzungen, die diese enthalten. - Google Patents

Derivate von endogenen mediatoren, ihre salze, verfahren zur herstellung, anwendungen und zusammensetzungen, die diese enthalten.

Info

Publication number
ATE118758T1
ATE118758T1 AT91430009T AT91430009T ATE118758T1 AT E118758 T1 ATE118758 T1 AT E118758T1 AT 91430009 T AT91430009 T AT 91430009T AT 91430009 T AT91430009 T AT 91430009T AT E118758 T1 ATE118758 T1 AT E118758T1
Authority
AT
Austria
Prior art keywords
preparation
derivatives
salts
endogene
mediators
Prior art date
Application number
AT91430009T
Other languages
English (en)
Inventor
Jacques Chauveau
Michel Delaage
Anne Morel
Louis Segu
Original Assignee
Immunotech Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR9006292A external-priority patent/FR2662082B1/fr
Priority claimed from FR9101292A external-priority patent/FR2671971B1/fr
Application filed by Immunotech Sa filed Critical Immunotech Sa
Application granted granted Critical
Publication of ATE118758T1 publication Critical patent/ATE118758T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/34—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • C07C229/36—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings with at least one amino group and one carboxyl group bound to the same carbon atom of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C07D209/16—Tryptamines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • G01N33/78—Thyroid gland hormones, e.g. T3, T4, TBH, TBG or their receptors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Endocrinology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicinal Preparation (AREA)
AT91430009T 1990-05-15 1991-05-13 Derivate von endogenen mediatoren, ihre salze, verfahren zur herstellung, anwendungen und zusammensetzungen, die diese enthalten. ATE118758T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9006292A FR2662082B1 (fr) 1990-05-15 1990-05-15 Nouveaux derives de mediateurs endogenes, leurs sels, procede de preparation et applications.
FR9101292A FR2671971B1 (fr) 1991-01-30 1991-01-30 Nouveaux derives de la serotonine, application a titre de medicament et compositions les renfermant.

Publications (1)

Publication Number Publication Date
ATE118758T1 true ATE118758T1 (de) 1995-03-15

Family

ID=26228029

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91430009T ATE118758T1 (de) 1990-05-15 1991-05-13 Derivate von endogenen mediatoren, ihre salze, verfahren zur herstellung, anwendungen und zusammensetzungen, die diese enthalten.

Country Status (12)

Country Link
US (1) US5298491A (de)
EP (1) EP0457701B1 (de)
JP (1) JP2968623B2 (de)
KR (1) KR0138750B1 (de)
AT (1) ATE118758T1 (de)
AU (1) AU650265B2 (de)
CA (1) CA2042295A1 (de)
DE (1) DE69107512T2 (de)
DK (1) DK0457701T3 (de)
ES (1) ES2039313T3 (de)
IE (1) IE67888B1 (de)
NO (1) NO308663B1 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW288010B (de) * 1992-03-05 1996-10-11 Pfizer
EP0635015B1 (de) * 1992-04-10 1997-01-29 Pfizer Inc. Acylaminoindolderivate als 5-ht1 agonisten
TW251284B (de) * 1992-11-02 1995-07-11 Pfizer
FR2699918B1 (fr) * 1992-12-30 1995-03-17 Pf Medicament Ligands sélectifs des récepteurs 5HY1D-5HT1B dérivés d'indole-pipérazine utiles comme médicaments.
EP0703923B1 (de) * 1993-06-18 1998-10-07 Nycomed Imaging As Faktor vii-peptide
JP2000516210A (ja) 1996-07-12 2000-12-05 ロイコサイト，インコーポレーテッド ケモカインレセプターアンタゴニストとその使用方法
FR2773489B1 (fr) * 1998-01-15 2001-03-23 Immunotech Sa Nouvelle composition destinee a la voie oromuqueuse notamment pernasale
KR100596641B1 (ko) * 1998-12-11 2006-10-04 이승진 진단용 공중합성 미셀 및 그의 제조방법
US7163918B2 (en) * 2000-08-22 2007-01-16 New River Pharmaceuticals Inc. Iodothyronine compositions
US8394813B2 (en) 2000-11-14 2013-03-12 Shire Llc Active agent delivery systems and methods for protecting and administering active agents
US20060014697A1 (en) * 2001-08-22 2006-01-19 Travis Mickle Pharmaceutical compositions for prevention of overdose or abuse
BR0312175A (pt) 2002-06-21 2005-04-05 Suven Life Sciences Ltd Composto, composição farmacêutica, uso de um composto, método para o tratamento e método para reduzir a morbidez e a mortalidade associadas com o excesso de peso
ES2297216T3 (es) 2002-06-21 2008-05-01 Suven Life Sciences Limited Indoles tetraciclicos arilsulfonil que tienen afinidad con el receptor de la serotonina.
US7507835B2 (en) 2002-11-28 2009-03-24 Suven Life Sciences Ltd. N-arylsulfonyl-3-aminoalkoxyindoles
ATE401307T1 (de) 2002-11-28 2008-08-15 Suven Life Sciences Ltd N-arylsulfonyl-2-substituierte indole mit affinität zum serotonin rezeptor, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzungen
JP4571507B2 (ja) 2002-12-18 2010-10-27 スベン ライフ サイエンシズ リミティド セロトニン受容体親和性を有する四環系３−置換インドール

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2703325A (en) * 1951-12-06 1955-03-01 Upjohn Co Preparation of 5-benzyloxytryptamines
US3182071A (en) * 1961-06-27 1965-05-04 Warner Lambert Pharmaceutical Acylated indole derivatives
US3686213A (en) * 1970-08-28 1972-08-22 American Cyanamid Co Substituted aminoethyl indoles
US4046636A (en) * 1974-06-20 1977-09-06 Syva Company Diazepam enzyme conjugates
US3878187A (en) * 1972-09-11 1975-04-15 Syva Co Polypeptide derivatives of amphetamine and analogs for immunoassays
US4040907A (en) * 1974-06-20 1977-08-09 Syva Company Iodothyronine enzyme conjugates
DE2737802A1 (de) * 1977-08-22 1979-03-08 Henning Berlin Gmbh Arzneimittel oder diagnostikum zur behandlung oder feststellung von schilddruesenfunktionsstoerungen und verfahren zu dessen herstellung
FR2437398A1 (fr) * 1978-06-20 1980-04-25 Commissariat Energie Atomique Compose iode utilisable comme traceur en radio-immunologie
ZA795239B (en) * 1978-10-12 1980-11-26 Glaxo Group Ltd Heterocyclic compounds
ZW19381A1 (en) * 1980-08-12 1983-03-09 Glaxo Group Ltd Heterocyclic compounds
US4426453A (en) * 1980-09-18 1984-01-17 Amersham International Limited Derivatives of iodothyronine compounds and their use in an assay for the free iodothyronine compounds
EP0099707B1 (de) * 1982-07-16 1986-12-10 Beecham Group Plc 2-Aminoethyläther-Derivate, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Zusammensetzungen
JPS60132935A (ja) * 1983-12-20 1985-07-16 Sumitomo Chem Co Ltd フエニルセリン誘導体及びその製造方法
FR2562671B1 (fr) * 1984-04-10 1986-07-25 Immunotech Sa Procede pour le dosage immunologique des monoamines
EP0225726B1 (de) * 1985-11-08 1991-04-17 Glaxo Group Limited Indolderivate
GB8530507D0 (en) * 1985-12-11 1986-01-22 Glaxo Group Plc Chemical compounds
US4910193A (en) * 1985-12-16 1990-03-20 Sandoz Ltd. Treatment of gastrointestinal disorders
DE3628795A1 (de) * 1986-08-25 1988-03-03 Hoechst Ag Neue thyroninderivate
US5019586A (en) * 1987-04-14 1991-05-28 Glaxo Group Limited Ketone derivatives
GB8801306D0 (en) * 1988-01-21 1988-02-17 Ici Plc Chemical compounds
GB8802127D0 (en) * 1988-02-01 1988-03-02 Glaxo Group Ltd Chemical compounds
US4933324A (en) * 1988-02-26 1990-06-12 Shashoua Victor E Fatty acid-neuroactive drug conjugate as a prodrug
FR2671971B1 (fr) * 1991-01-30 1994-01-28 Immunotech Nouveaux derives de la serotonine, application a titre de medicament et compositions les renfermant.
FR2662082B1 (fr) * 1990-05-15 1994-12-23 Immunotech Sa Nouveaux derives de mediateurs endogenes, leurs sels, procede de preparation et applications.

Also Published As

Publication number Publication date
AU7704591A (en) 1991-11-21
NO308663B1 (no) 2000-10-09
KR910020034A (ko) 1991-12-19
EP0457701A1 (de) 1991-11-21
EP0457701B1 (de) 1995-02-22
US5298491A (en) 1994-03-29
NO911880L (no) 1991-11-18
JP2968623B2 (ja) 1999-10-25
AU650265B2 (en) 1994-06-16
IE911649A1 (en) 1991-11-20
NO911880D0 (no) 1991-05-14
DE69107512T2 (de) 1995-06-29
JPH04288044A (ja) 1992-10-13
DE69107512D1 (de) 1995-03-30
DK0457701T3 (da) 1996-02-05
IE67888B1 (en) 1996-05-01
ES2039313T3 (es) 1995-04-16
KR0138750B1 (ko) 1998-05-01
ES2039313T1 (es) 1993-10-01
CA2042295A1 (fr) 1991-11-16

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee