ATE119392T1 - Spezifischer produktinhibitor der retroviralen reversen transkriptase und seine verwendung als arzneimittel. - Google Patents

Spezifischer produktinhibitor der retroviralen reversen transkriptase und seine verwendung als arzneimittel.

Info

Publication number: ATE119392T1
Authority: AT; Austria
Prior art keywords: thio; reverse transcriptase; compound; product; inhibitor
Prior art date: 1989-06-02

Application number

AT90908553T

Other languages

English (en)

Inventor

Herbert A Blough

Miria Richetti

Henri Buc

Original Assignee

Herbert A Blough

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-06-02

Filing date

1990-06-01

Publication date

1995-03-15

1990-06-01 Application filed by Herbert A Blough filed Critical Herbert A Blough

1995-03-15 Application granted granted Critical

1995-03-15 Publication of ATE119392T1 publication Critical patent/ATE119392T1/de

Links

102100034343 Integrase Human genes 0.000 title abstract 2
108010092799 RNA-directed DNA polymerase Proteins 0.000 title abstract 2
239000003112 inhibitor Substances 0.000 title abstract 2
229940126601 medicinal product Drugs 0.000 title 1
230000001177 retroviral effect Effects 0.000 title 1
ABXYOVCSAGTJAC-JGWLITMVSA-N (2r,3s,4r,5r)-2,3,4,5,6-pentahydroxyhexanethial Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C=S ABXYOVCSAGTJAC-JGWLITMVSA-N 0.000 abstract 1
241000713730 Equine infectious anemia virus Species 0.000 abstract 1
208000031886 HIV Infections Diseases 0.000 abstract 1
241000714260 Human T-lymphotropic virus 1 Species 0.000 abstract 1
241000714259 Human T-lymphotropic virus 2 Species 0.000 abstract 1
241000713772 Human immunodeficiency virus 1 Species 0.000 abstract 1
241000713340 Human immunodeficiency virus 2 Species 0.000 abstract 1
241001465754 Metazoa Species 0.000 abstract 1
241000700605 Viruses Species 0.000 abstract 1
239000004480 active ingredient Substances 0.000 abstract 1
125000001931 aliphatic group Chemical group 0.000 abstract 1
229960001799 aurothioglucose Drugs 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
238000011321 prophylaxis Methods 0.000 abstract 1
239000000126 substance Substances 0.000 abstract 1
238000011282 treatment Methods 0.000 abstract 1
241001430294 unidentified retrovirus Species 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7004—Monosaccharides having only carbon, hydrogen and oxygen atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/28—Compounds containing heavy metals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H23/00—Compounds containing boron, silicon or a metal, e.g. chelates or vitamin B12
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
- C07H3/08—Deoxysugars; Unsaturated sugars; Osones

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Molecular Biology (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Biochemistry (AREA)
Genetics & Genomics (AREA)
Biotechnology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Communicable Diseases (AREA)
Virology (AREA)
Oncology (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Saccharide Compounds (AREA)
Medicines Containing Plant Substances (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

AT90908553T 1989-06-02 1990-06-01 Spezifischer produktinhibitor der retroviralen reversen transkriptase und seine verwendung als arzneimittel. ATE119392T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR8907356A FR2647792B1 (de)	1989-06-02	1989-06-02

Publications (1)

Publication Number	Publication Date
ATE119392T1 true ATE119392T1 (de)	1995-03-15

Family

ID=9382333

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT90908553T ATE119392T1 (de)	1989-06-02	1990-06-01	Spezifischer produktinhibitor der retroviralen reversen transkriptase und seine verwendung als arzneimittel.

Country Status (6)

Country	Link
EP (1)	EP0427843B1 (de)
JP (1)	JPH04501427A (de)
AT (1)	ATE119392T1 (de)
DE (1)	DE69017594D1 (de)
FR (1)	FR2647792B1 (de)
WO (1)	WO1990014825A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6177435B1 (en)	1992-05-13	2001-01-23	Glaxo Wellcome Inc.	Therapeutic combinations
US5603963A (en) *	1994-07-28	1997-02-18	University Of Cincinnati	Method for the treatment of retroviral diseases such as acquired immune deficiency syndrome utilizing (pseudo)halogen complexes of gold(1)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4315001A (en) *	1979-08-17	1982-02-09	Blough Herbert A	2-Deoxy glucose as an antiviral agent against herpes simplex
US4657763A (en) *	1985-09-03	1987-04-14	Michael Ebert	Combined chrysotherapeutic agents for autoimmune diseases

1989
- 1989-06-02 FR FR8907356A patent/FR2647792B1/fr not_active Expired - Lifetime
1990
- 1990-06-01 EP EP90908553A patent/EP0427843B1/de not_active Expired - Lifetime
- 1990-06-01 AT AT90908553T patent/ATE119392T1/de active
- 1990-06-01 DE DE69017594T patent/DE69017594D1/de not_active Expired - Lifetime
- 1990-06-01 WO PCT/FR1990/000387 patent/WO1990014825A1/fr not_active Ceased
- 1990-06-01 JP JP2508415A patent/JPH04501427A/ja active Pending

Also Published As

Publication number	Publication date
EP0427843B1 (de)	1995-03-08
FR2647792B1 (de)	1995-06-23
JPH04501427A (ja)	1992-03-12
EP0427843A1 (de)	1991-05-22
WO1990014825A1 (fr)	1990-12-13
FR2647792A1 (de)	1990-12-07
DE69017594D1 (de)	1995-04-13

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