ATE120743T1 - Pyridoindolderivate und verfahren zu ihrer herstellung. - Google Patents

Pyridoindolderivate und verfahren zu ihrer herstellung.

Info

Publication number: ATE120743T1
Authority: AT; Austria
Prior art keywords: hydrogen; production; lower alkyl; alkyl; hydroxy
Prior art date: 1988-09-27

Application number

AT89117498T

Other languages

English (en)

Inventor

Masayuki Kato

Kiyotaka Ito

Hisashi Takasugi

Original Assignee

Fujisawa Pharmaceutical Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-09-27

Filing date

1989-09-21

Publication date

1995-04-15

1988-09-27 Priority claimed from GB888822646A external-priority patent/GB8822646D0/en

1989-02-10 Priority claimed from GB898903044A external-priority patent/GB8903044D0/en

1989-09-21 Application filed by Fujisawa Pharmaceutical Co filed Critical Fujisawa Pharmaceutical Co

1995-04-15 Application granted granted Critical

1995-04-15 Publication of ATE120743T1 publication Critical patent/ATE120743T1/de

Links

IVCGJOSPVGENCT-UHFFFAOYSA-N 1h-pyrrolo[2,3-f]quinoline Chemical class N1=CC=CC2=C(NC=C3)C3=CC=C21 IVCGJOSPVGENCT-UHFFFAOYSA-N 0.000 title 1
125000000217 alkyl group Chemical group 0.000 abstract 4
229910052739 hydrogen Inorganic materials 0.000 abstract 4
239000001257 hydrogen Substances 0.000 abstract 4
125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 4
125000003342 alkenyl group Chemical group 0.000 abstract 2
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
125000004423 acyloxy group Chemical group 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
150000002367 halogens Chemical class 0.000 abstract 1
125000002883 imidazolyl group Chemical group 0.000 abstract 1
231100000252 nontoxic Toxicity 0.000 abstract 1
230000003000 nontoxic effect Effects 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
239000000546 pharmaceutical excipient Substances 0.000 abstract 1
125000004076 pyridyl group Chemical group 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
125000001424 substituent group Chemical group 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Anesthesiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Cephalosporin Compounds (AREA)
Saccharide Compounds (AREA)
Pyridine Compounds (AREA)

AT89117498T 1988-09-27 1989-09-21 Pyridoindolderivate und verfahren zu ihrer herstellung. ATE120743T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB888822646A GB8822646D0 (en)	1988-09-27	1988-09-27	Pyridoindole derivatives & processes for preparation thereof
GB898903044A GB8903044D0 (en)	1989-02-10	1989-02-10	Pyridoindole derivatives and processes for preparation thereof

Publications (1)

Publication Number	Publication Date
ATE120743T1 true ATE120743T1 (de)	1995-04-15

Family

ID=26294446

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT89117498T ATE120743T1 (de)	1988-09-27	1989-09-21	Pyridoindolderivate und verfahren zu ihrer herstellung.

Country Status (20)

Country	Link
US (1)	US5141945A (de)
EP (1)	EP0361317B1 (de)
JP (1)	JPH02117675A (de)
KR (1)	KR0143999B1 (de)
CN (1)	CN1024552C (de)
AT (1)	ATE120743T1 (de)
AU (1)	AU627221B2 (de)
CA (1)	CA1338474C (de)
DE (1)	DE68922053T2 (de)
DK (1)	DK170168B1 (de)
ES (1)	ES2070154T3 (de)
FI (1)	FI92200C (de)
GR (1)	GR3015713T3 (de)
HK (1)	HK102096A (de)
HU (2)	HU206209B (de)
IE (1)	IE67350B1 (de)
IL (1)	IL91756A (de)
NO (1)	NO172541C (de)
PT (1)	PT91795B (de)
RU (1)	RU2001915C1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5290785A (en) *	1988-09-27	1994-03-01	Fujisawa Pharmaceutical Co., Ltd.	Therapeutic agent for ischemic diseases
US5173493A (en) *	1988-09-27	1992-12-22	Fujisawa Pharmaceutical Company, Ltd.	Pyridoindole derivatives and processes for preparation thereof
GB9214184D0 (en) *	1992-07-03	1992-08-12	Smithkline Beecham Plc	Pharmaceuticals
EP0688216A1 (de) *	1993-03-08	1995-12-27	Fujisawa Pharmaceutical Co., Ltd.	Medikament zur behandlung und prävention von zerebrovaskulären erkrankungen
ATE212860T1 (de) *	1994-09-19	2002-02-15	Fujisawa Pharmaceutical Co	Eine neuartige medizinische verwendung eines 5ht 3-antagonisten
AU7000696A (en) *	1995-09-22	1997-04-09	Fujisawa Pharmaceutical Co., Ltd.	Novel processes for producing pyridoindole derivatives
FR2869316B1 (fr) *	2004-04-21	2006-06-02	Sanofi Synthelabo	Derives de pyridoindolone substitues en -6, leur preparation et leur application en therapeutique.
AU2018258117A1 (en)	2017-04-24	2019-12-12	Chase Therapeutics Corporation	Compositions and method for treating depression
CN116003407B (zh) *	2022-12-27	2025-04-01	株洲千金药业股份有限公司	一种大规模生产唑吡坦的合成方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
PH22672A (en) *	1984-01-25	1988-11-14	Glaxo Group Ltd	Imidazolylmethyltetrahydrocarbazolone derivatives, composition and method of use thereof
GB8516083D0 (en) *	1985-06-25	1985-07-31	Glaxo Group Ltd	Heterocyclic compounds
GB8518743D0 (en) *	1985-07-24	1985-08-29	Glaxo Group Ltd	Heterocyclic compounds
GR871809B (en) *	1986-11-28	1988-03-07	Glaxo Group Ltd	Process for the preparation of tricyclic ketones

1989
- 1989-09-14 AU AU41406/89A patent/AU627221B2/en not_active Ceased
- 1989-09-19 IE IE299989A patent/IE67350B1/en not_active IP Right Cessation
- 1989-09-20 US US07/409,744 patent/US5141945A/en not_active Expired - Fee Related
- 1989-09-21 DE DE68922053T patent/DE68922053T2/de not_active Expired - Fee Related
- 1989-09-21 ES ES89117498T patent/ES2070154T3/es not_active Expired - Lifetime
- 1989-09-21 EP EP89117498A patent/EP0361317B1/de not_active Expired - Lifetime
- 1989-09-21 AT AT89117498T patent/ATE120743T1/de not_active IP Right Cessation
- 1989-09-24 IL IL91756A patent/IL91756A/xx not_active IP Right Cessation
- 1989-09-25 FI FI894506A patent/FI92200C/fi not_active IP Right Cessation
- 1989-09-25 CA CA000612855A patent/CA1338474C/en not_active Expired - Fee Related
- 1989-09-25 PT PT91795A patent/PT91795B/pt not_active IP Right Cessation
- 1989-09-26 CN CN89107692A patent/CN1024552C/zh not_active Expired - Fee Related
- 1989-09-26 RU SU894742106A patent/RU2001915C1/ru active
- 1989-09-26 NO NO893820A patent/NO172541C/no unknown
- 1989-09-26 HU HU895038A patent/HU206209B/hu not_active IP Right Cessation
- 1989-09-26 KR KR1019890013798A patent/KR0143999B1/ko not_active Expired - Fee Related
- 1989-09-26 DK DK474089A patent/DK170168B1/da not_active IP Right Cessation
- 1989-09-27 JP JP1252986A patent/JPH02117675A/ja active Granted
1995
- 1995-04-06 GR GR950400770T patent/GR3015713T3/el unknown
- 1995-06-22 HU HU95P/P00372P patent/HU211139A9/hu unknown
1996
- 1996-06-13 HK HK102096A patent/HK102096A/en not_active IP Right Cessation

Also Published As

Publication number	Publication date
CN1041594A (zh)	1990-04-25
DK474089A (da)	1990-03-28
FI92200C (fi)	1994-10-10
HU206209B (en)	1992-09-28
IE892999L (en)	1990-03-27
NO893820L (no)	1990-03-28
JPH054392B2 (de)	1993-01-19
GR3015713T3 (en)	1995-07-31
IL91756A0 (en)	1990-06-10
KR900004733A (ko)	1990-04-12
PT91795B (pt)	1995-05-31
RU2001915C1 (ru)	1993-10-30
DE68922053D1 (de)	1995-05-11
HUT51623A (en)	1990-05-28
DK170168B1 (da)	1995-06-06
IE67350B1 (en)	1996-03-20
DK474089D0 (da)	1989-09-26
NO172541C (no)	1993-08-04
EP0361317A2 (de)	1990-04-04
IL91756A (en)	1993-07-08
PT91795A (pt)	1990-03-30
US5141945A (en)	1992-08-25
FI894506L (fi)	1990-03-28
HU211139A9 (en)	1995-10-30
AU627221B2 (en)	1992-08-20
HK102096A (en)	1996-06-21
CN1024552C (zh)	1994-05-18
NO893820D0 (no)	1989-09-26
CA1338474C (en)	1996-07-23
NO172541B (no)	1993-04-26
DE68922053T2 (de)	1995-08-10
FI894506A0 (fi)	1989-09-25
JPH02117675A (ja)	1990-05-02
EP0361317B1 (de)	1995-04-05
AU4140689A (en)	1990-04-05
ES2070154T3 (es)	1995-06-01
KR0143999B1 (ko)	1998-07-15
EP0361317A3 (de)	1991-07-24
FI92200B (fi)	1994-06-30

Legal Events

Date	Code	Title	Description
1995-11-15	UEP	Publication of translation of european patent specification
2000-06-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
AU624405B2 (en)	1992-06-11	Heterocyclic bisphosphonic acid derivatives
AU589427B2 (en)	1989-10-12	Pyridonecarboxylic acid derivatives and process for their preparation
HUT53368A (en)	1990-10-28	Process for producing pyrazolo-pyridine derivatives and pharmaceutical compositions containing them
HUT49612A (en)	1989-10-30	Process for producing new 3-alkenyl-1-azabicyclo/3.2.0/ hept-2-ene-2-carboxylic acid derivatives and pharmaceutical compositions comprising same
AU6128590A (en)	1991-02-28	Novel compounds
DE69021755D1 (de)	1995-09-28	Benzopyranderivate und Verfahren zu ihrer Herstellung.
FR2669336B1 (fr)	1993-01-22	Nouveaux derives d'oxazolo pyridines, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent.
DE68922053D1 (de)	1995-05-11	Pyridoindolderivate und Verfahren zu ihrer Herstellung.
IL86080A (en)	1992-07-15	Substituted alkoxy-2-alkyl-indan and 1,2,3,4-tetrahydro-naphthol,process for the preparation thereof and pharmaceutical compositions comprising the same
AU655869B2 (en)	1995-01-12	An amphoteric tricyclic compound
ATE30724T1 (de)	1987-11-15	Cephalosporinderivate, verfahren zu ihrer herstellung und pharmazeutische zusammensetzungen die sie enthalten.
DE68905363D1 (de)	1993-04-22	Heterotetracyclische laktamderivate, verfahren zu ihrer herstellung und pharmazeutische zubereitungen, die sie enthalten.
HUT62855A (en)	1993-06-28	Process for producing glycerol derivatives and pharmaceutical compositions comprising same
HUT45059A (en)	1988-05-30	Process for producing abeoergoline derivatives
ATE131480T1 (de)	1995-12-15	Pyrimidoindolderivate und verfahren zu ihrer herstellung
IL87107A0 (en)	1988-12-30	Naphthothiazepine derivatives,their preparation and pharmaceutical compositions containing them
ATE29133T1 (de)	1987-09-15	Troponon-derivate, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzung.