IL91756A - 8,9-dihydro-7-substituted- pyrido (1,2-a) indol-6 (7h)-one derivatives, processes for the preparation thereof and pharmaceutical compositions containing the same - Google Patents

8,9-dihydro-7-substituted- pyrido (1,2-a) indol-6 (7h)-one derivatives, processes for the preparation thereof and pharmaceutical compositions containing the same

Info

Publication number: IL91756A
Authority: IL; Israel
Prior art keywords: processes; preparation; pharmaceutical compositions; pyrido; indol
Prior art date: 1988-09-27

Application number

IL91756A

Other languages

English (en)

Other versions

IL91756A0 (en

Original Assignee

Fujisawa Pharmaceutical Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-09-27

Filing date

1989-09-24

Publication date

1993-07-08

1988-09-27 Priority claimed from GB888822646A external-priority patent/GB8822646D0/en

1989-02-10 Priority claimed from GB898903044A external-priority patent/GB8903044D0/en

1989-09-24 Application filed by Fujisawa Pharmaceutical Co filed Critical Fujisawa Pharmaceutical Co

1990-06-10 Publication of IL91756A0 publication Critical patent/IL91756A0/xx

1993-07-08 Publication of IL91756A publication Critical patent/IL91756A/xx

Links

239000008194 pharmaceutical composition Substances 0.000 title abstract 2
-1 8,9-dihydro-7-substituted- pyrido (1,2-a) indol-6 (7h)-one Chemical class 0.000 title 1
125000000217 alkyl group Chemical group 0.000 abstract 4
229910052739 hydrogen Inorganic materials 0.000 abstract 4
239000001257 hydrogen Substances 0.000 abstract 4
125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 4
125000003342 alkenyl group Chemical group 0.000 abstract 2
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
125000004423 acyloxy group Chemical group 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
150000002367 halogens Chemical class 0.000 abstract 1
125000002883 imidazolyl group Chemical group 0.000 abstract 1
231100000252 nontoxic Toxicity 0.000 abstract 1
230000003000 nontoxic effect Effects 0.000 abstract 1
239000000546 pharmaceutical excipient Substances 0.000 abstract 1
125000004076 pyridyl group Chemical group 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
125000001424 substituent group Chemical group 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Anesthesiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Cephalosporin Compounds (AREA)
Saccharide Compounds (AREA)
Pyridine Compounds (AREA)

IL91756A 1988-09-27 1989-09-24 8,9-dihydro-7-substituted- pyrido (1,2-a) indol-6 (7h)-one derivatives, processes for the preparation thereof and pharmaceutical compositions containing the same IL91756A (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB888822646A GB8822646D0 (en)	1988-09-27	1988-09-27	Pyridoindole derivatives & processes for preparation thereof
GB898903044A GB8903044D0 (en)	1989-02-10	1989-02-10	Pyridoindole derivatives and processes for preparation thereof

Publications (2)

Publication Number	Publication Date
IL91756A0 IL91756A0 (en)	1990-06-10
IL91756A true IL91756A (en)	1993-07-08

Family

ID=26294446

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL91756A IL91756A (en)	1988-09-27	1989-09-24	8,9-dihydro-7-substituted- pyrido (1,2-a) indol-6 (7h)-one derivatives, processes for the preparation thereof and pharmaceutical compositions containing the same

Country Status (20)

Country	Link
US (1)	US5141945A (de)
EP (1)	EP0361317B1 (de)
JP (1)	JPH02117675A (de)
KR (1)	KR0143999B1 (de)
CN (1)	CN1024552C (de)
AT (1)	ATE120743T1 (de)
AU (1)	AU627221B2 (de)
CA (1)	CA1338474C (de)
DE (1)	DE68922053T2 (de)
DK (1)	DK170168B1 (de)
ES (1)	ES2070154T3 (de)
FI (1)	FI92200C (de)
GR (1)	GR3015713T3 (de)
HK (1)	HK102096A (de)
HU (2)	HU206209B (de)
IE (1)	IE67350B1 (de)
IL (1)	IL91756A (de)
NO (1)	NO172541C (de)
PT (1)	PT91795B (de)
RU (1)	RU2001915C1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5290785A (en) *	1988-09-27	1994-03-01	Fujisawa Pharmaceutical Co., Ltd.	Therapeutic agent for ischemic diseases
US5173493A (en) *	1988-09-27	1992-12-22	Fujisawa Pharmaceutical Company, Ltd.	Pyridoindole derivatives and processes for preparation thereof
GB9214184D0 (en) *	1992-07-03	1992-08-12	Smithkline Beecham Plc	Pharmaceuticals
EP0688216A1 (de) *	1993-03-08	1995-12-27	Fujisawa Pharmaceutical Co., Ltd.	Medikament zur behandlung und prävention von zerebrovaskulären erkrankungen
ATE212860T1 (de) *	1994-09-19	2002-02-15	Fujisawa Pharmaceutical Co	Eine neuartige medizinische verwendung eines 5ht 3-antagonisten
AU7000696A (en) *	1995-09-22	1997-04-09	Fujisawa Pharmaceutical Co., Ltd.	Novel processes for producing pyridoindole derivatives
FR2869316B1 (fr) *	2004-04-21	2006-06-02	Sanofi Synthelabo	Derives de pyridoindolone substitues en -6, leur preparation et leur application en therapeutique.
AU2018258117A1 (en)	2017-04-24	2019-12-12	Chase Therapeutics Corporation	Compositions and method for treating depression
CN116003407B (zh) *	2022-12-27	2025-04-01	株洲千金药业股份有限公司	一种大规模生产唑吡坦的合成方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
PH22672A (en) *	1984-01-25	1988-11-14	Glaxo Group Ltd	Imidazolylmethyltetrahydrocarbazolone derivatives, composition and method of use thereof
GB8516083D0 (en) *	1985-06-25	1985-07-31	Glaxo Group Ltd	Heterocyclic compounds
GB8518743D0 (en) *	1985-07-24	1985-08-29	Glaxo Group Ltd	Heterocyclic compounds
GR871809B (en) *	1986-11-28	1988-03-07	Glaxo Group Ltd	Process for the preparation of tricyclic ketones

1989
- 1989-09-14 AU AU41406/89A patent/AU627221B2/en not_active Ceased
- 1989-09-19 IE IE299989A patent/IE67350B1/en not_active IP Right Cessation
- 1989-09-20 US US07/409,744 patent/US5141945A/en not_active Expired - Fee Related
- 1989-09-21 DE DE68922053T patent/DE68922053T2/de not_active Expired - Fee Related
- 1989-09-21 ES ES89117498T patent/ES2070154T3/es not_active Expired - Lifetime
- 1989-09-21 EP EP89117498A patent/EP0361317B1/de not_active Expired - Lifetime
- 1989-09-21 AT AT89117498T patent/ATE120743T1/de not_active IP Right Cessation
- 1989-09-24 IL IL91756A patent/IL91756A/xx not_active IP Right Cessation
- 1989-09-25 FI FI894506A patent/FI92200C/fi not_active IP Right Cessation
- 1989-09-25 CA CA000612855A patent/CA1338474C/en not_active Expired - Fee Related
- 1989-09-25 PT PT91795A patent/PT91795B/pt not_active IP Right Cessation
- 1989-09-26 CN CN89107692A patent/CN1024552C/zh not_active Expired - Fee Related
- 1989-09-26 RU SU894742106A patent/RU2001915C1/ru active
- 1989-09-26 NO NO893820A patent/NO172541C/no unknown
- 1989-09-26 HU HU895038A patent/HU206209B/hu not_active IP Right Cessation
- 1989-09-26 KR KR1019890013798A patent/KR0143999B1/ko not_active Expired - Fee Related
- 1989-09-26 DK DK474089A patent/DK170168B1/da not_active IP Right Cessation
- 1989-09-27 JP JP1252986A patent/JPH02117675A/ja active Granted
1995
- 1995-04-06 GR GR950400770T patent/GR3015713T3/el unknown
- 1995-06-22 HU HU95P/P00372P patent/HU211139A9/hu unknown
1996
- 1996-06-13 HK HK102096A patent/HK102096A/en not_active IP Right Cessation

Also Published As

Publication number	Publication date
CN1041594A (zh)	1990-04-25
DK474089A (da)	1990-03-28
FI92200C (fi)	1994-10-10
HU206209B (en)	1992-09-28
IE892999L (en)	1990-03-27
NO893820L (no)	1990-03-28
JPH054392B2 (de)	1993-01-19
GR3015713T3 (en)	1995-07-31
IL91756A0 (en)	1990-06-10
KR900004733A (ko)	1990-04-12
PT91795B (pt)	1995-05-31
RU2001915C1 (ru)	1993-10-30
DE68922053D1 (de)	1995-05-11
HUT51623A (en)	1990-05-28
DK170168B1 (da)	1995-06-06
IE67350B1 (en)	1996-03-20
DK474089D0 (da)	1989-09-26
NO172541C (no)	1993-08-04
EP0361317A2 (de)	1990-04-04
PT91795A (pt)	1990-03-30
US5141945A (en)	1992-08-25
FI894506L (fi)	1990-03-28
HU211139A9 (en)	1995-10-30
AU627221B2 (en)	1992-08-20
HK102096A (en)	1996-06-21
CN1024552C (zh)	1994-05-18
NO893820D0 (no)	1989-09-26
CA1338474C (en)	1996-07-23
NO172541B (no)	1993-04-26
DE68922053T2 (de)	1995-08-10
FI894506A0 (fi)	1989-09-25
JPH02117675A (ja)	1990-05-02
EP0361317B1 (de)	1995-04-05
AU4140689A (en)	1990-04-05
ES2070154T3 (es)	1995-06-01
KR0143999B1 (ko)	1998-07-15
ATE120743T1 (de)	1995-04-15
EP0361317A3 (de)	1991-07-24
FI92200B (fi)	1994-06-30

Legal Events

Date	Code	Title	Description
2000-12-06	RH	Patent void
2006-02-21	HC	Change of name of proprietor(s)

Publication	Publication Date	Title
AU624405B2 (en)	1992-06-11	Heterocyclic bisphosphonic acid derivatives
HUT58735A (en)	1992-03-30	Process for producing pyrazolo-pyridine derivatives
HUT66302A (en)	1994-11-28	Imidazo[1,2-a]pyridine derivatives, pharmaceutical compositions containing them and process for preparing them
HUT49612A (en)	1989-10-30	Process for producing new 3-alkenyl-1-azabicyclo/3.2.0/ hept-2-ene-2-carboxylic acid derivatives and pharmaceutical compositions comprising same
GR3015713T3 (en)	1995-07-31	Pyridoindole derivatives and processes for preparation thereof.
IE891261L (en)	1989-10-20	Heterotetracyclic lactam derivatives
HUT52044A (en)	1990-06-28	Process for producing pyrrolidine derivatives
PT85378A (en)	1987-08-01	Process for the preparation of new tetracyclic indole derivatives and of pharmaceutical compositions containing the same
ES2087173T3 (es)	1996-07-16	Uso de derivados de piridoindol en el tratamiento de enfermedades isquemicas.
DE3465594D1 (en)	1987-10-01	Tropone derivatives, processes for preparation thereof and pharmaceutical composition comprising the same
EP0420086A3 (en)	1991-11-06	Pyrimidoindole derivatives and processes for preparation thereof