ATE121301T1 - Mikrokristalle, die eine aktive substanz mit phospholipidischer affinität enthalten und mindestens ein phospholipid, verfahren zur herstellung. - Google Patents

Mikrokristalle, die eine aktive substanz mit phospholipidischer affinität enthalten und mindestens ein phospholipid, verfahren zur herstellung.

Info

Publication number
ATE121301T1
ATE121301T1 AT87402747T AT87402747T ATE121301T1 AT E121301 T1 ATE121301 T1 AT E121301T1 AT 87402747 T AT87402747 T AT 87402747T AT 87402747 T AT87402747 T AT 87402747T AT E121301 T1 ATE121301 T1 AT E121301T1
Authority
AT
Austria
Prior art keywords
phospholipid
affinity
phospholipidic
producing
active substance
Prior art date
Application number
AT87402747T
Other languages
English (en)
Inventor
Roger Baurain
Andre Trouet
Original Assignee
Liposome Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR8617116A external-priority patent/FR2607719B1/fr
Priority claimed from FR8702137A external-priority patent/FR2611138B2/fr
Priority claimed from FR8712424A external-priority patent/FR2620028B2/fr
Application filed by Liposome Co Inc filed Critical Liposome Co Inc
Application granted granted Critical
Publication of ATE121301T1 publication Critical patent/ATE121301T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/5123—Organic compounds, e.g. fats, sugars
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1277—Preparation processes; Proliposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Nanotechnology (AREA)
  • Optics & Photonics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Pulmonology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Furan Compounds (AREA)
  • Peptides Or Proteins (AREA)
AT87402747T 1986-12-05 1987-12-03 Mikrokristalle, die eine aktive substanz mit phospholipidischer affinität enthalten und mindestens ein phospholipid, verfahren zur herstellung. ATE121301T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR8617116A FR2607719B1 (fr) 1986-12-05 1986-12-05 Microcristaux comportant a titre de substance active des ginkgolides et compositions pharmaceutiques les contenant
FR8702137A FR2611138B2 (fr) 1986-12-05 1987-02-19 Microcristaux comportant une substance active presentant une affinite pour les phospholipides
FR8712424A FR2620028B2 (fr) 1986-12-05 1987-09-08 Procede de preparation de microcristaux comportant a titre de substance active, notamment de l'amphotericine b, microcristaux obtenus et composition pharmaceutique en comprenant

Publications (1)

Publication Number Publication Date
ATE121301T1 true ATE121301T1 (de) 1995-05-15

Family

ID=27251413

Family Applications (1)

Application Number Title Priority Date Filing Date
AT87402747T ATE121301T1 (de) 1986-12-05 1987-12-03 Mikrokristalle, die eine aktive substanz mit phospholipidischer affinität enthalten und mindestens ein phospholipid, verfahren zur herstellung.

Country Status (8)

Country Link
US (1) US4973465A (de)
EP (1) EP0270460B1 (de)
JP (1) JP2852421B2 (de)
AT (1) ATE121301T1 (de)
CA (1) CA1338736C (de)
DE (1) DE3751258T2 (de)
ES (1) ES2070827T3 (de)
HK (1) HK1007502A1 (de)

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Also Published As

Publication number Publication date
EP0270460B1 (de) 1995-04-19
EP0270460A2 (de) 1988-06-08
ES2070827T3 (es) 1995-06-16
JP2852421B2 (ja) 1999-02-03
CA1338736C (fr) 1996-11-26
EP0270460A3 (en) 1990-09-05
DE3751258D1 (de) 1995-05-24
HK1007502A1 (en) 1999-04-16
DE3751258T2 (de) 1995-09-07
JPS63208515A (ja) 1988-08-30
US4973465A (en) 1990-11-27

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EELA Cancelled due to lapse of time