ATE140622T1 - Fettemulsion - Google Patents
FettemulsionInfo
- Publication number
- ATE140622T1 ATE140622T1 AT90917270T AT90917270T ATE140622T1 AT E140622 T1 ATE140622 T1 AT E140622T1 AT 90917270 T AT90917270 T AT 90917270T AT 90917270 T AT90917270 T AT 90917270T AT E140622 T1 ATE140622 T1 AT E140622T1
- Authority
- AT
- Austria
- Prior art keywords
- emulsion
- polyene antifungal
- simple lipid
- fat emulsion
- antifungal
- Prior art date
Links
- 239000002960 lipid emulsion Substances 0.000 title abstract 2
- 230000000843 anti-fungal effect Effects 0.000 abstract 4
- 229940121375 antifungal agent Drugs 0.000 abstract 3
- 150000004291 polyenes Chemical class 0.000 abstract 3
- 239000003242 anti bacterial agent Substances 0.000 abstract 2
- 229940088710 antibiotic agent Drugs 0.000 abstract 2
- 229940079593 drug Drugs 0.000 abstract 2
- 239000003814 drug Substances 0.000 abstract 2
- 239000000839 emulsion Substances 0.000 abstract 2
- 150000002632 lipids Chemical class 0.000 abstract 2
- APKFDSVGJQXUKY-KKGHZKTASA-N Amphotericin-B Natural products O[C@H]1[C@@H](N)[C@H](O)[C@@H](C)O[C@H]1O[C@H]1C=CC=CC=CC=CC=CC=CC=C[C@H](C)[C@@H](O)[C@@H](C)[C@H](C)OC(=O)C[C@H](O)C[C@H](O)CC[C@@H](O)[C@H](O)C[C@H](O)C[C@](O)(C[C@H](O)[C@H]2C(O)=O)O[C@H]2C1 APKFDSVGJQXUKY-KKGHZKTASA-N 0.000 abstract 1
- 206010029155 Nephropathy toxic Diseases 0.000 abstract 1
- 230000002411 adverse Effects 0.000 abstract 1
- APKFDSVGJQXUKY-INPOYWNPSA-N amphotericin B Chemical compound O[C@H]1[C@@H](N)[C@H](O)[C@@H](C)O[C@H]1O[C@H]1/C=C/C=C/C=C/C=C/C=C/C=C/C=C/[C@H](C)[C@@H](O)[C@@H](C)[C@H](C)OC(=O)C[C@H](O)C[C@H](O)CC[C@@H](O)[C@H](O)C[C@H](O)C[C@](O)(C[C@H](O)[C@H]2C(O)=O)O[C@H]2C1 APKFDSVGJQXUKY-INPOYWNPSA-N 0.000 abstract 1
- 229960003942 amphotericin b Drugs 0.000 abstract 1
- 230000003115 biocidal effect Effects 0.000 abstract 1
- 230000002949 hemolytic effect Effects 0.000 abstract 1
- 239000004615 ingredient Substances 0.000 abstract 1
- 239000004530 micro-emulsion Substances 0.000 abstract 1
- 230000005012 migration Effects 0.000 abstract 1
- 238000013508 migration Methods 0.000 abstract 1
- 230000007694 nephrotoxicity Effects 0.000 abstract 1
- 231100000417 nephrotoxicity Toxicity 0.000 abstract 1
- 239000002245 particle Substances 0.000 abstract 1
- 230000000144 pharmacologic effect Effects 0.000 abstract 1
- 150000003904 phospholipids Chemical class 0.000 abstract 1
- 231100000004 severe toxicity Toxicity 0.000 abstract 1
- 231100000419 toxicity Toxicity 0.000 abstract 1
- 230000001988 toxicity Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Molecular Biology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Dispersion Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Edible Oils And Fats (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP30862289 | 1989-11-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE140622T1 true ATE140622T1 (de) | 1996-08-15 |
Family
ID=17983265
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT90917270T ATE140622T1 (de) | 1989-11-27 | 1990-11-26 | Fettemulsion |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP0598116B1 (de) |
| JP (1) | JP2653245B2 (de) |
| KR (1) | KR0151704B1 (de) |
| AT (1) | ATE140622T1 (de) |
| CA (1) | CA2069635C (de) |
| DE (1) | DE69027941T2 (de) |
| ES (1) | ES2090147T3 (de) |
| WO (1) | WO1991007973A1 (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6436425B1 (en) | 1988-11-16 | 2002-08-20 | Mdv Technologies, Inc. | Method and non-gelling composition for inhibiting post-surgical adhesions |
| US5346703A (en) | 1990-08-07 | 1994-09-13 | Mediventures, Inc. | Body cavity drug delivery with thermo-irreversible polyoxyalkylene and ionic polysaccharide gels |
| US5318780A (en) * | 1991-10-30 | 1994-06-07 | Mediventures Inc. | Medical uses of in situ formed gels |
| US5843470A (en) | 1995-10-06 | 1998-12-01 | Mdv Technologies, Inc. | Method and composition for inhibiting post-surgical adhesions |
| CA2316248A1 (en) * | 1997-12-23 | 1999-07-01 | Alliance Pharmaceutical Corp. | Methods and compositions for the delivery of pharmaceutical agents and/or the prevention of adhesions |
| DE19825856A1 (de) * | 1998-06-10 | 1999-12-16 | Labtec Gmbh | Topische Arzneimittelzubereitung |
| IT1301807B1 (it) * | 1998-06-25 | 2000-07-07 | Tiberio Bruzzese | Formulazioni farmaceutiche iniettabili di derivati della partricina. |
| GB2511028A (en) * | 2012-12-18 | 2014-08-27 | Univ Manchester Metropolitan | Nano emulsions, methods of forming the same and uses thereof |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS58222014A (ja) * | 1982-06-18 | 1983-12-23 | Taisho Pharmaceut Co Ltd | プロスタグランジンｅ↓１脂肪乳剤 |
| JPS59141518A (ja) * | 1983-02-03 | 1984-08-14 | Taisho Pharmaceut Co Ltd | プロスタグランジン脂肪乳剤 |
| JPS59216820A (ja) * | 1983-05-20 | 1984-12-06 | Taisho Pharmaceut Co Ltd | プロスタグランジン脂肪乳剤 |
| US4707470A (en) * | 1985-05-17 | 1987-11-17 | Smithkline Beckman Corporation | Polyene antibiotic emulsion formulation |
| JPS61291512A (ja) * | 1985-06-19 | 1986-12-22 | Kao Corp | 皮膚料 |
| IL78929A0 (en) * | 1985-07-29 | 1986-09-30 | Abbott Lab | Microemulsion compositions for parenteral administration |
| DE3625169A1 (de) * | 1986-07-25 | 1988-01-28 | Bayer Ag | Verwendung von haertbaren reaktionsmassen zur herstellung von datentraegern |
| IE60901B1 (en) * | 1986-08-21 | 1994-08-24 | Vestar Inc | Improved treatment of systemic fungal infections with phospholipid particles encapsulating polyene antifungal antibiotics |
| US4925678A (en) * | 1987-04-01 | 1990-05-15 | Ranney David F | Endothelial envelopment drug carriers |
| CA1338736C (fr) * | 1986-12-05 | 1996-11-26 | Roger Baurain | Microcristaux comportant une substance active presentant une affinite pour les phospholipides, et au moins un phospholipide, procede de preparation |
| GB8714652D0 (en) * | 1987-06-23 | 1987-07-29 | Davis S S | Drug emulsion |
| AU598958B2 (en) * | 1987-11-12 | 1990-07-05 | Vestar, Inc. | Improved amphotericin b liposome preparation |
-
1990
- 1990-11-26 AT AT90917270T patent/ATE140622T1/de not_active IP Right Cessation
- 1990-11-26 ES ES90917270T patent/ES2090147T3/es not_active Expired - Lifetime
- 1990-11-26 DE DE69027941T patent/DE69027941T2/de not_active Expired - Fee Related
- 1990-11-26 CA CA002069635A patent/CA2069635C/en not_active Expired - Fee Related
- 1990-11-26 WO PCT/JP1990/001531 patent/WO1991007973A1/ja not_active Ceased
- 1990-11-26 KR KR1019920701233A patent/KR0151704B1/ko not_active Expired - Fee Related
- 1990-11-26 JP JP3500269A patent/JP2653245B2/ja not_active Expired - Lifetime
- 1990-11-26 EP EP90917270A patent/EP0598116B1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP0598116A4 (de) | 1992-07-30 |
| CA2069635A1 (en) | 1991-05-28 |
| ES2090147T3 (es) | 1996-10-16 |
| CA2069635C (en) | 1998-05-05 |
| WO1991007973A1 (en) | 1991-06-13 |
| DE69027941T2 (de) | 1997-01-23 |
| KR0151704B1 (ko) | 1998-10-15 |
| DE69027941D1 (de) | 1996-08-29 |
| JP2653245B2 (ja) | 1997-09-17 |
| EP0598116B1 (de) | 1996-07-24 |
| KR920703070A (ko) | 1992-12-17 |
| EP0598116A1 (de) | 1994-05-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |