ATE121405T1 - Oxazolopyridinderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen. - Google Patents
Oxazolopyridinderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen.Info
- Publication number
- ATE121405T1 ATE121405T1 AT90402255T AT90402255T ATE121405T1 AT E121405 T1 ATE121405 T1 AT E121405T1 AT 90402255 T AT90402255 T AT 90402255T AT 90402255 T AT90402255 T AT 90402255T AT E121405 T1 ATE121405 T1 AT E121405T1
- Authority
- AT
- Austria
- Prior art keywords
- optionally substituted
- halogen atoms
- group
- lower alkyl
- production
- Prior art date
Links
- BFPLMTPHDFFMTG-UHFFFAOYSA-N [1,3]oxazolo[5,4-b]pyridine Chemical class C1=CN=C2OC=NC2=C1 BFPLMTPHDFFMTG-UHFFFAOYSA-N 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 239000000825 pharmaceutical preparation Substances 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- 125000005843 halogen group Chemical group 0.000 abstract 4
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 2
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000004104 aryloxy group Chemical group 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000001072 heteroaryl group Chemical group 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- -1 hydroxy, hydroxysulfonyloxy Chemical group 0.000 abstract 1
- 229940126601 medicinal product Drugs 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pain & Pain Management (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8910597A FR2650591B1 (fr) | 1989-08-07 | 1989-08-07 | Nouveaux derives d'oxazolo pyridines, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE121405T1 true ATE121405T1 (de) | 1995-05-15 |
Family
ID=9384526
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT90402255T ATE121405T1 (de) | 1989-08-07 | 1990-08-07 | Oxazolopyridinderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen. |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US5084456A (de) |
| EP (1) | EP0412899B1 (de) |
| JP (1) | JPH0699396B2 (de) |
| AT (1) | ATE121405T1 (de) |
| AU (1) | AU625886B2 (de) |
| CA (1) | CA2022732A1 (de) |
| DE (1) | DE69018730D1 (de) |
| FR (1) | FR2650591B1 (de) |
| IE (1) | IE902845A1 (de) |
| NZ (1) | NZ234789A (de) |
| OA (1) | OA09460A (de) |
| PT (1) | PT94929A (de) |
| ZA (1) | ZA906212B (de) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2663929A1 (fr) * | 1990-06-29 | 1992-01-03 | Adir | Nouveaux derives d'oxazolo pyridines, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
| US5242923A (en) * | 1990-11-20 | 1993-09-07 | Adir Et Compagnie | 3-amino-2-hydroxpyridine |
| FR2669336B1 (fr) * | 1990-11-20 | 1993-01-22 | Adir | Nouveaux derives d'oxazolo pyridines, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent. |
| US5618819A (en) * | 1994-07-07 | 1997-04-08 | Adir Et Compagnie | 1,3-dihydro-2H-pyrrolo[2,3-b]pyridin-2-one and oxazolo[4,5-b]pyridin-2-(3H)-one compounds |
| FR2722196B1 (fr) * | 1994-07-07 | 1996-08-23 | Adir | Nouveaux derives amines de 1,3-dihydro-2h-pyrrolo(2,3-b) pyridin-2-ones et oxazolo(4,5-b) pyridin-2 (3h)-ones, leur procede de preparation et les compositions pharmaceutique qui les contiennent |
| US5723475A (en) * | 1995-02-28 | 1998-03-03 | Suntory Limited | Arylpiperidine and arylpiperazine derivatives and medicament containing the same |
| WO1999065897A1 (en) | 1998-06-19 | 1999-12-23 | Chiron Corporation | Inhibitors of glycogen synthase kinase 3 |
| US7045519B2 (en) * | 1998-06-19 | 2006-05-16 | Chiron Corporation | Inhibitors of glycogen synthase kinase 3 |
| CA2528538A1 (en) * | 2003-06-19 | 2004-12-29 | Psychiatric Genomics, Inc. | Dual function compounds and uses thereof |
| CA2636929A1 (en) * | 2005-12-21 | 2007-07-12 | Decode Genetics, Ehf | Biaryl nitrogen heterocycle inhibitors of lta4h for treating inflammation |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4038396A (en) * | 1975-02-24 | 1977-07-26 | Merck & Co., Inc. | Anti-inflammatory oxazole[4,5-b]pyridines |
| JPS63146872A (ja) * | 1986-07-08 | 1988-06-18 | Yoshitomi Pharmaceut Ind Ltd | ピリミジニルピペラジン化合物 |
| FR2650592B1 (de) * | 1989-08-07 | 1991-11-15 | Science Organisation |
-
1989
- 1989-08-07 FR FR8910597A patent/FR2650591B1/fr not_active Expired - Lifetime
-
1990
- 1990-08-06 NZ NZ234789A patent/NZ234789A/en unknown
- 1990-08-06 AU AU60165/90A patent/AU625886B2/en not_active Ceased
- 1990-08-06 PT PT94929A patent/PT94929A/pt not_active Application Discontinuation
- 1990-08-06 CA CA002022732A patent/CA2022732A1/fr not_active Abandoned
- 1990-08-06 JP JP2207966A patent/JPH0699396B2/ja not_active Expired - Lifetime
- 1990-08-07 ZA ZA906212A patent/ZA906212B/xx unknown
- 1990-08-07 IE IE284590A patent/IE902845A1/en unknown
- 1990-08-07 DE DE69018730T patent/DE69018730D1/de not_active Expired - Lifetime
- 1990-08-07 US US07/564,035 patent/US5084456A/en not_active Expired - Fee Related
- 1990-08-07 OA OA59833A patent/OA09460A/xx unknown
- 1990-08-07 EP EP90402255A patent/EP0412899B1/de not_active Expired - Lifetime
- 1990-08-07 AT AT90402255T patent/ATE121405T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| NZ234789A (en) | 1992-06-25 |
| ZA906212B (en) | 1991-05-29 |
| DE69018730D1 (de) | 1995-05-24 |
| FR2650591B1 (fr) | 1991-11-15 |
| EP0412899A3 (en) | 1991-12-18 |
| JPH0699396B2 (ja) | 1994-12-07 |
| IE902845A1 (en) | 1991-02-27 |
| AU625886B2 (en) | 1992-07-16 |
| JPH0377867A (ja) | 1991-04-03 |
| AU6016590A (en) | 1991-02-07 |
| OA09460A (fr) | 1992-11-15 |
| CA2022732A1 (fr) | 1991-02-08 |
| FR2650591A1 (fr) | 1991-02-08 |
| EP0412899A2 (de) | 1991-02-13 |
| EP0412899B1 (de) | 1995-04-19 |
| US5084456A (en) | 1992-01-28 |
| PT94929A (pt) | 1991-04-18 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE4903T1 (de) | 1-, 6- und 2-substituierte 1-carba-2-penem-3carbons[ure, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zusammensetzungen. | |
| DE69100079D1 (de) | Naphthalin-derivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zusammensetzungen. | |
| DK387889A (da) | Makrolider, og farmaceutiske praeparater med indhold af saadanne forbindelser | |
| DE3380958D1 (de) | Beta-carboline, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate. | |
| DE59005254D1 (de) | 24-Homo-Vitamin-D-Derivate, Verfahren zu ihrer Herstellung; diese Derivate enthaltende pharmazeutische Präparate sowie deren Verwendung als Arzneimittel. | |
| ATE88468T1 (de) | Arylalkoxycumarine, verfahren zu ihrer herstellung und diese enthaltende therapeutische mittel. | |
| ATE121405T1 (de) | Oxazolopyridinderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen. | |
| ATE18549T1 (de) | 1-carboxyalkanoylindolin-2-carbonsaeure-ester, verfahren zu ihrer herstellung, pharmazeutische praeparate enthaltend diese verbindungen, sowie ihre therapeutische verwendung. | |
| OA09349A (fr) | "Nouveaux dérivés du 3-aminochromane, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent". | |
| DE69103630D1 (de) | Oxazolederivate, ihre herstellung und diese enthaltende pharmazeutischen zubereitungen. | |
| ATE116647T1 (de) | Thiophenderivate, verfahren zu deren herstellung und sie enthaltende pharmazeutische zusammensetzungen. | |
| FI853233A0 (fi) | 1,6-naftyridinderivat, foerfarande foer deras framstaellning och dessa innehaollande farmaceutiska produkter. | |
| DE3870167D1 (de) | N-(vinblastinoyl-23)-derivate von 1-aminomethylposphonsaeure, verfahren zu ihrer herstellung und sie enthaltende arzneimittel. | |
| ATE162195T1 (de) | 4-hydroxy-phenyl-beta-d-glukose-monoester, verfahren zur ihrer herstellung und ihre verwendung in der kosmetik, der pharmazie, als zahnpflegemitteln und lebensmitteln | |
| ATE140693T1 (de) | Phenylalkylaminoalkyl-verbindungen sowie verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel | |
| ATE215934T1 (de) | Neue histidinderivate, verfahren zu ihrer herstellung und ihre verwendung als mittel gegen freie radikale | |
| DE3676378D1 (de) | Isoxazolderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutischen praeparate. | |
| AU6306886A (en) | Alkylcarboxamides of pyridylalkylamines, their preparation and their use in human and veterinary medicine | |
| DE69116423D1 (de) | 3'-Deamino-4'-deoxy-4'-amino-8-fluoranthracycline und Verfahren zu ihrer Herstellung | |
| ATE101610T1 (de) | Indol-derivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische praeparate. | |
| ATE130309T1 (de) | 14alpha,16alpha-ethano- und 14alpha,16alpha- ethenoestratriene. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |