ATE121421T1 - Hemmung von migration von zellen mit hilfe von synthetischen peptiden. - Google Patents

Hemmung von migration von zellen mit hilfe von synthetischen peptiden.

Info

Publication number: ATE121421T1
Authority: AT; Austria
Prior art keywords: cells; gly; asp; membrane; arg
Prior art date: 1988-03-10

Application number

AT89103359T

Other languages

English (en)

Inventor

Erkki I Ruoslahti

Michael D Pierschbacher

Kurt R Gehlsen

Original Assignee

Jolla Cancer Res Found

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-03-10

Filing date

1989-02-25

Publication date

1995-05-15

1989-02-25 Application filed by Jolla Cancer Res Found filed Critical Jolla Cancer Res Found

1995-05-15 Application granted granted Critical

1995-05-15 Publication of ATE121421T1 publication Critical patent/ATE121421T1/de

Links

108090000765 processed proteins & peptides Proteins 0.000 title abstract 4
102000004196 processed proteins & peptides Human genes 0.000 title abstract 4
230000005764 inhibitory process Effects 0.000 title 1
230000005012 migration Effects 0.000 title 1
238000013508 migration Methods 0.000 title 1
102000012422 Collagen Type I Human genes 0.000 abstract 2
108010022452 Collagen Type I Proteins 0.000 abstract 2
230000002401 inhibitory effect Effects 0.000 abstract 2
210000004379 membrane Anatomy 0.000 abstract 2
239000012528 membrane Substances 0.000 abstract 2
238000000034 method Methods 0.000 abstract 2
UMZVBZDHGKJFGQ-LLLAAFKUSA-N (2s)-1-[(2s,3r)-2-[[(2s)-2-[[2-[[(2s)-2-[(2-aminoacetyl)amino]-5-(diaminomethylideneamino)pentanoyl]amino]acetyl]amino]-3-carboxypropanoyl]amino]-3-hydroxybutanoyl]pyrrolidine-2-carboxylic acid Chemical compound NC(=N)NCCC[C@H](NC(=O)CN)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H]([C@H](O)C)C(=O)N1CCC[C@H]1C(O)=O UMZVBZDHGKJFGQ-LLLAAFKUSA-N 0.000 abstract 1
IYMAXBFPHPZYIK-BQBZGAKWSA-N Arg-Gly-Asp Chemical compound NC(N)=NCCC[C@H](N)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(O)=O IYMAXBFPHPZYIK-BQBZGAKWSA-N 0.000 abstract 1
102100037362 Fibronectin Human genes 0.000 abstract 1
108010067306 Fibronectins Proteins 0.000 abstract 1
102100035140 Vitronectin Human genes 0.000 abstract 1
108010031318 Vitronectin Proteins 0.000 abstract 1
150000001413 amino acids Chemical group 0.000 abstract 1
210000001691 amnion Anatomy 0.000 abstract 1
108010072041 arginyl-glycyl-aspartic acid Proteins 0.000 abstract 1
238000003556 assay Methods 0.000 abstract 1
108010000421 fibronectin attachment peptide Proteins 0.000 abstract 1
238000000338 in vitro Methods 0.000 abstract 1
230000009545 invasion Effects 0.000 abstract 1
230000003211 malignant effect Effects 0.000 abstract 1
230000000149 penetrating effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
General Chemical & Material Sciences (AREA)
Biochemistry (AREA)
Genetics & Genomics (AREA)
Gastroenterology & Hepatology (AREA)
Molecular Biology (AREA)
Zoology (AREA)
Toxicology (AREA)
Chemical Kinetics & Catalysis (AREA)
Biophysics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

AT89103359T 1988-03-10 1989-02-25 Hemmung von migration von zellen mit hilfe von synthetischen peptiden. ATE121421T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US16653088A	1988-03-10	1988-03-10

Publications (1)

Publication Number	Publication Date
ATE121421T1 true ATE121421T1 (de)	1995-05-15

Family

ID=22603704

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT89103359T ATE121421T1 (de)	1988-03-10	1989-02-25	Hemmung von migration von zellen mit hilfe von synthetischen peptiden.

Country Status (6)

Country	Link
EP (1)	EP0332912B1 (de)
JP (2)	JPH024716A (de)
AT (1)	ATE121421T1 (de)
CA (1)	CA1324954C (de)
DE (1)	DE68922234T2 (de)
ES (1)	ES2073414T3 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP2662830B2 (ja) *	1990-10-26	1997-10-15	富士写真フイルム株式会社	Ｃｍ−キチン誘導体およびその用途
CA2074945A1 (en) *	1990-11-30	1992-05-31	Atsushi Isoai	Tumor cell invasion-inhibiting peptides, peptide complexes and cancer metastasis inhibitors
US5879657A (en) *	1993-03-30	1999-03-09	The Dupont Merck Pharmaceutical Company	Radiolabeled platelet GPIIb/IIIa receptor antagonists as imaging agents for the diagnosis of thromboembolic disorders
WO2003038431A1 (en) *	2001-10-26	2003-05-08	The Regents Of The University Of California	Method for screening combinatorial bead library, capturing cells from body fluids, and ligands for cancer cells
EP1862476B1 (de) *	2003-03-28	2009-12-23	Fuji Film Manufacturing Europe B.V.	RGD-angereicherte, gelatine-ähnliche Proteine zur Verhinderung der Zelladhäsion
WO2009043441A1 (en) *	2007-09-11	2009-04-09	Mondobiotech Laboratories Ag	D-ala-gln-octadecyl ester as a therapeutic agent
KR20100061680A (ko) *	2007-09-11	2010-06-08	몬도바이오테크 래보래토리즈 아게	치료제로서의 ｇｌｙ－ｐｒｏ－ｇｌｕ－ｏｈ（ｇｐｅ）의 용도

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3781263T2 (de) *	1986-12-15	1993-04-08	Inst Nat Sante Rech Med	Peptid-derivate und deren verwendung in der therapie.
IT1222437B (it) *	1987-08-04	1990-09-05	Ellem Ind Farmaceutica	Tripeptidi utili come immunostimolanti e nella prevenzione delle metastasi e relativo procedimento di preparazione

1989
- 1989-02-17 CA CA000591334A patent/CA1324954C/en not_active Expired - Fee Related
- 1989-02-25 DE DE68922234T patent/DE68922234T2/de not_active Expired - Lifetime
- 1989-02-25 ES ES89103359T patent/ES2073414T3/es not_active Expired - Lifetime
- 1989-02-25 AT AT89103359T patent/ATE121421T1/de not_active IP Right Cessation
- 1989-02-25 EP EP89103359A patent/EP0332912B1/de not_active Expired - Lifetime
- 1989-03-09 JP JP1057663A patent/JPH024716A/ja active Pending
1996
- 1996-05-22 JP JP8126684A patent/JP2744902B2/ja not_active Expired - Lifetime

Also Published As

Publication number	Publication date
JP2744902B2 (ja)	1998-04-28
JPH024716A (ja)	1990-01-09
JPH08332097A (ja)	1996-12-17
DE68922234T2 (de)	1995-08-31
DE68922234D1 (de)	1995-05-24
ES2073414T3 (es)	1995-08-16
EP0332912A3 (en)	1989-11-08
EP0332912B1 (de)	1995-04-19
CA1324954C (en)	1993-12-07
EP0332912A2 (de)	1989-09-20

Legal Events

Date	Code	Title	Description
1995-10-15	UEP	Publication of translation of european patent specification
1998-11-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
LU91087I2 (fr)	2004-08-26	Advate(Octocog alfa) soustotes ses formes protégées par le brevet de base.
ATE389666T1 (de)	2008-04-15	Hohe expressionsrate von proteinen
BR9810586A (pt)	2000-09-05	Peptìdio de aglutinação de integrin cìclico, composição farmacêutica que compreende o mesmo, processos para inibição e ensaio de aglutinação para identificar agentes de aglutinação de integrin
PT707594E (pt)	2002-05-31	Separacao de proteinas
DE68922234D1 (de)	1995-05-24	Hemmung von Migration von Zellen mit Hilfe von synthetischen Peptiden.
DE69231567D1 (de)	2000-12-21	Screeningverfahren von morphogenischen Proteinen
SE9803891D0 (sv)	1998-11-13	Protein Variants
ATE271125T1 (de)	2004-07-15	Neuartige tyrosinkinase
Ayad et al.	1986	Type VI collagen and glycoprotein MFPI are distinct components of the extracellular matrix
DE69829953D1 (de)	2005-06-02	Kristallisation von proteinen
DE58901435D1 (de)	1992-06-17	Verfahren zur herstellung von dipeptiden mit n-terminalen nichtproteinogenen aminosaeuren.
DE68904578D1 (de)	1993-03-11	Enzym zur alpha-amidierung von c-termini und verfahren zu dessen herstellung.
WO1995021916A3 (en)	1995-09-08	Pp32: a newly identified cd45-associated protein
Kasinathan et al.	1988	Differences in calcium uptake in native canine cardiac microsomes are correlated with the ratio of unphosphorylated to phosphorylated phospholamban as determined by Western blot analysis
Goldenberg	1985	TYPE I PROCOLLAGEN SYNTHESIS AND TRANSPORT IN CHICK EMBRYO FIBROBLASTS: ROLE OF THE AMINO-TERMINAL PROPEPTIDE AND COATED VESICLES.
ATE76081T1 (de)	1992-05-15	Verfahren zur herstellung von dipeptiden mit nterminalen nichtproteinogenen aminosaeuren.