ATE121618T1 - Gemischte lipid-bicarbonat-kolloidale partikel zur abgabe von arzneien und kalorien. - Google Patents

Gemischte lipid-bicarbonat-kolloidale partikel zur abgabe von arzneien und kalorien.

Info

Publication number: ATE121618T1
Authority: AT; Austria
Prior art keywords: calories; carbon atoms; colloidal particles; particles; bicarbonate
Prior art date: 1990-08-13

Application number

AT91917082T

Other languages

English (en)

Inventor

David W Yesair

Original Assignee

David W Yesair

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-08-13

Filing date

1991-08-12

Publication date

1995-05-15

1991-08-12 Application filed by David W Yesair filed Critical David W Yesair

1995-05-15 Application granted granted Critical

1995-05-15 Publication of ATE121618T1 publication Critical patent/ATE121618T1/de

Links

239000002245 particle Substances 0.000 title abstract 4
PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 abstract 3
125000004432 carbon atom Chemical group C* 0.000 abstract 3
239000000203 mixture Substances 0.000 abstract 3
150000004665 fatty acids Chemical class 0.000 abstract 2
RYCNUMLMNKHWPZ-SNVBAGLBSA-N 1-acetyl-sn-glycero-3-phosphocholine Chemical compound CC(=O)OC[C@@H](O)COP([O-])(=O)OCC[N+](C)(C)C RYCNUMLMNKHWPZ-SNVBAGLBSA-N 0.000 abstract 1
BVKZGUZCCUSVTD-UHFFFAOYSA-M Bicarbonate Chemical compound OC([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-M 0.000 abstract 1
OGBUMNBNEWYMNJ-UHFFFAOYSA-N batilol Chemical class CCCCCCCCCCCCCCCCCCOCC(O)CO OGBUMNBNEWYMNJ-UHFFFAOYSA-N 0.000 abstract 1
239000003833 bile salt Substances 0.000 abstract 1
229940093761 bile salts Drugs 0.000 abstract 1
235000014113 dietary fatty acids Nutrition 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
229940079593 drug Drugs 0.000 abstract 1
239000003925 fat Substances 0.000 abstract 1
229930195729 fatty acid Natural products 0.000 abstract 1
239000000194 fatty acid Substances 0.000 abstract 1
235000021588 free fatty acids Nutrition 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1
150000005830 nonesterified fatty acids Chemical class 0.000 abstract 1
230000000699 topical effect Effects 0.000 abstract 1
239000003981 vehicle Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Epidemiology (AREA)
Molecular Biology (AREA)
Dispersion Chemistry (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Biophysics (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

AT91917082T 1990-08-13 1991-08-12 Gemischte lipid-bicarbonat-kolloidale partikel zur abgabe von arzneien und kalorien. ATE121618T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US56724390A	1990-08-13	1990-08-13

Publications (1)

Publication Number	Publication Date
ATE121618T1 true ATE121618T1 (de)	1995-05-15

Family

ID=24266341

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT91917082T ATE121618T1 (de)	1990-08-13	1991-08-12	Gemischte lipid-bicarbonat-kolloidale partikel zur abgabe von arzneien und kalorien.

Country Status (9)

Country	Link
US (3)	US5314921A (de)
EP (1)	EP0543943B1 (de)
JP (1)	JP3273785B2 (de)
AT (1)	ATE121618T1 (de)
AU (1)	AU666293B2 (de)
CA (1)	CA2089003C (de)
DE (1)	DE69109297T2 (de)
ES (1)	ES2071332T3 (de)
WO (1)	WO1992003121A1 (de)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5891466A (en) *	1990-08-13	1999-04-06	Yesair; David W.	Mixed Liped-Bicarbonate colloidal particles for delivering drugs or calories
CA2089003C (en) *	1990-08-13	2001-03-20	David W. Yesair	Mixed lipid-bicarbonate colloidal particles for delivering drugs or calories
GB9212511D0 (en) *	1992-06-12	1992-07-22	Cortecs Ltd	Pharmaceutical compositions
US5514670A (en) *	1993-08-13	1996-05-07	Pharmos Corporation	Submicron emulsions for delivery of peptides
US5744155A (en) *	1993-08-13	1998-04-28	Friedman; Doron	Bioadhesive emulsion preparations for enhanced drug delivery
ATE161527T1 (de) *	1994-03-14	1998-01-15	Morten Sloth Weidner	Methode zur solubilisierung organischer verbindungen in lipophilen systemen ,neue chemische komplexe solcher verbindungen und verschiedene anwendungen dieser komplexe
DE69614855T2 (de) *	1995-06-06	2002-03-28	Biomolecular Products, Inc.	Gemischte lipid-bicarbonat kolloidale partikel zur abgabe von arzneistoffen oder kalorien
ATE277596T1 (de) *	1997-02-24	2004-10-15	Sla Pharma Ag	Topische pharmazeutische zusammensetzung, enthaltend einen cholinergischen wirkstoff oder einen kalziumkanalblocker
US6086915A (en) *	1998-04-01	2000-07-11	Bioresponse L.L.C.	Compositions and methods of adjusting steroid hormone metabolism through phytochemicals
US6524620B2 (en)	1998-07-20	2003-02-25	Andrx Pharmaceuticals, Inc.	Diltiazem controlled release formulation and method of manufacture
IL141801A0 (en)	1998-09-08	2002-03-10	Biomolecular Products Inc	Methods and compositions for increasing intestinal absorption of fats
US6172122B1 (en)	1998-12-17	2001-01-09	The Lubrizol Corporation	Stable emulsions from gelled overbased substrates with surfactants and aqueous liquids
US6294192B1 (en)	1999-02-26	2001-09-25	Lipocine, Inc.	Triglyceride-free compositions and methods for improved delivery of hydrophobic therapeutic agents
US6761903B2 (en)	1999-06-30	2004-07-13	Lipocine, Inc.	Clear oil-containing pharmaceutical compositions containing a therapeutic agent
US6267985B1 (en)	1999-06-30	2001-07-31	Lipocine Inc.	Clear oil-containing pharmaceutical compositions
US6248363B1 (en) *	1999-11-23	2001-06-19	Lipocine, Inc.	Solid carriers for improved delivery of active ingredients in pharmaceutical compositions
US6383471B1 (en)	1999-04-06	2002-05-07	Lipocine, Inc.	Compositions and methods for improved delivery of ionizable hydrophobic therapeutic agents
US6458383B2 (en)	1999-08-17	2002-10-01	Lipocine, Inc.	Pharmaceutical dosage form for oral administration of hydrophilic drugs, particularly low molecular weight heparin
US20030236236A1 (en) *	1999-06-30	2003-12-25	Feng-Jing Chen	Pharmaceutical compositions and dosage forms for administration of hydrophobic drugs
US6309663B1 (en)	1999-08-17	2001-10-30	Lipocine Inc.	Triglyceride-free compositions and methods for enhanced absorption of hydrophilic therapeutic agents
US7732404B2 (en) *	1999-12-30	2010-06-08	Dexcel Ltd	Pro-nanodispersion for the delivery of cyclosporin
US6861060B1 (en)	2000-04-21	2005-03-01	Elena Luriya	Personal care formulations
JP4384409B2 (ja) *	2000-12-05	2009-12-16	チルドレンズ・ホスピタル・ロス・アンジエルス	バイオアベイラビリティが増加したフェンレチニドの医薬組成物、およびその使用方法
EP1434593B1 (de)	2001-10-11	2017-03-29	Biomolecular Products, Inc.	MODIFIKATIONEN FESTER 3-sn-PHOSPHOGLYCERIDE
US20050008686A1 (en) *	2003-01-15	2005-01-13	Mannino Raphael J.	Cochleate preparations of fragile nutrients
CA2513260C (en) *	2003-01-31	2013-01-08	Childrens Hospital Los Angeles	Oral compositions of fenretinide having increased bioavailability and methods of using the same
DE60317063T2 (de) *	2003-09-18	2008-08-07	Técnimede-Sociedade Técnico-Medicinal, S.A.	Stabile Diltiazemhydrochlorid enthaltende pharmazeutische Zusammensetzung zur Anwendung auf der Haut und Verfahren zu ihrer Herstellung
US20060003002A1 (en) *	2003-11-03	2006-01-05	Lipocine, Inc.	Pharmaceutical compositions with synchronized solubilizer release
AU2007233155B2 (en)	2006-03-29	2012-04-26	Scitech Development Llc	Liposomal nanoparticles and other formulations of fenretinide for use in therapy and drug delivery
EP2200613B1 (de)	2007-09-21	2018-09-05	The Johns Hopkins University	Phenazin-derivate und ihre verwendungen
CA2718416C (en) *	2008-03-13	2018-01-02	Mallinckrodt Inc.	Multi-function, foot-activated controller for imaging system
US11304960B2 (en)	2009-01-08	2022-04-19	Chandrashekar Giliyar	Steroidal compositions
US9034858B2 (en)	2010-11-30	2015-05-19	Lipocine Inc.	High-strength testosterone undecanoate compositions
US9358241B2 (en)	2010-11-30	2016-06-07	Lipocine Inc.	High-strength testosterone undecanoate compositions
US20180153904A1 (en)	2010-11-30	2018-06-07	Lipocine Inc.	High-strength testosterone undecanoate compositions
US20120148675A1 (en)	2010-12-10	2012-06-14	Basawaraj Chickmath	Testosterone undecanoate compositions
US9498485B2 (en)	2014-08-28	2016-11-22	Lipocine Inc.	Bioavailable solid state (17-β)-hydroxy-4-androsten-3-one esters
WO2016033549A2 (en)	2014-08-28	2016-03-03	Lipocine Inc.	(17-ß)-3-OXOANDROST-4-EN-17-YL TRIDECANOATE COMPOSITIONS AND METHODS OF THEIR PREPARATION AND USE
US20160361322A1 (en)	2015-06-15	2016-12-15	Lipocine Inc.	Composition and method for oral delivery of androgen prodrugs
US11559530B2 (en)	2016-11-28	2023-01-24	Lipocine Inc.	Oral testosterone undecanoate therapy
WO2020018974A1 (en)	2018-07-20	2020-01-23	Lipocine Inc.	Liver disease

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA725596A (en) *	1960-08-26	1966-01-11	J. Wretlind Arvid	Method of preparing intravenously injectable fat emulsions free from side reactions or complications
JPS5321393B2 (de) *	1974-10-19	1978-07-03
JPS53107408A (en) *	1977-02-28	1978-09-19	Yamanouchi Pharmaceut Co Ltd	Micellar preparation for rectal infusion
FR2427100A1 (fr) *	1978-06-02	1979-12-28	Kali Chemie Pharma Gmbh	Composition pharmaceutique a propriete de resorption amelioree et procede pour sa fabrication
JPS6030652B2 (ja) *	1979-05-07	1985-07-17	株式会社ミドリ十字	静脈注射用脂肪乳剤
JPS5618914A (en) *	1979-07-25	1981-02-23	Eisai Co Ltd	Ubidecarenone composition having good absorbability
FR2497668B1 (fr) *	1981-01-15	1986-03-21	Gattefosse Ets Sa	Emulsions lipoproteiques injectables, leur procede de preparation et leurs applications en therapeutique
JPS57167926A (en) *	1981-04-08	1982-10-16	Mitsubishi Chem Ind Ltd	External base for skin
EP0084052A1 (de) *	1981-07-23	1983-07-27	Arthur D. Little, Inc.	Verabreichungssystem für mizellulare arzneimittel
US4454113A (en) *	1982-09-21	1984-06-12	Scm Corporation	Stabilization of oil and water emulsions using polyglycerol esters of fatty acids
US4874795A (en) *	1985-04-02	1989-10-17	Yesair David W	Composition for delivery of orally administered drugs and other substances
IE59067B1 (en) *	1985-04-02	1993-12-15	Yesair David W	Composition for delivery of orally administered drugs and other substances
US4849132A (en) *	1986-05-16	1989-07-18	Asahi Denka Kogyo Kabushiki Kaisha	Surfactant composition having improved functions
CA2089003C (en) *	1990-08-13	2001-03-20	David W. Yesair	Mixed lipid-bicarbonate colloidal particles for delivering drugs or calories

1991
- 1991-08-12 CA CA002089003A patent/CA2089003C/en not_active Expired - Lifetime
- 1991-08-12 AU AU86462/91A patent/AU666293B2/en not_active Ceased
- 1991-08-12 JP JP51750491A patent/JP3273785B2/ja not_active Expired - Lifetime
- 1991-08-12 ES ES91917082T patent/ES2071332T3/es not_active Expired - Lifetime
- 1991-08-12 WO PCT/US1991/005716 patent/WO1992003121A1/en not_active Ceased
- 1991-08-12 EP EP19910917082 patent/EP0543943B1/de not_active Expired - Lifetime
- 1991-08-12 DE DE69109297T patent/DE69109297T2/de not_active Expired - Fee Related
- 1991-08-12 AT AT91917082T patent/ATE121618T1/de not_active IP Right Cessation
1992
- 1992-06-30 US US07/908,442 patent/US5314921A/en not_active Expired - Lifetime
1994
- 1994-05-05 US US08/238,592 patent/US5741822A/en not_active Expired - Lifetime
1995
- 1995-05-24 US US08/449,225 patent/US5707873A/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
US5314921A (en)	1994-05-24
WO1992003121A1 (en)	1992-03-05
US5707873A (en)	1998-01-13
JP3273785B2 (ja)	2002-04-15
EP0543943B1 (de)	1995-04-26
DE69109297D1 (de)	1995-06-01
US5741822A (en)	1998-04-21
CA2089003A1 (en)	1992-02-14
EP0543943A1 (de)	1993-06-02
CA2089003C (en)	2001-03-20
ES2071332T3 (es)	1995-06-16
AU8646291A (en)	1992-03-17
AU666293B2 (en)	1996-02-08
DE69109297T2 (de)	1995-11-09
JPH06503815A (ja)	1994-04-28

Legal Events

Date	Code	Title	Description
1995-11-15	UEP	Publication of translation of european patent specification
2003-05-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
ATE121618T1 (de)	1995-05-15	Gemischte lipid-bicarbonat-kolloidale partikel zur abgabe von arzneien und kalorien.
ZA200005915B (en)	2001-10-23	Pharmaceutical compositions capable of being gelled.
ATE183926T1 (de)	1999-09-15	Hautpermeabilitaetserhöher bestehend aus monoglycerid/laktat estern
MY110734A (en)	1996-11-30	Improvements in or relating to dioic acids.
DE3172223D1 (en)	1985-10-17	Edible, pharmaceutical compositions and processes for making thereof
AU2671292A (en)	1993-05-03	Use of an emulsion to prepare an intravenously administered medicament for treating skin diseases
SI9520139B (sl)	1999-02-28	Halkoni in njihovi estri z antiproliferativno učinkovitostjo na tumorje maternice, jajčnikov in dojk
EP0137543A3 (en)	1987-09-02	Pharmaceutical composition for the therapy of peripheral arteriopathies
AU1145483A (en)	1983-09-08	Linoleic acid and essential fatty acid compositions as
AU1145683A (en)	1983-09-08	Composition containing an essential fatty acid and niacin and/or a bile salt binder
PT84657B (pt)	1989-11-30	Processo para a fluidificacao, mediante glicofurol, de composicoes farmaceuticas contendo fosfatidil-colina, destinadas a serem introduzidas em capsulas moles de gelatina
DE69614855D1 (de)	2001-10-04	Gemischte lipid-bicarbonat kolloidale partikel zur abgabe von arzneistoffen oder kalorien
JPH09309813A (ja)	1997-12-02	皮膚外用剤
HUT52388A (en)	1990-07-28	Process for producing pharmaceutical compositions comprising unsaturated fatty acids and selenium as active ingredient
KR890701098A (ko)	1989-12-19	히드로퀴논 및 코지산을 함유하는 제약 또는 화장제 조성물
NZ332497A (en)	1999-05-28	Pharmaceutical composition having a carrier system containing a combination of an alkylene glycol and unsaturated fatty acid alcohol as the solvent and a stiffening agent
EP0238198A3 (de)	1990-05-30	Verfahren zur Abänderung der Lipid-Struktur-Funktion und von Zellmembranen und pharmazeutische Zusammensetzungen zur Verwendung dabei
MY111719A (en)	2000-11-30	Psoriasis treatment
SE8104657L (sv)	1982-02-05	Injicerbara farmaceutiska kompositioner
ES2172172T3 (es)	2002-09-16	Composiciones farmaceuticas solidas para la administracion por via oral que permiten la liberacion modulada de nicorandil y su procedimiento de preparacion.
GB8804188D0 (en)	1988-03-23	Pharmaceutical compositions
ZA873771B (en)	1987-11-20	A composition for transdermal therapeutic systems of loop diuretics and a process for its preparation
YU48388B (sh)	1998-07-10	Postupak za dobijanje farmaceutske masti koja ne iritira kožu
IT1226144B (it)	1990-12-19	Di estere fosforico dell'acido ursodeossicolico e suoi derivati, processo per la loro preparazione e composizioni terapeutiche che li contengono come principi attivi.
DK576086A (da)	1987-01-30	Blanding til afgivelse af oralt indgivelige stoffer