ATE121944T1 - Verwendungen von rekombinantem koloniestimulierendem faktor-1. - Google Patents

Verwendungen von rekombinantem koloniestimulierendem faktor-1.

Info

Publication number
ATE121944T1
ATE121944T1 AT88908821T AT88908821T ATE121944T1 AT E121944 T1 ATE121944 T1 AT E121944T1 AT 88908821 T AT88908821 T AT 88908821T AT 88908821 T AT88908821 T AT 88908821T AT E121944 T1 ATE121944 T1 AT E121944T1
Authority
AT
Austria
Prior art keywords
stimulating factor
recombinant colony
colony
recombinant
leukopenia
Prior art date
Application number
AT88908821T
Other languages
English (en)
Inventor
Peter Ralph
Mary Kim Warren
Kong Teck Chong
James J Devlin
Robert Zimmerman
Original Assignee
Cetus Oncology Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/099,872 external-priority patent/US5104650A/en
Application filed by Cetus Oncology Corp filed Critical Cetus Oncology Corp
Application granted granted Critical
Publication of ATE121944T1 publication Critical patent/ATE121944T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/191—Tumor necrosis factors [TNF], e.g. lymphotoxin [LT], i.e. TNF-beta
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A61K38/2013—IL-2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/53—Colony-stimulating factor [CSF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Biophysics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT88908821T 1987-09-22 1988-09-16 Verwendungen von rekombinantem koloniestimulierendem faktor-1. ATE121944T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/099,872 US5104650A (en) 1985-02-05 1987-09-22 Uses of recombinant colony stimulating factor-1
US24325388A 1988-09-14 1988-09-14

Publications (1)

Publication Number Publication Date
ATE121944T1 true ATE121944T1 (de) 1995-05-15

Family

ID=26796577

Family Applications (2)

Application Number Title Priority Date Filing Date
AT94202534T ATE213950T1 (de) 1987-09-22 1988-09-16 Verwendung von rekombinantem koloniestimulierendem faktor-1 zur herstellung eines medikaments gegen cytomegalovirusinfektionen
AT88908821T ATE121944T1 (de) 1987-09-22 1988-09-16 Verwendungen von rekombinantem koloniestimulierendem faktor-1.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT94202534T ATE213950T1 (de) 1987-09-22 1988-09-16 Verwendung von rekombinantem koloniestimulierendem faktor-1 zur herstellung eines medikaments gegen cytomegalovirusinfektionen

Country Status (7)

Country Link
EP (3) EP0643972B1 (de)
JP (2) JP2831012B2 (de)
AT (2) ATE213950T1 (de)
AU (1) AU625807B2 (de)
CA (1) CA1322158C (de)
DE (2) DE3853721T2 (de)
WO (1) WO1989002746A1 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5556620A (en) * 1985-02-05 1996-09-17 Cetus Oncology Corporation Use of recombinant colony stimulating factor-1 to enhance wound healing
US5837229A (en) * 1985-02-05 1998-11-17 Chiron Corporation Uses of recombinant colony stimulating factor-1
US5104650A (en) * 1985-02-05 1992-04-14 Cetus Corporation Uses of recombinant colony stimulating factor-1
US5422105A (en) * 1985-02-05 1995-06-06 Cetus Oncology Corporation Use of recombinant colony stimulating factor 1
DE3853721T2 (de) * 1987-09-22 1995-10-19 Cetus Oncology Corp Verwendungen von rekombinantem koloniestimulierendem faktor-1.
AU5355790A (en) * 1989-04-19 1990-11-16 Cetus Corporation Multifunctional m-csf proteins and genes encoding therefor
WO1991008754A1 (fr) * 1989-12-13 1991-06-27 Otsuka Pharmaceutical Co., Ltd. Application medicinale de m-csf
US5714140A (en) * 1989-12-13 1998-02-03 Otsuka Pharmaceutical Co., Ltd. Method for inhibiting the production of bioactive IL-1 by administering M-CSF
JP3501801B2 (ja) * 1990-08-23 2004-03-02 カイロン コーポレイション 組み換えコロニー刺激因子―１の使用
US5087453A (en) * 1990-11-01 1992-02-11 Otsuka Pharmaceutical Co., Ltd. Method for the treatment of bacterial caused weight loss and/or hypoglycemia
JP2001517079A (ja) * 1997-03-04 2001-10-02 カイロン コーポレイション Ｍ−ＣＳＦαの組成物および方法
AU2003202988A1 (en) 2002-01-14 2003-07-30 The Board Of Trustees Of The University Of Illinois Use of modified pyrimidine compounds to promote stem cell migration and proliferation
RU2256471C1 (ru) * 2003-11-13 2005-07-20 Мориков Дмитрий Дмитриевич Способ лечения лейкопении при химиолучевой терапии
US8047999B2 (en) 2008-09-19 2011-11-01 Medtronic, Inc. Filtering of a physiologic signal in a medical device
US9913880B2 (en) * 2011-02-18 2018-03-13 Stemdr Inc. Method of treating sepsis or septic shock
CN110662762A (zh) 2017-05-24 2020-01-07 诺华股份有限公司 抗体细胞因子移植蛋白和用于治疗癌症的方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4230697A (en) * 1978-07-03 1980-10-28 Morinaga Milk Industry Co. Ltd. Virus-inactivated HGI-glycoprotein capable of stimulating proliferation and differentiation of human granulocyte, process for preparing same and leukopenia curative containing same
US4342828A (en) * 1979-07-20 1982-08-03 Morinaga Milk Industry Co., Ltd. Method for producing substance capable of stimulating differentiation and proliferation of human granulopoietic stem cells
AU594045B2 (en) * 1985-02-05 1990-03-01 Chiron Corporation Recombinant colony stimulating factor-1
DE3686794T2 (de) * 1985-02-05 1993-03-04 Cetus Oncology Corp Reinigung des natuerlichen kolonie-stimulierenden faktors-1.
US4847201A (en) * 1985-02-05 1989-07-11 Cetus Corporation DNA encoding for CSF-1 and accompanying recombinant systems
DE3686582T2 (de) * 1985-11-27 1993-01-28 Genetics Inst Behandlung einer krankheit vom aids-typ.
JPS62169799A (ja) * 1986-01-22 1987-07-25 Otsuka Pharmaceut Co Ltd マクロフア−ジ分化増殖促進物質
HU212277B (en) * 1986-05-06 1996-04-29 Genetics Inst Process for producing m-csf
JP2583770B2 (ja) * 1986-09-17 1997-02-19 大塚製薬株式会社 遺伝子
AU8313187A (en) * 1986-12-31 1988-07-07 Cetus Corporation Pharmaceutical composition of colony stimulating factor-i and granulocyte colony stimulating factor
WO1988006452A1 (en) * 1987-03-02 1988-09-07 Genetics Institute, Inc. Compositions for enhancing adcc therapy
DE3853721T2 (de) * 1987-09-22 1995-10-19 Cetus Oncology Corp Verwendungen von rekombinantem koloniestimulierendem faktor-1.
DK54589A (da) * 1988-02-08 1989-08-09 Otsuka Pharma Co Ltd Humane kolonistmulerende faktorer

Also Published As

Publication number Publication date
DE3853721T2 (de) 1995-10-19
JPH09328435A (ja) 1997-12-22
JPH03501382A (ja) 1991-03-28
DE3856516T2 (de) 2002-10-10
EP0379522B1 (de) 1995-05-03
EP1175911A3 (de) 2003-01-15
DE3856516D1 (de) 2002-04-11
WO1989002746A1 (en) 1989-04-06
DE3853721D1 (de) 1995-06-08
JP2846629B2 (ja) 1999-01-13
EP0643972A3 (de) 1995-05-17
EP0379522A1 (de) 1990-08-01
AU625807B2 (en) 1992-07-16
EP0643972B1 (de) 2002-03-06
JP2831012B2 (ja) 1998-12-02
EP0643972A2 (de) 1995-03-22
CA1322158C (en) 1993-09-14
ATE213950T1 (de) 2002-03-15
AU2527888A (en) 1989-04-18
EP1175911A2 (de) 2002-01-30

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EELA Cancelled due to lapse of time