ATE122564T1 - Kombinierung von tobramycin und steroiden für topische ophthalmische verwendung. - Google Patents

Kombinierung von tobramycin und steroiden für topische ophthalmische verwendung.

Info

Publication number: ATE122564T1
Authority: AT; Austria
Prior art keywords: tobramycin; topical ophthalmic; steroids; combination; ophthalmic use
Prior art date: 1988-03-09

Application number

AT89903311T

Other languages

English (en)

Inventor

Gerald D Cagle

Thomas O Mcdonald

Allan L Rosenthal

Original Assignee

Alcon Lab Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-03-09

Filing date

1989-03-09

Publication date

1995-06-15

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27168261&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE122564(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1989-03-09 Application filed by Alcon Lab Inc filed Critical Alcon Lab Inc

1995-06-15 Application granted granted Critical

1995-06-15 Publication of ATE122564T1 publication Critical patent/ATE122564T1/de

Links

150000003431 steroids Chemical class 0.000 title abstract 2
NLVFBUXFDBBNBW-PBSUHMDJSA-N tobramycin Chemical compound N[C@@H]1C[C@H](O)[C@@H](CN)O[C@@H]1O[C@H]1[C@H](O)[C@@H](O[C@@H]2[C@@H]([C@@H](N)[C@H](O)[C@@H](CO)O2)O)[C@H](N)C[C@@H]1N NLVFBUXFDBBNBW-PBSUHMDJSA-N 0.000 title abstract 2
229960000707 tobramycin Drugs 0.000 title abstract 2
230000000699 topical effect Effects 0.000 title abstract 2
229960003957 dexamethasone Drugs 0.000 abstract 1
UREBDLICKHMUKA-CXSFZGCWSA-N dexamethasone Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(F)[C@@H]1[C@@H]1C[C@@H](C)[C@@](C(=O)CO)(O)[C@@]1(C)C[C@@H]2O UREBDLICKHMUKA-CXSFZGCWSA-N 0.000 abstract 1
229960001048 fluorometholone Drugs 0.000 abstract 1
FAOZLTXFLGPHNG-KNAQIMQKSA-N fluorometholone Chemical compound C([C@@]12C)=CC(=O)C=C1[C@@H](C)C[C@@H]1[C@]2(F)[C@@H](O)C[C@]2(C)[C@@](O)(C(C)=O)CC[C@H]21 FAOZLTXFLGPHNG-KNAQIMQKSA-N 0.000 abstract 1
208000015181 infectious disease Diseases 0.000 abstract 1
230000028709 inflammatory response Effects 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
238000010606 normalization Methods 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
230000029663 wound healing Effects 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Ophthalmology & Optometry (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Molecular Biology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Steroid Compounds (AREA)

AT89903311T 1988-03-09 1989-03-09 Kombinierung von tobramycin und steroiden für topische ophthalmische verwendung. ATE122564T1 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US16595288A	1988-03-09	1988-03-09
US16595088A	1988-03-09	1988-03-09
CA000595747A CA1338554C (en)	1988-03-09	1989-04-05	Combination of tobramycin and steroids for topical ophthalmic use

Publications (1)

Publication Number	Publication Date
ATE122564T1 true ATE122564T1 (de)	1995-06-15

Family

ID=27168261

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT89903311T ATE122564T1 (de)	1988-03-09	1989-03-09	Kombinierung von tobramycin und steroiden für topische ophthalmische verwendung.

Country Status (7)

Country	Link
EP (1)	EP0365613B1 (de)
JP (2)	JP2617139B2 (de)
AT (1)	ATE122564T1 (de)
AU (1)	AU606515B2 (de)
CA (1)	CA1338554C (de)
DE (1)	DE68922688T2 (de)
WO (1)	WO1989009057A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU606515B2 (en)	1988-03-09	1991-02-07	Alcon Laboratories, Inc.	Combination of tobramycin and steroids for topical ophthalmic use
ES2078175B1 (es) *	1993-12-31	1996-10-16	Cusi Lab	Formulacion farmaceutica conteniendo clobetasona y tobramicina y sus aplicaciones.
ES2079320B1 (es) *	1994-05-17	1996-10-16	Cusi Lab	Disolucion oftalmica a base de un diclofenaco y tobramicina y sus aplicaciones.
ZA966579B (en) *	1995-08-04	1998-02-02	Wakamoto Pharma Co Ltd	O/W emulsion composition for eye drops.
US7767217B2 (en)	2006-03-14	2010-08-03	Foresight Biotherapeutics	Ophthalmic compositions comprising povidone-iodine
CN102118973A (zh) *	2008-06-12	2011-07-06	前瞻生物治疗公司	一种眼科组合物中新的防腐剂替代物聚维酮碘
WO2012073856A1 (ja) *	2010-11-29	2012-06-07	千寿製薬株式会社	ジフルプレドナートおよびトブラマイシンを含有する水中油型エマルジョン組成物
US9986993B2 (en)	2014-02-11	2018-06-05	Tendyne Holdings, Inc.	Adjustable tether and epicardial pad system for prosthetic heart valve
IT201900003529A1 (it) *	2019-03-11	2020-09-11	Ntc S R L	Riduzione della posologia antibiotica in composizioni antibiotico/antinfiammatorio in associazione tra loro per uso oftalmico

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4271143A (en)	1978-01-25	1981-06-02	Alcon Laboratories, Inc.	Sustained release ophthalmic drug dosage
US4407792A (en) *	1979-05-09	1983-10-04	Alcon Laboratories, Inc.	Sustained release ophthalmic drug dosage
US4478822A (en) *	1983-05-16	1984-10-23	Merck & Co., Inc.	Drug delivery system utilizing thermosetting gels
US4474753A (en) *	1983-05-16	1984-10-02	Merck & Co., Inc.	Topical drug delivery system utilizing thermosetting gels
US4668506A (en) *	1985-08-16	1987-05-26	Bausch & Lomb Incorporated	Sustained-release formulation containing and amino acid polymer
AU606515B2 (en)	1988-03-09	1991-02-07	Alcon Laboratories, Inc.	Combination of tobramycin and steroids for topical ophthalmic use

1989
- 1989-03-09 AU AU33476/89A patent/AU606515B2/en not_active Expired
- 1989-03-09 WO PCT/US1989/000952 patent/WO1989009057A1/en not_active Ceased
- 1989-03-09 EP EP89903311A patent/EP0365613B1/de not_active Expired - Lifetime
- 1989-03-09 JP JP1503167A patent/JP2617139B2/ja not_active Expired - Lifetime
- 1989-03-09 DE DE68922688T patent/DE68922688T2/de not_active Expired - Lifetime
- 1989-03-09 AT AT89903311T patent/ATE122564T1/de not_active IP Right Cessation
- 1989-04-05 CA CA000595747A patent/CA1338554C/en not_active Expired - Lifetime
1995
- 1995-12-12 JP JP34613695A patent/JP2997202B2/ja not_active Expired - Lifetime

Also Published As

Publication number	Publication date
WO1989009057A1 (en)	1989-10-05
JPH02503439A (ja)	1990-10-18
JP2617139B2 (ja)	1997-06-04
DE68922688D1 (de)	1995-06-22
AU3347689A (en)	1989-10-16
DE68922688T2 (de)	1995-10-26
AU606515B2 (en)	1991-02-07
CA1338554C (en)	1996-08-27
EP0365613A4 (en)	1990-09-05
EP0365613B1 (de)	1995-05-17
JP2997202B2 (ja)	2000-01-11
JPH08231405A (ja)	1996-09-10
EP0365613A1 (de)	1990-05-02

Similar Documents

Publication	Publication Date	Title
DE69231486D1 (de)	2000-11-02	Zusammensetzung enthaltend pdgf und dexamethason zur förderung von gewebsreparatur und -regenerierung
DE68915958D1 (de)	1994-07-14	Verwendung angiostatischer Steroide zur Herstellung von Artzneimitteln zur Kontrolle von Augenhochdruck.
DE69527996D1 (de)	2002-10-02	Handprogrammiereinrichtung für patienten für einen implantierbaren stimulator für menschliches gewebe
FI970489A7 (fi)	1997-02-05	Paikallisesti käytettäviä silmälääkekoostumuksia, jotka sisältävät dok sepiinijohdoksia ja soveltuvat allergisten silmäsairauksien hoitoon
UA42747C2 (uk)	2001-11-15	Похідні пептиду,фармацевтична композиція та спосіб стимулювання секреції гормону росту
EP0489108A4 (en)	1992-10-28	Method and composition for the treatment of cutaneous, ocular, and mucosal hypersensitivity, inflammation, and hyperproliferative conditions using topical preparations of serotonin antagonists
CA2069483A1 (en)	1991-08-22	Steroid sulphatase inhibitors
DE69007964T2 (de)	1994-09-22	Verwendung von Thrombospondin zur Beschleunigung der Wundheilung.
ATE170077T1 (de)	1998-09-15	Verfahren zur behandlung von krebs durch kombinationstherapie mit 2'- halomethylidenderivaten und einem s- oder m-phase spezifischen antineoplastischen wirkstoff
DE68922688D1 (de)	1995-06-22	Kombinierung von tobramycin und steroiden für topische ophthalmische verwendung.
ES2052733T3 (es)	1994-07-16	Dispositivo electroterapeutico de baja frecuencia.
NO20004282D0 (no)	2000-08-25	Matriksproteinpreparater for sÕrheling
DE3788004D1 (de)	1993-12-09	Verwendung von Tetrahydrocortisol in der Therapie von Glaukom.
EP0832100A4 (de)	1998-09-02	Neuartige metalloprotease-inhibitoren, diese enthaltende pharmazeutische zusammensetzungen und anwendungsverfahren
ATE131060T1 (de)	1995-12-15	Chenodeoxycholsäure oder ursodeoxycholsäure zur behandlung von erkrankungen der atmungsorgane.
DE69716460D1 (de)	2002-11-21	Wundheilung und behandlung von fibrose
ATE184795T1 (de)	1999-10-15	Verwendung von steroiden mit antioxidativen eigenschaften zur herstellung von pharmazeutischen präparaten zur medikamentösen substitution beim mann
AU3401093A (en)	1993-09-09	Therapeutic agent for threatened abortion
DK0821969T3 (da)	2007-03-26	Medicinsk sammensætning omfattende TCF-II
EP0456842A4 (en)	1992-07-22	Medicinal application of m-csf
Shelley et al.	1969	Surgical eradication of familial benign chronic pemphigus from the axillae: Report of a case
SU1228821A1 (ru)	1986-05-07	Способ лечени инфицированных ран
DE4331945A1 (de)	1995-03-23	Mittel zur externen lokalen Behandlung von Juckreiz
DD222497A1 (de)	1985-05-22	Steifer wundverband, insbesondere wundhaube
PT1007085E (pt)	2002-05-31	Utilizacao da hormona de crescimento em composicoes para o tratamento da resistencia a insulina no coracao

Legal Events

Date	Code	Title	Description
1995-12-15	UEP	Publication of translation of european patent specification
2009-06-15	EELA	Cancelled due to lapse of time