ATE123524T1 - Herstellungsverfahren für chymosin. - Google Patents
Herstellungsverfahren für chymosin.Info
- Publication number
- ATE123524T1 ATE123524T1 AT92907324T AT92907324T ATE123524T1 AT E123524 T1 ATE123524 T1 AT E123524T1 AT 92907324 T AT92907324 T AT 92907324T AT 92907324 T AT92907324 T AT 92907324T AT E123524 T1 ATE123524 T1 AT E123524T1
- Authority
- AT
- Austria
- Prior art keywords
- chymosin
- prochymosin
- filamentous fungus
- derivative
- sequence encoding
- Prior art date
Links
- 108090000746 Chymosin Proteins 0.000 title abstract 3
- 229940080701 chymosin Drugs 0.000 title abstract 3
- GNOLWGAJQVLBSM-UHFFFAOYSA-N n,n,5,7-tetramethyl-1,2,3,4-tetrahydronaphthalen-1-amine Chemical compound C1=C(C)C=C2C(N(C)C)CCCC2=C1C GNOLWGAJQVLBSM-UHFFFAOYSA-N 0.000 title abstract 3
- 238000004519 manufacturing process Methods 0.000 title 1
- 241000233866 Fungi Species 0.000 abstract 3
- 108010064037 prorennin Proteins 0.000 abstract 3
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 2
- 108010076504 Protein Sorting Signals Proteins 0.000 abstract 2
- 108010065511 Amylases Proteins 0.000 abstract 1
- 240000006439 Aspergillus oryzae Species 0.000 abstract 1
- 235000002247 Aspergillus oryzae Nutrition 0.000 abstract 1
- 238000012258 culturing Methods 0.000 abstract 1
- 239000001963 growth medium Substances 0.000 abstract 1
- 239000002609 medium Substances 0.000 abstract 1
- 230000001131 transforming effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6478—Aspartic endopeptidases (3.4.23)
- C12N9/6483—Chymosin (3.4.23.4), i.e. rennin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/23—Aspartic endopeptidases (3.4.23)
- C12Y304/23004—Chymosin (3.4.23.4), i.e. rennin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Mycology (AREA)
- Medicinal Chemistry (AREA)
- Enzymes And Modification Thereof (AREA)
- Saccharide Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP91610020 | 1991-03-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE123524T1 true ATE123524T1 (de) | 1995-06-15 |
Family
ID=8208768
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT92907324T ATE123524T1 (de) | 1991-03-22 | 1992-03-20 | Herstellungsverfahren für chymosin. |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP0575462B1 (de) |
| JP (1) | JPH06505873A (de) |
| AT (1) | ATE123524T1 (de) |
| AU (1) | AU1430992A (de) |
| DE (1) | DE69202858T2 (de) |
| DK (1) | DK0575462T3 (de) |
| WO (1) | WO1992016633A1 (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5480801A (en) * | 1993-09-17 | 1996-01-02 | Novo Nordisk A/S | Purified PH neutral Rhizoctonia laccases and nucleic acids encoding same |
| US7390936B1 (en) | 1999-08-23 | 2008-06-24 | Sembiosys Genetics Inc. | Commercial production of chymosin in plants |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3650202T3 (de) * | 1985-08-29 | 2004-06-03 | Genencor International, Inc., South San Francisco | Expression von heterologen Polypeptiden in filamentösen Pilzen, Verfahren zu deren Herstellung und Vektoren zu deren Herstellung. |
| DK122686D0 (da) * | 1986-03-17 | 1986-03-17 | Novo Industri As | Fremstilling af proteiner |
| GB8610600D0 (en) * | 1986-04-30 | 1986-06-04 | Novo Industri As | Transformation of trichoderma |
-
1992
- 1992-03-20 AT AT92907324T patent/ATE123524T1/de not_active IP Right Cessation
- 1992-03-20 AU AU14309/92A patent/AU1430992A/en not_active Abandoned
- 1992-03-20 DE DE69202858T patent/DE69202858T2/de not_active Expired - Fee Related
- 1992-03-20 EP EP92907324A patent/EP0575462B1/de not_active Expired - Lifetime
- 1992-03-20 DK DK92907324.5T patent/DK0575462T3/da active
- 1992-03-20 JP JP4506830A patent/JPH06505873A/ja active Pending
- 1992-03-20 WO PCT/DK1992/000089 patent/WO1992016633A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| DE69202858D1 (de) | 1995-07-13 |
| EP0575462B1 (de) | 1995-06-07 |
| EP0575462A1 (de) | 1993-12-29 |
| WO1992016633A1 (en) | 1992-10-01 |
| DE69202858T2 (de) | 1996-02-22 |
| JPH06505873A (ja) | 1994-07-07 |
| DK0575462T3 (da) | 1995-11-06 |
| AU1430992A (en) | 1992-10-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |