ATE123527T1 - Trpr mutationen die wirksam sind in der expression von kleinen proteinen und peptiden. - Google Patents

Trpr mutationen die wirksam sind in der expression von kleinen proteinen und peptiden.

Info

Publication number: ATE123527T1
Authority: AT; Austria
Prior art keywords: lms; expression; trpr; mutations; peptides
Prior art date: 1991-04-05

Application number

AT92910290T

Other languages

English (en)

Inventor

Robert Alan Lepley

Original Assignee

Upjohn Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-04-05

Filing date

1992-03-27

Publication date

1995-06-15

1992-03-27 Application filed by Upjohn Co filed Critical Upjohn Co

1995-06-15 Application granted granted Critical

1995-06-15 Publication of ATE123527T1 publication Critical patent/ATE123527T1/de

Links

108090000623 proteins and genes Proteins 0.000 title abstract 5
102000004169 proteins and genes Human genes 0.000 title abstract 5
230000035772 mutation Effects 0.000 title 1
102000004196 processed proteins & peptides Human genes 0.000 title 1
108090000765 processed proteins & peptides Proteins 0.000 title 1
244000005700 microbiome Species 0.000 abstract 2
108700034853 E coli TRPR Proteins 0.000 abstract 1
241000588724 Escherichia coli Species 0.000 abstract 1
QIVBCDIJIAJPQS-VIFPVBQESA-N L-tryptophane Chemical compound C1=CC=C2C(C[C@H](N)C(O)=O)=CNC2=C1 QIVBCDIJIAJPQS-VIFPVBQESA-N 0.000 abstract 1
QIVBCDIJIAJPQS-UHFFFAOYSA-N Tryptophan Natural products C1=CC=C2C(CC(N)C(O)=O)=CNC2=C1 QIVBCDIJIAJPQS-UHFFFAOYSA-N 0.000 abstract 1
239000013604 expression vector Substances 0.000 abstract 1
230000000415 inactivating effect Effects 0.000 abstract 1
239000013612 plasmid Substances 0.000 abstract 1
101150006320 trpR gene Proteins 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
- C12N15/71—Expression systems using regulatory sequences derived from the trp-operon
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/65—Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2

Landscapes

Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Zoology (AREA)
Biotechnology (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
General Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
Wood Science & Technology (AREA)
Biophysics (AREA)
Biomedical Technology (AREA)
Physics & Mathematics (AREA)
Microbiology (AREA)
Plant Pathology (AREA)
Diabetes (AREA)
Endocrinology (AREA)
Toxicology (AREA)
Gastroenterology & Hepatology (AREA)
Medicinal Chemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Peptides Or Proteins (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

AT92910290T 1991-04-05 1992-03-27 Trpr mutationen die wirksam sind in der expression von kleinen proteinen und peptiden. ATE123527T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US68168891A	1991-04-05	1991-04-05
US83731392A	1992-02-18	1992-02-18

Publications (1)

Publication Number	Publication Date
ATE123527T1 true ATE123527T1 (de)	1995-06-15

Family

ID=27102710

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT92910290T ATE123527T1 (de)	1991-04-05	1992-03-27	Trpr mutationen die wirksam sind in der expression von kleinen proteinen und peptiden.

Country Status (8)

Country	Link
EP (1)	EP0578754B1 (de)
JP (1)	JPH06506118A (de)
AT (1)	ATE123527T1 (de)
AU (1)	AU1753092A (de)
DE (1)	DE69202859T2 (de)
DK (1)	DK0578754T3 (de)
ES (1)	ES2074887T3 (de)
WO (1)	WO1992017594A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPH10504971A (ja) *	1994-09-08	1998-05-19	カイロンコーポレイション	インスリン様増殖因子の改善された生産方法
GB2304718B (en) *	1995-09-05	2000-01-19	Degussa	The production of tryptophan by the bacterium escherichia coli
EP0966521A1 (de) *	1996-09-13	1999-12-29	Novo Nordisk Biotech, Inc.	Zellen mit dna-insertionsmutationenwelche veränderte mengen eines polypeptids produzieren

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DK108685A (da) *	1984-03-19	1985-09-20	Fujisawa Pharmaceutical Co	Vaekstfaktor i
CA1338664C (en) *	1985-04-10	1996-10-22	Cetus Oncology Corporation	Recombinant hosts

1992
- 1992-03-27 EP EP92910290A patent/EP0578754B1/de not_active Expired - Lifetime
- 1992-03-27 WO PCT/US1992/002235 patent/WO1992017594A1/en not_active Ceased
- 1992-03-27 AT AT92910290T patent/ATE123527T1/de not_active IP Right Cessation
- 1992-03-27 DE DE69202859T patent/DE69202859T2/de not_active Expired - Fee Related
- 1992-03-27 JP JP4509432A patent/JPH06506118A/ja active Pending
- 1992-03-27 DK DK92910290.3T patent/DK0578754T3/da active
- 1992-03-27 ES ES92910290T patent/ES2074887T3/es not_active Expired - Lifetime
- 1992-03-27 AU AU17530/92A patent/AU1753092A/en not_active Abandoned

Also Published As

Publication number	Publication date
DE69202859D1 (de)	1995-07-13
EP0578754A1 (de)	1994-01-19
ES2074887T3 (es)	1995-09-16
JPH06506118A (ja)	1994-07-14
EP0578754B1 (de)	1995-06-07
WO1992017594A1 (en)	1992-10-15
AU1753092A (en)	1992-11-02
DE69202859T2 (de)	1995-12-07
DK0578754T3 (da)	1995-11-06

Similar Documents

Publication	Publication Date	Title
FI943389L (fi)	1995-01-16	Bacillus-lajista saatu ksylanaasi, tällaisen ksylanaasin ja muiden proteiinien ekspressiovektori, niiden isäntäorganismit ja käyttö
ATE343635T1 (de)	2006-11-15	Bmp-11 zusammenstellungen
GB9223816D0 (en)	1993-01-06	Heat shock proteins and the treatment of tumours
ATE388165T1 (de)	2008-03-15	Menschliches cnp-gen und vorläuferprotein
ATE64619T1 (de)	1991-07-15	Menschliches apolipoprotein a1 sowie dessen variante, exprimiert in escherichia coli.
DK0832258T3 (da)	2002-08-12	Opstrøms aktivatorsekvenser og rekombinante promotorsekvenser, der er funktionelle i Yarrowia og vektorer indeholdende disse
ATE144284T1 (de)	1996-11-15	Verbesserte aktivierung von rekombinanten proteinen
ES2130219T3 (es)	1999-07-01	Moleculas para una administracion por iontoforesis.
BR9607583B1 (pt)	2009-12-01	plasmìdios procarióticos recombinantes.
DE69217144D1 (de)	1997-03-13	Regulator-DNA zur Gen-Expression
PT839194E (pt)	2006-08-31	Variantesda proteina p53 e utilizacoes terapeuticas.
DK1564293T3 (da)	2009-01-12	Nervetrådproteingenekspression og detektion af Alzheimers sygdom
DE69931507D1 (de)	2006-06-29	Interferon-beta fusionsproteine und deren verwendungen
EP0519218A3 (en)	1993-10-20	Hybrid-plasmid for the 38 kda antigen from m. tuberculosis, e. coli as host, the 38 kda antigen and a 33 kda protein
DE69202859D1 (de)	1995-07-13	TrpR MUTATIONEN DIE WIRKSAM SIND IN DER EXPRESSION VON KLEINEN PROTEINEN UND PEPTIDEN.
ATE123526T1 (de)	1995-06-15	Hochreprimierbare expressionskontrollsequenzen.
DE69127282D1 (de)	1997-09-18	Bakterielle wirte mit proteasemangel
RU95107705A (ru)	1997-03-27	Полипептид, рекомбинантный полинуклеотид, вакцина, применение вакцины
AU2323992A (en)	1993-03-02	Sequence for stabilizing proteins in bacteria protein stabilization sequence
KR950005991A (ko)	1995-03-20	섬자리공 항바이러스성 단백질(pip) 유전자 및 이를 발현하는 미생물
DE59108261D1 (de)	1996-11-14	Peptide des HIV-gag Proteins, ihre Herstellung und Verwendung
MY107451A (en)	1995-12-31	Cloning and expression of a rhoptry associated protein of p.falciparum
FR2777292B1 (fr)	2000-07-07	Nouvelles constructions pour l'expression controlee de proteines recombinantes dans des cellules procaryotes
SE8800981D0 (sv)	1988-03-17	A recombinant fusion protein, its use and a recombinant vector
ES2179060T3 (es)	2003-01-16	Plasmido derivado de lactobacillus delbrueckii sp.

Legal Events

Date	Code	Title	Description
1996-01-15	UEP	Publication of translation of european patent specification
1997-12-15	REN	Ceased due to non-payment of the annual fee