ATE124864T1 - Die wirkstoffabgabe steuerndes überzugsmaterial für lang wirksame formulierungen. - Google Patents

Die wirkstoffabgabe steuerndes überzugsmaterial für lang wirksame formulierungen.

Info

Publication number
ATE124864T1
ATE124864T1 AT90302287T AT90302287T ATE124864T1 AT E124864 T1 ATE124864 T1 AT E124864T1 AT 90302287 T AT90302287 T AT 90302287T AT 90302287 T AT90302287 T AT 90302287T AT E124864 T1 ATE124864 T1 AT E124864T1
Authority
AT
Austria
Prior art keywords
coating material
drug
long
controlls
active ingredients
Prior art date
Application number
AT90302287T
Other languages
English (en)
Inventor
Tadayoshi Ohmura
Muneo Fukui
Hiroshi Sugiura
Toshiharu Hosono
Atsushi Kajiyama
Satoru Yoneya
Original Assignee
Yamanouchi Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yamanouchi Pharma Co Ltd filed Critical Yamanouchi Pharma Co Ltd
Application granted granted Critical
Publication of ATE124864T1 publication Critical patent/ATE124864T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Paints Or Removers (AREA)
AT90302287T 1989-03-10 1990-03-05 Die wirkstoffabgabe steuerndes überzugsmaterial für lang wirksame formulierungen. ATE124864T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP5868489 1989-03-10

Publications (1)

Publication Number Publication Date
ATE124864T1 true ATE124864T1 (de) 1995-07-15

Family

ID=13091382

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90302287T ATE124864T1 (de) 1989-03-10 1990-03-05 Die wirkstoffabgabe steuerndes überzugsmaterial für lang wirksame formulierungen.

Country Status (19)

Country Link
US (1) US5028664A (de)
EP (1) EP0386967B1 (de)
JP (1) JPH037238A (de)
KR (1) KR0140985B1 (de)
CN (1) CN1045524A (de)
AT (1) ATE124864T1 (de)
AU (1) AU623233B2 (de)
CA (1) CA2011919A1 (de)
DD (2) DD292374A5 (de)
DE (1) DE69020758T2 (de)
DK (1) DK0386967T3 (de)
ES (1) ES2077023T3 (de)
FI (1) FI97690C (de)
GR (1) GR3017645T3 (de)
HU (1) HU204201B (de)
IE (1) IE68520B1 (de)
NO (1) NO301578B1 (de)
NZ (1) NZ232836A (de)
PT (1) PT93384B (de)

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GEP19971086B (en) * 1991-02-22 1997-12-02 Tillotts Pharma Ag Peroral Pharmaceutically Dispensed Form for Selective Introducing of the Medicine into the Intestine
GB9200607D0 (en) * 1992-01-13 1992-03-11 Ethical Pharma Ltd Pharmaceutical compositions containing nifedipine and process for the preparation thereof
US20030170290A1 (en) * 1993-06-16 2003-09-11 Shug Austin L. Delayed release carnitine
WO1995005168A1 (en) * 1993-08-19 1995-02-23 Shug Austin L Delayed release carnitine
DE9414066U1 (de) * 1994-08-31 1994-11-03 Röhm GmbH & Co. KG, 64293 Darmstadt Überzugs- und Bindemittel für Arzneiformen sowie damit hergestellte Arzneiform
NZ270078A (en) * 1994-12-06 1998-05-27 Bernard Charles Sherman Diltiazem hydrochloride formulation comprising beads with immediate, intermediate, and delayed release dissolution profiles
US5567441A (en) * 1995-03-24 1996-10-22 Andrx Pharmaceuticals Inc. Diltiazem controlled release formulation
WO1997004782A1 (en) * 1995-07-26 1997-02-13 Kyowa Hakko Kogyo Co., Ltd. Solid dispersion or solid dispersion preparation of xanthine derivatives
US6162463A (en) * 1997-05-01 2000-12-19 Dov Pharmaceutical Inc Extended release formulation of diltiazem hydrochloride
US6342611B1 (en) * 1997-10-10 2002-01-29 Cytovia, Inc. Fluorogenic or fluorescent reporter molecules and their applications for whole-cell fluorescence screening assays for capsases and other enzymes and the use thereof
AU2546399A (en) 1998-02-10 1999-08-30 Yoshitomi Pharmaceutical Industries, Ltd. Preparations with controlled release
EP1178780B1 (de) * 1999-05-20 2007-07-18 ELAN CORPORATION, Plc Multipartikuläre arzneizusammensetzungen mit gesteuerter wirkstoffabgabe enthaltend selektive inhibitoren der serotoninwiederaufnahme
EP1064938A1 (de) * 1999-06-28 2001-01-03 Sanofi-Synthelabo Pharmazeutische Dosierungsformen zur kontrollierte Wirkstoffabgabe mit mindenstens ein pulsierendem Zeitverlauf
DE60036874T2 (de) * 1999-09-02 2008-06-26 Nostrum Pharmaceuticals Inc. Pellet formulierung mit gesteuerter freisetzung
AR026148A1 (es) * 2000-01-21 2003-01-29 Osmotica Argentina S A Dispositivo osmotico con pasaje preformado que aumenta de tamano
WO2002066004A1 (fr) * 2001-02-23 2002-08-29 Mitsubishi Pharma Corporation Compositions a liberation controlee de medicament
KR20050044545A (ko) * 2001-11-21 2005-05-12 에자이 가부시키가이샤 산에 불안정한 생리활성 화합물을 함유하는 제제 조성물및 그 제법
SE0201110D0 (sv) * 2002-04-12 2002-04-12 Astrazeneca Ab New film coating
US20090208579A1 (en) * 2004-12-27 2009-08-20 Eisai R & D Management Co., Ltd. Matrix Type Sustained-Release Preparation Containing Basic Drug or Salt Thereof, and Method for Manufacturing the Same
US8481565B2 (en) 2004-12-27 2013-07-09 Eisai R&D Management Co., Ltd. Method for stabilizing anti-dementia drug
US20060246003A1 (en) * 2004-12-27 2006-11-02 Eisai Co. Ltd. Composition containing anti-dementia drug
CN100398122C (zh) * 2005-01-28 2008-07-02 北京北大药业有限公司 一种治疗颈、腰椎病中药的肠溶包衣组合物
KR101571179B1 (ko) * 2008-01-10 2015-11-23 에보니크 룀 게엠베하 증가된 맥동성 활성 물질 방출을 갖는 코팅된 제약학적 또는 건강기능성 제제
JP2011509266A (ja) * 2008-01-10 2011-03-24 エボニック レーム ゲゼルシャフト ミット ベシュレンクテル ハフツング 活性物質の制御放出が促進された、コーティングされた医薬製剤もしくはニュートラシューティカル製剤
US9028878B2 (en) 2009-02-03 2015-05-12 Microbion Corporation Bismuth-thiols as antiseptics for biomedical uses, including treatment of bacterial biofilms and other uses
US9408393B2 (en) 2010-02-03 2016-08-09 Microbion Corporation Bismuth-thiols as antiseptics for agricultural, industrial and other uses
CN102341105B (zh) 2009-02-03 2014-09-17 微生物公司 用作上皮组织、急性和慢性伤口、细菌生物被膜和其他适应症的抗菌剂的铋硫醇
JP7564101B2 (ja) 2018-07-31 2024-10-08 マイクロビオン コーポレーション ビスマスチオール組成物及び使用方法
MX2021001276A (es) 2018-07-31 2021-07-15 Microbion Corp Composiciones de bismuto-tiol y metodos para tratar heridas.
WO2022029938A1 (ja) * 2020-08-05 2022-02-10 マルホ株式会社 皮膚用組成物

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3236914A (en) * 1959-05-12 1966-02-22 Canadian Ind Method for rendering polymers compatible
US3300429A (en) * 1963-06-17 1967-01-24 Rohm & Haas Aqueous polymeric blends containing ureido monomer
US3369009A (en) * 1964-12-10 1968-02-13 Hercules Inc Azidoformate-containing copolymers
US3641237A (en) * 1970-09-30 1972-02-08 Nat Patent Dev Corp Zero order release constant elution rate drug dosage
US4065523A (en) * 1975-11-24 1977-12-27 Rohm And Haas Company Process for increasing molecular weight of a polymer
US4082705A (en) * 1976-02-05 1978-04-04 Johnson & Johnson Pressure sensitive adhesive compositions
GB2046275A (en) * 1979-03-27 1980-11-12 American Cyanamid Co Granulation and drying aids for polymeric gels
SE8003805L (sv) * 1980-05-21 1981-11-22 Haessle Ab En farmaceutisk beredning med forbettrade utlosningsegenskap
US4539199A (en) * 1981-01-14 1985-09-03 Egyt Gyogyszervegyeszeti Gyar Sustained release pharmaceutical compositions
US4758437A (en) * 1981-12-23 1988-07-19 Yamanouchi Pharmaceutical Co., Ltd. Composition for long acting nicardipine preparation and process of producing the composition
JPS6051106A (ja) * 1983-08-31 1985-03-22 Yamanouchi Pharmaceut Co Ltd 塩酸アモスラロ−ル持続性製剤
JPS60240747A (ja) * 1984-05-15 1985-11-29 Showa Denko Kk 架橋性組成物及びエステル架橋型重合体
JPS62126122A (ja) * 1985-11-27 1987-06-08 Showa Shinyaku Kk 表面コ−テイングされたイブプロフエン顆粒の製法
IL77186A0 (en) * 1985-11-29 1986-04-29 Touitou Elka Pharmaceutical insulin composition
JP2667162B2 (ja) * 1986-11-04 1997-10-27 日本製紙株式会社 インクジエツト記録用シート
SE460946B (sv) * 1987-03-16 1989-12-11 Lejus Medical Ab En multipel-unit-dos komposition av kinidinglukonat

Also Published As

Publication number Publication date
NO901116L (no) 1990-09-11
FI97690B (fi) 1996-10-31
CN1045524A (zh) 1990-09-26
HU204201B (en) 1991-12-30
EP0386967B1 (de) 1995-07-12
IE900862L (en) 1990-09-10
EP0386967A2 (de) 1990-09-12
ES2077023T3 (es) 1995-11-16
HU901380D0 (en) 1990-05-28
PT93384A (pt) 1990-11-07
KR0140985B1 (ko) 1998-06-01
HUT53813A (en) 1990-12-28
DK0386967T3 (da) 1995-11-20
CA2011919A1 (en) 1990-09-10
DD292374A5 (de) 1991-08-01
NZ232836A (en) 1991-06-25
PT93384B (pt) 1996-03-29
IE68520B1 (en) 1996-06-26
NO301578B1 (no) 1997-11-17
DE69020758T2 (de) 1995-12-07
FI97690C (fi) 1997-02-10
JPH037238A (ja) 1991-01-14
GR3017645T3 (en) 1996-01-31
AU623233B2 (en) 1992-05-07
NO901116D0 (no) 1990-03-09
EP0386967A3 (de) 1991-04-03
DE69020758D1 (de) 1995-08-17
AU5122790A (en) 1990-09-13
US5028664A (en) 1991-07-02
DD298205A5 (de) 1992-02-13
KR900013943A (ko) 1990-10-22
FI901195A0 (fi) 1990-03-09

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee