ATE125799T1 - Nasale verabreichung von benzodiazepinhypnotika. - Google Patents

Nasale verabreichung von benzodiazepinhypnotika.

Info

Publication number
ATE125799T1
ATE125799T1 AT89911428T AT89911428T ATE125799T1 AT E125799 T1 ATE125799 T1 AT E125799T1 AT 89911428 T AT89911428 T AT 89911428T AT 89911428 T AT89911428 T AT 89911428T AT E125799 T1 ATE125799 T1 AT E125799T1
Authority
AT
Austria
Prior art keywords
nasal administration
benzodiazepine hypnotics
benzodiazepine
nasal
hypnotics
Prior art date
Application number
AT89911428T
Other languages
English (en)
Inventor
Arthur H Goldberg
Original Assignee
Ribogene Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22925038&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE125799(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ribogene Inc filed Critical Ribogene Inc
Application granted granted Critical
Publication of ATE125799T1 publication Critical patent/ATE125799T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Otolaryngology (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT89911428T 1988-09-16 1989-09-08 Nasale verabreichung von benzodiazepinhypnotika. ATE125799T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/245,031 US4950664A (en) 1988-09-16 1988-09-16 Nasal administration of benzodiazepine hypnotics

Publications (1)

Publication Number Publication Date
ATE125799T1 true ATE125799T1 (de) 1995-08-15

Family

ID=22925038

Family Applications (1)

Application Number Title Priority Date Filing Date
AT89911428T ATE125799T1 (de) 1988-09-16 1989-09-08 Nasale verabreichung von benzodiazepinhypnotika.

Country Status (13)

Country Link
US (1) US4950664A (de)
EP (1) EP0386232B2 (de)
JP (1) JP2729525B2 (de)
KR (1) KR920005965B1 (de)
AT (1) ATE125799T1 (de)
AU (1) AU640618B2 (de)
CA (1) CA1336502C (de)
DE (1) DE68923697T3 (de)
DK (1) DK175710B1 (de)
FI (1) FI902421A0 (de)
IL (1) IL91656A0 (de)
NZ (1) NZ230653A (de)
WO (1) WO1990002737A1 (de)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
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USRE36744E (en) * 1988-09-16 2000-06-20 Ribogene, Inc. Nasal administration of benzodiazepine hypnotics
AU7880991A (en) * 1990-05-10 1991-11-27 Novo Nordisk A/S A pharmaceutical preparation containing n-glycofurols and n-ethylene glycols
US5166202A (en) * 1990-09-19 1992-11-24 Trustees Of The University Of Pennsylvania Method for the treatment of panic disorder
CA2055308A1 (en) * 1990-11-29 1992-05-30 F. Hoffmann-La Roche Ag Imidazobenzodiazepine for the treatment of sleep disorders
US5679580A (en) * 1994-03-09 1997-10-21 Midwest Research Institute Rapid evaporation method for analysis
GB9409778D0 (en) 1994-05-16 1994-07-06 Dumex Ltd As Compositions
ATE210447T1 (de) * 1994-10-14 2001-12-15 Glaxo Wellcome Spa Verwendung von cck-b rezeptor antagonisten zur behandlung von schlafstörungen
US6552024B1 (en) 1999-01-21 2003-04-22 Lavipharm Laboratories Inc. Compositions and methods for mucosal delivery
AU778896B2 (en) 1999-07-26 2004-12-23 Sk Biopharmaceuticals Co., Ltd. Transnasal anticonvulsive compositions and modulated process
EP1246817B1 (de) * 1999-12-30 2004-06-23 H. Lundbeck A/S 4-phenyl-1-piperazinyl, -piperidinyl und -tetrahydropyridyl-derivate
US6610271B2 (en) * 2000-05-10 2003-08-26 University Of Kentucky Research Foundation System and method for intranasal administration of lorazepam
US20060083691A1 (en) * 2000-05-10 2006-04-20 Wermeling Daniel P Intranasal opioid compositions, delivery devices and methods of using same
US20040115133A1 (en) * 2000-05-10 2004-06-17 Wermeling Daniel P. Intranasal opioid compositions
EP1315533A4 (de) * 2000-08-15 2007-06-27 Univ Kentucky Res Found Programmierbare mehrdosenvorrichtung für intranasale medikamentenverabreichung
US20040176359A1 (en) * 2001-02-20 2004-09-09 University Of Kentucky Research Foundation Intranasal Benzodiazepine compositions
WO2002094218A2 (en) 2001-05-24 2002-11-28 Alexza Molecular Delivery Corporation Delivery of alprazolam, estazolam, midazolam or triazolam through an inhalation route
US7645442B2 (en) 2001-05-24 2010-01-12 Alexza Pharmaceuticals, Inc. Rapid-heating drug delivery article and method of use
US7766013B2 (en) 2001-06-05 2010-08-03 Alexza Pharmaceuticals, Inc. Aerosol generating method and device
US7585493B2 (en) 2001-05-24 2009-09-08 Alexza Pharmaceuticals, Inc. Thin-film drug delivery article and method of use
US7090830B2 (en) 2001-05-24 2006-08-15 Alexza Pharmaceuticals, Inc. Drug condensation aerosols and kits
US7458374B2 (en) 2002-05-13 2008-12-02 Alexza Pharmaceuticals, Inc. Method and apparatus for vaporizing a compound
US20070122353A1 (en) 2001-05-24 2007-05-31 Hale Ron L Drug condensation aerosols and kits
JP2005503425A (ja) 2001-05-24 2005-02-03 アレックザ モレキュラー デリヴァリー コーポレイション 所定の吸入ルートによる薬剤エステルの送出
US7550133B2 (en) 2002-11-26 2009-06-23 Alexza Pharmaceuticals, Inc. Respiratory drug condensation aerosols and methods of making and using them
US20040105818A1 (en) 2002-11-26 2004-06-03 Alexza Molecular Delivery Corporation Diuretic aerosols and methods of making and using them
US7913688B2 (en) 2002-11-27 2011-03-29 Alexza Pharmaceuticals, Inc. Inhalation device for producing a drug aerosol
US7138107B2 (en) * 2003-02-18 2006-11-21 Compellis Pharmaceuticals Inhibition of olfactory neurosensory function to treat eating disorders and obesity
US20040241100A1 (en) * 2003-03-17 2004-12-02 Fabre Kramer Pharmaceutical, Inc. Nasally administrable compositions of zolpidem and methods of use
JP2006527764A (ja) * 2003-06-17 2006-12-07 エスケー コーポレイション ジアゼパムを含有する経鼻マイクロエマルジョン
GB0400804D0 (en) * 2004-01-14 2004-02-18 Innoscience Technology Bv Pharmaceutical compositions
US7540286B2 (en) 2004-06-03 2009-06-02 Alexza Pharmaceuticals, Inc. Multiple dose condensation aerosol devices and methods of forming condensation aerosols
EP2246086A3 (de) 2004-08-12 2012-11-21 Alexza Pharmaceuticals, Inc. Aerosolverabreichungsvorrichtung mit Schlag gezündete Heizeinheit
US20060039869A1 (en) * 2004-08-17 2006-02-23 Daniel Wermeling Intranasal delivery of antipsychotic drugs
TW200824693A (en) * 2006-08-28 2008-06-16 Jazz Pharmaceuticals Inc Pharmaceutical compositions of clonazepam and methods of use thereof
US7745430B2 (en) * 2006-11-15 2010-06-29 Sk Holdings Co., Ltd. Transnasal anticonvulsive pharmaceutical composition
US20080275030A1 (en) 2007-01-19 2008-11-06 Sveinbjorn Gizurarson Methods and Compositions for the Delivery of a Therapeutic Agent
EP2121088B1 (de) 2007-03-09 2016-07-13 Alexza Pharmaceuticals, Inc. Erhitzungseinheit zur verwendung in einer arzneimittelabgabevorrichtung
TW200922635A (en) * 2007-08-31 2009-06-01 Archimedes Dev Ltd Non-aqueous pharmaceutical compositions
KR101517415B1 (ko) 2008-05-14 2015-05-07 에스케이바이오팜 주식회사 난용성 항경련제를 함유하는 경비 항경련성 약학 조성물
US20140128379A1 (en) * 2011-04-01 2014-05-08 Cpex Pharmaceuticals, Inc. Nasal formulations of benzodiazepine
JP2016171366A (ja) * 2015-03-11 2016-09-23 キヤノン株式会社 画像読取装置
JP2019513796A (ja) * 2016-04-14 2019-05-30 パイオン ユーケー リミティド 経口吸入及び経鼻用ベンゾジアゼピン
US12214118B2 (en) 2018-02-02 2025-02-04 Alexza Pharmaceuticals, Inc. Electrical condensation aerosol device

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2906265A (en) † 1957-09-03 1959-09-29 Maryland Devices Inc Nasal adaptor for valved dispenser
US4153689A (en) † 1975-06-13 1979-05-08 Takeda Chemical Industries, Ltd. Stable insulin preparation for nasal administration
GB1604644A (en) * 1977-07-22 1981-12-09 Wellcome Found Biologically active pentapeptide amides
US4284648A (en) * 1979-08-03 1981-08-18 The University Of Kentucky Research Foundation Nasal administration of propranolol
US4381773A (en) † 1980-06-23 1983-05-03 Schering Corporation Method and nozzle for nasal vaccination of immature mammals
US4428883A (en) * 1981-03-06 1984-01-31 The University Of Kentucky Research Foundation Novel method of administering β-blockers and novel dosage forms containing same
FR2568773B1 (fr) * 1984-08-10 1989-03-03 Sandoz Lab Nouvelles compositions pharmaceutiques administrables par voie nasale
JPS6160620A (ja) * 1984-09-03 1986-03-28 Teijin Ltd ピログルタミン酸エステル類を含有する医薬品組成物
JPH0710771B2 (ja) * 1984-10-23 1995-02-08 ナステツク フア−マス−テイカル カンパニ−、インコ−ポレイテツド 抗吐き気および抗嘔吐薬剤の新規な投与組成物
JPS61267528A (ja) † 1984-11-26 1986-11-27 Yamanouchi Pharmaceut Co Ltd 吸収促進剤を含有するカルシトニン経鼻剤
WO1987005210A1 (fr) * 1986-03-10 1987-09-11 Kurt Burghart Produit pharmaceutique et son procede de preparation
US4786647A (en) * 1986-06-30 1988-11-22 University Of Florida Method for eliciting anxiolysis

Also Published As

Publication number Publication date
DK120390A (da) 1990-05-15
AU640618B2 (en) 1993-09-02
DE68923697D1 (de) 1995-09-07
DK175710B1 (da) 2005-01-31
EP0386232A1 (de) 1990-09-12
CA1336502C (en) 1995-08-01
DE68923697T3 (de) 2001-04-05
EP0386232B1 (de) 1995-08-02
JP2729525B2 (ja) 1998-03-18
DE68923697T2 (de) 1996-01-25
AU4349989A (en) 1990-04-02
WO1990002737A1 (en) 1990-03-22
KR920005965B1 (ko) 1992-07-25
IL91656A0 (en) 1990-04-29
NZ230653A (en) 1991-05-28
KR900701252A (ko) 1990-12-01
FI902421A7 (fi) 1990-05-15
US4950664A (en) 1990-08-21
DK120390D0 (da) 1990-05-15
JPH03501390A (ja) 1991-03-28
FI902421A0 (fi) 1990-05-15
EP0386232B2 (de) 2000-09-06
EP0386232A4 (en) 1991-03-13

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Legal Events

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UEP Publication of translation of european patent specification
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee