ATE127231T1 - Verfahren zur bestimmung eines oder mehrerer analyte durch anwendung verschiedene typen von partikeln, welche durchflusszytometrisch unterschieden sind. - Google Patents

Verfahren zur bestimmung eines oder mehrerer analyte durch anwendung verschiedene typen von partikeln, welche durchflusszytometrisch unterschieden sind.

Info

Publication number
ATE127231T1
ATE127231T1 AT89905720T AT89905720T ATE127231T1 AT E127231 T1 ATE127231 T1 AT E127231T1 AT 89905720 T AT89905720 T AT 89905720T AT 89905720 T AT89905720 T AT 89905720T AT E127231 T1 ATE127231 T1 AT E127231T1
Authority
AT
Austria
Prior art keywords
particles
analyte
different
binding
flow cytometer
Prior art date
Application number
AT89905720T
Other languages
English (en)
Inventor
Tore Lindmo
Original Assignee
Sinvent As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sinvent As filed Critical Sinvent As
Application granted granted Critical
Publication of ATE127231T1 publication Critical patent/ATE127231T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/808—Optical sensing apparatus
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/81—Packaged device or kit
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/962—Prevention or removal of interfering materials or reactants or other treatment to enhance results, e.g. determining or preventing nonspecific binding
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/80—Fluorescent dyes, e.g. rhodamine
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/805—Optical property

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Dispersion Chemistry (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Mechanical Treatment Of Semiconductor (AREA)
AT89905720T 1988-05-11 1989-05-10 Verfahren zur bestimmung eines oder mehrerer analyte durch anwendung verschiedene typen von partikeln, welche durchflusszytometrisch unterschieden sind. ATE127231T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NO882067A NO164622C (no) 1988-05-11 1988-05-11 Binaer immunometrisk partikkelbasert metode for maaling av spesifikke serum-antigener ved hjelp av vaeskestroemsmikrofotometri og et ferdigpreparert maaloppsett derav.

Publications (1)

Publication Number Publication Date
ATE127231T1 true ATE127231T1 (de) 1995-09-15

Family

ID=19890879

Family Applications (1)

Application Number Title Priority Date Filing Date
AT89905720T ATE127231T1 (de) 1988-05-11 1989-05-10 Verfahren zur bestimmung eines oder mehrerer analyte durch anwendung verschiedene typen von partikeln, welche durchflusszytometrisch unterschieden sind.

Country Status (9)

Country Link
US (1) US5585241A (de)
EP (1) EP0413741B1 (de)
JP (1) JP2742953B2 (de)
AT (1) ATE127231T1 (de)
AU (1) AU3565889A (de)
CA (1) CA1335238C (de)
DE (1) DE68924064T2 (de)
NO (1) NO164622C (de)
WO (1) WO1989011101A1 (de)

Families Citing this family (121)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH03225277A (ja) * 1990-01-31 1991-10-04 Fujirebio Inc 多項目の免疫化学的測定法
US5286452A (en) * 1991-05-20 1994-02-15 Sienna Biotech, Inc. Simultaneous multiple assays
US5329461A (en) * 1992-07-23 1994-07-12 Acrogen, Inc. Digital analyte detection system
TW239881B (de) * 1992-12-22 1995-02-01 Sienna Biotech Inc
US6200820B1 (en) * 1992-12-22 2001-03-13 Sienna Biotech, Inc. Light scatter-based immunoassay
US6401267B1 (en) * 1993-09-27 2002-06-11 Radoje Drmanac Methods and compositions for efficient nucleic acid sequencing
GB9326379D0 (en) * 1993-12-23 1994-02-23 Sinvent As Method of assay
GB9326238D0 (en) * 1993-12-23 1994-02-23 Sinvent As Method of assay
GB2300914B (en) * 1995-04-28 1998-04-29 Tepnel Medical Ltd Analytical device
WO1997014028A2 (en) * 1995-10-11 1997-04-17 Luminex Corporation Multiplexed analysis of clinical specimens apparatus and method
US5981180A (en) * 1995-10-11 1999-11-09 Luminex Corporation Multiplexed analysis of clinical specimens apparatus and methods
US7144119B2 (en) 1996-04-25 2006-12-05 Bioarray Solutions Ltd. System and method for programmable illumination pattern generation
US7041510B2 (en) 1996-04-25 2006-05-09 Bioarray Solutions Ltd. System and method for programmable illumination pattern generation
US6387707B1 (en) 1996-04-25 2002-05-14 Bioarray Solutions Array Cytometry
US6586193B2 (en) * 1996-04-25 2003-07-01 Genicon Sciences Corporation Analyte assay using particulate labels
ES2288760T3 (es) 1996-04-25 2008-01-16 Bioarray Solutions Ltd. Ensamblaje electrocinetico controlado por luz de particulas proximas a superficies.
US6958245B2 (en) 1996-04-25 2005-10-25 Bioarray Solutions Ltd. Array cytometry
CA2189486A1 (en) * 1996-11-04 1998-05-04 Yves St-Pierre Analysis of enzyme activity using immobilized fluorescence-labeled substrates
US20030027126A1 (en) 1997-03-14 2003-02-06 Walt David R. Methods for detecting target analytes and enzymatic reactions
US6023540A (en) * 1997-03-14 2000-02-08 Trustees Of Tufts College Fiber optic sensor with encoded microspheres
US6327410B1 (en) 1997-03-14 2001-12-04 The Trustees Of Tufts College Target analyte sensors utilizing Microspheres
US7622294B2 (en) 1997-03-14 2009-11-24 Trustees Of Tufts College Methods for detecting target analytes and enzymatic reactions
US6406845B1 (en) 1997-05-05 2002-06-18 Trustees Of Tuft College Fiber optic biosensor for selectively detecting oligonucleotide species in a mixed fluid sample
EP0878552A1 (de) 1997-05-13 1998-11-18 Erasmus Universiteit Rotterdam Molekularer Nachweis von chromosomalen Veränderungen
US6686165B2 (en) * 1997-05-20 2004-02-03 Erasmus Universiteit Rotterdam Recognition of tumor-specific gene products in cancer
WO1998053093A1 (en) 1997-05-23 1998-11-26 Bioarray Solutions Llc Color-encoding and in-situ interrogation of matrix-coupled chemical compounds
CA2244326C (en) 1997-08-11 2006-03-28 Shinichi Eda Microparticle enhanced light scattering agglutination assay and microparticle reagents therefor
AU8908198A (en) * 1997-08-15 1999-03-08 Hyseq, Inc. Methods and compositions for detection or quantification of nucleic acid species
US7115884B1 (en) 1997-10-06 2006-10-03 Trustees Of Tufts College Self-encoding fiber optic sensor
US7348181B2 (en) 1997-10-06 2008-03-25 Trustees Of Tufts College Self-encoding sensor with microspheres
US6180340B1 (en) * 1997-10-31 2001-01-30 Gen-Probe Incorporated Extended dynamic range assays
EP0965044B1 (de) 1997-11-18 2003-03-19 Bio-Rad Laboratories, Inc. Multiplex-zufluss-immunotest mit magnetischen teilchen als festphase
US6210910B1 (en) 1998-03-02 2001-04-03 Trustees Of Tufts College Optical fiber biosensor array comprising cell populations confined to microcavities
US6455263B2 (en) 1998-03-24 2002-09-24 Rigel Pharmaceuticals, Inc. Small molecule library screening using FACS
AU3516899A (en) 1998-05-04 1999-11-23 Dako A/S Method and probes for the detection of chromosome aberrations
US7060431B2 (en) 1998-06-24 2006-06-13 Illumina, Inc. Method of making and decoding of array sensors with microspheres
US6284472B1 (en) * 1998-10-05 2001-09-04 Dade Behring Inc. Method for extending the range of an immunoassay
US6429027B1 (en) 1998-12-28 2002-08-06 Illumina, Inc. Composite arrays utilizing microspheres
US7612020B2 (en) 1998-12-28 2009-11-03 Illumina, Inc. Composite arrays utilizing microspheres with a hybridization chamber
US6846460B1 (en) 1999-01-29 2005-01-25 Illumina, Inc. Apparatus and method for separation of liquid phases of different density and for fluorous phase organic syntheses
US20030096433A1 (en) * 1999-03-03 2003-05-22 Evotec Analytical Systems Gmbh Homogeneous fluorescence assay
US20060275782A1 (en) 1999-04-20 2006-12-07 Illumina, Inc. Detection of nucleic acid reactions on bead arrays
US6355431B1 (en) 1999-04-20 2002-03-12 Illumina, Inc. Detection of nucleic acid amplification reactions using bead arrays
US6544732B1 (en) 1999-05-20 2003-04-08 Illumina, Inc. Encoding and decoding of array sensors utilizing nanocrystals
EP2360270B1 (de) 1999-05-20 2016-11-09 Illumina, Inc. Kombinatorische Entschlüsselung von Zufallsnukleinsäurearrays
US8481268B2 (en) 1999-05-21 2013-07-09 Illumina, Inc. Use of microfluidic systems in the detection of target analytes using microsphere arrays
US8080380B2 (en) 1999-05-21 2011-12-20 Illumina, Inc. Use of microfluidic systems in the detection of target analytes using microsphere arrays
KR20000074881A (ko) * 1999-05-26 2000-12-15 황승용 마이크로웰을 이용한 디엔에이 돌연변이의 확인방법 및 키트
US6383740B2 (en) * 1999-07-30 2002-05-07 Bioergonomics, Inc. Methods for simultaneously detecting both members of a binding pair
ATE542916T1 (de) 1999-08-18 2012-02-15 Illumina Inc Methoden zur erzeugung von oligonukleotidlösungen
EP1212599A2 (de) 1999-08-30 2002-06-12 Illumina, Inc. Verfahren zur verbesserung des signals einer sensorarray
US7611869B2 (en) 2000-02-07 2009-11-03 Illumina, Inc. Multiplexed methylation detection methods
AU3806701A (en) 2000-02-07 2001-08-14 Illumina Inc Nucleic acid detection methods using universal priming
US7361488B2 (en) 2000-02-07 2008-04-22 Illumina, Inc. Nucleic acid detection methods using universal priming
US6913884B2 (en) 2001-08-16 2005-07-05 Illumina, Inc. Compositions and methods for repetitive use of genomic DNA
US7582420B2 (en) 2001-07-12 2009-09-01 Illumina, Inc. Multiplex nucleic acid reactions
AU2001238068A1 (en) 2000-02-07 2001-08-14 Illumina, Inc. Nucleic acid detection methods using universal priming
US6770441B2 (en) 2000-02-10 2004-08-03 Illumina, Inc. Array compositions and methods of making same
ATE412774T1 (de) 2000-02-16 2008-11-15 Illumina Inc Parallele genotypisierung mehrerer patientenproben
WO2001096604A2 (en) * 2000-06-12 2001-12-20 Genicon Sciences Corporation Assay for genetic polymorphisms using scattered light detectable labels
US9709559B2 (en) 2000-06-21 2017-07-18 Bioarray Solutions, Ltd. Multianalyte molecular analysis using application-specific random particle arrays
US7057704B2 (en) 2000-09-17 2006-06-06 Bioarray Solutions Ltd. System and method for programmable illumination pattern generation
US20030175994A1 (en) * 2000-10-05 2003-09-18 Yoram Palti Geometrically efficient particle agglutination, particularly to detect low affinity
US20030045005A1 (en) 2000-10-17 2003-03-06 Michael Seul Light-controlled electrokinetic assembly of particles near surfaces
JP2005507489A (ja) 2001-02-23 2005-03-17 ジェニコン サイエンスィズ コーポレーション 検体分析において拡張ダイナミックレンジを提供する方法
CA2441206A1 (en) 2001-03-19 2002-09-26 Gyros Ab Characterization of reaction variables
US7262063B2 (en) 2001-06-21 2007-08-28 Bio Array Solutions, Ltd. Directed assembly of functional heterostructures
US20030013083A1 (en) * 2001-07-16 2003-01-16 Tsai Tenlin S. Particle analysis as a detection system for particle-enhanced assays
US7479630B2 (en) 2004-03-25 2009-01-20 Bandura Dmitry R Method and apparatus for flow cytometry linked with elemental analysis
CA2459320C (en) 2001-09-06 2016-07-05 Genomic Profiling Systems, Inc. Rapid detection of replicating cells
US7179658B2 (en) * 2001-09-06 2007-02-20 Beckman Coulter, Inc. Particle based homogeneous assays using capillary electrophoresis with laser-induced fluorescence detection
US20050164261A1 (en) * 2001-10-09 2005-07-28 Chandler Don J. Multiplexed analysis of clinical specimens apparatus and methods
US8148171B2 (en) 2001-10-09 2012-04-03 Luminex Corporation Multiplexed analysis of clinical specimens apparatus and methods
CA2497740C (en) 2001-10-15 2011-06-21 Bioarray Solutions, Ltd. Multiplexed analysis of polymorphic loci by probe elongation-mediated detection
US6838289B2 (en) * 2001-11-14 2005-01-04 Beckman Coulter, Inc. Analyte detection system
US6551788B1 (en) * 2001-11-28 2003-04-22 Beckman Coulter, Inc. Particle-based ligand assay with extended dynamic range
DE60226641D1 (de) * 2001-12-03 2008-06-26 Amgen Fremont Inc Antikörperkategorisierung auf der grundlage von bindungseigenschaften
ATE374944T1 (de) 2001-12-03 2007-10-15 Abgenix Inc Identifizierung hochaffiner moleküle durch screening mit begrenzter verdünnung
JP2005512043A (ja) * 2001-12-03 2005-04-28 アブジェニックス・インコーポレーテッド 治療剤産物の発見
US20030166303A1 (en) * 2001-12-21 2003-09-04 David Peritt Novel screening method for molecular antagonist using flow-cytometry
WO2003064998A2 (en) 2002-01-31 2003-08-07 Burstein Technologies, Inc. Method for triggering through disc grooves and related optical analysis discs and system
US20030153011A1 (en) * 2002-02-08 2003-08-14 Bell Michael L. Methods and reagents for conducting multiplexed assays of multiple analytes
WO2003069333A1 (en) 2002-02-14 2003-08-21 Illumina, Inc. Automated information processing in randomly ordered arrays
US7247489B2 (en) * 2002-03-11 2007-07-24 Auburn University Ion-detecting microspheres and methods of use thereof
EP1365240B1 (de) * 2002-05-22 2006-09-13 Sysmex Corporation Immunologische Verfahren, Vorrichtungen und Reagenzien
DK2204654T3 (da) * 2002-08-13 2013-03-11 N Dia Inc Anordninger og fremgangsmåder til detektering af fostervand i vaginalsekretioner
US20040038318A1 (en) * 2002-08-23 2004-02-26 Bell Michael L. Creatine kinase isoenzyme determination in multiplexed assays
WO2004047007A1 (en) 2002-11-15 2004-06-03 Bioarray Solutions, Ltd. Analysis, secure access to, and transmission of array images
CA2521904A1 (en) * 2003-04-01 2004-10-21 Proactive Oral Solutions, Inc. Caries risk test for predicting and assessing the risk of disease
JP4564959B2 (ja) 2003-09-22 2010-10-20 バイオアレイ ソリューションズ リミテッド 生体分子に共有結合できる、複数の官能基を持つ表面固定化高分子電解質
US7592187B2 (en) * 2003-10-15 2009-09-22 Reverse Proteomics Research Institute Co., Ltd. Method of calibrating ligand specificity
US7563569B2 (en) 2003-10-28 2009-07-21 Michael Seul Optimization of gene expression analysis using immobilized capture probes
US7410808B1 (en) 2003-12-08 2008-08-12 Charm Sciences, Inc. Method and assay for detection of residues
US20050148005A1 (en) * 2003-12-12 2005-07-07 Pasha Emadi-Konjin Dye solubilization binding assay
DE102004023402A1 (de) * 2004-05-12 2005-12-08 Roche Diagnostics Gmbh Verfahren zur Erhöhung des dynamischen Messbereichs von auf spezifischen Bindereaktionen basierenden, insbesondere immunologischen Testelementen
US7848889B2 (en) 2004-08-02 2010-12-07 Bioarray Solutions, Ltd. Automated analysis of multiplexed probe-target interaction patterns: pattern matching and allele identification
GB2420850A (en) * 2004-12-03 2006-06-07 Orion Diagnostica Oy Particle based binding assay
US7723127B2 (en) 2005-03-03 2010-05-25 Novx Systems Inc. Immunoassay with extended dynamic range
US20060240444A1 (en) * 2005-04-21 2006-10-26 Peiguo Chu Detection methods
CA2623408C (en) 2005-09-26 2014-04-01 Rapid Micro Biosystems, Inc. Cassette containing growth medium
US8101368B2 (en) * 2006-02-13 2012-01-24 Dvs Sciences Inc. Quantitation of cellular DNA and cell numbers using element labeling
WO2008058004A2 (en) * 2006-11-02 2008-05-15 Winnik Mitchell A Particles containing detectable elemental code
AU2009296526B2 (en) 2008-09-24 2015-11-19 First Light Diagnostics, Inc. Method for detecting analytes
US20110151435A1 (en) 2009-12-17 2011-06-23 Abaxis, Inc. Novel assays for detecting analytes in samples and kits and compositions related thereto
EP2566949B1 (de) 2010-05-06 2023-02-15 Charm Sciences, Inc. Lesegerät-inkubator
WO2012049316A1 (en) 2010-10-15 2012-04-19 Olink Ab Dynamic range methods
DK3327110T3 (en) 2011-11-07 2020-04-27 Rapid Micro Biosystems Inc Kassette til sterilitetstest
CA2804843C (en) 2012-02-06 2021-02-02 Ortho-Clinical Diagnostics, Inc. Multiple time windows for extending the range of an assay
EP2839021B1 (de) 2012-04-16 2022-02-23 Rapid Micro Biosystems, Inc. Zellkultivierungsvorrichtung
CA2897053C (en) 2013-01-02 2020-10-13 N-Dia, Inc. Methods for predicting time-to-delivery in pregnant women
US9157910B2 (en) 2013-03-15 2015-10-13 Abbott Laboratories Assay with increased dynamic range
US9005901B2 (en) 2013-03-15 2015-04-14 Abbott Laboratories Assay with internal calibration
US20170176419A1 (en) 2014-03-26 2017-06-22 Siemens Healthcare Diagnostics Inc. Luminescent oxygen channeling immunoassay utilizing three antibodies and methods of production and use thereof
US11119102B1 (en) 2016-02-16 2021-09-14 Charm Sciences, Inc. Test device, method, and assembly
US10935555B2 (en) 2016-12-22 2021-03-02 Qiagen Sciences, Llc Determining candidate for induction of labor
US10656164B2 (en) 2016-12-22 2020-05-19 Qiagen Sciences, Llc Screening asymptomatic pregnant woman for preterm birth
US10520514B2 (en) * 2017-02-01 2019-12-31 Korea Institute Of Science And Technology Method for monitoring post-translational modification of protein
CN119804399A (zh) 2018-04-19 2025-04-11 曙光诊断学公司 靶标检测
AU2019353145B2 (en) 2018-10-04 2025-12-04 First Light Diagnostics, Inc. Microbial analysis without cell purification
WO2020172496A1 (en) * 2019-02-21 2020-08-27 Ding Qinxue Method of removing non-specific binding signals using microparticles
CN113125731B (zh) * 2019-12-31 2025-09-16 科美博阳诊断技术(上海)有限公司 一种竞争性均相化学发光测定试剂盒及其应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0101228B1 (de) * 1982-08-06 1986-10-08 International Institute Of Cellular And Molecular Pathology (Icp) Bestimmung von Antigenen durch Teilchenagglutination
US4590169A (en) * 1983-11-18 1986-05-20 Beckman Instruments, Inc. Direct particle agglutination immunoassays avoiding false negatives at high antigen concentrations
US4595661A (en) * 1983-11-18 1986-06-17 Beckman Instruments, Inc. Immunoassays and kits for use therein which include low affinity antibodies for reducing the hook effect
US4665020A (en) * 1984-05-30 1987-05-12 United States Department Of Energy Flow cytometer measurement of binding assays
JPS60256057A (ja) * 1984-06-01 1985-12-17 Dai Ichi Pure Chem Co Ltd 免疫学的測定法
JPS61290362A (ja) * 1985-06-18 1986-12-20 Showa Denko Kk 微粒子測定法
US5047321A (en) * 1988-06-15 1991-09-10 Becton Dickinson & Co. Method for analysis of cellular components of a fluid

Also Published As

Publication number Publication date
NO164622C (no) 1990-10-24
US5585241A (en) 1996-12-17
JPH03504276A (ja) 1991-09-19
AU3565889A (en) 1989-11-29
NO882067L (no) 1989-11-13
NO164622B (no) 1990-07-16
EP0413741B1 (de) 1995-08-30
EP0413741A1 (de) 1991-02-27
WO1989011101A1 (en) 1989-11-16
JP2742953B2 (ja) 1998-04-22
DE68924064D1 (de) 1995-10-05
DE68924064T2 (de) 1996-02-08
NO882067D0 (no) 1988-05-11
CA1335238C (en) 1995-04-18

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