ATE128462T1 - Cyclische hydroxamsaeuren und ihre verwendung. - Google Patents

Cyclische hydroxamsaeuren und ihre verwendung.

Info

Publication number
ATE128462T1
ATE128462T1 AT91908579T AT91908579T ATE128462T1 AT E128462 T1 ATE128462 T1 AT E128462T1 AT 91908579 T AT91908579 T AT 91908579T AT 91908579 T AT91908579 T AT 91908579T AT E128462 T1 ATE128462 T1 AT E128462T1
Authority
AT
Austria
Prior art keywords
pct
hydrogen
halogen
lower alkyl
date oct
Prior art date
Application number
AT91908579T
Other languages
English (en)
Inventor
Reijo Baeckstroem
Erkki Honkanen
Atso Raasmaja
Inge-Britt Linden
Original Assignee
Orion Yhtymae Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orion Yhtymae Oy filed Critical Orion Yhtymae Oy
Application granted granted Critical
Publication of ATE128462T1 publication Critical patent/ATE128462T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/46—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with hetero atoms directly attached to the ring nitrogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrrole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Earth Drilling (AREA)
AT91908579T 1990-04-26 1991-04-26 Cyclische hydroxamsaeuren und ihre verwendung. ATE128462T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB909009395A GB9009395D0 (en) 1990-04-26 1990-04-26 Cyclic hydroxamic acids and their use

Publications (1)

Publication Number Publication Date
ATE128462T1 true ATE128462T1 (de) 1995-10-15

Family

ID=10675035

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91908579T ATE128462T1 (de) 1990-04-26 1991-04-26 Cyclische hydroxamsaeuren und ihre verwendung.

Country Status (13)

Country Link
US (1) US5356923A (de)
EP (1) EP0526535B1 (de)
JP (1) JP3227155B2 (de)
AT (1) ATE128462T1 (de)
AU (1) AU7777491A (de)
DE (1) DE69113455T2 (de)
DK (1) DK0526535T3 (de)
ES (1) ES2078519T3 (de)
FI (1) FI100052B (de)
GB (1) GB9009395D0 (de)
GR (1) GR3017821T3 (de)
WO (1) WO1991016303A1 (de)
ZA (1) ZA912886B (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5234933A (en) * 1991-10-31 1993-08-10 Board Of Governors Of Wayne State University And Vanderbilt University Cyclic hydroxamic acids
ES2102036T3 (es) * 1992-06-15 1997-07-16 Celltech Therapeutics Ltd Derivados con grupo fenilo trisustituido utilizados como inhibidores selectivos de la fosfodiesterasa iv.
JP3775685B2 (ja) 1993-07-28 2006-05-17 ローン−プーラン・ロレ・リミテツド Ｐｄｅ▲ｉｖ▼およびｔｎｆ抑制剤としての化合物
US5665754A (en) * 1993-09-20 1997-09-09 Glaxo Wellcome Inc. Substituted pyrrolidines
US5502072A (en) * 1993-11-26 1996-03-26 Pfizer Inc. Substituted oxindoles
CA2143143A1 (en) * 1994-03-08 1995-09-09 Toshihiko Tanaka 3-phenylpyrrolidine derivatives
IL161317A0 (en) 2001-10-16 2004-09-27 Memory Pharm Corp 4-(4-alkoxy-3-hydroxyphenyl)-2-pyrrolidone derivatives as pde-4 inhibitors for the treatment of neurological syndromes
SG169900A1 (en) 2003-04-16 2011-04-29 Memory Pharm Corp 4 - (3,4 - disubstituted phenyl) - pyrrolidin-2-one compounds as phosphodiesterase 4 inhibitors
EP1802615A1 (de) 2004-10-20 2007-07-04 Memory Pharmaceuticals Corporation Phosphodiesterase-4-inhibitoren
CN102491929B (zh) * 2011-12-08 2014-04-30 贵州省中国科学院天然产物化学重点实验室 1-羟基-2-吡咯烷酮类化合物及其制备方法和应用
CN110407681B (zh) * 2019-08-12 2023-05-02 海南大学 一种脱氢姜酮衍生物、其制备方法及应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4193926A (en) * 1974-03-20 1980-03-18 Schering Aktiengesellschaft 4-(Polyalkoxy phenyl)-2-pyrrolidones
DE2413935A1 (de) * 1974-03-20 1975-10-16 Schering Ag 4-(polyalkoxy-phenyl)-2-pyrrolidone
LU85404A1 (fr) * 1984-06-06 1986-01-24 Continental Pharma Derives d'acides hydroxamiques cycliques,leur preparation et utilisation ainsi que les compositions contenant ces derives
DE3686733T2 (de) * 1985-03-16 1993-02-11 Wellcome Found Aryl-derivate.
IE59397B1 (en) * 1985-03-16 1994-02-23 Wellcome Found New aryl derivatives
GB8531839D0 (en) * 1985-12-30 1986-02-05 Wellcome Found Aryl derivatives

Also Published As

Publication number Publication date
FI924839A7 (fi) 1992-10-23
EP0526535B1 (de) 1995-09-27
DK0526535T3 (da) 1995-11-27
GB9009395D0 (en) 1990-06-20
US5356923A (en) 1994-10-18
FI100052B (fi) 1997-09-15
JPH05506236A (ja) 1993-09-16
GR3017821T3 (en) 1996-01-31
FI924839A0 (fi) 1992-10-23
WO1991016303A1 (en) 1991-10-31
EP0526535A1 (de) 1993-02-10
DE69113455T2 (de) 1996-03-21
AU7777491A (en) 1991-11-11
JP3227155B2 (ja) 2001-11-12
ZA912886B (en) 1992-01-29
DE69113455D1 (de) 1995-11-02
ES2078519T3 (es) 1995-12-16

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee