ATE129154T1 - Verwendung eines reinen opiatantagonisten, z.b. nalmefen, naltrexon, naloxon oder diprenorphin, zur behandlung von mastzell-erkrankungen. - Google Patents

Verwendung eines reinen opiatantagonisten, z.b. nalmefen, naltrexon, naloxon oder diprenorphin, zur behandlung von mastzell-erkrankungen.

Info

Publication number: ATE129154T1
Authority: AT; Austria
Prior art keywords: diprenorphine; nalmefene; naltrexone; mast cell; naloxone
Prior art date: 1990-08-10

Application number

AT91307365T

Other languages

English (en)

Inventor

Phillip Frost

Original Assignee

Baker Norton Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-08-10

Filing date

1991-08-09

Publication date

1995-11-15

1991-08-09 Application filed by Baker Norton Pharma filed Critical Baker Norton Pharma

1995-11-15 Application granted granted Critical

1995-11-15 Publication of ATE129154T1 publication Critical patent/ATE129154T1/de

Links

OIJXLIIMXHRJJH-KNLIIKEYSA-N Diprenorphine Chemical compound C([C@]12[C@H]3OC=4C(O)=CC=C(C2=4)C[C@@H]2[C@]11CC[C@]3([C@H](C1)C(C)(C)O)OC)CN2CC1CC1 OIJXLIIMXHRJJH-KNLIIKEYSA-N 0.000 title abstract 2
208000035268 Mast Cell Activation disease Diseases 0.000 title abstract 2
WJBLNOPPDWQMCH-MBPVOVBZSA-N Nalmefene Chemical compound N1([C@@H]2CC3=CC=C(C=4O[C@@H]5[C@](C3=4)([C@]2(CCC5=C)O)CC1)O)CC1CC1 WJBLNOPPDWQMCH-MBPVOVBZSA-N 0.000 title abstract 2
229950002494 diprenorphine Drugs 0.000 title abstract 2
229960005297 nalmefene Drugs 0.000 title abstract 2
229960003086 naltrexone Drugs 0.000 title abstract 2
DQCKKXVULJGBQN-XFWGSAIBSA-N naltrexone Chemical compound N1([C@@H]2CC3=CC=C(C=4O[C@@H]5[C@](C3=4)([C@]2(CCC5=O)O)CC1)O)CC1CC1 DQCKKXVULJGBQN-XFWGSAIBSA-N 0.000 title abstract 2
UZHSEJADLWPNLE-GRGSLBFTSA-N naloxone Chemical compound O=C([C@@H]1O2)CC[C@@]3(O)[C@H]4CC5=CC=C(O)C2=C5[C@@]13CCN4CC=C UZHSEJADLWPNLE-GRGSLBFTSA-N 0.000 title 1
229960004127 naloxone Drugs 0.000 title 1
239000003401 opiate antagonist Substances 0.000 title 1
239000005557 antagonist Substances 0.000 abstract 1
239000003887 narcotic antagonist Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Public Health (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Emergency Medicine (AREA)
Epidemiology (AREA)
Immunology (AREA)
Pulmonology (AREA)
Dermatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)

AT91307365T 1990-08-10 1991-08-09 Verwendung eines reinen opiatantagonisten, z.b. nalmefen, naltrexon, naloxon oder diprenorphin, zur behandlung von mastzell-erkrankungen. ATE129154T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US07/565,428 US5057322A (en)	1990-08-10	1990-08-10	Method of treating mast cell disease

Publications (1)

Publication Number	Publication Date
ATE129154T1 true ATE129154T1 (de)	1995-11-15

Family

ID=24258552

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT91307365T ATE129154T1 (de)	1990-08-10	1991-08-09	Verwendung eines reinen opiatantagonisten, z.b. nalmefen, naltrexon, naloxon oder diprenorphin, zur behandlung von mastzell-erkrankungen.

Country Status (10)

Country	Link
US (1)	US5057322A (de)
EP (1)	EP0471525B1 (de)
JP (1)	JP2559304B2 (de)
AT (1)	ATE129154T1 (de)
AU (1)	AU8166291A (de)
CA (1)	CA2048894C (de)
DE (1)	DE69113921T2 (de)
DK (1)	DK0471525T3 (de)
ES (1)	ES2078450T3 (de)
GR (1)	GR3018335T3 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5648355A (en) *	1994-02-09	1997-07-15	Kos Pharmaceutical, Inc.	Method of treatment of endogenous, painful gastrointestinal conditions of non-inflammatory, non-ulcerative origin
WO1997018781A1 (en) *	1995-11-20	1997-05-29	University Of Miami	Method of treating nicotine dependence
EP1423116A1 (de) *	2001-08-14	2004-06-02	Biotie Therapies Corp.	Verfahren zur behandlung von alkoholismus oder alkoholmissbrauch
US7501433B2 (en)	2002-05-17	2009-03-10	Jenken Biosciences, Inc.	Opioid and opioid-like compounds and uses thereof
US8017622B2 (en) *	2003-05-16	2011-09-13	Jenken Biosciences, Inc.	Opioid and opioid-like compounds and uses thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4454142A (en) *	1983-05-26	1984-06-12	Key Pharmaceuticals, Inc.	Hyperkinetic child treatment agent
US4626539A (en) *	1984-08-10	1986-12-02	E. I. Dupont De Nemours And Company	Trandermal delivery of opioids
HU196376B (en) *	1985-05-23	1988-11-28	Sandoz Ag	Process for preparing morphinane derivatives and pharmaceutical compositions containing such compounds
JPS63501717A (ja) *	1985-10-29	1988-07-14	ベーカー・カミンス・デルマトロジカルス・インコーポレーテッド	抗原誘発性アレルギ−反応を阻止するための方法および組成物
US4673679A (en) *	1986-05-14	1987-06-16	E. I. Du Pont De Nemours And Company	Use of prodrugs of 3-hydroxymorphinans to prevent bitter taste upon buccal, nasal or sublingual administration
US4877791A (en) *	1988-11-01	1989-10-31	Baker Cummins Pharmaceuticals, Inc.	Method of treatment for interestitial cystitis
US4923875A (en) *	1989-07-10	1990-05-08	Baker Cummins Pharmaceuticals, Inc.	Method for treatment of mast cell-mediated dermatologic disorders

1990
- 1990-08-10 US US07/565,428 patent/US5057322A/en not_active Expired - Fee Related
1991
- 1991-08-06 AU AU81662/91A patent/AU8166291A/en not_active Abandoned
- 1991-08-08 JP JP3225233A patent/JP2559304B2/ja not_active Expired - Lifetime
- 1991-08-09 DK DK91307365.6T patent/DK0471525T3/da active
- 1991-08-09 CA CA002048894A patent/CA2048894C/en not_active Expired - Fee Related
- 1991-08-09 EP EP91307365A patent/EP0471525B1/de not_active Expired - Lifetime
- 1991-08-09 AT AT91307365T patent/ATE129154T1/de not_active IP Right Cessation
- 1991-08-09 ES ES91307365T patent/ES2078450T3/es not_active Expired - Lifetime
- 1991-08-09 DE DE69113921T patent/DE69113921T2/de not_active Expired - Fee Related
1995
- 1995-12-08 GR GR950403446T patent/GR3018335T3/el unknown

Also Published As

Publication number	Publication date
AU8166291A (en)	1992-02-13
JPH04230629A (ja)	1992-08-19
EP0471525B1 (de)	1995-10-18
EP0471525A1 (de)	1992-02-19
CA2048894C (en)	1995-10-17
US5057322A (en)	1991-10-15
DE69113921D1 (de)	1995-11-23
DE69113921T2 (de)	1996-05-15
CA2048894A1 (en)	1992-02-11
DK0471525T3 (da)	1996-02-19
ES2078450T3 (es)	1995-12-16
GR3018335T3 (en)	1996-03-31
JP2559304B2 (ja)	1996-12-04

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Legal Events

Date	Code	Title	Description
1996-04-15	UEP	Publication of translation of european patent specification
1999-05-15	REN	Ceased due to non-payment of the annual fee