EE03265B1 - Valu vaigistavad opioidpeptiidid ja nende kasutamine - Google Patents

Valu vaigistavad opioidpeptiidid ja nende kasutamine

Info

Publication number
EE03265B1
EE03265B1 EE9600071A EE9600071A EE03265B1 EE 03265 B1 EE03265 B1 EE 03265B1 EE 9600071 A EE9600071 A EE 9600071A EE 9600071 A EE9600071 A EE 9600071A EE 03265 B1 EE03265 B1 EE 03265B1
Authority
EE
Estonia
Prior art keywords
peptides
pain
opioid
relieved
compositions
Prior art date
Application number
EE9600071A
Other languages
English (en)
Inventor
Brown William
Dimaio John
Schiller Peter
Martel Ren�
Original Assignee
Astra Aktiebolag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB9403263A external-priority patent/GB9403263D0/en
Priority claimed from SE9401519A external-priority patent/SE9401519D0/xx
Application filed by Astra Aktiebolag filed Critical Astra Aktiebolag
Publication of EE03265B1 publication Critical patent/EE03265B1/et

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1016—Tetrapeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Rheumatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
EE9600071A 1994-02-21 1995-02-15 Valu vaigistavad opioidpeptiidid ja nende kasutamine EE03265B1 (et)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB9403263A GB9403263D0 (en) 1994-02-21 1994-02-21 Novel opiod peptides
GB9408179A GB9408179D0 (en) 1994-02-21 1994-04-25 Novel opioid peptides for the treatment of pain and use thereof
SE9401519A SE9401519D0 (sv) 1994-05-03 1994-05-03 Novel opioid peptides for the tratment of pain and use thereof
PCT/SE1995/000158 WO1995022557A1 (en) 1994-02-21 1995-02-15 Novel opioid peptides for the treatment of pain and use thereof

Publications (1)

Publication Number Publication Date
EE03265B1 true EE03265B1 (et) 2000-04-17

Family

ID=27267061

Family Applications (1)

Application Number Title Priority Date Filing Date
EE9600071A EE03265B1 (et) 1994-02-21 1995-02-15 Valu vaigistavad opioidpeptiidid ja nende kasutamine

Country Status (20)

Country Link
EP (1) EP0746567B1 (et)
JP (1) JPH09509168A (et)
AT (1) ATE217011T1 (et)
BR (1) BR9506847A (et)
CA (1) CA2181367A1 (et)
CZ (1) CZ288523B6 (et)
DE (1) DE69526577T2 (et)
EE (1) EE03265B1 (et)
ES (1) ES2176322T3 (et)
FI (1) FI963252L (et)
HR (1) HRP950413A2 (et)
HU (1) HUT74731A (et)
IS (1) IS4261A (et)
MX (1) MX9603489A (et)
NO (1) NO963464L (et)
NZ (1) NZ281742A (et)
PL (1) PL181092B1 (et)
SK (1) SK93596A3 (et)
TW (1) TW408131B (et)
WO (1) WO1995022557A1 (et)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9503924D0 (sv) 1995-08-18 1995-11-07 Astra Ab Novel opioid peptides
DE69623635T2 (de) * 1995-06-07 2003-05-08 Torrey Pines Institute For Molecular Studies, San Diego Mu-opioidligande: agonisten und antagonisten
GB9516994D0 (en) * 1995-08-18 1995-10-18 Iaf Biochem Int Solution synthesis of peripheral acting analgestic opioid tetrapeptides
MX9709494A (es) * 1996-12-04 1998-07-31 Pfizer Compuestos peptidicos ciclicos, procedimiento para su produccion, composiciones que los contienen y uso de los mismos.
US5885958A (en) 1997-03-25 1999-03-23 Administrators Of The Tulane Educational Fund Mu-opiate receptor peptides
US6548637B1 (en) 1998-06-18 2003-04-15 Sepracor, Inc. Ligands for opioid receptors
SE9900961D0 (sv) 1999-03-16 1999-03-16 Astra Ab Novel compounds
US7115664B2 (en) 2000-03-16 2006-10-03 Sepracor Inc. Peptidomimetic ligands for cellular receptors and ion channels
EP1303186B1 (en) * 2000-07-18 2011-01-26 Cornell Research Foundation, Inc. Medicinal uses of mu-opioid receptor agonists
SI2656854T1 (sl) 2003-02-04 2015-09-30 Cornell Research Foundation, Inc. Uporabe aromatsko-kationskega peptida
JP4879020B2 (ja) 2003-05-01 2012-02-15 コーネル リサーチ ファウンデイション インコーポレイテッド 細胞に分子を送達する方法及び担体複合体
CA2851972C (en) 2004-01-23 2015-06-23 Cornell Research Foundation, Inc. Methods for reducing oxidative damage
JP4173909B1 (ja) 2005-04-28 2008-10-29 ファイザー・リミテッド アミノ酸誘導体
CA2947335A1 (en) 2005-09-16 2007-03-29 Cornell Research Foundation, Inc. Methods for reducing cd36 expression
EP1782819A1 (en) 2005-11-03 2007-05-09 Cognis IP Management GmbH Oligopeptides and their use
US7842662B2 (en) 2006-11-10 2010-11-30 Cara Therapeutics, Inc. Synthetic peptide amide dimers
US8236766B2 (en) 2006-11-10 2012-08-07 Cara Therapeutics, Inc. Uses of synthetic peptide amides
MX2009005000A (es) 2006-11-10 2009-10-12 Cara Therapeutics Inc Amidas de peptidos sinteticos.
US7713937B2 (en) 2006-11-10 2010-05-11 Cara Therapeutics, Inc. Synthetic peptide amides and dimeric forms thereof
US8906859B2 (en) 2006-11-10 2014-12-09 Cera Therapeutics, Inc. Uses of kappa opioid synthetic peptide amides
CN102127152B (zh) * 2007-06-11 2012-07-04 北京大学 一种抗阿片肽的拮抗肽与该拮抗肽的应用
CN102127151B (zh) * 2007-06-11 2012-07-04 北京大学 抗阿片肽的拮抗肽与该拮抗肽的应用
CN101805396B (zh) * 2007-06-28 2011-09-14 北京大学 抗阿片肽的拮抗肽与该拮抗肽的应用
CN101817877B (zh) * 2007-06-28 2011-09-14 北京大学 一种抗阿片肽的活性片段
EP3103467A1 (en) 2008-02-07 2016-12-14 Cornell University Methods for preventing or treating insulin resistance
DK2262520T3 (en) 2008-02-26 2017-08-07 Univ Cornell COMPOSITIONS FOR PREVENTION AND TREATMENT OF Kidney Injury
CN112469729A (zh) * 2018-05-31 2021-03-09 悉尼大学 镇痛剂及其使用方法
JP7437578B2 (ja) * 2019-03-20 2024-02-26 国立大学法人東北大学 新規オピオイドペプチド、その糖鎖付加体及びそれらを含む医薬組成物
CN113968902B (zh) * 2020-07-25 2023-05-26 兰州大学 亮氨酸-脑啡肽类似物及其制备方法和应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8005121A (nl) * 1979-09-20 1981-03-24 Erba Farmitalia Biologisch actieve peptiden.
PT644772E (pt) * 1992-11-12 2003-08-29 Conseils De Rec Appl Scient S Peptidos opioides
SE9300012D0 (sv) * 1993-01-05 1993-01-05 Astra Ab New peptides

Also Published As

Publication number Publication date
ATE217011T1 (de) 2002-05-15
EP0746567B1 (en) 2002-05-02
AU690648B2 (en) 1998-04-30
NO963464L (no) 1996-08-20
FI963252A7 (fi) 1996-08-20
CZ288523B6 (cs) 2001-07-11
HUT74731A (en) 1997-02-28
CZ239196A3 (en) 1996-12-11
PL315947A1 (en) 1996-12-09
DE69526577D1 (de) 2002-06-06
EP0746567A1 (en) 1996-12-11
HU9602281D0 (en) 1996-10-28
JPH09509168A (ja) 1997-09-16
FI963252A0 (fi) 1996-08-20
DE69526577T2 (de) 2003-01-02
MX9603489A (es) 1997-03-29
IS4261A (is) 1995-08-22
NZ281742A (en) 1997-06-24
WO1995022557A1 (en) 1995-08-24
BR9506847A (pt) 1997-09-30
PL181092B1 (pl) 2001-05-31
FI963252L (fi) 1996-08-20
CA2181367A1 (en) 1995-08-24
SK93596A3 (en) 1997-05-07
TW408131B (en) 2000-10-11
HRP950413A2 (en) 1997-10-31
AU1865195A (en) 1995-09-04
ES2176322T3 (es) 2002-12-01

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Effective date: 20020215