ATE130030T1 - Neue coenzym unabhängige l-sorbosone dehydrogenase. - Google Patents

Neue coenzym unabhängige l-sorbosone dehydrogenase.

Info

Publication number: ATE130030T1
Authority: AT; Austria
Prior art keywords: pct; sorbosone; sec; date; sorbosone dehydrogenase
Prior art date: 1988-01-14

Application number

AT89901549T

Other languages

English (en)

Inventor

Akiko Fujiwara

Tatsuo Hoshino

Masako Dai Ohfuna Park Shinjoh

Totsuka-Ku

Original Assignee

Hoffmann La Roche

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-01-14

Filing date

1989-01-09

Publication date

1995-11-15

1989-01-09 Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche

1995-11-15 Application granted granted Critical

1995-11-15 Publication of ATE130030T1 publication Critical patent/ATE130030T1/de

Links

108010053002 L-sorbosone dehydrogenase Proteins 0.000 title abstract 2
239000005515 coenzyme Substances 0.000 title abstract 2
VBUYCZFBVCCYFD-NUNKFHFFSA-N 2-dehydro-L-idonic acid Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)C(=O)C(O)=O VBUYCZFBVCCYFD-NUNKFHFFSA-N 0.000 abstract 1
VBUYCZFBVCCYFD-UHFFFAOYSA-N D-arabino-2-Hexulosonic acid Natural products OCC(O)C(O)C(O)C(=O)C(O)=O VBUYCZFBVCCYFD-UHFFFAOYSA-N 0.000 abstract 1
108090000790 Enzymes Proteins 0.000 abstract 1
102000004190 Enzymes Human genes 0.000 abstract 1
241000589232 Gluconobacter oxydans Species 0.000 abstract 1
DCNMIDLYWOTSGK-KVQBGUIXSA-N L-xylo-hexos-2-ulose Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)C(=O)C=O DCNMIDLYWOTSGK-KVQBGUIXSA-N 0.000 abstract 1
230000005764 inhibitory process Effects 0.000 abstract 1
244000005700 microbiome Species 0.000 abstract 1
238000002415 sodium dodecyl sulfate polyacrylamide gel electrophoresis Methods 0.000 abstract 1
239000000126 substance Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
- C12P7/58—Aldonic, ketoaldonic or saccharic acids
- C12P7/60—2-Ketogulonic acid

Landscapes

Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
Bioinformatics & Cheminformatics (AREA)
Biotechnology (AREA)
General Engineering & Computer Science (AREA)
Microbiology (AREA)
Biomedical Technology (AREA)
Biochemistry (AREA)
General Health & Medical Sciences (AREA)
Molecular Biology (AREA)
Physics & Mathematics (AREA)
Medicinal Chemistry (AREA)
Biophysics (AREA)
Plant Pathology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Enzymes And Modification Thereof (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Peptides Or Proteins (AREA)

AT89901549T 1988-01-14 1989-01-09 Neue coenzym unabhängige l-sorbosone dehydrogenase. ATE130030T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP88100419		1988-01-14

Publications (1)

Publication Number	Publication Date
ATE130030T1 true ATE130030T1 (de)	1995-11-15

Family

ID=8198642

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT89901549T ATE130030T1 (de)	1988-01-14	1989-01-09	Neue coenzym unabhängige l-sorbosone dehydrogenase.

Country Status (7)

Country	Link
US (1)	US5352599A (de)
EP (1)	EP0373181B1 (de)
JP (1)	JP2799380B2 (de)
AT (1)	ATE130030T1 (de)
DE (1)	DE68924761T2 (de)
DK (1)	DK454689D0 (de)
WO (1)	WO1989006688A2 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DK0381027T3 (da) *	1989-02-02	1995-04-10	Hoffmann La Roche	Shuttlevektorer, som kan anvendes i mikroorganismer tilhørende Escherichia coli, Gluconobacter og Acetobacter
US5399496A (en) *	1989-02-02	1995-03-21	Hoffman-Laroche Inc.	DNA shuttle vectors for E. coli, Gluconobacter, and Acetobacter
IL104419A0 (en) *	1992-01-24	1993-05-13	Fmc Corp	Insecticidally effective peptides
US5437989A (en) *	1992-12-30	1995-08-01	Hoffmann-La Roche Inc.	Alcohol/aldehyde dehydrogenase from Gluconobacter oxydans DSM 4025 FERM BP-3812
CA2157762A1 (en) *	1993-03-08	1994-09-15	Mineo Niwa	Novel l-sorbose dehydrogenase and novel l-sorbosone dehydrogenase obtained from gluconobacter oxydans t-100
EP0758679A4 (de) *	1994-02-25	1999-03-17	Fujisawa Pharmaceutical Co	Verfahren zur herstellung von 2-keto-l-gulonsäure
US5776742A (en) *	1996-02-19	1998-07-07	Roche Vitamins Inc.	Aldehyde dehydrogenase enzyme
ATE493496T1 (de)	1996-09-19	2011-01-15	Dsm Ip Assets Bv	Alkohol-aldehyd-deshydrogenasen
US6730503B1 (en) *	1996-09-19	2004-05-04	Roche Vitamins Inc.	Alcohol/aldehyde dehydrogenase
NO981220L (no) *	1997-04-04	1998-10-05	Hoffmann La Roche	Cytokrom c samt gen for dette
US6407203B1 (en)	1997-04-04	2002-06-18	Roche Vitamins, Inc.	Cytochrome c and polynucleotides encoding cytochrome c
CA2239802A1 (en)	1997-08-21	1999-02-21	F. Hoffmann-La Roche Ag	D-sorbitol dehydrogenase gene
EP1543114B1 (de)	2002-09-27	2008-08-13	DSM IP Assets B.V.	Aldehyddehyrdrogenase-gen
KR101311562B1 (ko)	2003-08-14	2013-09-26	디에스엠 아이피 어셋츠 비.브이.	미생물을 이용한 ｌ-아스코르브산의 생산
CN100395332C (zh) *	2003-11-28	2008-06-18	华北制药集团有限责任公司	一种l-山梨酮脱氢酶及其编码基因与应用
WO2006084735A1 (en) *	2005-02-11	2006-08-17	Dsm Ip Assets B.V.	Gene for coenzyme pqq synthesis protein b from gluconobacter oxydans
WO2007028610A2 (en) *	2005-09-09	2007-03-15	Dsm Ip Assets B.V.	Novel gene gms 08

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3907639A (en) *	1972-08-31	1975-09-23	Hoffmann La Roche	Method for producing 2-keto-L-gulonic acid
US5008193A (en) *	1984-06-14	1991-04-16	Genentech, Inc.	Ascorbic acid intermediates and process enzymes
DK269987A (da) *	1986-06-03	1987-12-04	Hoffmann La Roche	Enzym og fremgangsmaade til fremstilling deraf
DK270087A (da) *	1986-06-03	1987-12-04	Hoffmann La Roche	Enzym og fremgangsmaade til fremstilling deraf
US5082785A (en) *	1987-01-30	1992-01-21	Hoffmann-La Roche Inc.	Biosynthesis of 2 keto-l-gulonic acid
US5085993A (en) *	1987-12-24	1992-02-04	Hoffmann-La Roche Inc.	Coenzyme-independent l-sorbosone dehydrogenase from pseudomonas putida

1989
- 1989-01-09 AT AT89901549T patent/ATE130030T1/de not_active IP Right Cessation
- 1989-01-09 JP JP1501447A patent/JP2799380B2/ja not_active Expired - Fee Related
- 1989-01-09 US US07/415,208 patent/US5352599A/en not_active Expired - Fee Related
- 1989-01-09 DE DE68924761T patent/DE68924761T2/de not_active Expired - Fee Related
- 1989-01-09 EP EP89901549A patent/EP0373181B1/de not_active Expired - Lifetime
- 1989-01-09 WO PCT/EP1989/000010 patent/WO1989006688A2/en not_active Ceased
- 1989-09-14 DK DK454689A patent/DK454689D0/da not_active Application Discontinuation

Also Published As

Publication number	Publication date
DE68924761D1 (de)	1995-12-14
US5352599A (en)	1994-10-04
DK454689A (da)	1989-09-14
DE68924761T2 (de)	1996-04-04
JP2799380B2 (ja)	1998-09-17
WO1989006688A3 (en)	1989-09-21
EP0373181B1 (de)	1995-11-08
DK454689D0 (da)	1989-09-14
EP0373181A1 (de)	1990-06-20
JPH03500844A (ja)	1991-02-28
WO1989006688A2 (en)	1989-07-27

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Legal Events

Date	Code	Title	Description
1996-06-15	UEP	Publication of translation of european patent specification
2002-10-15	REN	Ceased due to non-payment of the annual fee