ATE130510T1 - Rifaximin enthaltendes arzneimittel zur behandlung von vaginalinfektionen. - Google Patents
Rifaximin enthaltendes arzneimittel zur behandlung von vaginalinfektionen.Info
- Publication number
- ATE130510T1 ATE130510T1 AT92113603T AT92113603T ATE130510T1 AT E130510 T1 ATE130510 T1 AT E130510T1 AT 92113603 T AT92113603 T AT 92113603T AT 92113603 T AT92113603 T AT 92113603T AT E130510 T1 ATE130510 T1 AT E130510T1
- Authority
- AT
- Austria
- Prior art keywords
- treatment
- vaginal
- vaginal infections
- containing rifaximin
- rifaximin
- Prior art date
Links
- NZCRJKRKKOLAOJ-XRCRFVBUSA-N rifaximin Chemical compound OC1=C(C(O)=C2C)C3=C4N=C5C=C(C)C=CN5C4=C1NC(=O)\C(C)=C/C=C/[C@H](C)[C@H](O)[C@@H](C)[C@@H](O)[C@@H](C)[C@H](OC(C)=O)[C@H](C)[C@@H](OC)\C=C\O[C@@]1(C)OC2=C3C1=O NZCRJKRKKOLAOJ-XRCRFVBUSA-N 0.000 title abstract 2
- 229960003040 rifaximin Drugs 0.000 title abstract 2
- 208000015181 infectious disease Diseases 0.000 title 1
- 208000004926 Bacterial Vaginosis Diseases 0.000 abstract 1
- 206010046914 Vaginal infection Diseases 0.000 abstract 1
- 208000037009 Vaginitis bacterial Diseases 0.000 abstract 1
- 239000002674 ointment Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000000699 topical effect Effects 0.000 abstract 1
- 239000000259 vaginal foam Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Reproductive Health (AREA)
- Organic Chemistry (AREA)
- Urology & Nephrology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Gynecology & Obstetrics (AREA)
- Communicable Diseases (AREA)
- Endocrinology (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITBO910476A IT1253711B (it) | 1991-12-17 | 1991-12-17 | Formulazioni farmaceutiche vaginali contenenti rifaximin e loro uso nel trattamento delle infezioni vaginali |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE130510T1 true ATE130510T1 (de) | 1995-12-15 |
Family
ID=11337881
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT92113603T ATE130510T1 (de) | 1991-12-17 | 1992-08-10 | Rifaximin enthaltendes arzneimittel zur behandlung von vaginalinfektionen. |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US5314904A (de) |
| EP (1) | EP0547294B1 (de) |
| JP (1) | JP2834951B2 (de) |
| KR (1) | KR0149519B1 (de) |
| AT (1) | ATE130510T1 (de) |
| CA (1) | CA2073601C (de) |
| DE (1) | DE69206245T2 (de) |
| DK (1) | DK0547294T3 (de) |
| ES (1) | ES2081531T3 (de) |
| GR (1) | GR3018205T3 (de) |
| IT (1) | IT1253711B (de) |
| MX (1) | MX9204132A (de) |
| TW (1) | TW217385B (de) |
Families Citing this family (83)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6861053B1 (en) | 1999-08-11 | 2005-03-01 | Cedars-Sinai Medical Center | Methods of diagnosing or treating irritable bowel syndrome and other disorders caused by small intestinal bacterial overgrowth |
| US7048906B2 (en) | 1995-05-17 | 2006-05-23 | Cedars-Sinai Medical Center | Methods of diagnosing and treating small intestinal bacterial overgrowth (SIBO) and SIBO-related conditions |
| US20030118645A1 (en) * | 1998-04-29 | 2003-06-26 | Pather S. Indiran | Pharmaceutical compositions for rectal and vaginal administration |
| US6974590B2 (en) * | 1998-03-27 | 2005-12-13 | Cima Labs Inc. | Sublingual buccal effervescent |
| US20030091629A1 (en) * | 1998-03-27 | 2003-05-15 | Cima Labs Inc. | Sublingual buccal effervescent |
| US6462030B1 (en) * | 1999-07-19 | 2002-10-08 | New York Blood Center, Inc. | Method for inactivating bacteria associated with bacterial vaginosis using cellulose acetate phthalate and/or hydroxypropyl methycellulose phthalate |
| US6251136B1 (en) * | 1999-12-08 | 2001-06-26 | Advanced Cardiovascular Systems, Inc. | Method of layering a three-coated stent using pharmacological and polymeric agents |
| PL202918B1 (pl) | 2000-03-07 | 2009-08-31 | Rush Presbyterian St Luke | Przeciwbakteryjna i antykoncepcyjna kompozycja oraz jej zastosowanie |
| US8512718B2 (en) | 2000-07-03 | 2013-08-20 | Foamix Ltd. | Pharmaceutical composition for topical application |
| US6537538B2 (en) | 2000-12-18 | 2003-03-25 | Rush-Presbyterian-St. Luke's Medical Center | Method for the prevention, inhibition, or treatment of vaginitis and/or bacterial vaginosis using polystyrene sulfonate |
| KR100392363B1 (ko) * | 2000-12-26 | 2003-07-22 | 한국전자통신연구원 | 형광체 및 그 제조방법 |
| WO2003004098A1 (en) * | 2001-07-06 | 2003-01-16 | Sucampo Ag | Composition for topical administration comprising an interleukin-2 inhibitor and an antimicrobial agent |
| IL152486A0 (en) | 2002-10-25 | 2003-05-29 | Meir Eini | Alcohol-free cosmetic and pharmaceutical foam carrier |
| US7820145B2 (en) | 2003-08-04 | 2010-10-26 | Foamix Ltd. | Oleaginous pharmaceutical and cosmetic foam |
| US9668972B2 (en) | 2002-10-25 | 2017-06-06 | Foamix Pharmaceuticals Ltd. | Nonsteroidal immunomodulating kit and composition and uses thereof |
| US7704518B2 (en) | 2003-08-04 | 2010-04-27 | Foamix, Ltd. | Foamable vehicle and pharmaceutical compositions thereof |
| US20080138296A1 (en) | 2002-10-25 | 2008-06-12 | Foamix Ltd. | Foam prepared from nanoemulsions and uses |
| US7700076B2 (en) * | 2002-10-25 | 2010-04-20 | Foamix, Ltd. | Penetrating pharmaceutical foam |
| ES2532906T5 (es) | 2002-10-25 | 2022-03-23 | Foamix Pharmaceuticals Ltd | Espuma cosmética y farmacéutica |
| US9265725B2 (en) | 2002-10-25 | 2016-02-23 | Foamix Pharmaceuticals Ltd. | Dicarboxylic acid foamable vehicle and pharmaceutical compositions thereof |
| US9211259B2 (en) | 2002-11-29 | 2015-12-15 | Foamix Pharmaceuticals Ltd. | Antibiotic kit and composition and uses thereof |
| US8119109B2 (en) | 2002-10-25 | 2012-02-21 | Foamix Ltd. | Foamable compositions, kits and methods for hyperhidrosis |
| US8486376B2 (en) | 2002-10-25 | 2013-07-16 | Foamix Ltd. | Moisturizing foam containing lanolin |
| US8119150B2 (en) | 2002-10-25 | 2012-02-21 | Foamix Ltd. | Non-flammable insecticide composition and uses thereof |
| US8900554B2 (en) | 2002-10-25 | 2014-12-02 | Foamix Pharmaceuticals Ltd. | Foamable composition and uses thereof |
| US10117812B2 (en) | 2002-10-25 | 2018-11-06 | Foamix Pharmaceuticals Ltd. | Foamable composition combining a polar solvent and a hydrophobic carrier |
| EP1560566B1 (de) | 2002-11-05 | 2012-04-11 | Fadim S.r.l. | Kontrollierte und kontinuierliche verabreichung von rifaximin |
| US7575739B2 (en) | 2003-04-28 | 2009-08-18 | Foamix Ltd. | Foamable iodine composition |
| ES2752773T3 (es) * | 2003-06-13 | 2020-04-06 | Idh Holding Aps | Tratamiento de los síntomas asociados a la vaginosis bacteriana |
| US8486374B2 (en) | 2003-08-04 | 2013-07-16 | Foamix Ltd. | Hydrophilic, non-aqueous pharmaceutical carriers and compositions and uses |
| US8795693B2 (en) | 2003-08-04 | 2014-08-05 | Foamix Ltd. | Compositions with modulating agents |
| US20060140990A1 (en) * | 2003-09-19 | 2006-06-29 | Drugtech Corporation | Composition for topical treatment of mixed vaginal infections |
| AU2004274000B2 (en) * | 2003-09-19 | 2009-07-30 | Drugtech Corporation | Pharmaceutical delivery system |
| CN102078310B (zh) * | 2003-12-31 | 2013-01-23 | 奇马实验室公司 | 大体线性的泡腾口服芬太尼剂型和施用方法 |
| US7862833B2 (en) * | 2003-12-31 | 2011-01-04 | Cima Labs, Inc. | Effervescent oral opiate dosage forms and methods of administering opiates |
| WO2005065317A2 (en) * | 2003-12-31 | 2005-07-21 | Cima Labs Inc. | Effervescent oral fentanyl dosage form |
| WO2005085287A1 (en) * | 2004-03-03 | 2005-09-15 | En-N-Tech, Inc. | Treatments for contaminant reduction in lactoferrin preparations and lactoferrin-containing compositions |
| US8003118B2 (en) * | 2005-03-02 | 2011-08-23 | Kodsi Robert E | Use of rifaximin for the prevention of aspiration pneumonia and/or sepsis |
| US20060210492A1 (en) * | 2005-03-02 | 2006-09-21 | Kodsi Robert E | Use of rifaximin for treatment and prevention of periodontal conditions |
| US20060210483A1 (en) * | 2005-03-02 | 2006-09-21 | Kodsi Robert E | Non-systemic antibiotic formulations and related method of use and treatment of upper respiratory infections |
| PT1698630E (pt) | 2005-03-03 | 2014-09-15 | Alfa Wassermann Spa | Novas formas polimorfas de rifaximina, processos para a sua produção e a sua utilização nas preparações medicinais |
| ITBO20050123A1 (it) | 2005-03-07 | 2005-06-06 | Alfa Wassermann Spa | Formulazioni farmaceutiche gastroresistenti contenenti rifaximina |
| WO2007039825A2 (en) * | 2005-05-09 | 2007-04-12 | Foamix Ltd. | Saccharide foamable compositions |
| MX2007013631A (es) * | 2005-05-09 | 2008-01-24 | Drugtech Corp | Composiciones farmaceuticas de liberacion modificada. |
| EA200870153A1 (ru) * | 2006-01-05 | 2008-12-30 | Драгтек Корпорейшн | Композиция и способ ее использования |
| KR20080083190A (ko) * | 2006-01-05 | 2008-09-16 | 드러그테크 코포레이션 | 외음질 표면에 생체접착을 위한 약물 전달 시스템 |
| ITMI20061692A1 (it) | 2006-09-05 | 2008-03-06 | Alfa Wassermann Spa | Uso di polioli per ottenere forme polimorfe stabili di rifaximina |
| US20080260655A1 (en) | 2006-11-14 | 2008-10-23 | Dov Tamarkin | Substantially non-aqueous foamable petrolatum based pharmaceutical and cosmetic compositions and their uses |
| US20080161337A1 (en) * | 2007-01-03 | 2008-07-03 | Leonard Weinstock | Use of Rifaximin for the Treatment of Chronic Prostatitis |
| US20080159987A1 (en) * | 2007-01-03 | 2008-07-03 | Leonard Weinstock | Use of Rifaximin for the Treatment of Restless Legs Syndrome |
| WO2008106646A2 (en) * | 2007-03-01 | 2008-09-04 | Introgen Therapeutics, Inc | Methods and formulations for topical gene therapy |
| PL2011486T5 (pl) * | 2007-07-06 | 2016-09-30 | Lupin Ltd | Farmaceutyczne kompozycje rifaksyminy |
| WO2009008005A1 (en) * | 2007-07-06 | 2009-01-15 | Lupin Limited | Pharmaceutical compositions of rifaximin |
| AU2016203925B2 (en) * | 2007-07-06 | 2016-10-20 | Lupin Limited | Pharmaceutical compositions of rifaximin |
| US8636982B2 (en) | 2007-08-07 | 2014-01-28 | Foamix Ltd. | Wax foamable vehicle and pharmaceutical compositions thereof |
| US9439857B2 (en) | 2007-11-30 | 2016-09-13 | Foamix Pharmaceuticals Ltd. | Foam containing benzoyl peroxide |
| WO2009072007A2 (en) | 2007-12-07 | 2009-06-11 | Foamix Ltd. | Carriers, formulations, methods for formulating unstable active agents for external application and uses thereof |
| US8518376B2 (en) | 2007-12-07 | 2013-08-27 | Foamix Ltd. | Oil-based foamable carriers and formulations |
| EP2242476A2 (de) | 2008-01-14 | 2010-10-27 | Foamix Ltd. | Aufschäumbare pharmazeutische poloxamer-zusammensetzungen mit wirkstoffen und/oder therapeutischen zellen und verwendungen |
| KR20110071096A (ko) | 2008-09-26 | 2011-06-28 | 아스카 세이야쿠 가부시키가이샤 | 기능성 소화관 장해의 예방 및/또는 치료제 |
| WO2010125470A2 (en) | 2009-04-28 | 2010-11-04 | Foamix Ltd. | Foamable vehicle and pharmaceutical compositions comprising aprotic polar solvents and uses thereof |
| CA2769677A1 (en) | 2009-07-29 | 2011-02-03 | Foamix Ltd. | Non surface active agent non polymeric agent hydro-alcoholic foamable compositions, breakable foams and their uses |
| WO2011013009A2 (en) | 2009-07-29 | 2011-02-03 | Foamix Ltd. | Non surfactant hydro-alcoholic foamable compositions, breakable foams and their uses |
| WO2011064631A1 (en) | 2009-10-02 | 2011-06-03 | Foamix Ltd. | Surfactant-free, water-free, foamable compositions and breakable foams and their uses |
| US9849142B2 (en) | 2009-10-02 | 2017-12-26 | Foamix Pharmaceuticals Ltd. | Methods for accelerated return of skin integrity and for the treatment of impetigo |
| GEP201706693B (en) * | 2009-10-27 | 2017-07-10 | Lupin Ltd | Solid dispersion of rifaximin |
| CA2781580A1 (en) | 2009-11-23 | 2011-05-26 | Cipla Limited | Topical foam composition |
| CN102724961A (zh) | 2009-11-23 | 2012-10-10 | 希普拉有限公司 | 局部泡沫组合物 |
| US7888062B1 (en) | 2010-02-01 | 2011-02-15 | Microbios, Inc. | Process and composition for the manufacture of a microbial-based product |
| US8445226B2 (en) | 2010-02-01 | 2013-05-21 | Microbios, Inc. | Process and composition for the manufacture of a microbial-based product |
| IT1398550B1 (it) | 2010-03-05 | 2013-03-01 | Alfa Wassermann Spa | Formulazioni comprendenti rifaximina utili per ottenere un effetto prolungato nel tempo |
| WO2012076832A1 (en) | 2010-12-09 | 2012-06-14 | Cipla Limited | Suppositories comprising rifaximin |
| ITBO20110461A1 (it) * | 2011-07-29 | 2013-01-30 | Alfa Wassermann Spa | Composizioni farmaceutiche comprendenti rifaximina, processi per la loro preparazione e loro uso nel trattamento di infezioni vaginali. |
| CN102512358B (zh) * | 2011-12-16 | 2013-04-10 | 南京农业大学 | 家畜用利福昔明阴道栓剂及其制备方法 |
| CA2897758A1 (en) | 2013-03-15 | 2014-09-18 | Alfa Wassermann S.P.A. | Rifaximin for use in the treating of vaginal infections |
| EP2971062A2 (de) | 2013-03-15 | 2016-01-20 | ALFA WASSERMANN S.p.A. | Verfahren zur diagnose von vaginalinfektionen |
| DK3546464T3 (da) | 2014-05-12 | 2020-07-27 | Alfasigma Spa | Fremstilling og anvendelse af den krystallinske form tau af rifaximin solvateret med degme |
| KR20170052626A (ko) | 2014-09-05 | 2017-05-12 | 심바이오믹스 세러퓨틱스 엘엘씨 | 세균질증 치료에 사용하기 위한 세크니다졸 |
| US10561680B2 (en) * | 2015-02-26 | 2020-02-18 | Fundació Institut D'investigació En Ciències De La Salut Germans Trias I Pujol | Topical composition for the treatment of mucosal lesions |
| US10398641B2 (en) | 2016-09-08 | 2019-09-03 | Foamix Pharmaceuticals Ltd. | Compositions and methods for treating rosacea and acne |
| US20190008784A1 (en) * | 2017-07-07 | 2019-01-10 | Symbiomix Therapeutics, Llc | Novel secnidazole soft gelatin capsule formulations and uses thereof |
| WO2019073321A1 (en) * | 2017-10-10 | 2019-04-18 | Zenvision Pharma Llp | EFFERVESCENT COMPOSITIONS COMPRISING RIFAXIMINE |
| US20230398102A1 (en) * | 2020-10-29 | 2023-12-14 | Bausch Health Ireland Limited | Rifaximin liquid formulations for use inthe treatment of sickle cell disease |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI812936A7 (fi) * | 1980-09-25 | 1982-03-26 | Ciba Geigy Ag | Uusia 2-aminoimidatsoleja, menetelmä niiden valmistamiseksi, näitä yhdisteitä sisältäviä farmaseuttisia valvalmisteita ja niiden käyttö. |
| ZA816635B (en) * | 1980-09-25 | 1982-09-29 | Ciba Geigy | Novel 2-aminoimidazoles |
| IT1190445B (it) * | 1985-11-08 | 1988-02-16 | Fatro Spa | Composizioni veterinarie a base di agenti antimicrobici e loro impiego |
| DE3815221C2 (de) * | 1988-05-04 | 1995-06-29 | Gradinger F Hermes Pharma | Verwendung einer Retinol- und/oder Retinsäureester enthaltenden pharmazeutischen Zubereitung zur Inhalation zur Einwirkung auf die Schleimhäute des Tracheo-Bronchialtraktes einschließlich der Lungenalveolen |
| DE69011557T2 (de) * | 1989-03-31 | 1995-03-23 | Lepetit Spa | Verwendung von Purpuromycin zur Behandlung von Vaginalinfektionen. |
| GB8908250D0 (en) * | 1989-04-12 | 1989-05-24 | Fisons Plc | Formulations |
| GB9001019D0 (en) * | 1990-01-17 | 1990-03-14 | Euro Celtique Sa | Pharmaceutical aerosol |
-
1991
- 1991-12-17 IT ITBO910476A patent/IT1253711B/it active IP Right Grant
-
1992
- 1992-06-16 US US07/899,421 patent/US5314904A/en not_active Expired - Lifetime
- 1992-07-08 TW TW081105403A patent/TW217385B/zh not_active IP Right Cessation
- 1992-07-10 CA CA002073601A patent/CA2073601C/en not_active Expired - Lifetime
- 1992-07-14 KR KR1019920012471A patent/KR0149519B1/ko not_active Expired - Lifetime
- 1992-07-15 MX MX9204132A patent/MX9204132A/es unknown
- 1992-08-10 AT AT92113603T patent/ATE130510T1/de active
- 1992-08-10 ES ES92113603T patent/ES2081531T3/es not_active Expired - Lifetime
- 1992-08-10 DE DE69206245T patent/DE69206245T2/de not_active Expired - Lifetime
- 1992-08-10 DK DK92113603.2T patent/DK0547294T3/da active
- 1992-08-10 EP EP92113603A patent/EP0547294B1/de not_active Expired - Lifetime
- 1992-10-05 JP JP4266034A patent/JP2834951B2/ja not_active Expired - Lifetime
-
1994
- 1994-01-13 US US08/181,259 patent/US6140355A/en not_active Expired - Lifetime
-
1995
- 1995-11-23 GR GR950403212T patent/GR3018205T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US6140355A (en) | 2000-10-31 |
| JP2834951B2 (ja) | 1998-12-14 |
| IT1253711B (it) | 1995-08-23 |
| KR930012015A (ko) | 1993-07-20 |
| CA2073601C (en) | 1996-07-09 |
| EP0547294A1 (de) | 1993-06-23 |
| DK0547294T3 (da) | 1995-12-18 |
| GR3018205T3 (en) | 1996-02-29 |
| ES2081531T3 (es) | 1996-03-16 |
| DE69206245T2 (de) | 1996-05-02 |
| ITBO910476A1 (it) | 1993-06-17 |
| US5314904A (en) | 1994-05-24 |
| DE69206245D1 (de) | 1996-01-04 |
| JPH05255085A (ja) | 1993-10-05 |
| TW217385B (de) | 1993-12-11 |
| MX9204132A (es) | 1993-08-01 |
| CA2073601A1 (en) | 1993-06-18 |
| KR0149519B1 (ko) | 1998-10-15 |
| ITBO910476A0 (it) | 1991-12-17 |
| EP0547294B1 (de) | 1995-11-22 |
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