DK0951473T3 - Cyclosporinderivat, fremstilling af dette og farmaceutiske præparater indeholdende dette - Google Patents

Cyclosporinderivat, fremstilling af dette og farmaceutiske præparater indeholdende dette

Info

Publication number: DK0951473T3
Authority: DK; Denmark
Prior art keywords: preparation; pharmaceutical preparations; preparations containing; cyclosporin derivative; cyclosporin
Prior art date: 1996-12-24

Application number

DK97952997T

Other languages

English (en)

Inventor

Jean-Claude Barriere

Georges Bashiardes

Jean-Christophe Carry

Michel Evers

Bruno Filoche

Serge Mignani

Original Assignee

Aventis Pharma Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-12-24

Filing date

1997-12-23

Publication date

2002-09-16

1997-12-23 Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa

2002-09-16 Application granted granted Critical

2002-09-16 Publication of DK0951473T3 publication Critical patent/DK0951473T3/da

Links

PMATZTZNYRCHOR-CGLBZJNRSA-N Cyclosporin A Chemical class CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C1=O PMATZTZNYRCHOR-CGLBZJNRSA-N 0.000 title 1
239000000825 pharmaceutical preparation Substances 0.000 title 1
238000002360 preparation method Methods 0.000 title 1
229930105110 Cyclosporin A Natural products 0.000 abstract 1
108010036949 Cyclosporine Proteins 0.000 abstract 1
208000005074 Retroviridae Infections Diseases 0.000 abstract 1
229960001265 ciclosporin Drugs 0.000 abstract 1
229930182912 cyclosporin Natural products 0.000 abstract 1
-1 cyclosporin compound Chemical class 0.000 abstract 1
238000011321 prophylaxis Methods 0.000 abstract 1
238000011282 treatment Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/64—Cyclic peptides containing only normal peptide links
- C07K7/645—Cyclosporins; Related peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
General Health & Medical Sciences (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Genetics & Genomics (AREA)
Virology (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Communicable Diseases (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Oncology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Peptides Or Proteins (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

DK97952997T 1996-12-24 1997-12-23 Cyclosporinderivat, fremstilling af dette og farmaceutiske præparater indeholdende dette DK0951473T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR9615954A FR2757520B1 (fr)	1996-12-24	1996-12-24	Derive de cyclosporine, sa preparation et les compositions pharmaceutiques qui le contiennent
PCT/FR1997/002404 WO1998028328A1 (fr)	1996-12-24	1997-12-23	Derive de cyclosporine, sa preparation et les compositions pharmaceutiques qui le contiennent

Publications (1)

Publication Number	Publication Date
DK0951473T3 true DK0951473T3 (da)	2002-09-16

Family

ID=9499087

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK97952997T DK0951473T3 (da)	1996-12-24	1997-12-23	Cyclosporinderivat, fremstilling af dette og farmaceutiske præparater indeholdende dette

Country Status (11)

Country	Link
US (1)	US5948755A (da)
EP (1)	EP0951473B1 (da)
JP (1)	JP4104666B2 (da)
AT (1)	ATE218581T1 (da)
AU (1)	AU5669198A (da)
DE (1)	DE69713151D1 (da)
DK (1)	DK0951473T3 (da)
ES (1)	ES2178036T3 (da)
FR (1)	FR2757520B1 (da)
PT (1)	PT951473E (da)
WO (1)	WO1998028328A1 (da)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20030220234A1 (en)	1998-11-02	2003-11-27	Selvaraj Naicker	Deuterated cyclosporine analogs and their use as immunodulating agents
PT1086124E (pt) *	1998-06-12	2004-04-30	Chem Ag C	Ciclosporinas novas
PT1091975E (pt)	1998-07-01	2006-05-31	Debiopharm Sa	Nova ciclosporina com um perfil de actividade melhorado
US6254860B1 (en) *	1999-04-13	2001-07-03	Allergan Sales, Inc.	Ocular treatment using cyclosporin-A derivatives
HRP20040354B1 (en) *	2001-10-19	2012-10-31	Isotechnika Inc.	Novel cyclosporin analog microemulsion preconcentrates
US7141648B2 (en)	2001-10-19	2006-11-28	Isotechnika Inc.	Synthesis of cyclosporin analogs
KR100512019B1 (ko) *	2002-07-25	2005-09-02	신득용	사이클로스포린 ａ 또는 이의 유도체를 이용한 세포의노화를 억제하는 방법 및 배양배지
EP1603512A2 (en)	2003-03-17	2005-12-14	Albany Molecular Research, Inc.	Novel cyclosporins
GB0320638D0 (en)	2003-09-03	2003-10-01	Novartis Ag	Organic compounds
EP1692112A4 (en) *	2003-12-08	2008-09-24	Cytokinetics Inc	COMPOUNDS, COMPOSITIONS, AND METHODS
WO2006039164A2 (en)	2004-09-29	2006-04-13	Amr Technology, Inc.	Novel cyclosporin analogues and their pharmaceutical uses
US7378391B2 (en)	2004-09-29	2008-05-27	Amr Technology, Inc.	Cyclosporin alkyne analogues and their pharmaceutical uses
US7196161B2 (en)	2004-10-01	2007-03-27	Scynexis Inc.	3-ether and 3-thioether substituted cyclosporin derivatives for the treatment and prevention of hepatitis C infection
KR101309409B1 (ko) *	2004-10-01	2013-09-23	싸이넥시스, 인크.	Ｃ형 간염 바이러스 감염의 치료 및 예방을 위한 ３-에테르및 ３-티오에테르 치환된 시클로스포린 유도체
BRPI0515494A (pt)	2004-10-01	2008-07-29	Debiopharm Sa	uso de [d-meala] 3-[etval] 4-ciclosporina para o tratamento de infecção por hepatite c e composição farmacêutica compreendendo a referida [d-meala] 3-[etval] 4-ciclosporina
WO2006041631A2 (en)	2004-10-06	2006-04-20	Amr Technology, Inc.	Novel cyclosporin alkynes and their utility as pharmaceutical agents
DE602006020152D1 (de) *	2005-09-30	2011-03-31	Scynexis Inc	Arylalkyl- und heteroarylalkyl-derivate von cyclosporin a bei der behandlung und vorbeugung einer virusinfektion
KR20080059270A (ko)	2005-09-30	2008-06-26	싸이넥시스, 인크.	Ｃ형 간염 감염의 치료 및 예방을 위한 방법 및 제약조성물
US7696165B2 (en)	2006-03-28	2010-04-13	Albany Molecular Research, Inc.	Use of cyclosporin alkyne analogues for preventing or treating viral-induced disorders
US7696166B2 (en)	2006-03-28	2010-04-13	Albany Molecular Research, Inc.	Use of cyclosporin alkyne/alkene analogues for preventing or treating viral-induced disorders
DK2023918T3 (da)	2006-05-19	2011-04-26	Scynexis Inc	Cyclosporiner til behandlingen og forebyggelse af okulære lidelser
JP2009539292A (ja) *	2006-06-02	2009-11-12	ぺリション、クロード、アニー	活性電子の管理
WO2008069917A2 (en)	2006-11-20	2008-06-12	Scynexis, Inc.	Novel cyclic peptides
WO2008127613A1 (en) *	2007-04-11	2008-10-23	Scynexis, Inc.	New pharmaceutical compositions
US8394763B2 (en)	2007-09-26	2013-03-12	Oregon Health & Science University	Cyclic undecapeptides and derivatives as multiple sclerosis therapies
JP5820722B2 (ja)	2008-06-06	2015-11-24	スシネキスインク	シクロスポリン類似体及びｈｃｖ感染の治療におけるその使用
WO2009148615A1 (en) *	2008-06-06	2009-12-10	Scynexis, Inc.	Cyclosporin analogs and their use in the treatment of hcv infections
KR20110031973A (ko) *	2008-07-10	2011-03-29	알러간, 인코포레이티드	눈 및 피부의 질환 및 상태를 치료하기 위한 사이클로스포린 유도체
US8536114B2 (en)	2008-12-31	2013-09-17	Scynexis, Inc.	Macrocycles
WO2010138423A1 (en) *	2009-05-27	2010-12-02	Allergan, Inc.	Cyclosporin derivatives for treating inflammatory diseases and conditions
KR101149529B1 (ko)	2009-09-11	2012-05-25	한국화학연구원	인덴온 유도체 및 이를 포함하는 약학적 조성물
KR20120125610A (ko)	2009-12-30	2012-11-16	싸이넥시스, 인크.	시클로스포린 유사체
WO2012079172A1 (en)	2010-12-15	2012-06-21	Isotechnika Pharma Inc.	Cyclosporine analogue molecules modified at amino acid 1 and 3
US9395551B2 (en)	2013-04-24	2016-07-19	Kamakura Koki Co., Ltd.	Optical image stabilizer
TW201902507A (zh) *	2017-04-14	2019-01-16	美商康特維爾製藥公司	治療病毒感染之組合療法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0194972B1 (en) *	1985-03-11	1992-07-29	Sandoz Ag	Novel cyclosporins
US4814323A (en) *	1986-03-25	1989-03-21	Andrieu J M	Process for the treatment and the prevention of AIDS and other disorders induced by the LAV/HTLV III virus
DE69124459T3 (de) *	1990-11-02	2001-05-31	Novartis Ag, Basel	Zyklosporine
ATE209216T1 (de) *	1995-07-17	2001-12-15	Chem Ag C	Cyclosporin-derivate mit anti-hiv-wirkung

1996
- 1996-12-24 FR FR9615954A patent/FR2757520B1/fr not_active Expired - Fee Related
1997
- 1997-12-23 ES ES97952997T patent/ES2178036T3/es not_active Expired - Lifetime
- 1997-12-23 PT PT97952997T patent/PT951473E/pt unknown
- 1997-12-23 WO PCT/FR1997/002404 patent/WO1998028328A1/fr not_active Ceased
- 1997-12-23 DE DE69713151T patent/DE69713151D1/de not_active Expired - Lifetime
- 1997-12-23 EP EP97952997A patent/EP0951473B1/fr not_active Expired - Lifetime
- 1997-12-23 AT AT97952997T patent/ATE218581T1/de active
- 1997-12-23 JP JP52848898A patent/JP4104666B2/ja not_active Expired - Fee Related
- 1997-12-23 US US08/997,613 patent/US5948755A/en not_active Expired - Fee Related
- 1997-12-23 AU AU56691/98A patent/AU5669198A/en not_active Abandoned
- 1997-12-23 DK DK97952997T patent/DK0951473T3/da active

Also Published As

Publication number	Publication date
JP2001507016A (ja)	2001-05-29
EP0951473B1 (fr)	2002-06-05
US5948755A (en)	1999-09-07
DE69713151D1 (de)	2002-07-11
AU5669198A (en)	1998-07-17
EP0951473A1 (fr)	1999-10-27
FR2757520A1 (fr)	1998-06-26
FR2757520B1 (fr)	1999-01-29
JP4104666B2 (ja)	2008-06-18
PT951473E (pt)	2002-11-29
ATE218581T1 (de)	2002-06-15
ES2178036T3 (es)	2002-12-16
WO1998028328A1 (fr)	1998-07-02

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