ATE130760T1 - Synergistische wechselwirkung von interleukin-2 und doppelsträngiger rns. - Google Patents

Synergistische wechselwirkung von interleukin-2 und doppelsträngiger rns.

Info

Publication number
ATE130760T1
ATE130760T1 AT88301821T AT88301821T ATE130760T1 AT E130760 T1 ATE130760 T1 AT E130760T1 AT 88301821 T AT88301821 T AT 88301821T AT 88301821 T AT88301821 T AT 88301821T AT E130760 T1 ATE130760 T1 AT E130760T1
Authority
AT
Austria
Prior art keywords
lymphokines
dsrna
human
interleukin
double
Prior art date
Application number
AT88301821T
Other languages
English (en)
Inventor
William A Carter
Original Assignee
Hem Pharma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hem Pharma Corp filed Critical Hem Pharma Corp
Application granted granted Critical
Publication of ATE130760T1 publication Critical patent/ATE130760T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A61K38/212—IFN-alpha
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A61K38/2013—IL-2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Communicable Diseases (AREA)
  • Rheumatology (AREA)
  • Oncology (AREA)
  • Pain & Pain Management (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cosmetics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines Containing Plant Substances (AREA)
AT88301821T 1987-03-03 1988-03-02 Synergistische wechselwirkung von interleukin-2 und doppelsträngiger rns. ATE130760T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US2136887A 1987-03-03 1987-03-03

Publications (1)

Publication Number Publication Date
ATE130760T1 true ATE130760T1 (de) 1995-12-15

Family

ID=21803798

Family Applications (1)

Application Number Title Priority Date Filing Date
AT88301821T ATE130760T1 (de) 1987-03-03 1988-03-02 Synergistische wechselwirkung von interleukin-2 und doppelsträngiger rns.

Country Status (19)

Country Link
EP (1) EP0281380B1 (de)
JP (1) JPH0713024B2 (de)
KR (1) KR960008009B1 (de)
CN (1) CN1054509C (de)
AT (1) ATE130760T1 (de)
AU (2) AU1256588A (de)
CA (1) CA1336810C (de)
DE (1) DE3854726T2 (de)
DK (1) DK113188A (de)
ES (1) ES2082749T3 (de)
FI (1) FI880961A7 (de)
IE (1) IE75895B1 (de)
IL (1) IL85603A (de)
NO (1) NO880946L (de)
NZ (1) NZ223720A (de)
PH (1) PH24467A (de)
PT (1) PT86879B (de)
RU (1) RU1836103C (de)
ZA (1) ZA881512B (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA881639B (en) * 1987-03-23 1989-02-22 Hem Res Inc Treatment of human viral infection by dsrna combined with viral inhibitors
ES2076259T3 (es) * 1989-06-30 1995-11-01 American Cyanamid Co Metodo para el tratamiento de enfermedades infecciosas activando celulas fagociticas en animales.
TW589189B (en) 1997-08-04 2004-06-01 Scras Kit containing at least one double-stranded RNA combined with at least one anti-viral agent for therapeutic use in the treatment of a viral disease, notably of viral hepatitis
FR2768344B1 (fr) * 1997-08-26 2001-02-16 Scras Produit comprenant au moins un arn double brin en association avec au moins un agent anti-viral pour une utilisation therapeutique dans le traitement d'une maladie virale
FR2768345B1 (fr) * 1997-09-17 2001-05-04 Scras Produit comprenant au moins un arn double brin en association avec au moins un agent anti-viral pour une utilisation therapeutique dans le traitement d'une maladie virale, notamment d'une hepatite virale
FR2766715B1 (fr) * 1997-08-04 2001-02-16 Scras Produit comprenant au moins de l'arn double brin en association avec au moins un agent anti-viral pour une utilisation therapeutique simultanee, separee ou etalee dans le temps, dans le traitement d'une maladie virale
US6506559B1 (en) 1997-12-23 2003-01-14 Carnegie Institute Of Washington Genetic inhibition by double-stranded RNA
AUPP249298A0 (en) 1998-03-20 1998-04-23 Ag-Gene Australia Limited Synthetic genes and genetic constructs comprising same I
CN101818145A (zh) 1998-03-20 2010-09-01 联邦科学和工业研究组织 控制基因表达
AU776150B2 (en) 1999-01-28 2004-08-26 Medical College Of Georgia Research Institute, Inc. Composition and method for (in vivo) and (in vitro) attenuation of gene expression using double stranded RNA
US6423885B1 (en) 1999-08-13 2002-07-23 Commonwealth Scientific And Industrial Research Organization (Csiro) Methods for obtaining modified phenotypes in plant cells
US20020132257A1 (en) 2001-01-31 2002-09-19 Tony Giordano Use of post-transcriptional gene silencing for identifying nucleic acid sequences that modulate the function of a cell
WO2006054129A1 (en) * 2004-11-19 2006-05-26 Institut Gustave Roussy Improved treatment of cancer by double-stranded rna
EP2116602A1 (de) 2008-05-07 2009-11-11 Institut Gustave Roussy Kombinationsprodukte zur Behandlung von Krebs
WO2011109833A2 (en) 2010-03-05 2011-09-09 President And Fellows Of Harvard College Induced dendritic cell compositions and uses thereof
CN106794246B (zh) 2014-08-08 2021-10-15 OncoQuest制药有限公司 肿瘤抗原特异性抗体和tlr3刺激以增强检查点干扰癌症疗法的性能
TW202308629A (zh) 2021-04-28 2023-03-01 法商Ｅｎｙｏ製藥公司 使用fxr激動劑作為組合治療以增強tlr3激動劑之療效

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0113162B1 (de) * 1982-09-16 1989-07-19 Hem Research, Inc. Wucherungshemmende Wirkung von ds-Ribonucleinsäuren auf Tumorzellen
CA1326450C (en) * 1985-08-26 1994-01-25 William A. Carter Modulation of aids virus-related events by double stranded rnas (dsrnas)

Also Published As

Publication number Publication date
IL85603A (en) 1993-05-13
EP0281380A3 (en) 1989-09-27
AU1256588A (en) 1988-09-01
NO880946L (no) 1988-09-05
CN1054509C (zh) 2000-07-19
PT86879B (pt) 1992-05-29
EP0281380A2 (de) 1988-09-07
JPS63295514A (ja) 1988-12-01
DE3854726T2 (de) 1996-07-25
RU1836103C (ru) 1993-08-23
NO880946D0 (no) 1988-03-03
FI880961L (fi) 1988-09-04
KR880010776A (ko) 1988-10-24
IL85603A0 (en) 1988-08-31
AU1618992A (en) 1992-08-06
NZ223720A (en) 1991-07-26
IE880588L (en) 1988-09-03
DE3854726D1 (de) 1996-01-11
PT86879A (pt) 1988-04-01
IE75895B1 (en) 1997-09-24
CN1032296A (zh) 1989-04-12
ES2082749T3 (es) 1996-04-01
JPH0713024B2 (ja) 1995-02-15
FI880961A0 (fi) 1988-03-02
PH24467A (en) 1990-07-18
FI880961A7 (fi) 1988-09-04
ZA881512B (en) 1988-11-30
CA1336810C (en) 1995-08-29
DK113188A (da) 1988-09-04
KR960008009B1 (ko) 1996-06-19
DK113188D0 (da) 1988-03-02
EP0281380B1 (de) 1995-11-29

Similar Documents

Publication Publication Date Title
DE3854726D1 (de) Synergistische Wechselwirkung von Interleukin-2 und doppelsträngiger RNS.
ATE73347T1 (de) Antivirales immunotherapeutisches mittel und dessen herstellung.
IL87621A0 (en) Conjugates of cytokines with immunoglobulins,their preparation and pharmaceutical compositions containing them
PT87039A (pt) Treatment of human viral infections by dsrna combined with viral inhibitors
ES2086623T3 (es) Azaheterociclilmetil-cromanos como principios activos para el tratamiento de enfermedades del sistema nervioso central.
EP0199479A3 (en) Ozone decontamination of blood and blood products
DK118286D0 (da) Terapeutisk aktive nucleosider, deres anvendelse og farmaceutiske kompositioner indeholdende forbindelserne
ES2099059T3 (es) Una composicion para promover el secuestro y extraccion del cuerpo de un animal de macromoleculas.
EP0296573A3 (en) Novel nucleosides, their preparation and pharmaceutical novel nucleosides, their preparation and pharmaceutical compositions compositions
EP0306347A3 (en) Diagnosis and treatment of double-stranded rna deficiency states
DE69833876D1 (de) Zusammensetzungen und methoden zur zielgerichteten abgabe von biologisch aktivenfaktoren
ES2036526T3 (es) Composiciones de interferon.
EP0325018A3 (de) RNase L Inhibitor als Markierung für Virusinfektion
BR9007741A (pt) Protecao contra estados de choque subsequentes a lesoes por rnas de duplo filamento
ES2037807T3 (es) Medicamentos que contienen en combinacion interferon y 1-desoxi-piperidinosas, procedimiento para su fabricacion y su aplicacion.
DE69106877D1 (de) Aus blaualgen hergestellte biologisch aktive verbindungen.
EP1013763A4 (de) Interleukin 18 und interleukin 18-convertase des hundes, dafür kodierende dns-moleküle, verfahren für die produktion von interleukin 18 und mittel zur behandlung von erkrankungen des immunsystems beim hund.
DE3462891D1 (en) New pyrimidine derivatives endowed with antiviral activity
SU1727820A1 (ru) Способ стимул ции сперматогенеза у быков
EP0343258A4 (de) Mittel zur prophylaxe und behandlung von viralen infektionskrankheiten.
JO1708B1 (en) The use of trinitrobenzene or cochineal acid in the treatment of cancer or genital diseases

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee