ATE131074T1 - Festes matrixsystem zur transdermalen arzneimittelfreisetzung. - Google Patents
Festes matrixsystem zur transdermalen arzneimittelfreisetzung.Info
- Publication number
- ATE131074T1 ATE131074T1 AT90309608T AT90309608T ATE131074T1 AT E131074 T1 ATE131074 T1 AT E131074T1 AT 90309608 T AT90309608 T AT 90309608T AT 90309608 T AT90309608 T AT 90309608T AT E131074 T1 ATE131074 T1 AT E131074T1
- Authority
- AT
- Austria
- Prior art keywords
- drug release
- release matrix
- transdermal drug
- matrix system
- matrix
- Prior art date
Links
- 239000011159 matrix material Substances 0.000 title abstract 4
- 229940079593 drug Drugs 0.000 title abstract 2
- 239000003814 drug Substances 0.000 title abstract 2
- 239000007787 solid Substances 0.000 title 1
- 238000012377 drug delivery Methods 0.000 abstract 2
- VOXZDWNPVJITMN-ZBRFXRBCSA-N 17β-estradiol Chemical compound OC1=CC=C2[C@H]3CC[C@](C)([C@H](CC4)O)[C@@H]4[C@@H]3CCC2=C1 VOXZDWNPVJITMN-ZBRFXRBCSA-N 0.000 abstract 1
- 239000000853 adhesive Substances 0.000 abstract 1
- 229920001577 copolymer Polymers 0.000 abstract 1
- 239000003623 enhancer Substances 0.000 abstract 1
- 229960005309 estradiol Drugs 0.000 abstract 1
- 229930182833 estradiol Natural products 0.000 abstract 1
- 150000003431 steroids Chemical class 0.000 abstract 1
- 230000037317 transdermal delivery Effects 0.000 abstract 1
- 229920003169 water-soluble polymer Polymers 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
- A61K9/7061—Polyacrylates
Landscapes
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Dermatology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Materials For Medical Uses (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US40563089A | 1989-09-08 | 1989-09-08 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE131074T1 true ATE131074T1 (de) | 1995-12-15 |
Family
ID=23604513
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT90309608T ATE131074T1 (de) | 1989-09-08 | 1990-09-03 | Festes matrixsystem zur transdermalen arzneimittelfreisetzung. |
Country Status (15)
| Country | Link |
|---|---|
| EP (1) | EP0416842B1 (de) |
| JP (3) | JP2718433B2 (de) |
| AT (1) | ATE131074T1 (de) |
| AU (1) | AU644815B2 (de) |
| CA (1) | CA2065311C (de) |
| DE (1) | DE69023992T2 (de) |
| DK (1) | DK0416842T3 (de) |
| ES (1) | ES2081352T3 (de) |
| FI (1) | FI107708B (de) |
| GR (1) | GR3019124T3 (de) |
| IE (1) | IE71048B1 (de) |
| NO (1) | NO303262B1 (de) |
| NZ (1) | NZ235068A (de) |
| PT (1) | PT95245B (de) |
| WO (1) | WO1991003219A1 (de) |
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5560922A (en) * | 1986-05-30 | 1996-10-01 | Rutgers, The State University Of New Jersey | Transdermal absorption dosage unit using a polyacrylate adhesive polymer and process |
| US6110488A (en) * | 1986-08-28 | 2000-08-29 | Lts Lohmann Therapie-Systeme Gmbh & Co. Kg | Transdermal therapeutic system, its use and production process |
| US6117448A (en) * | 1986-08-28 | 2000-09-12 | Lts Lohmann Therapie-Systeme Gmbh & Co. Kg | Transdermal therapeutic system, its use and production process |
| US6139868A (en) * | 1986-08-28 | 2000-10-31 | Lts Lohmann Therapie-Systeme Gmbh & Co. Kg | Transdermal therapeutic system, its use and production process |
| US6126963A (en) | 1986-08-28 | 2000-10-03 | Lts Lohmann Therapie-Systeme Gmbh & Co. Kg | Transdermal therapeutic system, its use and production process |
| USRE37934E1 (en) | 1986-08-28 | 2002-12-10 | Lts Lohmann Therapie-Systeme Ag | Transdermal therapeutic system |
| US5820876A (en) * | 1986-08-28 | 1998-10-13 | Lts Lohmann Therapie-Systeme Gmbh & Co. Kg | Transdermal therapeutic system |
| US5474783A (en) * | 1988-03-04 | 1995-12-12 | Noven Pharmaceuticals, Inc. | Solubility parameter based drug delivery system and method for altering drug saturation concentration |
| US5656286A (en) * | 1988-03-04 | 1997-08-12 | Noven Pharmaceuticals, Inc. | Solubility parameter based drug delivery system and method for altering drug saturation concentration |
| US5246706A (en) * | 1991-07-19 | 1993-09-21 | Cygnus Therapeutic Systems | Device for administering bimakalim transdermally |
| DE4229820C2 (de) * | 1992-09-07 | 1998-12-03 | Jenapharm Gmbh | Pharmazeutische Zubereitung auf Gestagen-Basis |
| US5919478A (en) * | 1993-06-25 | 1999-07-06 | Alza Corporation | Incorporating poly-N-vinyl amide in a transdermal system |
| US5460820B1 (en) † | 1993-08-03 | 1999-08-03 | Theratech Inc | Method for providing testosterone and optionally estrogen replacement therapy to women |
| US5554381A (en) * | 1993-08-09 | 1996-09-10 | Cygnus, Inc. | Low flux matrix system for delivering potent drugs transdermally |
| DE4333595A1 (de) * | 1993-10-01 | 1995-04-06 | Labtec Gmbh | Transdermales therapeutisches System zur Applikation von Arzneimitteln auf die Haut |
| GR1002079B (en) * | 1994-07-26 | 1995-12-05 | Lavipharm A E | System of a special structure and composition for the rapid transdermal administration of oestrogens. |
| WO1996008255A1 (en) * | 1994-09-14 | 1996-03-21 | Minnesota Mining And Manufacturing Company | Transdermal device for delivery of levonorgestrel |
| US5780050A (en) * | 1995-07-20 | 1998-07-14 | Theratech, Inc. | Drug delivery compositions for improved stability of steroids |
| DE19526864A1 (de) * | 1995-07-22 | 1997-01-23 | Labtec Gmbh | Hormonpflaster |
| DE19548332A1 (de) * | 1995-12-22 | 1997-07-10 | Rotta Res Bv | Hormonpflaster |
| DE19631084A1 (de) | 1996-08-01 | 1998-02-05 | Basf Ag | Verwendung von (Meth)acrylsäure-Copolymeren zur Erhöhung der Permeabilität der Schleimhaut |
| DE19701949A1 (de) * | 1997-01-13 | 1998-07-16 | Jenapharm Gmbh | Transdermales therapeutisches System |
| JP4477152B2 (ja) * | 1997-05-16 | 2010-06-09 | 株式会社共和 | ストーマ用又は瘡傷用の皮膚保護材 |
| DE19827732A1 (de) * | 1998-06-22 | 1999-12-23 | Rottapharm Bv | Transdermales System vom Matrix-Typ zur Abgabe von Wirkstoffen mit einer hohen Abgaberate von Steroid-Hormonen und die Verwendung eines derartigen Systems zur Hormonersatztherapie |
| DE19834007C1 (de) * | 1998-07-29 | 2000-02-24 | Lohmann Therapie Syst Lts | Estradiolhaltiges Pflaster zur transdermalen Applikation von Hormonen und seine Verwendung |
| JP3528739B2 (ja) | 2000-02-16 | 2004-05-24 | 日産自動車株式会社 | エンジンの排気浄化装置 |
| US20020119187A1 (en) * | 2000-09-29 | 2002-08-29 | Cantor Adam S. | Composition for the transdermal delivery of fentanyl |
| JP3935839B2 (ja) * | 2000-11-17 | 2007-06-27 | 帝三製薬株式会社 | エストラジオール含有貼付剤 |
| ES2270746T3 (es) * | 2001-03-16 | 2007-12-01 | Alza Corporation | Parche transdermico para administrar fentanilo. |
| DE10141652B4 (de) * | 2001-08-24 | 2011-04-07 | Lts Lohmann Therapie-Systeme Ag | Transdermales therapeutisches System auf der Basis von Polyacrylat-Haftklebern ohne funktionelle Gruppen und seine Verwendung |
| DE10141650C1 (de) * | 2001-08-24 | 2002-11-28 | Lohmann Therapie Syst Lts | Transdermales Therapeutisches System mit Fentanyl bzw. verwandten Substanzen |
| JP4194277B2 (ja) | 2002-01-25 | 2008-12-10 | 久光製薬株式会社 | 架橋ポリマーを主成分とする粘着性成形体の製造方法 |
| WO2006064747A1 (ja) | 2004-12-15 | 2006-06-22 | Saitama Daiichi Pharmaceutical Co., Ltd. | 医療用テープ剤 |
| DE102004062182B4 (de) * | 2004-12-20 | 2007-06-06 | Bayer Schering Pharma Ag | Transdermales Pflaster mit Progesteron A-Spezifische Liganden (PRASL) als Wirkstoff |
| EP2255809B1 (de) | 2008-02-27 | 2017-08-23 | Hisamitsu Pharmaceutical Co., Inc. | Mit arzneistoff versetztes pflaster |
| FR2992325B1 (fr) | 2012-06-26 | 2015-05-22 | Ab7 Innovation | Matrice sequencee multifonctionnelle monopolymerique en polyurethane coule et procede de fabrication |
| JP6125547B2 (ja) * | 2013-04-24 | 2017-05-10 | あすか製薬株式会社 | 無定形レボノルゲストレル、固体分散体及びそれらの製造方法 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3632740A (en) * | 1968-06-13 | 1972-01-04 | Johnson & Johnson | Topical device for the therapeutic management of dermatological lesions with steroids |
| US3769071A (en) * | 1971-06-04 | 1973-10-30 | Minnesota Mining & Mfg | Pressure sensitive adhesive tape comprising 5-fluorouracil |
| US3896789A (en) * | 1974-06-10 | 1975-07-29 | Riker Laboratories Inc | Retinoic acid dipensing pressure sensitive dermotological tape |
| JPS5843368B2 (ja) * | 1980-10-30 | 1983-09-27 | 日東電工株式会社 | 消炎鎮痛貼付剤 |
| JPS57142258A (en) * | 1981-02-27 | 1982-09-02 | Nitto Electric Ind Co | Drug containing tape preparation |
| JPS57179271A (en) * | 1981-04-28 | 1982-11-04 | Sekisui Chem Co Ltd | Remedial adhesive tape or sheet |
| JPS6066759A (ja) * | 1983-09-21 | 1985-04-16 | 日東電工株式会社 | 医薬製剤 |
| JPS60123417A (ja) * | 1983-12-07 | 1985-07-02 | Nitto Electric Ind Co Ltd | 薬物投与部材 |
| GB2156215B (en) * | 1984-03-05 | 1988-03-02 | Nitto Electric Ind Co | Percutaneous absorption type adhesive pharmaceutical preparation |
| US4655768A (en) * | 1984-07-06 | 1987-04-07 | Avery International Corporation | Bandage for sustained delivery of drugs |
| ATE59302T1 (de) * | 1984-07-24 | 1991-01-15 | Key Pharma | Klebende schicht zur transdermalen freigabe. |
| AU563054B2 (en) * | 1984-10-24 | 1987-06-25 | Sekisui Kagaku Kogyo Kabushiki Kaisha | Percutaneous tape of isdn |
| JPS61280426A (ja) * | 1985-06-04 | 1986-12-11 | Ikeda Mohandou:Kk | 消炎鎮痛用貼付剤 |
| DE3682165D1 (de) * | 1985-11-08 | 1991-11-28 | Nitto Denko Corp | Verwendung von heftpflastern fuer die haut und perkutanen praeparaten. |
| US4759816A (en) * | 1986-07-07 | 1988-07-26 | Schoeller Technical Papers, Inc. | Strippable film for adhesive coating and laminating |
| US4906475A (en) * | 1988-02-16 | 1990-03-06 | Paco Pharmaceutical Services | Estradiol transdermal delivery system |
| DE68917292T2 (de) * | 1988-02-26 | 1995-02-02 | Riker Laboratories Inc | Transdermales estradiol als therapeutisches sytem. |
-
1990
- 1990-08-22 CA CA002065311A patent/CA2065311C/en not_active Expired - Lifetime
- 1990-08-22 WO PCT/US1990/004767 patent/WO1991003219A1/en not_active Ceased
- 1990-08-22 JP JP2513705A patent/JP2718433B2/ja not_active Expired - Lifetime
- 1990-08-22 AU AU64415/90A patent/AU644815B2/en not_active Ceased
- 1990-08-28 NZ NZ235068A patent/NZ235068A/xx unknown
- 1990-09-03 DK DK90309608.9T patent/DK0416842T3/da active
- 1990-09-03 EP EP90309608A patent/EP0416842B1/de not_active Revoked
- 1990-09-03 ES ES90309608T patent/ES2081352T3/es not_active Expired - Lifetime
- 1990-09-03 DE DE69023992T patent/DE69023992T2/de not_active Revoked
- 1990-09-03 AT AT90309608T patent/ATE131074T1/de not_active IP Right Cessation
- 1990-09-07 IE IE325990A patent/IE71048B1/en not_active IP Right Cessation
- 1990-09-07 PT PT95245A patent/PT95245B/pt not_active IP Right Cessation
-
1992
- 1992-03-03 NO NO920832A patent/NO303262B1/no not_active IP Right Cessation
- 1992-03-04 FI FI920960A patent/FI107708B/fi active
-
1996
- 1996-02-28 GR GR960400548T patent/GR3019124T3/el unknown
- 1996-07-24 JP JP8195013A patent/JP2974969B2/ja not_active Expired - Lifetime
-
1999
- 1999-06-16 JP JP11170346A patent/JP2000026284A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| DE69023992D1 (de) | 1996-01-18 |
| CA2065311A1 (en) | 1991-03-09 |
| JPH05500510A (ja) | 1993-02-04 |
| JP2718433B2 (ja) | 1998-02-25 |
| EP0416842B1 (de) | 1995-12-06 |
| AU644815B2 (en) | 1993-12-23 |
| WO1991003219A1 (en) | 1991-03-21 |
| JP2974969B2 (ja) | 1999-11-10 |
| FI920960A0 (fi) | 1992-03-04 |
| PT95245B (pt) | 2001-05-31 |
| IE71048B1 (en) | 1997-01-15 |
| JP2000026284A (ja) | 2000-01-25 |
| EP0416842A1 (de) | 1991-03-13 |
| IE903259A1 (en) | 1991-03-13 |
| DK0416842T3 (da) | 1996-01-02 |
| GR3019124T3 (en) | 1996-05-31 |
| NO920832D0 (no) | 1992-03-03 |
| NO920832L (no) | 1992-03-03 |
| CA2065311C (en) | 2000-01-11 |
| JPH09100227A (ja) | 1997-04-15 |
| NO303262B1 (no) | 1998-06-22 |
| NZ235068A (en) | 1993-05-26 |
| AU6441590A (en) | 1991-04-08 |
| FI107708B (fi) | 2001-09-28 |
| PT95245A (pt) | 1991-08-14 |
| DE69023992T2 (de) | 1996-04-25 |
| ES2081352T3 (es) | 1996-03-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RZN | Patent revoked |