ATE132858T1 - 4-cinnolinon-derivate, ihre herstellung und ihre verwendung als arzneimittel - Google Patents

4-cinnolinon-derivate, ihre herstellung und ihre verwendung als arzneimittel

Info

Publication number: ATE132858T1
Authority: AT; Austria
Prior art keywords: alkyl; denotes; phenyl; alkyl radical; hydrogen
Prior art date: 1991-11-04

Application number

AT92924754T

Other languages

English (en)

Inventor

Jean-Francois Patoiseau

Jean-Marie Autin

Jean-Louis Maurel

Dennis Bigg

Original Assignee

Pf Medicament

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-11-04

Filing date

1992-11-03

Publication date

1996-01-15

1992-11-03 Application filed by Pf Medicament filed Critical Pf Medicament

1996-01-15 Application granted granted Critical

1996-01-15 Publication of ATE132858T1 publication Critical patent/ATE132858T1/de

Links

SLGVJLNVPYQNNK-UHFFFAOYSA-N 3h-cinnolin-4-one Chemical class C1=CC=C2C(=O)CN=NC2=C1 SLGVJLNVPYQNNK-UHFFFAOYSA-N 0.000 title abstract 2
229940126601 medicinal product Drugs 0.000 title 1
125000000217 alkyl group Chemical group 0.000 abstract 5
239000001257 hydrogen Substances 0.000 abstract 5
229910052739 hydrogen Inorganic materials 0.000 abstract 5
125000003545 alkoxy group Chemical group 0.000 abstract 4
229910052736 halogen Inorganic materials 0.000 abstract 4
150000002367 halogens Chemical class 0.000 abstract 4
150000002431 hydrogen Chemical class 0.000 abstract 4
125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 4
RWRDLPDLKQPQOW-UHFFFAOYSA-N Pyrrolidine Chemical compound C1CCNC1 RWRDLPDLKQPQOW-UHFFFAOYSA-N 0.000 abstract 3
YNAVUWVOSKDBBP-UHFFFAOYSA-N Morpholine Chemical compound C1COCCN1 YNAVUWVOSKDBBP-UHFFFAOYSA-N 0.000 abstract 2
GLUUGHFHXGJENI-UHFFFAOYSA-N Piperazine Chemical compound C1CNCCN1 GLUUGHFHXGJENI-UHFFFAOYSA-N 0.000 abstract 2
NQRYJNQNLNOLGT-UHFFFAOYSA-N Piperidine Chemical compound C1CCNCC1 NQRYJNQNLNOLGT-UHFFFAOYSA-N 0.000 abstract 2
CIUQDSCDWFSTQR-UHFFFAOYSA-N [C]1=CC=CC=C1 Chemical compound [C]1=CC=CC=C1 CIUQDSCDWFSTQR-UHFFFAOYSA-N 0.000 abstract 2
125000003342 alkenyl group Chemical group 0.000 abstract 2
125000004103 aminoalkyl group Chemical group 0.000 abstract 2
125000003118 aryl group Chemical group 0.000 abstract 2
150000001875 compounds Chemical class 0.000 abstract 2
125000002768 hydroxyalkyl group Chemical group 0.000 abstract 2
239000008194 pharmaceutical composition Substances 0.000 abstract 2
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
125000005037 alkyl phenyl group Chemical group 0.000 abstract 1
QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
125000000623 heterocyclic group Chemical group 0.000 abstract 1
229910052757 nitrogen Inorganic materials 0.000 abstract 1
125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
239000001301 oxygen Substances 0.000 abstract 1
229910052760 oxygen Inorganic materials 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
- C07D237/28—Cinnolines

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Pulmonology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Pyridine Compounds (AREA)

AT92924754T 1991-11-04 1992-11-03 4-cinnolinon-derivate, ihre herstellung und ihre verwendung als arzneimittel ATE132858T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR919113571A FR2683221B1 (fr)	1991-11-04	1991-11-04	Nouveaux derives de cinnolinones-4, leur preparation et leur application en therapeutique.

Publications (1)

Publication Number	Publication Date
ATE132858T1 true ATE132858T1 (de)	1996-01-15

Family

ID=9418583

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT92924754T ATE132858T1 (de)	1991-11-04	1992-11-03	4-cinnolinon-derivate, ihre herstellung und ihre verwendung als arzneimittel

Country Status (6)

Country	Link
EP (1)	EP0613470B1 (de)
JP (1)	JPH07507764A (de)
AT (1)	ATE132858T1 (de)
DE (1)	DE69207609D1 (de)
FR (1)	FR2683221B1 (de)
WO (1)	WO1993009098A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20060079544A1 (en) *	2004-08-13	2006-04-13	Boehringer Ingelheim International Gmbh	Medicaments for the prevention or treatment of alveolar pneumonia comprising an anticholinergic
CA2750708A1 (en) *	2009-02-23	2010-08-26	Merck Sharp & Dohme Corp.	Pyrazolo [4,3-c] cinnolin-3-one m1 receptor positive allosteric modulators
FR2950055A1 (fr)	2009-09-17	2011-03-18	Sanofi Aventis	Derives de 3-amino-cinnolin-4(1h)-one substitues, leur preparation et leur application en therapeutique
US11192900B2 (en) *	2018-10-30	2021-12-07	Nuvation Bio Inc.	Substituted 1,6-dihydropyridinones and 1,2-dihydroisoquinolinones as bet inhibitors

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3937704A (en) *	1971-10-18	1976-02-10	Warner-Lambert Company	3-(methylsulfinyl)cinnolinones and their derivatives
GB8702288D0 (en) *	1987-02-02	1987-03-11	Erba Farmitalia	Cinnoline-carboxamides

1991
- 1991-11-04 FR FR919113571A patent/FR2683221B1/fr not_active Expired - Fee Related
1992
- 1992-11-03 JP JP5508210A patent/JPH07507764A/ja active Pending
- 1992-11-03 EP EP92924754A patent/EP0613470B1/de not_active Expired - Lifetime
- 1992-11-03 DE DE69207609T patent/DE69207609D1/de not_active Expired - Lifetime
- 1992-11-03 AT AT92924754T patent/ATE132858T1/de not_active IP Right Cessation
- 1992-11-03 WO PCT/FR1992/001019 patent/WO1993009098A1/fr not_active Ceased

Also Published As

Publication number	Publication date
DE69207609D1 (de)	1996-02-22
JPH07507764A (ja)	1995-08-31
EP0613470B1 (de)	1996-01-10
FR2683221A1 (fr)	1993-05-07
FR2683221B1 (fr)	1994-03-04
WO1993009098A1 (fr)	1993-05-13
EP0613470A1 (de)	1994-09-07

Similar Documents

Publication	Publication Date	Title
ATE169008T1 (de)	1998-08-15	3,5-dioxo-(2h,4h)-1,2,4-triazinderivate ihre herstellung und verwendung als medikament
IL88122A0 (en)	1989-06-30	Heterocyclic derivatives and pharmaceutical compositions containing them
CA2282890A1 (en)	1991-12-08	Therapeutic heterocyclic compounds
YU56192A (sh)	1994-11-15	Heterociklični derivati
BG100154A (en)	1996-07-31	Carbazole derivatibes having inhibiting effect to 17,20-lyase
IL108259A0 (en)	1994-04-12	Piperazine derivates, their preparation and pharmaceutical compositions containing them
ES2036926A1 (es)	1993-06-01	"procedimiento para la obtencion de derivados de la (2-alquil-3-piridil)metilpiperazina".
ATE74352T1 (de)	1992-04-15	Dekahydrochinolinderivate, verfahren zu ihrer herstellung, zwischenprodukte zu ihrer herstellung, ihre verwendung als arzneimittel und diese enthaltende zubereitungen.
ATE101612T1 (de)	1994-03-15	Serotonin-antagonisten, ihre herstellung und sie enthaltende arzneimittel.
EA200300044A1 (ru)	2003-06-26	Новые замещенные фталиды, способ их получения и содержащие их фармацевтические композиции
DE69227088D1 (de)	1998-10-29	Verwendung von 1-(aminoalkyl)-3-Quinoxalin-2-on Derivaten zur Herstellung von neuroprotektiven Mitteln
GR1002281B (el)	1996-05-02	Παραγωγα 3(2η)-πυριδαζινονης και μεθοδος για την παρασκευη τους.
FI911925A0 (fi)	1991-04-19	Aminderivat.
ES479820A1 (es)	1979-11-16	Procedimiento para la preparacion de isoquinoleinas.
ATE132858T1 (de)	1996-01-15	4-cinnolinon-derivate, ihre herstellung und ihre verwendung als arzneimittel
AU7414691A (en)	1991-10-10	New 3-aminochroman derivatives, process for preparing these and pharmaceutical compositions containing them
ATE62908T1 (de)	1991-05-15	Neue derivate von 4,5-dihydro-oxazolen, verfahren zu ihrer herstellung und ihre verwendung.
SE8303913L (sv)	1984-01-09	Heterocykliska foreningar
ATE48413T1 (de)	1989-12-15	Aryloxy-n-(aminoalkyl)-1-pyrrolidin und piperidincarboxamide und carbothioamide die antiarrhythmische wirkung hervorrufen.
ATE341329T1 (de)	2006-10-15	Arzneimittel zur behandlung von neuropathien
IL115085A (en)	1999-06-20	Piperazine bicyclic carboxamide derivatives their preparation and pharmaceutical compositions containing them
ATE33134T1 (de)	1988-04-15	2-aminoethyl-pyridin oder pyrazin-derivate, ihre herstellung und diese enthaltende pharmazeutische zusammensetzungen.
IL61771A (en)	1984-10-31	4-amino-2,6-diaryl-tetrahydrothiopyrans,their preparation and pharmaceutical compositions containing them
DE3860117D1 (de)	1990-06-07	2,3-dihydro-3-phenyl-benzofuran-2-on-acetamidderivate, verfahren zu ihrer herstellung und diese enthaltende arzneimittel.
SE8206230L (sv)	1983-05-07	Nya cykliska iminderivat, sett for deras framstellning och farmaceutiska beredningar innehallande dem

Legal Events

Date	Code	Title	Description
1996-07-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties