ATE101612T1 - Serotonin-antagonisten, ihre herstellung und sie enthaltende arzneimittel. - Google Patents

Serotonin-antagonisten, ihre herstellung und sie enthaltende arzneimittel.

Info

Publication number: ATE101612T1
Authority: AT; Austria
Prior art keywords: radical; optionally substituted; phenyl; denotes; preparation
Prior art date: 1989-12-13

Application number

AT90403502T

Other languages

English (en)

Inventor

Marie-Therese Comte

Claude Gueremy

Jean-Luc Malleron

Jean-Francois Peyronnel

Alain Truchon

Original Assignee

Rhone Poulenc Sante

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-12-13

Filing date

1990-12-10

Publication date

1994-03-15

1989-12-13 Priority claimed from FR898916459A external-priority patent/FR2655652B1/fr

1990-12-10 Application filed by Rhone Poulenc Sante filed Critical Rhone Poulenc Sante

1994-03-15 Application granted granted Critical

1994-03-15 Publication of ATE101612T1 publication Critical patent/ATE101612T1/de

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D275/00—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
- C07D275/04—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings condensed with carbocyclic rings or ring systems
- C07D275/06—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings condensed with carbocyclic rings or ring systems with hetero atoms directly attached to the ring sulfur atom
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/01—Five-membered rings
- C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D227/00—Heterocyclic compounds containing rings having one nitrogen atom as the only ring hetero atom, according to more than one of groups C07D203/00 - C07D225/00
- C07D227/02—Heterocyclic compounds containing rings having one nitrogen atom as the only ring hetero atom, according to more than one of groups C07D203/00 - C07D225/00 with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D227/06—Heterocyclic compounds containing rings having one nitrogen atom as the only ring hetero atom, according to more than one of groups C07D203/00 - C07D225/00 with only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D227/08—Oxygen atoms
- C07D227/087—One doubly-bound oxygen atom in position 2, e.g. lactams
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D279/02—1,2-Thiazines; Hydrogenated 1,2-thiazines
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/15—Six-membered rings
- C07D285/16—Thiadiazines; Hydrogenated thiadiazines
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/06—Peri-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/06—Peri-condensed systems

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Public Health (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Indole Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Thiazole And Isothizaole Compounds (AREA)
Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)

AT90403502T 1989-12-13 1990-12-10 Serotonin-antagonisten, ihre herstellung und sie enthaltende arzneimittel. ATE101612T1 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
FR898916459A FR2655652B1 (fr)	1989-12-13	1989-12-13	Antagonistes de la serotonine, leur preparation et les medicaments les contenant.
FR9006943A FR2662696A2 (fr)	1989-12-13	1990-06-05	Antagonistes de la serotonine, leur preparation et medicaments les contenant.
EP90403502A EP0433149B1 (de)	1989-12-13	1990-12-10	Serotonin-Antagonisten, ihre Herstellung und sie enthaltende Arzneimittel

Publications (1)

Publication Number	Publication Date
ATE101612T1 true ATE101612T1 (de)	1994-03-15

Family

ID=26227724

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT90403502T ATE101612T1 (de)	1989-12-13	1990-12-10	Serotonin-antagonisten, ihre herstellung und sie enthaltende arzneimittel.

Country Status (18)

Country	Link
US (1)	US5130313A (de)
EP (1)	EP0433149B1 (de)
JP (1)	JPH03255063A (de)
KR (1)	KR910011816A (de)
AT (1)	ATE101612T1 (de)
AU (1)	AU643241B2 (de)
CA (1)	CA2032104A1 (de)
DE (1)	DE69006699T2 (de)
DK (1)	DK0433149T3 (de)
ES (1)	ES2062465T3 (de)
FI (1)	FI906108L (de)
FR (1)	FR2662696A2 (de)
HU (1)	HU209301B (de)
IE (1)	IE904487A1 (de)
IL (1)	IL96617A0 (de)
NO (1)	NO905368L (de)
NZ (1)	NZ236436A (de)
PT (1)	PT96197A (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5057513A (en) *	1989-05-25	1991-10-15	Fujisawa Pharmaceutical Co., Ltd.	Spiro-thiazepine derivatives useful as paf antagonists
JPH0794439B2 (ja) *	1990-05-31	1995-10-11	フアイザー・インコーポレイテツド	置換ピペリジンの製造法
FR2675802B1 (fr) *	1991-04-26	1993-12-24	Rhone Poulenc Rorer Sa	Antiserotonines, leur preparation et les medicaments les contenant.
NZ243065A (en) *	1991-06-13	1995-07-26	Lundbeck & Co As H	Piperidine derivatives and pharmaceutical compositions
DE4120322A1 (de) *	1991-06-20	1992-12-24	Bayer Ag	Aminomethyl-substituierte 2,3-dihydropyrano(2,3-b)pyridine, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln
JP2776984B2 (ja) *	1992-09-14	1998-07-16	山之内製薬株式会社	新規な縮合チアゾール誘導体，その製造法及びその医薬組成物
US6001827A (en)	1993-12-24	1999-12-14	Suntory Limited	Benzothiazine derivative
CA2156849A1 (en) *	1993-12-24	1995-07-06	Akira Mizuno	Benzothiazine derivative
US5874429A (en) *	1993-12-24	1999-02-23	Suntory Limited	Benzothiazine derivative
JPH0912562A (ja) *	1995-06-22	1997-01-14	Suntory Ltd	置換ベンゾチアジン誘導体
US5728835A (en) *	1993-12-27	1998-03-17	Toa Eiyo, Ltd.	Substituted cyclic amine compound, production process thereof and pharmaceutical composition for circulatory organ use containing the same
GB9416571D0 (en) *	1994-08-16	1994-10-12	Battelle Memorial Institute	Novel alkylamino derivatives as sigma 2 selective ligands
JPH0967367A (ja) *	1995-06-23	1997-03-11	Suntory Ltd	チオピラン誘導体
ATE296801T1 (de)	1996-06-28	2005-06-15	Meiji Seika Kaisha	Tetrahydrobezindol derivate
PT956287E (pt) *	1996-12-23	2003-11-28	Aventis Pharma Inc	Derivados de 3-aril-2-(1-substituido-4-piperidinil)-1(1-di)oxo-3h-benzo¬disotiazol sua preparacao e sua utilizacao como moduladores da funcao neurotransmissora
GB9700895D0 (en) *	1997-01-17	1997-03-05	Lilly Co Eli	Pharmaceutical compounds
WO1999010346A1 (en) *	1997-08-22	1999-03-04	Eli Lilly And Company Limited	Benzothiadiazinyl-indole derivatives and their use as serotonin receptor ligands
DE19746612A1 (de) *	1997-10-22	1999-04-29	Basf Ag	2-Substituierte 1,2-Benzisothiazol-Derivate, ihre Herstellung und Verwendung
US6960579B1 (en) *	1998-05-19	2005-11-01	Alcon Manufacturing, Ltd.	Serotonergic 5HT7 receptor compounds for treating ocular and CNS disorders
US6265395B1 (en) *	1998-06-25	2001-07-24	Merck & Co., Inc.	Carbapenem antibacterial compounds, compositions containing such compounds and methods of treatment
GB9903784D0 (en) *	1999-02-18	1999-04-14	Lilly Co Eli	Pharmaceutical compounds

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3303189A (en) *	1965-03-11	1967-02-07	Smith Kline French Lab	2, 1-benzothiazine-2, 2-dioxides
US4110449A (en) *	1977-05-23	1978-08-29	E. R. Squibb & Sons, Inc.	2-substituted benzisothiazol-3-ones
FR2459235A1 (fr) *	1979-06-14	1981-01-09	Sanofi Sa	Nouveaux derives de sulfonyl-aniline, leur procede de preparation et leur application therapeutique
JP2556722B2 (ja) *	1988-02-18	1996-11-20	興和株式会社	新規なスルホンアミド化合物
FR2628425B1 (fr) *	1988-03-08	1992-04-03	Rhone Poulenc Sante	Derives d'isoindolinone, leurs procedes de preparation et les medicaments les contenant
IL90858A (en) *	1988-07-07	1994-08-26	Rhone Poulenc Sante	Derivatives of (AZA) naphthalensultam, their preparation and compositions containing them
EP0429341A3 (en) *	1989-11-20	1991-11-13	Rhone-Poulenc Sante	Heterocyclic derivatives, their preparation and pharmaceuticals containing them

1990
- 1990-06-05 FR FR9006943A patent/FR2662696A2/fr active Pending
- 1990-12-10 ES ES90403502T patent/ES2062465T3/es not_active Expired - Lifetime
- 1990-12-10 IL IL96617A patent/IL96617A0/xx unknown
- 1990-12-10 DE DE69006699T patent/DE69006699T2/de not_active Expired - Fee Related
- 1990-12-10 DK DK90403502.9T patent/DK0433149T3/da active
- 1990-12-10 EP EP90403502A patent/EP0433149B1/de not_active Expired - Lifetime
- 1990-12-10 AT AT90403502T patent/ATE101612T1/de not_active IP Right Cessation
- 1990-12-12 HU HU908242A patent/HU209301B/hu not_active IP Right Cessation
- 1990-12-12 NO NO90905368A patent/NO905368L/no unknown
- 1990-12-12 IE IE448790A patent/IE904487A1/en unknown
- 1990-12-12 AU AU67981/90A patent/AU643241B2/en not_active Expired - Fee Related
- 1990-12-12 CA CA002032104A patent/CA2032104A1/fr not_active Abandoned
- 1990-12-12 FI FI906108A patent/FI906108L/fi not_active Application Discontinuation
- 1990-12-12 KR KR1019900020402A patent/KR910011816A/ko not_active Withdrawn
- 1990-12-12 NZ NZ236436A patent/NZ236436A/en unknown
- 1990-12-13 PT PT96197A patent/PT96197A/pt not_active Application Discontinuation
- 1990-12-13 JP JP2410112A patent/JPH03255063A/ja active Pending
- 1990-12-13 US US07/627,101 patent/US5130313A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
PT96197A (pt)	1991-09-30
IE904487A1 (en)	1991-06-19
JPH03255063A (ja)	1991-11-13
EP0433149A2 (de)	1991-06-19
FI906108A7 (fi)	1991-06-14
DK0433149T3 (da)	1994-03-14
AU6798190A (en)	1991-06-20
FI906108L (fi)	1991-06-14
IL96617A0 (en)	1991-09-16
NZ236436A (en)	1993-03-26
HU209301B (en)	1994-04-28
EP0433149B1 (de)	1994-02-16
CA2032104A1 (fr)	1991-06-14
HU908242D0 (en)	1991-06-28
FI906108A0 (fi)	1990-12-12
NO905368L (no)	1991-06-14
EP0433149A3 (en)	1992-03-18
AU643241B2 (en)	1993-11-11
US5130313A (en)	1992-07-14
DE69006699D1 (de)	1994-03-24
HUT56566A (en)	1991-09-30
FR2662696A2 (fr)	1991-12-06
KR910011816A (ko)	1991-08-07
ES2062465T3 (es)	1994-12-16
DE69006699T2 (de)	1994-06-09
NO905368D0 (no)	1990-12-12

Legal Events

Date	Code	Title	Description
1994-08-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
DE69006699D1 (de)	1994-03-24	Serotonin-Antagonisten, ihre Herstellung und sie enthaltende Arzneimittel.
DK0646115T3 (da)	2003-04-22	Heterocykliske/cykliske aminderivater
SE8303208L (sv)	1983-12-08	Heterocykliska foreningar
ES2111639T3 (es)	1998-03-16	Derivados de 3-aminopiperidina y heterociclos relacionados que contienen nitrogeno.
NO930505L (no)	1993-08-16	Nye azaindoler, fremgangsmaate for deres fremstilling og farmasoeytiske preparater derav
ATE92485T1 (de)	1993-08-15	3-(4-piperidin)-5-(2-sulphonylaminoethyl)-indol derivate.
ATE206122T1 (de)	2001-10-15	Verbindungen, die als antiproliferative mittel und als garft inhibitoren verwendbar sind
DE69607650D1 (de)	2000-05-11	2,3,5-trimethyl-hydroxyanilid-derivative, ihre herstellung und ihre theraoeutische verwendung
ATE170530T1 (de)	1998-09-15	Thiazolidinderivate, ihre herstellung und medikamente, die sie enthalten
IE892189L (en)	1990-01-07	Derivatives of (aza) naphthalenesultam, their preparation¹and compositions containing them
MA21719A1 (fr)	1990-10-01	Procede de preparation de piperidines et de composes les contenant .
ATE140450T1 (de)	1996-08-15	Neue n-benzoylprolin-derivate, verfahren zur herstellung und diese enthaltende arzneimittel
HUP0000729A2 (hu)	2001-04-28	Új amidszármazékok és ezeket tartalmazó gyógyszerkészítmények
DK0450420T3 (da)	1995-02-20	Heterocyclisk substituerede dihydropyridiner, fremgangsmåde til deres fremstilling og deres anvendelse i lægemidler
NO159852C (no)	1989-02-15	Analogifremgangsm te for fremstilling av terapeutisk aktive derivater av piperidindion.
DE50003989D1 (de)	2003-11-13	Benzophenone und ihre verwendung als photoinitiatoren
DE59206593D1 (de)	1996-07-25	Verwendung von 2-Iminothiazolidin-4-onderivaten als neuartige Arzneimittelwirkstoffe
DE69100897D1 (de)	1994-02-10	N-phenyl-n-alkoxycarbonylalkyl-glycinamide, ihre herstellung und sie enthaltende medikamente.
ATE92058T1 (de)	1993-08-15	Pyrimidin-derivate, 2-(4-(alpha-heteroaryl-alphaaryl-(alpha-alkyl)-methoxy)-butyl)-1-piperaziny > mit serotoninergischer wirkung.
ATE79752T1 (de)	1992-09-15	Verwendung von chromanderivaten zur herstellung eines medikamentes zur behandlung von depressiven zustaenden.
ATE150024T1 (de)	1997-03-15	1,2,4-thiadiazino(3,4-b>benzothiazol-derivate, ihre herstellung und sie enthaltende arzneimittel
ATE132858T1 (de)	1996-01-15	4-cinnolinon-derivate, ihre herstellung und ihre verwendung als arzneimittel
DE69827706D1 (de)	2004-12-30	5-(Heteroaryl)alkyl)-3-oxo-pyrido(1,2-a)benzimidazol-4-carboxamid (PBI) Derivate zur Behandlung von Störungen des zentralen Nervensystems
NZ240298A (en)	1993-02-25	4-(4- and/or 6-(trifluoromethyl)pyrid-2-)piperazin-1-ylalkyl substituted lactam derivatives
ATE117896T1 (de)	1995-02-15	Arzneimittel welche substituierte 2-cyclohexen- 1yl-amin-derivate enthalten und ihre verwendung zur bekämpfung von krankheiten.