ATE133671T1 - Hexitolderivate - Google Patents

Hexitolderivate

Info

Publication number: ATE133671T1
Authority: AT; Austria
Prior art keywords: represents hydrogen; lower alkyl; chem; independently represents; integer
Prior art date: 1989-04-17

Application number

AT90107245T

Other languages

English (en)

Inventor

Fumio Suzuki

Hiroaki Hayashi

Shimotogari

Takeshi Kuroda

Kazuhiro Kubo

Junichi Ikeda

Original Assignee

Kyowa Hakko Kogyo Kk

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-04-17

Filing date

1990-04-17

Publication date

1996-02-15

1990-04-17 Application filed by Kyowa Hakko Kogyo Kk filed Critical Kyowa Hakko Kogyo Kk

1996-02-15 Application granted granted Critical

1996-02-15 Publication of ATE133671T1 publication Critical patent/ATE133671T1/de

Links

FBPFZTCFMRRESA-UHFFFAOYSA-N hexane-1,2,3,4,5,6-hexol Chemical class OCC(O)C(O)C(O)C(O)CO FBPFZTCFMRRESA-UHFFFAOYSA-N 0.000 title abstract 2
229910052739 hydrogen Inorganic materials 0.000 abstract 6
239000001257 hydrogen Substances 0.000 abstract 6
125000000217 alkyl group Chemical group 0.000 abstract 5
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 4
125000004423 acyloxy group Chemical group 0.000 abstract 2
150000002431 hydrogen Chemical class 0.000 abstract 2
125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 2
229910052760 oxygen Inorganic materials 0.000 abstract 2
206010002383 Angina Pectoris Diseases 0.000 abstract 1
125000005236 alkanoylamino group Chemical group 0.000 abstract 1
125000003282 alkyl amino group Chemical group 0.000 abstract 1
125000003435 aroyl group Chemical group 0.000 abstract 1
125000003118 aryl group Chemical group 0.000 abstract 1
QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
125000001589 carboacyl group Chemical group 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
150000002367 halogens Chemical class 0.000 abstract 1
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
208000010125 myocardial infarction Diseases 0.000 abstract 1
150000002825 nitriles Chemical class 0.000 abstract 1
239000001301 oxygen Substances 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
229910052717 sulfur Inorganic materials 0.000 abstract 1
125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
230000000304 vasodilatating effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Vascular Medicine (AREA)
Urology & Nephrology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

AT90107245T 1989-04-17 1990-04-17 Hexitolderivate ATE133671T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP9703289		1989-04-17
JP29312589		1989-11-10

Publications (1)

Publication Number	Publication Date
ATE133671T1 true ATE133671T1 (de)	1996-02-15

Family

ID=26438216

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT90107245T ATE133671T1 (de)	1989-04-17	1990-04-17	Hexitolderivate

Country Status (9)

Country	Link
US (1)	US5053408A (de)
EP (1)	EP0393574B1 (de)
JP (1)	JP2954647B2 (de)
AT (1)	ATE133671T1 (de)
CA (1)	CA2014520C (de)
DE (1)	DE69025084T2 (de)
DK (1)	DK0393574T3 (de)
ES (1)	ES2085295T3 (de)
GR (1)	GR3019515T3 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5120737A (en) *	1990-09-28	1992-06-09	Kyowa Hakko Kogyo Co., Ltd.	Hexitol derivatives
US5674894A (en) *	1995-05-15	1997-10-07	G.D. Searle & Co.	Amidine derivatives useful as platelet aggregation inhibitors and vasodilators
ES2142773B1 (es)	1998-10-07	2001-01-01	Lacer Sa	Derivados de mononitrato de isosorbida y su empleo como agentes vasodilatadores con tolerancia desminuida.
US6906072B1 (en) *	2000-01-20	2005-06-14	Eisai Co., Ltd.	Piperazine compound and pharmaceutical composition containing the compound
US7465738B2 (en)	2003-06-16	2008-12-16	Vertex Pharmaceuticals Incorporated	Compounds useful as promoters of SMN2
EP2221295B1 (de) *	2007-12-17	2014-01-01	National University Corporation Yamaguchi University	Geliermittel mit fluoroalkylderivat

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3028340C2 (de) *	1980-07-25	1987-02-05	Dr. Willmar Schwabe GmbH & Co, 7500 Karlsruhe	Amino-desoxy-1.4;3.6-dianhydro-hexit-nitrate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende pharmazeutische Zubereitungen
DE3028272A1 (de) *	1980-07-25	1982-02-25	Fa. Dr. Willmar Schwabe, 7500 Karlsruhe	Durch purinbasen substituierte alkylamino-desoxy-1.4;3.6-dianhydro-hexit-nitrate, verfahren zu ihrer herstellung und pharmazeutische zubereitung
DE3028273A1 (de) *	1980-07-25	1982-02-25	Fa. Dr. Willmar Schwabe, 7500 Karlsruhe	Durch purinbasen substituierte 1.4;3.6-dianhydro-hexit-nitrate
DE3028288A1 (de) *	1980-07-25	1982-02-25	Fa. Dr. Willmar Schwabe, 7500 Karlsruhe	Gegebenenfalls n-substituierte aminodesoxy-1.4;3.6-dianhydro-hexit-derivate, verfahren zu ihrer herstellung und deren verwendung

1990
- 1990-04-12 CA CA002014520A patent/CA2014520C/en not_active Expired - Fee Related
- 1990-04-13 US US07/508,701 patent/US5053408A/en not_active Expired - Fee Related
- 1990-04-16 JP JP2100005A patent/JP2954647B2/ja not_active Expired - Lifetime
- 1990-04-17 ES ES90107245T patent/ES2085295T3/es not_active Expired - Lifetime
- 1990-04-17 DE DE69025084T patent/DE69025084T2/de not_active Expired - Fee Related
- 1990-04-17 DK DK90107245.4T patent/DK0393574T3/da active
- 1990-04-17 EP EP90107245A patent/EP0393574B1/de not_active Expired - Lifetime
- 1990-04-17 AT AT90107245T patent/ATE133671T1/de not_active IP Right Cessation
1996
- 1996-04-02 GR GR960400903T patent/GR3019515T3/el unknown

Also Published As

Publication number	Publication date
EP0393574B1 (de)	1996-01-31
DE69025084T2 (de)	1996-06-13
EP0393574A2 (de)	1990-10-24
JPH03218381A (ja)	1991-09-25
CA2014520A1 (en)	1990-10-17
US5053408A (en)	1991-10-01
ES2085295T3 (es)	1996-06-01
JP2954647B2 (ja)	1999-09-27
EP0393574A3 (de)	1991-08-21
GR3019515T3 (en)	1996-07-31
DK0393574T3 (da)	1996-02-19
CA2014520C (en)	1996-07-16
DE69025084D1 (de)	1996-03-14

Legal Events

Date	Code	Title	Description
1996-08-15	UEP	Publication of translation of european patent specification
2003-01-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
ATE107636T1 (de)	1994-07-15	Substituierte phenyl-2-propensäure derivate und ihre verwendung als fungizide.
PT84766B (pt)	1989-12-29	Processo para a preparacao de poliocicloalquil-amino (ou oxi)-benzenos substituidos com heterociclico, uteis como agentes antidepressivos
UA37178C2 (uk)	2001-05-15	Терапевтичні гетероциклічні сполуки, спосіб їх одержання, спосіб профілактики та лікування, лікарський засіб та спосіб його одержання
PT87063A (pt)	1988-04-01	Heterocyclic compounds and their preparation and use
FI900461A0 (fi)	1990-01-30	Imidazopyridaziner, deras framstaellning och anvaendning.
DK0393574T3 (da)	1996-02-19	Hexitolderivater
ATE45877T1 (de)	1989-09-15	Naphthalenische anti-sporiasis-wirkstoffe.
ATE125540T1 (de)	1995-08-15	Imidazochinolon-derivate.
DE68926810D1 (de)	1996-08-14	Benzoxazepinon-Verfahren
DK35885A (da)	1985-07-28	Naphthalenderivater
ATE77362T1 (de)	1992-07-15	Naphthalenische antipsoriasismittel und ihr herstellungsverfahren.
TH2663A (th)	1985-08-02	สารประกอบเฮเทอโรไซคลิค