ATE135212T1 - Arzneimittel für die verhütung und behandlung von krankheiten der kreislauforgane enthaltend spiro- 3-heteroazolidin-verbindungen - Google Patents

Arzneimittel für die verhütung und behandlung von krankheiten der kreislauforgane enthaltend spiro- 3-heteroazolidin-verbindungen

Info

Publication number: ATE135212T1
Authority: AT; Austria
Prior art keywords: group; atom; oxygen; heteroazolidine; circulative
Prior art date: 1990-11-07

Application number

AT91310322T

Other languages

English (en)

Inventor

Masayasu Sanwa Kagaku K Kurono

Higashi-Ku Cho

Kenji Sanwa Kagaku Kenky Miura

Higashi-Ku

Yasuaki Sanwa Kagaku Ken Kondo

Toshinao Sanwa Kagaku Ken Usui

Motohide Sanwa Kagaku Hayashi

Tunemasa Sanwa Kagaku K Suzuki

Noboru Sanwa Kagaku Ken Tomiya

Shigeyoshi Sanwa Kaga Nakamura

Yukiya Sanwa Kagaku Ken Tanaka

Kiichi Sanwa Kagaku Kenk Sawai

Original Assignee

Sanwa Kagaku Kenkyusho Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-11-07

Filing date

1991-11-07

Publication date

1996-03-15

1991-11-07 Application filed by Sanwa Kagaku Kenkyusho Co filed Critical Sanwa Kagaku Kenkyusho Co

1996-03-15 Application granted granted Critical

1996-03-15 Publication of ATE135212T1 publication Critical patent/ATE135212T1/de

Links

150000001875 compounds Chemical class 0.000 title abstract 2
201000010099 disease Diseases 0.000 title abstract 2
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title abstract 2
210000000056 organ Anatomy 0.000 title abstract 2
229940126601 medicinal product Drugs 0.000 title 1
230000002265 prevention Effects 0.000 title 1
229910052757 nitrogen Inorganic materials 0.000 abstract 3
229910052717 sulfur Inorganic materials 0.000 abstract 3
125000004434 sulfur atom Chemical group 0.000 abstract 3
IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 2
MYMOFIZGZYHOMD-UHFFFAOYSA-N Dioxygen Chemical compound O=O MYMOFIZGZYHOMD-UHFFFAOYSA-N 0.000 abstract 2
125000000217 alkyl group Chemical group 0.000 abstract 2
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
125000004433 nitrogen atom Chemical group N* 0.000 abstract 2
229910052760 oxygen Inorganic materials 0.000 abstract 2
239000001301 oxygen Substances 0.000 abstract 2
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
125000003545 alkoxy group Chemical group 0.000 abstract 1
125000004414 alkyl thio group Chemical group 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
125000005843 halogen group Chemical group 0.000 abstract 1
125000000623 heterocyclic group Chemical group 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
125000001841 imino group Chemical group [H]N=* 0.000 abstract 1
239000004615 ingredient Substances 0.000 abstract 1
125000004430 oxygen atom Chemical group O* 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
239000012453 solvate Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Epidemiology (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Hospice & Palliative Care (AREA)
Diabetes (AREA)
Hematology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

AT91310322T 1990-11-07 1991-11-07 Arzneimittel für die verhütung und behandlung von krankheiten der kreislauforgane enthaltend spiro- 3-heteroazolidin-verbindungen ATE135212T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP2301518A JP2997894B2 (ja)	1990-11-07	1990-11-07	循環器系疾患の予防及び治療剤

Publications (1)

Publication Number	Publication Date
ATE135212T1 true ATE135212T1 (de)	1996-03-15

Family

ID=17897897

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT91310322T ATE135212T1 (de)	1990-11-07	1991-11-07	Arzneimittel für die verhütung und behandlung von krankheiten der kreislauforgane enthaltend spiro- 3-heteroazolidin-verbindungen

Country Status (6)

Country	Link
EP (1)	EP0485219B1 (de)
JP (1)	JP2997894B2 (de)
AT (1)	ATE135212T1 (de)
DE (1)	DE69117879T2 (de)
DK (1)	DK0485219T3 (de)
ES (1)	ES2084120T3 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0719556B1 (de) *	1994-12-28	2000-10-25	Sanwa Kagaku Kenkyusho Co., Ltd.	Verwendung von (2S,4S)-6-fluoro-2',5'-dioxospiro[chroman-4,4'-imidazoline]-2-carboxamid zur Behandlung von Keratopathie
US7094800B2 (en)	2003-07-25	2006-08-22	Sanofi-Aventis Deutschland Gmbh	Cyanopyrrolidides, process for their preparation and their use as medicaments
PE20050249A1 (es) *	2003-07-25	2005-06-01	Aventis Pharma Gmbh	Nuevas cianopirrolididas y procedimiento para su preparacion como medicamentos
ES2393271T3 (es)	2005-12-16	2012-12-19	Sanwa Kagaku Kenkyusho Co., Ltd	Agente para la prevención y tratamiento de la insuficiencia renal aguda
WO2007097301A1 (ja) *	2006-02-20	2007-08-30	Sanwa Kagaku Kenkyusho Co., Ltd.	脳卒中における脳虚血又は脳虚血再灌流障害の予防又は治療剤
EP2594267A1 (de)	2007-01-31	2013-05-22	Sanwa Kagaku Kenkyusho Co., Ltd	Wirkstoff zum Schutz der Retinanerven oder der Sehnerven
AU2011206104A1 (en)	2010-01-14	2012-07-12	Nagoya City University	Pharmaceutical for preventing or treating disorders accompanied by ocular angiogenesis and/or elevated ocular vascular permeability
AU2011246232A1 (en) *	2010-04-28	2012-11-01	Sanwa Kagaku Kenkyusho Co., Ltd.	Prophylactic or therapeutic medication for inner ear disorders

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS61200991A (ja) *	1985-03-04	1986-09-05	Sanwa Kagaku Kenkyusho:Kk	スピロ―３―ヘテロアゾリジン化合物、その製法及びそれを有効成分とする糖尿病合併症の予防及び治療剤
US5164391A (en) *	1989-09-20	1992-11-17	Sanwa Kagaku Kenkyusho Co., Ltd.	Hydantoin derivatives for treating complications of diabetes and circulatory diseases

1990
- 1990-11-07 JP JP2301518A patent/JP2997894B2/ja not_active Expired - Lifetime
1991
- 1991-11-07 DK DK91310322.2T patent/DK0485219T3/da active
- 1991-11-07 ES ES91310322T patent/ES2084120T3/es not_active Expired - Lifetime
- 1991-11-07 EP EP91310322A patent/EP0485219B1/de not_active Expired - Lifetime
- 1991-11-07 AT AT91310322T patent/ATE135212T1/de not_active IP Right Cessation
- 1991-11-07 DE DE69117879T patent/DE69117879T2/de not_active Expired - Fee Related

Also Published As

Publication number	Publication date
EP0485219B1 (de)	1996-03-13
DK0485219T3 (da)	1996-07-22
JPH04173791A (ja)	1992-06-22
JP2997894B2 (ja)	2000-01-11
DE69117879D1 (de)	1996-04-18
ES2084120T3 (es)	1996-05-01
EP0485219A2 (de)	1992-05-13
DE69117879T2 (de)	1996-08-08
EP0485219A3 (en)	1992-10-14

Legal Events

Date	Code	Title	Description
1996-08-15	UEP	Publication of translation of european patent specification
1998-02-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
MX9306831A (es)	1995-01-31	Nuevos compuestos heterociclicos.
ATE79376T1 (de)	1992-08-15	Dithioacetal-verbindungen, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzungen.
DK490288A (da)	1989-03-05	Substituerede thiazolidindionderivater
NO882036D0 (no)	1988-05-10	Fremgangsmaate for fremstilling av terapeutisk aktive heterocykliske ketoner.
BG95344A (bg)	1993-12-24	Фунгицидни оксазолидинони
DE69131359D1 (de)	1999-07-29	Kondensierte Thiazolverbindungen, ihre Darstellung und ihre Anwendung
ATE135212T1 (de)	1996-03-15	Arzneimittel für die verhütung und behandlung von krankheiten der kreislauforgane enthaltend spiro- 3-heteroazolidin-verbindungen
NO304486B1 (no)	1998-12-28	Oksazolidonderivater og anvendelser derav, og midler og medisinske preparater omfattende slike oksazolidonderivater
KR937000438A (ko)	1993-03-15	3-인돌릴 티오아세테이트 유도체
AR043271A1 (es)	2005-07-27	Compuestos de dihidropironas con heterociclos unidos y su uso en composicines farmaceuticas que poseen actividad inhibidora de hiv proteasa
DE60009517D1 (de)	2004-05-06	A-500359-derivate
JPS5716841A (en)	1982-01-28	Novel compound,manufacture,bactericidal composition and use
ATE63541T1 (de)	1991-06-15	N-phenylethylaminoalkyl-benzamide als antiarrhythmische mittel.
ATE86117T1 (de)	1993-03-15	Zusammensetzung gegen leberkrankheiten.
ATE305783T1 (de)	2005-10-15	Verwendung von diaminotrifluoromethylpyridinderivaten für die prevention und behandlung von lebererkrankungen
IL93949A0 (en)	1990-12-23	Thioformamide derivatives and pharmaceutical compositions containing them
ATE275560T1 (de)	2004-09-15	Bemzimidazolverbindungen und medikamente die diese enthalten
ATE81466T1 (de)	1992-10-15	Verwendung von 2-oxo-imidazolidin-derivaten zur prophylaxe und zur behandlung von herzinsuffizienz.
ATE132748T1 (de)	1996-01-15	Verwendung eines dihydropyridins zur verbesserung der blutzirkulation des inneren ohres
DE3782229D1 (de)	1992-11-19	Verwendung von 2-oxo-imidazolidin-derivaten zur behandlung von nierenkrankheiten.
DE68909961D1 (de)	1993-11-25	2-Aminoacetamid Derivate.
ATE44741T1 (de)	1989-08-15	2-(n-substituierte guanidino)-4heteroarylthiazole als mittel gegen geschwuere.