ATE275560T1 - Bemzimidazolverbindungen und medikamente die diese enthalten - Google Patents
Bemzimidazolverbindungen und medikamente die diese enthaltenInfo
- Publication number
- ATE275560T1 ATE275560T1 AT00940847T AT00940847T ATE275560T1 AT E275560 T1 ATE275560 T1 AT E275560T1 AT 00940847 T AT00940847 T AT 00940847T AT 00940847 T AT00940847 T AT 00940847T AT E275560 T1 ATE275560 T1 AT E275560T1
- Authority
- AT
- Austria
- Prior art keywords
- group
- represented
- hydrogen atom
- bemzimidazole
- compounds
- Prior art date
Links
- 239000003814 drug Substances 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 title 1
- 229940079593 drug Drugs 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000000524 functional group Chemical group 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 206010003210 Arteriosclerosis Diseases 0.000 abstract 1
- IAYPIBMASNFSPL-UHFFFAOYSA-N Ethylene oxide Chemical group C1CO1 IAYPIBMASNFSPL-UHFFFAOYSA-N 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 208000011775 arteriosclerosis disease Diseases 0.000 abstract 1
- -1 benzimidazole compound Chemical class 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 125000005647 linker group Chemical group 0.000 abstract 1
- 210000002540 macrophage Anatomy 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 230000003449 preventive effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP18556899 | 1999-06-30 | ||
| PCT/JP2000/004204 WO2001000613A1 (en) | 1999-06-30 | 2000-06-27 | Benzimidazole compounds and drugs containing the same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE275560T1 true ATE275560T1 (de) | 2004-09-15 |
Family
ID=16173093
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00940847T ATE275560T1 (de) | 1999-06-30 | 2000-06-27 | Bemzimidazolverbindungen und medikamente die diese enthalten |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US6593323B1 (de) |
| EP (1) | EP1201664B1 (de) |
| JP (1) | JP4560259B2 (de) |
| KR (1) | KR20020025091A (de) |
| AT (1) | ATE275560T1 (de) |
| AU (1) | AU776803B2 (de) |
| CA (1) | CA2377230C (de) |
| DE (1) | DE60013607T2 (de) |
| WO (1) | WO2001000613A1 (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE257826T1 (de) * | 1999-06-28 | 2004-01-15 | Fuji Photo Film Co Ltd | Benzimidazolderivate und sie enthaltende medikamente |
| EP1201664B1 (de) | 1999-06-30 | 2004-09-08 | Fuji Photo Film Co., Ltd. | Bemzimidazolverbindungen und medikamente die diese enthalten |
| JP4624616B2 (ja) | 1999-07-07 | 2011-02-02 | 富士フイルム株式会社 | ベンズイミダゾール化合物 |
| WO2011097491A1 (en) * | 2010-02-04 | 2011-08-11 | Glaxosmithkline Llc | Benzimidazole antiviral agents |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AT371816B (de) * | 1979-10-08 | 1983-08-10 | Henkel Kgaa | Verfahren zur herstellung von neuen isocyanurs[urederivaten |
| IT1226100B (it) | 1988-07-07 | 1990-12-10 | Dompe Farmaceutici Spa | Derivati benzimidazolici farmacologicamente attivi. |
| US5387600A (en) | 1992-07-30 | 1995-02-07 | Fuji Photo Film Co., Ltd. | Treating arteriosclerosis using benzimidazole compositions |
| US6376666B1 (en) * | 1994-06-10 | 2002-04-23 | Nauchno-Issledovatelsky Institut Farmakologii Rossiiskoi Akademii Meditsinskikh Nauk | 2-mercaptobenzimidazole derivatives possessing pharmacological activity |
| US5998456A (en) * | 1995-07-17 | 1999-12-07 | Fuji Photo Film Co., Ltd. | Benzimidazole compounds containing 1,2,4-triazole ring, and compositions and methods of use containing the same |
| WO1998054153A1 (en) | 1997-05-26 | 1998-12-03 | Kowa Company, Ltd. | Novel cyclic diamine compounds and medicine containing the same |
| EP0979823B1 (de) | 1997-11-14 | 2006-03-29 | Kowa Company Ltd. | Neue amidverbindungen und medikamente die diese enthalten |
| EP1201664B1 (de) | 1999-06-30 | 2004-09-08 | Fuji Photo Film Co., Ltd. | Bemzimidazolverbindungen und medikamente die diese enthalten |
-
2000
- 2000-06-27 EP EP00940847A patent/EP1201664B1/de not_active Expired - Lifetime
- 2000-06-27 US US10/019,562 patent/US6593323B1/en not_active Expired - Fee Related
- 2000-06-27 DE DE60013607T patent/DE60013607T2/de not_active Expired - Lifetime
- 2000-06-27 CA CA002377230A patent/CA2377230C/en not_active Expired - Fee Related
- 2000-06-27 WO PCT/JP2000/004204 patent/WO2001000613A1/ja not_active Ceased
- 2000-06-27 KR KR1020017016736A patent/KR20020025091A/ko not_active Ceased
- 2000-06-27 AU AU55697/00A patent/AU776803B2/en not_active Ceased
- 2000-06-27 AT AT00940847T patent/ATE275560T1/de not_active IP Right Cessation
- 2000-06-27 JP JP2001507022A patent/JP4560259B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JP4560259B2 (ja) | 2010-10-13 |
| WO2001000613A1 (en) | 2001-01-04 |
| AU776803B2 (en) | 2004-09-23 |
| DE60013607D1 (de) | 2004-10-14 |
| CA2377230A1 (en) | 2001-01-04 |
| EP1201664A1 (de) | 2002-05-02 |
| KR20020025091A (ko) | 2002-04-03 |
| CA2377230C (en) | 2009-06-02 |
| US6593323B1 (en) | 2003-07-15 |
| AU5569700A (en) | 2001-01-31 |
| DE60013607T2 (de) | 2005-09-29 |
| EP1201664A4 (de) | 2002-12-18 |
| EP1201664B1 (de) | 2004-09-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |