ATE135399T1 - Rekombinante dna-expressionsvektoren und dna- komponenten, die für eine acyltransferase- aktivität von aspergillus kodieren - Google Patents

Rekombinante dna-expressionsvektoren und dna- komponenten, die für eine acyltransferase- aktivität von aspergillus kodieren

Info

Publication number: ATE135399T1
Authority: AT; Austria
Prior art keywords: aspergillus; expression vectors; acyltransferase activity; recombinant dna; dna
Prior art date: 1989-09-27

Application number

AT90310448T

Other languages

English (en)

Inventor

James Robert Miller

Paul Luther Skatrud

Matthew Barry Tobin

Original Assignee

Lilly Co Eli

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-09-27

Filing date

1990-09-25

Publication date

1996-03-15

1990-09-25 Application filed by Lilly Co Eli filed Critical Lilly Co Eli

1996-03-15 Application granted granted Critical

1996-03-15 Publication of ATE135399T1 publication Critical patent/ATE135399T1/de

Links

102000057234 Acyl transferases Human genes 0.000 title abstract 2
108700016155 Acyl transferases Proteins 0.000 title abstract 2
241000228212 Aspergillus Species 0.000 title abstract 2
108020004414 DNA Proteins 0.000 title abstract 2
108020004511 Recombinant DNA Proteins 0.000 title abstract 2
239000013604 expression vector Substances 0.000 title abstract 2
MIFYHUACUWQUKT-UHFFFAOYSA-N Isopenicillin N Natural products OC(=O)C1C(C)(C)SC2C(NC(=O)CCCC(N)C(O)=O)C(=O)N21 MIFYHUACUWQUKT-UHFFFAOYSA-N 0.000 abstract 2
150000001875 compounds Chemical class 0.000 abstract 2
241000351920 Aspergillus nidulans Species 0.000 abstract 1
229930186147 Cephalosporin Natural products 0.000 abstract 1
241000588724 Escherichia coli Species 0.000 abstract 1
241000233866 Fungi Species 0.000 abstract 1
241000228143 Penicillium Species 0.000 abstract 1
229950008644 adicillin Drugs 0.000 abstract 1
229940124587 cephalosporin Drugs 0.000 abstract 1
150000001780 cephalosporins Chemical class 0.000 abstract 1
MIFYHUACUWQUKT-QSKNDCFUSA-N isopenicillin n Chemical compound OC(=O)[C@@H]1C(C)(C)S[C@H]2[C@H](NC(=O)CCC[C@H](N)C(O)=O)C(=O)N21 MIFYHUACUWQUKT-QSKNDCFUSA-N 0.000 abstract 1
MIFYHUACUWQUKT-GPUHXXMPSA-N penicillin N Chemical compound OC(=O)[C@H]1C(C)(C)S[C@@H]2[C@H](NC(=O)CCC[C@@H](N)C(O)=O)C(=O)N21 MIFYHUACUWQUKT-GPUHXXMPSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P35/00—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1025—Acyltransferases (2.3)
- C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P37/00—Preparation of compounds having a 4-thia-1-azabicyclo [3.2.0] heptane ring system, e.g. penicillin

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
Biochemistry (AREA)
General Engineering & Computer Science (AREA)
Microbiology (AREA)
Biotechnology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
Biomedical Technology (AREA)
Enzymes And Modification Thereof (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)

AT90310448T 1989-09-27 1990-09-25 Rekombinante dna-expressionsvektoren und dna- komponenten, die für eine acyltransferase- aktivität von aspergillus kodieren ATE135399T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US41340189A	1989-09-27	1989-09-27

Publications (1)

Publication Number	Publication Date
ATE135399T1 true ATE135399T1 (de)	1996-03-15

Family

ID=23637073

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT90310448T ATE135399T1 (de)	1989-09-27	1990-09-25	Rekombinante dna-expressionsvektoren und dna- komponenten, die für eine acyltransferase- aktivität von aspergillus kodieren

Country Status (9)

Country	Link
EP (1)	EP0422790B1 (de)
JP (1)	JPH03133384A (de)
AT (1)	ATE135399T1 (de)
CA (1)	CA2026262A1 (de)
DE (1)	DE69025845T2 (de)
DK (1)	DK0422790T3 (de)
ES (1)	ES2086374T3 (de)
GR (1)	GR3019852T3 (de)
IL (1)	IL95766A (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5318896A (en) *	1991-09-11	1994-06-07	Merck & Co., Inc.	Recombinant expandase bioprocess for preparing 7-aminodesacetoxy cephalosporanic acid (7-ADCA)
KR100227711B1 (ko) *	1991-10-15	1999-12-01	한스 발터 라벤	7-아미노세팔로스포란산 및 7-아미노데아세틸세팔로스포란산 제조를 위한 신규한 생물학적 공정
US5882883A (en) *	1994-09-28	1999-03-16	Novo Nordisk A/S	Process for the production of secondary metabolites
EP0914463A2 (de) *	1996-07-16	1999-05-12	Gist-Brocades B.V.	Verfahren zur herstellung von cephalosporinen durch anwendung von acremonium chrysogenum

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1989009821A1 (fr) *	1988-04-08	1989-10-19	Biochemie Gesellschaft M.B.H.	GENE ET PRODUIT DE GENE POUR PREPARER DES COMPOSES DE beta-LACTAME

1990
- 1990-09-24 IL IL9576690A patent/IL95766A/en not_active IP Right Cessation
- 1990-09-25 ES ES90310448T patent/ES2086374T3/es not_active Expired - Lifetime
- 1990-09-25 DK DK90310448.7T patent/DK0422790T3/da active
- 1990-09-25 DE DE69025845T patent/DE69025845T2/de not_active Expired - Fee Related
- 1990-09-25 AT AT90310448T patent/ATE135399T1/de not_active IP Right Cessation
- 1990-09-25 EP EP90310448A patent/EP0422790B1/de not_active Expired - Lifetime
- 1990-09-26 CA CA002026262A patent/CA2026262A1/en not_active Abandoned
- 1990-09-27 JP JP2260282A patent/JPH03133384A/ja active Pending
1996
- 1996-05-07 GR GR960401237T patent/GR3019852T3/el unknown

Also Published As

Publication number	Publication date
CA2026262A1 (en)	1991-03-28
DE69025845D1 (de)	1996-04-18
EP0422790A3 (en)	1991-08-21
IL95766A0 (en)	1991-06-30
IL95766A (en)	1996-12-05
EP0422790B1 (de)	1996-03-13
DK0422790T3 (da)	1996-05-06
EP0422790A2 (de)	1991-04-17
JPH03133384A (ja)	1991-06-06
DE69025845T2 (de)	1996-10-31
GR3019852T3 (en)	1996-08-31
ES2086374T3 (es)	1996-07-01

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Legal Events

Date	Code	Title	Description
1996-08-15	UEP	Publication of translation of european patent specification
2005-06-15	REN	Ceased due to non-payment of the annual fee