ATE135402T1 - Reinigung von erwinia-l-asparaginase - Google Patents

Reinigung von erwinia-l-asparaginase

Info

Publication number
ATE135402T1
ATE135402T1 AT91913903T AT91913903T ATE135402T1 AT E135402 T1 ATE135402 T1 AT E135402T1 AT 91913903 T AT91913903 T AT 91913903T AT 91913903 T AT91913903 T AT 91913903T AT E135402 T1 ATE135402 T1 AT E135402T1
Authority
AT
Austria
Prior art keywords
asparaginase
pct
purification
sec
cation exchange
Prior art date
Application number
AT91913903T
Other languages
English (en)
Inventor
Christopher Roderick Goward
Original Assignee
Health Lab Service Board
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Health Lab Service Board filed Critical Health Lab Service Board
Application granted granted Critical
Publication of ATE135402T1 publication Critical patent/ATE135402T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
    • C12N9/82—Asparaginase (3.5.1.1)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/814—Enzyme separation or purification
    • Y10S435/815—Enzyme separation or purification by sorption
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/847—Erwinia

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Detergent Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT91913903T 1990-08-02 1991-08-01 Reinigung von erwinia-l-asparaginase ATE135402T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB909017002A GB9017002D0 (en) 1990-08-02 1990-08-02 Improved method for the purification of erwina l-asparaginase

Publications (1)

Publication Number Publication Date
ATE135402T1 true ATE135402T1 (de) 1996-03-15

Family

ID=10680081

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91913903T ATE135402T1 (de) 1990-08-02 1991-08-01 Reinigung von erwinia-l-asparaginase

Country Status (10)

Country Link
US (1) US5310670A (de)
EP (1) EP0541633B1 (de)
JP (1) JPH05508546A (de)
AT (1) ATE135402T1 (de)
AU (1) AU647819B2 (de)
CA (1) CA2075289A1 (de)
DE (1) DE69117956T2 (de)
DK (1) DK0541633T3 (de)
GB (1) GB9017002D0 (de)
WO (1) WO1992002616A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE372059T1 (de) 2002-10-11 2007-09-15 Novozymes As Verfahren zur herstellung von wärmebehandelten produkten
BR0317298A (pt) * 2002-12-19 2005-11-08 Dsm Ip Assets Bv Processo para produção de alimentos
WO2006138181A2 (en) 2005-06-14 2006-12-28 Amgen Inc. Self-buffering protein formulations
AU2013204044B2 (en) * 2007-11-30 2017-08-31 Abbvie Biotechnology Ltd. Protein formulations and methods of making same
KR20210049186A (ko) * 2007-11-30 2021-05-04 애브비 바이오테크놀로지 리미티드 단백질 제형 및 이의 제조방법
US8883146B2 (en) 2007-11-30 2014-11-11 Abbvie Inc. Protein formulations and methods of making same
WO2011003633A1 (en) 2009-07-06 2011-01-13 Alize Pharma Ii Pegylated l-asparaginase
EP3463308B2 (de) 2016-06-01 2026-01-07 Servier IP UK Limited Formulierungen von polyalkylen-oxid-asparaginase und verfahren zur herstellung und verwendung davon
ES3064802T3 (en) 2016-10-21 2026-04-29 Amgen Inc Pharmaceutical formulations and methods of making the same
KR102727396B1 (ko) * 2017-06-21 2024-11-08 재즈 파마슈티칼즈 아일랜드 리미티드 변형된 l-아스파라기나아제
WO2019083793A1 (en) 2017-10-27 2019-05-02 Pfenex Inc. Method for production of recombinant erwinia asparaginase
US10662433B2 (en) 2017-10-27 2020-05-26 Pfenex Inc. Method for production of recombinant E. coli asparaginase
US20220313798A1 (en) 2021-03-30 2022-10-06 Jazz Pharmaceuticals Ireland Ltd. Dosing of recombinant l-asparaginase

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1767389A1 (de) * 1968-05-06 1971-09-02 Bayer Ag Verfahren zur Abtrennung von Pyrogenen aus Rohpraeparaten von L-Asparaginase
DE1916723C3 (de) * 1968-04-05 1973-07-05 Kyowa Hakko Kogyo Kk Verfahren zur Reinigung von L-Asparaginase
US3597323A (en) * 1968-06-07 1971-08-03 Wadley Res Inst & Blood Bank Method of purifying l-asparaginase
US3637462A (en) * 1969-04-21 1972-01-25 Wadley Res Inst & Blood Bank Purification of enzymes
SU436085A1 (ru) * 1972-08-07 1974-07-15 В. М. Денисов, В. И. Максимов , Г. А. Молодова Способ очистки l-аспарагиназы
US4729957A (en) * 1984-12-13 1988-03-08 The United States Of America As Represented By The Department Of Health And Human Services Process for manufacture of L-asparaginase from erwinia chrysanthemi
AU6773487A (en) * 1985-12-13 1987-06-30 United States of America, as represented by the Secretary, U.S. Department of Commerce, The Process for manufacture of l-asparaginase from erwinia carotovora

Also Published As

Publication number Publication date
DK0541633T3 (da) 1996-07-22
EP0541633A1 (de) 1993-05-19
GB9017002D0 (en) 1990-09-19
EP0541633B1 (de) 1996-03-13
AU8280591A (en) 1992-03-02
DE69117956T2 (de) 1996-07-25
AU647819B2 (en) 1994-03-31
WO1992002616A1 (en) 1992-02-20
CA2075289A1 (en) 1992-02-03
DE69117956D1 (de) 1996-04-18
US5310670A (en) 1994-05-10
JPH05508546A (ja) 1993-12-02

Similar Documents

Publication Publication Date Title
IE893159L (en) Method for the purification of proteins
DE69117956D1 (de) Reinigung von erwinia-l-asparaginase
EA199800159A1 (ru) Способ очистки вирусов с помощью хроматографии
ATE303434T1 (de) Effiziente reinigung von adenovirus
DK0620709T3 (da) Fremgangsmåde til isolering af lactoferrin og lactoperoxidase fra mælk og mælkeprodukter
NO177214C (no) Anordning ved en stol som omfatter understöttende og fjærende elementer som tillater ettergivende bevegelse av stolen i forhold til et underlag
ES8506902A1 (es) Un procedimiento para la purificacion de un antigeno.
IT8848117A0 (it) Molla per rubinetto
PT840746E (pt) Metodo para purificacao de proteinas
AU8919591A (en) Process for reactivating denatured protein
ES2165358T3 (es) Utilizaciones de la proteinquinasa de neurofilamento/tau pk40.
BR8107902A (pt) Processo para alterar quimicamente a especificidade do substrato de uma proteina,para produzir uma proteina semi-sintetica predeterminada e processo para produzir uma enzima semisintetica
FR2663816B1 (fr) Procede de traitement du colostrum par chromatographie d'adsorption sur hydroxyapatite, fraction active de colostrum obtenue et milieu cellulaire contenant ladite fraction active.
ATE76082T1 (de) Reinigungsmethode fuer antikoerper.
DK0618866T3 (da) Kort med informationsbærer og fremgangsmåde til dets fremstilling
IT8324286A0 (it) Attrezzo elastico di sospensione odi appoggio per tubazioni.
EP0466164A3 (en) Process for the preparation of 2-chloro-1,7-dihydropurin-6-one and process for the purification of the same
IT8121236A0 (it) Processo per la produzione di l-aminoacidi usando microorganismi immobilizzati.
FI883339A7 (fi) Menetelmä -2',3'-dideoksi-inosiinin valmistamiseksi entsymaattisella deaminoinnilla
NO177021C (no) Fremgangsmåte for å oppnå forbedret oljeutvinning under anvendelse av mikroorganismer
KR970009339B1 (en) Tpa from scolopendra subepinpes multilans and its purification method
PT92863A (pt) Purificacao num so passo de glicerol oxidase de origem microbiana
JPS53145982A (en) Purification of urokinase
KR940019857A (ko) 유로키나제의 정제 방법
UA19846A (uk) Спосіб очищеhhя ксаhтиhів

Legal Events

Date Code Title Description
EEIH Change in the person of patent owner
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee