ATE135402T1 - Reinigung von erwinia-l-asparaginase - Google Patents

Reinigung von erwinia-l-asparaginase

Info

Publication number
ATE135402T1
ATE135402T1 AT91913903T AT91913903T ATE135402T1 AT E135402 T1 ATE135402 T1 AT E135402T1 AT 91913903 T AT91913903 T AT 91913903T AT 91913903 T AT91913903 T AT 91913903T AT E135402 T1 ATE135402 T1 AT E135402T1
Authority
AT
Austria
Prior art keywords
asparaginase
pct
purification
sec
cation exchange
Prior art date
Application number
AT91913903T
Other languages
English (en)
Inventor
Christopher Roderick Goward
Original Assignee
Health Lab Service Board
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Health Lab Service Board filed Critical Health Lab Service Board
Application granted granted Critical
Publication of ATE135402T1 publication Critical patent/ATE135402T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
    • C12N9/82—Asparaginase (3.5.1.1)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/814—Enzyme separation or purification
    • Y10S435/815—Enzyme separation or purification by sorption
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/847—Erwinia

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Detergent Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT91913903T 1990-08-02 1991-08-01 Reinigung von erwinia-l-asparaginase ATE135402T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB909017002A GB9017002D0 (en) 1990-08-02 1990-08-02 Improved method for the purification of erwina l-asparaginase

Publications (1)

Publication Number Publication Date
ATE135402T1 true ATE135402T1 (de) 1996-03-15

Family

ID=10680081

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91913903T ATE135402T1 (de) 1990-08-02 1991-08-01 Reinigung von erwinia-l-asparaginase

Country Status (10)

Country Link
US (1) US5310670A (de)
EP (1) EP0541633B1 (de)
JP (1) JPH05508546A (de)
AT (1) ATE135402T1 (de)
AU (1) AU647819B2 (de)
CA (1) CA2075289A1 (de)
DE (1) DE69117956T2 (de)
DK (1) DK0541633T3 (de)
GB (1) GB9017002D0 (de)
WO (1) WO1992002616A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7396670B2 (en) 2002-10-11 2008-07-08 Novozymes A/S Asparaginases and method of preparing a heat-treated product
PT1571919E (pt) * 2002-12-19 2009-11-04 Dsm Ip Assets Bv Novo processo de produção de alimentos
BRPI0611901A2 (pt) 2005-06-14 2012-08-28 Amgen, Inc composição, liofilizado, kit, e, processo para preparar uma composição
US8420081B2 (en) * 2007-11-30 2013-04-16 Abbvie, Inc. Antibody formulations and methods of making same
US8883146B2 (en) 2007-11-30 2014-11-11 Abbvie Inc. Protein formulations and methods of making same
AU2013204044B2 (en) * 2007-11-30 2017-08-31 Abbvie Biotechnology Ltd. Protein formulations and methods of making same
WO2011003633A1 (en) * 2009-07-06 2011-01-13 Alize Pharma Ii Pegylated l-asparaginase
CN109640961B (zh) 2016-06-01 2021-11-02 施维雅知识产权英国有限公司 聚亚烷基氧化物-天冬酰胺酶制剂及其制备和使用方法
PT3528787T (pt) 2016-10-21 2026-03-11 Amgen Inc Formulações farmacêuticas e métodos para produzir as mesmas
SG11201912625QA (en) * 2017-06-21 2020-01-30 Jazz Pharmaceuticals Ireland Ltd Modified l-asparaginase
EP3701036A4 (de) 2017-10-27 2021-09-01 Pfenex Inc. Verfahren zur herstellung von rekombinantem e. coli
JP7784804B2 (ja) 2017-10-27 2025-12-12 フェネックス インク． 組み換えｅｒｗｉｎｉａアスパラギナーゼの製造のための方法
WO2022211829A1 (en) 2021-03-30 2022-10-06 Jazz Pharmaceuticals Ireland Ltd. Dosing of recombinant l-asparaginase

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1767389A1 (de) * 1968-05-06 1971-09-02 Bayer Ag Verfahren zur Abtrennung von Pyrogenen aus Rohpraeparaten von L-Asparaginase
DE1916723C3 (de) * 1968-04-05 1973-07-05 Kyowa Hakko Kogyo Kk Verfahren zur Reinigung von L-Asparaginase
US3597323A (en) * 1968-06-07 1971-08-03 Wadley Res Inst & Blood Bank Method of purifying l-asparaginase
US3637462A (en) * 1969-04-21 1972-01-25 Wadley Res Inst & Blood Bank Purification of enzymes
SU436085A1 (ru) * 1972-08-07 1974-07-15 В. М. Денисов, В. И. Максимов , Г. А. Молодова Способ очистки l-аспарагиназы
US4729957A (en) * 1984-12-13 1988-03-08 The United States Of America As Represented By The Department Of Health And Human Services Process for manufacture of L-asparaginase from erwinia chrysanthemi
JPS63502718A (ja) * 1985-12-13 1988-10-13 アメリカ合衆国 エルウィニア　カロトヴォラからのｌ−アスパラギナ−ゼの製造方法

Also Published As

Publication number Publication date
GB9017002D0 (en) 1990-09-19
CA2075289A1 (en) 1992-02-03
DE69117956D1 (de) 1996-04-18
AU647819B2 (en) 1994-03-31
US5310670A (en) 1994-05-10
EP0541633A1 (de) 1993-05-19
AU8280591A (en) 1992-03-02
JPH05508546A (ja) 1993-12-02
DE69117956T2 (de) 1996-07-25
DK0541633T3 (da) 1996-07-22
EP0541633B1 (de) 1996-03-13
WO1992002616A1 (en) 1992-02-20

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Legal Events

Date Code Title Description
EEIH Change in the person of patent owner
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee