ATE135574T1 - Verwendung von 2-cycloalkylamino-oxazolinen zur senkung oder stabilisierung des intraokulären druckes - Google Patents

Verwendung von 2-cycloalkylamino-oxazolinen zur senkung oder stabilisierung des intraokulären druckes

Info

Publication number: ATE135574T1
Authority: AT; Austria
Prior art keywords: intraocular pressure; oxazolines; cycloalkylamino; lowering; stabilizing
Prior art date: 1989-09-26

Application number

AT90310524T

Other languages

English (en)

Inventor

Charles Gluchowski

Original Assignee

Allergan Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-09-26

Filing date

1990-09-26

Publication date

1996-04-15

1990-09-26 Application filed by Allergan Inc filed Critical Allergan Inc

1996-04-15 Application granted granted Critical

1996-04-15 Publication of ATE135574T1 publication Critical patent/ATE135574T1/de

Links

230000004410 intraocular pressure Effects 0.000 title abstract 2
230000000087 stabilizing effect Effects 0.000 title 1
125000006273 (C1-C3) alkyl group Chemical group 0.000 abstract 1
208000010412 Glaucoma Diseases 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
125000001183 hydrocarbyl group Chemical group 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics

Landscapes

Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Ophthalmology & Optometry (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Medicinal Preparation (AREA)

AT90310524T 1989-09-26 1990-09-26 Verwendung von 2-cycloalkylamino-oxazolinen zur senkung oder stabilisierung des intraokulären druckes ATE135574T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US07/412,528 US5034406A (en)	1989-09-26	1989-09-26	Method for reducing or maintaining intraocular pressure

Publications (1)

Publication Number	Publication Date
ATE135574T1 true ATE135574T1 (de)	1996-04-15

Family

ID=23633363

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT90310524T ATE135574T1 (de)	1989-09-26	1990-09-26	Verwendung von 2-cycloalkylamino-oxazolinen zur senkung oder stabilisierung des intraokulären druckes

Country Status (6)

Country	Link
US (1)	US5034406A (de)
EP (1)	EP0420606B1 (de)
JP (1)	JP2997308B2 (de)
AT (1)	ATE135574T1 (de)
DE (1)	DE69026016T2 (de)
ES (1)	ES2084006T3 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5629345A (en) *	1993-07-23	1997-05-13	Vide Pharmaceuticals	Methods and compositions for ATP-sensitive K+ channel inhibition for lowering intraocular pressure
US5965620A (en) *	1993-07-23	1999-10-12	Vide Pharmaceuticals	Methods and compositions for ATP-sensitive K+ channel inhibition for lowering intraocular pressure
US6323204B1 (en)	1993-10-13	2001-11-27	Allergan	Methods for using (2-imidazolin-2-ylamino) quinoxaline derivatives
JP3683908B2 (ja) *	1993-10-13	2005-08-17	アラーガン、インコーポレイテッド	（２−イミダゾリン−２−イルアミノ）キノキサリン誘導体の使用方法
AUPP020297A0 (en) *	1997-11-05	1997-11-27	University Of Melbourne, The	A novel receptor, and compounds which bind thereto
US6841684B2 (en)	1997-12-04	2005-01-11	Allergan, Inc.	Imidiazoles having reduced side effects
US6329369B1 (en)	1997-12-04	2001-12-11	Allergan Sales, Inc.	Methods of treating pain and other conditions
CA2696314C (en) *	2007-08-15	2016-01-19	Allergan, Inc.	Therapeutic compounds

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE1670753A1 (de) *	1966-09-27	1970-07-16	Bayer Ag	Verfahren zur Herstellung von 2-Cycloalkylaminooxazolinen
US3676798A (en) *	1969-10-13	1972-07-11	Sperry Rand Corp	Cooling system for lasing media
FR2588189B1 (fr) *	1985-10-03	1988-12-02	Merck Sharp & Dohme	Composition pharmaceutique de type a transition de phase liquide-gel
GB8610909D0 (en) *	1986-05-03	1986-06-11	Beecham Group Plc	Compounds
CA1334168C (en) *	1988-04-26	1995-01-31	Louis M. De Santis	Antiglaucoma compositions containing combinations of .alpha.-2 agonists and .beta. blockers

1989
- 1989-09-26 US US07/412,528 patent/US5034406A/en not_active Expired - Lifetime
1990
- 1990-09-26 DE DE69026016T patent/DE69026016T2/de not_active Expired - Fee Related
- 1990-09-26 ES ES90310524T patent/ES2084006T3/es not_active Expired - Lifetime
- 1990-09-26 AT AT90310524T patent/ATE135574T1/de not_active IP Right Cessation
- 1990-09-26 EP EP90310524A patent/EP0420606B1/de not_active Expired - Lifetime
- 1990-09-26 JP JP2258753A patent/JP2997308B2/ja not_active Expired - Lifetime

Also Published As

Publication number	Publication date
ES2084006T3 (es)	1996-05-01
JPH03130224A (ja)	1991-06-04
US5034406A (en)	1991-07-23
EP0420606A3 (en)	1992-01-22
DE69026016D1 (de)	1996-04-25
EP0420606B1 (de)	1996-03-20
EP0420606A2 (de)	1991-04-03
JP2997308B2 (ja)	2000-01-11
DE69026016T2 (de)	1996-09-05

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Legal Events

Date	Code	Title	Description
1996-09-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties