ES2084006T3 - Uso de 2-cicloalquil-amino-oxazolinas para reducir o mantener la presion intraocular. - Google Patents

Uso de 2-cicloalquil-amino-oxazolinas para reducir o mantener la presion intraocular.

Info

Publication number
ES2084006T3
ES2084006T3 ES90310524T ES90310524T ES2084006T3 ES 2084006 T3 ES2084006 T3 ES 2084006T3 ES 90310524 T ES90310524 T ES 90310524T ES 90310524 T ES90310524 T ES 90310524T ES 2084006 T3 ES2084006 T3 ES 2084006T3
Authority
ES
Spain
Prior art keywords
intraocular pressure
cyclloalkyl
oxazolines
amino
reduce
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90310524T
Other languages
English (en)
Inventor
Charles Gluchowski
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Allergan Inc
Original Assignee
Allergan Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Allergan Inc filed Critical Allergan Inc
Application granted granted Critical
Publication of ES2084006T3 publication Critical patent/ES2084006T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Ophthalmology & Optometry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Medicinal Preparation (AREA)

Abstract

LA INVENCION EXPONE EL USO DE UN COMPONENTE DE FORMULA (I) Y SUS SALES Y MEZCLAS, EN LA QUE R1 ES UN ALQUILO C1-3; R2 ES UN HIDROGENO O UN ALQUILO C1-5, N ES DE 2 A 4, CADA X ES INDEPENDIENTEMENTE 1 O 2; EL ANILLO DE HIDROCARBUROS INCLUYE OPCIONALMENTE UN DOBLE ENLACE EN UNA POSICION DISTINTA DE LA ALFA-BETA. SE DESCRIBE TAMBIEN LA FABRICACION DE UN MEDICAMENTO PARA REDUCIR O MANTENER LA PRESION INTRAOCULAR EN EL OJO DE UN MAMIFERO, EJEMPLO, EN EL TRATAMIENTO DE UN GLAUCOMA.
ES90310524T 1989-09-26 1990-09-26 Uso de 2-cicloalquil-amino-oxazolinas para reducir o mantener la presion intraocular. Expired - Lifetime ES2084006T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/412,528 US5034406A (en) 1989-09-26 1989-09-26 Method for reducing or maintaining intraocular pressure

Publications (1)

Publication Number Publication Date
ES2084006T3 true ES2084006T3 (es) 1996-05-01

Family

ID=23633363

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90310524T Expired - Lifetime ES2084006T3 (es) 1989-09-26 1990-09-26 Uso de 2-cicloalquil-amino-oxazolinas para reducir o mantener la presion intraocular.

Country Status (6)

Country Link
US (1) US5034406A (es)
EP (1) EP0420606B1 (es)
JP (1) JP2997308B2 (es)
AT (1) ATE135574T1 (es)
DE (1) DE69026016T2 (es)
ES (1) ES2084006T3 (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5629345A (en) * 1993-07-23 1997-05-13 Vide Pharmaceuticals Methods and compositions for ATP-sensitive K+ channel inhibition for lowering intraocular pressure
US5965620A (en) * 1993-07-23 1999-10-12 Vide Pharmaceuticals Methods and compositions for ATP-sensitive K+ channel inhibition for lowering intraocular pressure
WO1995010280A1 (en) * 1993-10-13 1995-04-20 Allergan Methods for using (2-imidazolin-2-ylamino) quinoxaline derivatives
US6323204B1 (en) 1993-10-13 2001-11-27 Allergan Methods for using (2-imidazolin-2-ylamino) quinoxaline derivatives
AUPP020297A0 (en) * 1997-11-05 1997-11-27 University Of Melbourne, The A novel receptor, and compounds which bind thereto
US6329369B1 (en) 1997-12-04 2001-12-11 Allergan Sales, Inc. Methods of treating pain and other conditions
US6841684B2 (en) 1997-12-04 2005-01-11 Allergan, Inc. Imidiazoles having reduced side effects
BRPI0816157A2 (pt) * 2007-08-15 2017-06-13 Allergan Inc compostos adrenérgicos

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1670753A1 (de) * 1966-09-27 1970-07-16 Bayer Ag Verfahren zur Herstellung von 2-Cycloalkylaminooxazolinen
US3676798A (en) * 1969-10-13 1972-07-11 Sperry Rand Corp Cooling system for lasing media
FR2588189B1 (fr) * 1985-10-03 1988-12-02 Merck Sharp & Dohme Composition pharmaceutique de type a transition de phase liquide-gel
GB8610909D0 (en) * 1986-05-03 1986-06-11 Beecham Group Plc Compounds
CA1334168C (en) * 1988-04-26 1995-01-31 Louis M. De Santis Antiglaucoma compositions containing combinations of .alpha.-2 agonists and .beta. blockers

Also Published As

Publication number Publication date
JP2997308B2 (ja) 2000-01-11
JPH03130224A (ja) 1991-06-04
US5034406A (en) 1991-07-23
EP0420606B1 (en) 1996-03-20
DE69026016D1 (de) 1996-04-25
EP0420606A3 (en) 1992-01-22
EP0420606A2 (en) 1991-04-03
ATE135574T1 (de) 1996-04-15
DE69026016T2 (de) 1996-09-05

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