DK0426416T3 - Hidtil ukendte morpholinolforbindelser, deres fremstilling af anvendelse - Google Patents

Hidtil ukendte morpholinolforbindelser, deres fremstilling af anvendelse

Info

Publication number: DK0426416T3
Authority: DK; Denmark
Prior art keywords: compounds; morpholinol; preparation; new; carbon atoms
Prior art date: 1989-10-31

Application number

DK90311851.1T

Other languages

English (en)

Inventor

James Leroy Kelley

Barrett Randolph Cooper

David Lee Musso

Grady Evan Boswell

Original Assignee

Wellcome Found

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-10-31

Filing date

1990-10-30

Publication date

1994-03-14

1990-10-30 Application filed by Wellcome Found filed Critical Wellcome Found

1994-03-14 Application granted granted Critical

1994-03-14 Publication of DK0426416T3 publication Critical patent/DK0426416T3/da

Links

OURXRFYZEOUCRM-UHFFFAOYSA-N 4-hydroxymorpholine Chemical class ON1CCOCC1 OURXRFYZEOUCRM-UHFFFAOYSA-N 0.000 title abstract 2
125000004432 carbon atom Chemical group C* 0.000 abstract 3
125000000753 cycloalkyl group Chemical group 0.000 abstract 2
125000000217 alkyl group Chemical group 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
208000020016 psychiatric disease Diseases 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
- C07D265/30—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
- C07D265/32—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings with oxygen atoms directly attached to ring carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Psychiatry (AREA)
Veterinary Medicine (AREA)
Neurology (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Pain & Pain Management (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Medicinal Preparation (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

DK90311851.1T 1989-10-31 1990-10-30 Hidtil ukendte morpholinolforbindelser, deres fremstilling af anvendelse DK0426416T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB898924528A GB8924528D0 (en)	1989-10-31	1989-10-31	Heterocyclic pharmaceutical compounds,preparation and use

Publications (1)

Publication Number	Publication Date
DK0426416T3 true DK0426416T3 (da)	1994-03-14

Family

ID=10665482

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK90311851.1T DK0426416T3 (da)	1989-10-31	1990-10-30	Hidtil ukendte morpholinolforbindelser, deres fremstilling af anvendelse

Country Status (19)

Country	Link
US (1)	US5104870A (da)
EP (1)	EP0426416B1 (da)
JP (1)	JP2873076B2 (da)
AT (1)	ATE101604T1 (da)
AU (1)	AU645763B2 (da)
CA (1)	CA2028893C (da)
DE (1)	DE69006682T2 (da)
DK (1)	DK0426416T3 (da)
ES (1)	ES2062406T3 (da)
FI (1)	FI94753C (da)
GB (1)	GB8924528D0 (da)
HU (2)	HU207304B (da)
IE (1)	IE66115B1 (da)
LV (1)	LV11030B (da)
MX (1)	MX9203219A (da)
NZ (1)	NZ235882A (da)
PT (1)	PT95735B (da)
SG (1)	SG28347G (da)
ZA (1)	ZA908696B (da)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9108629D0 (en) *	1991-04-23	1991-06-12	Wellcome Found	Heterocyclic pharmaceutical compounds,preparation and use
AU1403899A (en) *	1997-11-14	1999-06-07	Glaxo Group Limited	Method of treating addiction to nicotine products
MA26693A1 (fr) *	1998-09-28	2004-12-20	Glaxo Group Ltd	Compositions pour administration par voie buccale
WO2001026641A2 (en) *	1999-10-13	2001-04-19	Glaxo Group Limited	Morpholinol derivatives for the treatment of obesity
EP2316468A1 (en)	2002-02-22	2011-05-04	Shire LLC	Delivery system and methods for protecting and administering dextroamphetamine
WO2007079470A2 (en) *	2006-01-03	2007-07-12	Algebra, Inc.	Therapeutic amine-arylsulfonamide conjugate compounds
JP5711724B2 (ja)	2009-04-15	2015-05-07	リサーチ・トライアングル・インスティチュート	モノアミン再取り込み阻害剤
AU2011255276B2 (en)	2010-05-21	2016-09-22	Research Triangle Institute	Phenylmorpholines and analogues thereof
ES2546492T3 (es) *	2010-05-21	2015-09-24	Research Triangle Institute	Derivados de 1-fenilmorfolina como análogos de hidroxibupropion para tratar drogodependencia
CN105949142B (zh) *	2016-05-21	2018-03-27	南华大学	具有抗抑郁活性的单一手性化合物及其制备方法和应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3117967A (en) *	1962-04-02	1964-01-14	Smith Kline French Lab	2-biphenylyl-2-hydroxy-morpholinium halides
FR2553413B1 (fr) *	1983-10-17	1986-03-21	Lafon Labor	Derives de 4-alkyl-2-hydroxy-3-methyl-2-phenyl-morpholine, procede de preparation et utilisation en therapeutique
GB8417170D0 (en) *	1984-07-05	1984-08-08	Wellcome Found	Heterocyclic pharmaceutical compounds

1989
- 1989-10-31 GB GB898924528A patent/GB8924528D0/en active Pending
1990
- 1990-10-30 HU HU906935A patent/HU207304B/hu not_active IP Right Cessation
- 1990-10-30 AT AT90311851T patent/ATE101604T1/de not_active IP Right Cessation
- 1990-10-30 ZA ZA908696A patent/ZA908696B/xx unknown
- 1990-10-30 SG SG1995904223A patent/SG28347G/en unknown
- 1990-10-30 ES ES90311851T patent/ES2062406T3/es not_active Expired - Lifetime
- 1990-10-30 PT PT95735A patent/PT95735B/pt not_active IP Right Cessation
- 1990-10-30 JP JP2293476A patent/JP2873076B2/ja not_active Expired - Fee Related
- 1990-10-30 EP EP90311851A patent/EP0426416B1/en not_active Expired - Lifetime
- 1990-10-30 NZ NZ235882A patent/NZ235882A/xx unknown
- 1990-10-30 CA CA002028893A patent/CA2028893C/en not_active Expired - Fee Related
- 1990-10-30 DK DK90311851.1T patent/DK0426416T3/da active
- 1990-10-30 IE IE388890A patent/IE66115B1/en not_active IP Right Cessation
- 1990-10-30 FI FI905356A patent/FI94753C/fi not_active IP Right Cessation
- 1990-10-30 DE DE69006682T patent/DE69006682T2/de not_active Expired - Fee Related
- 1990-10-30 AU AU65639/90A patent/AU645763B2/en not_active Ceased
1991
- 1991-04-02 US US07/680,637 patent/US5104870A/en not_active Expired - Lifetime
1992
- 1992-06-24 MX MX9203219A patent/MX9203219A/es unknown
1995
- 1995-02-09 LV LVP-95-27A patent/LV11030B/en unknown
- 1995-05-09 HU HU95P/P00125P patent/HU211304A9/hu unknown

Also Published As

Publication number	Publication date
HU906935D0 (en)	1991-05-28
PT95735A (pt)	1991-09-13
FI94753B (fi)	1995-07-14
LV11030A (lv)	1996-02-20
JPH03206084A (ja)	1991-09-09
ATE101604T1 (de)	1994-03-15
ES2062406T3 (es)	1994-12-16
ZA908696B (en)	1992-07-29
IE903888A1 (en)	1991-05-08
EP0426416B1 (en)	1994-02-16
FI94753C (fi)	1995-10-25
PT95735B (pt)	1998-01-30
FI905356A0 (fi)	1990-10-30
HUT57748A (en)	1991-12-30
GB8924528D0 (en)	1989-12-20
AU645763B2 (en)	1994-01-27
HU207304B (en)	1993-03-29
JP2873076B2 (ja)	1999-03-24
SG28347G (en)	1995-09-18
DE69006682T2 (de)	1994-08-04
HU211304A9 (en)	1995-11-28
DE69006682D1 (de)	1994-03-24
EP0426416A1 (en)	1991-05-08
IE66115B1 (en)	1995-12-13
CA2028893C (en)	2000-10-10
MX9203219A (es)	1992-07-01
CA2028893A1 (en)	1991-05-01
LV11030B (en)	1996-08-20
US5104870A (en)	1992-04-14
NZ235882A (en)	1993-05-26
AU6563990A (en)	1991-05-09

Publication	Publication Date	Title
ATE85608T1 (de)	1993-02-15	Verbindungen mit biologischer aktivitaet.
ES2071681T3 (es)	1995-07-01	Compuestos macrociclicos.
DK0756595T3 (da)	2002-06-17	Substituerede 1,3-oxathiolaner med antivirale egenskaber
ATE157975T1 (de)	1997-09-15	Oxazolidinedione-derivate, ihre herstellung und ihre verwendung zur hemmung zucker und lipid in blut
DE68914292D1 (de)	1994-05-11	Zusammensetzung zur Behandlung von ischämischen Störungen in Organen.
DK0426416T3 (da)	1994-03-14	Hidtil ukendte morpholinolforbindelser, deres fremstilling af anvendelse
AU2868689A (en)	1989-07-27	Use of 1,4-disubstituted-piperidinyl compounds in the manufacture of a medicament for the treatment of insomnia
ATE110721T1 (de)	1994-09-15	2-alkyl-3-benzoylbenzofurane und diese enthaltende pharmazeutische zusammensetzungen.
ATE141605T1 (de)	1996-09-15	Thienotriazoldiazepinverbindungen und deren pharmazeutische anwendungen
KR880007070A (ko)	1988-08-26	백내장 치료용 약학 조성물
DE3752272D1 (de)	1999-05-27	Verwendung eines Thioesters zur Herstellung von pharmazeutischen Zusammensetzungen zur Behandlung von Ischämie und von Reperfusion-Syndromen
RU94042230A (ru)	1996-11-20	Производные 1,3,4-оксадиазол-2-(3н)-она, их приготовление и применение в терапии
DE3864209D1 (de)	1991-09-19	Pharmazeutische verwendung aromatischer thioaether.