ATE138374T1 - Benzo(b)thiophen-2-carboxamide zur behandlung von krankheiten des zentralnervensystems - Google Patents

Benzo(b)thiophen-2-carboxamide zur behandlung von krankheiten des zentralnervensystems

Info

Publication number: ATE138374T1
Authority: AT; Austria
Prior art keywords: optionally substituted; treatment; nervous system; central nervous; thiophen
Prior art date: 1991-11-18

Application number

AT92310406T

Other languages

English (en)

Inventor

John Fairhurst

David Edward Tupper

Original Assignee

Lilly Industries Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-11-18

Filing date

1992-11-13

Publication date

1996-06-15

1991-11-18 Priority claimed from GB919124439A external-priority patent/GB9124439D0/en

1992-08-26 Priority claimed from GB929218112A external-priority patent/GB9218112D0/en

1992-11-13 Application filed by Lilly Industries Ltd filed Critical Lilly Industries Ltd

1996-06-15 Application granted granted Critical

1996-06-15 Publication of ATE138374T1 publication Critical patent/ATE138374T1/de

Links

GYSCBCSGKXNZRH-UHFFFAOYSA-N 1-benzothiophene-2-carboxamide Chemical compound C1=CC=C2SC(C(=O)N)=CC2=C1 GYSCBCSGKXNZRH-UHFFFAOYSA-N 0.000 title 1
208000015114 central nervous system disease Diseases 0.000 title 1
125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 5
125000000753 cycloalkyl group Chemical group 0.000 abstract 3
150000002431 hydrogen Chemical class 0.000 abstract 3
229910052739 hydrogen Inorganic materials 0.000 abstract 3
239000001257 hydrogen Substances 0.000 abstract 3
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 3
150000001875 compounds Chemical class 0.000 abstract 2
125000000229 (C1-C4)alkoxy group Chemical group 0.000 abstract 1
125000006656 (C2-C4) alkenyl group Chemical group 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
210000003169 central nervous system Anatomy 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
208000035475 disorder Diseases 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
150000002367 halogens Chemical class 0.000 abstract 1
125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
125000005544 phthalimido group Chemical group 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
125000001712 tetrahydronaphthyl group Chemical group C1(CCCC2=CC=CC=C12)* 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D333/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D333/70—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 2
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Compounds Containing Sulfur Atoms (AREA)

AT92310406T 1991-11-18 1992-11-13 Benzo(b)thiophen-2-carboxamide zur behandlung von krankheiten des zentralnervensystems ATE138374T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB919124439A GB9124439D0 (en)	1991-11-18	1991-11-18	Pharmaceutical compounds
GB929218112A GB9218112D0 (en)	1992-08-26	1992-08-26	Pharmaceutical compounds

Publications (1)

Publication Number	Publication Date
ATE138374T1 true ATE138374T1 (de)	1996-06-15

Family

ID=26299883

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT92310406T ATE138374T1 (de)	1991-11-18	1992-11-13	Benzo(b)thiophen-2-carboxamide zur behandlung von krankheiten des zentralnervensystems

Country Status (9)

Country	Link
US (1)	US5338735A (de)
EP (1)	EP0543584B1 (de)
JP (1)	JPH05194485A (de)
AT (1)	ATE138374T1 (de)
CA (1)	CA2082839A1 (de)
DE (1)	DE69210959T2 (de)
DK (1)	DK0543584T3 (de)
ES (1)	ES2087463T3 (de)
GR (1)	GR3020488T3 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5370685A (en) *	1991-07-16	1994-12-06	Stanford Surgical Technologies, Inc.	Endovascular aortic valve replacement
FR2793793B1 (fr) *	1999-05-19	2004-02-27	Adir	Nouveaux derives dimeriques substitues, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
US7649023B2 (en) *	2002-06-11	2010-01-19	Novartis Ag	Biodegradable block copolymeric compositions for drug delivery
US7674822B2 (en)	2004-11-24	2010-03-09	Wyeth	PTP1b inhibitors
TW201212918A (en) *	2010-08-23	2012-04-01	Lundbeck & Co As H	Therapeutic uses of 1-[2-(2,4-dimethyl-phenylsulfanyl)phenyl]piperazine

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NL133069C (de) *	1966-07-29
MC807A1 (fr) *	1968-07-29	1970-07-30	Soc Et Scient Et Ind De L Ile	Procédé de préparation de 3-alcoxy-thianaphtene-carboxamide substituées ou non
US3838169A (en) *	1968-07-29	1974-09-24	Ile De France	3-alkoxy-thianaphthene-2-carboxamides
IL74694A0 (en) *	1984-04-02	1985-06-30	Merck & Co Inc	N-alkenyl-3-hydroxybenzo(b)thiophene-2-carboxamide derivatives,their preparation and pharmaceutical compositions containing them
US4782080A (en) *	1985-09-16	1988-11-01	Merck & Co., Inc.	N-alkenyl-2-hydroxybenzo(b)thiophene-3-carboxamide derivatives as dual cyclooxygenase and lipoxygenase inhibitors
US4800211A (en) *	1986-08-18	1989-01-24	Merck & Co., Inc.	5-methylthio-3-hydroxybenzo [b]thiophene-2-carboxamide derivatives as cyclooxygenase and lipoxygenase inhibitors
EP0403885A1 (de) *	1989-06-20	1990-12-27	Bayer Ag	Verwendung von 3-Hydroxybenzothiophenen zur Bekämpfung von Endoparasiten, neue 3-Hydroxybenzothiophene und Verfahren zu ihrer Herstellung
US5096908A (en) *	1990-05-04	1992-03-17	Eli Lilly And Company	Method of inhibiting gastric acid secretion

1992
- 1992-11-13 DK DK92310406.1T patent/DK0543584T3/da active
- 1992-11-13 DE DE69210959T patent/DE69210959T2/de not_active Expired - Fee Related
- 1992-11-13 ES ES92310406T patent/ES2087463T3/es not_active Expired - Lifetime
- 1992-11-13 AT AT92310406T patent/ATE138374T1/de active
- 1992-11-13 CA CA002082839A patent/CA2082839A1/en not_active Abandoned
- 1992-11-13 EP EP92310406A patent/EP0543584B1/de not_active Expired - Lifetime
- 1992-11-17 JP JP4305768A patent/JPH05194485A/ja active Pending
1993
- 1993-08-12 US US08/104,272 patent/US5338735A/en not_active Expired - Fee Related
1996
- 1996-07-09 GR GR960401856T patent/GR3020488T3/el unknown

Also Published As

Publication number	Publication date
JPH05194485A (ja)	1993-08-03
EP0543584A1 (de)	1993-05-26
ES2087463T3 (es)	1996-07-16
DE69210959D1 (de)	1996-06-27
DK0543584T3 (da)	1996-07-01
US5338735A (en)	1994-08-16
GR3020488T3 (en)	1996-10-31
EP0543584B1 (de)	1996-05-22
DE69210959T2 (de)	1996-09-26
CA2082839A1 (en)	1993-05-19

Publication	Publication Date	Title
DE69021679D1 (de)	1995-09-21	Verwendung von Bis(3,4-Dialkylbenzyliden)sorbitolacetale und diese enthaltende Zusammensetzungen.
DE3781716D1 (de)	1992-10-22	Mittel zur ortsspezifischen alkylierung.
DE68914292D1 (de)	1994-05-11	Zusammensetzung zur Behandlung von ischämischen Störungen in Organen.
MX9202844A (es)	1992-06-30	1-indolilalquil-4-( alcoxi-pirimidinil) piperazinas y composicion farmaceutica que las contiene.
DE3771039D1 (de)	1991-08-01	Therapeutisches mittel.
FI885128A0 (fi)	1988-11-07	Foerfarande foer framstaellning av nya terapeutiskt anvaendbara kinolinkarboxylsyraderivat.
ATE93232T1 (de)	1993-09-15	Bis(methylendioxy)biphenyl-verbindungen.
ES8702403A1 (es)	1987-01-01	Un procedimiento para la preparacion de nuevas n-((4-piperidinil)alquil)oxazol y tiazolaminas condensadas biciclicas sustituidas
SE8605504D0 (sv)	1986-12-19	Novel chroman derivatives
DK26289A (da)	1989-07-22	Anvendelse af 1,4-disubstitueret piperidinyl til fremstilling af et farmaceutisk praeparat til behandling af insomnia
ATE79257T1 (de)	1992-08-15	Verwendung von tetrahydrobenz(c,d>indol-6carboxamiden zur herstellung von arzneimitteln zur behandlung von angstzustaenden.
ATE138374T1 (de)	1996-06-15	Benzo(b)thiophen-2-carboxamide zur behandlung von krankheiten des zentralnervensystems
DE69005984D1 (de)	1994-02-24	2-Hydroxy-3-phenoxypropylaminoverbindungen.
DK663588D0 (da)	1988-11-28	Hidtil ukendte forbindelser
DE3882571D1 (de)	1993-09-02	Sulfonyldecahydro-8h-isochino(2,1-g)(1,6)naphthyridine, optische isomere davon und verwandte verbindungen.
ATE52499T1 (de)	1990-05-15	5-alkylsulfonylsalicylanilide und mikrobizide zusammensetzungen fuer die regulierung des wachstums von mikroorganismen.
GR3019583T3 (de)	1996-07-31
ATE73759T1 (de)	1992-04-15	Fungizide.
ES2031594T3 (es)	1992-12-16	Tioeteres aromaticos.
ATE151987T1 (de)	1997-05-15	Verwendung von 3-pyridazinone zur verringerung der blutplätchenzahl
ATE186912T1 (de)	1999-12-15	Carbamoylpyrrolidon-derivate zur behandlung von depressionen und cerebrovasculären störungen
DE3782229D1 (de)	1992-11-19	Verwendung von 2-oxo-imidazolidin-derivaten zur behandlung von nierenkrankheiten.