ES2087463T3 - Benzo(b)tiofen-2-carboxamidas para el tratamiento de trastornos del sistema nervioso central. - Google Patents
Benzo(b)tiofen-2-carboxamidas para el tratamiento de trastornos del sistema nervioso central.Info
- Publication number
- ES2087463T3 ES2087463T3 ES92310406T ES92310406T ES2087463T3 ES 2087463 T3 ES2087463 T3 ES 2087463T3 ES 92310406 T ES92310406 T ES 92310406T ES 92310406 T ES92310406 T ES 92310406T ES 2087463 T3 ES2087463 T3 ES 2087463T3
- Authority
- ES
- Spain
- Prior art keywords
- treatment
- nervous system
- central nervous
- rent
- thiofen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 208000015114 central nervous system disease Diseases 0.000 title 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical group [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- RZVAJINKPMORJF-UHFFFAOYSA-N Acetaminophen Chemical compound CC(=O)NC1=CC=C(O)C=C1 RZVAJINKPMORJF-UHFFFAOYSA-N 0.000 abstract 1
- JCXJVPUVTGWSNB-UHFFFAOYSA-N Nitrogen dioxide Chemical class O=[N]=O JCXJVPUVTGWSNB-UHFFFAOYSA-N 0.000 abstract 1
- CIUQDSCDWFSTQR-UHFFFAOYSA-N [C]1=CC=CC=C1 Chemical group [C]1=CC=CC=C1 CIUQDSCDWFSTQR-UHFFFAOYSA-N 0.000 abstract 1
- 210000003169 central nervous system Anatomy 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D333/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D333/70—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB919124439A GB9124439D0 (en) | 1991-11-18 | 1991-11-18 | Pharmaceutical compounds |
| GB929218112A GB9218112D0 (en) | 1992-08-26 | 1992-08-26 | Pharmaceutical compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2087463T3 true ES2087463T3 (es) | 1996-07-16 |
Family
ID=26299883
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES92310406T Expired - Lifetime ES2087463T3 (es) | 1991-11-18 | 1992-11-13 | Benzo(b)tiofen-2-carboxamidas para el tratamiento de trastornos del sistema nervioso central. |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US5338735A (de) |
| EP (1) | EP0543584B1 (de) |
| JP (1) | JPH05194485A (de) |
| AT (1) | ATE138374T1 (de) |
| CA (1) | CA2082839A1 (de) |
| DE (1) | DE69210959T2 (de) |
| DK (1) | DK0543584T3 (de) |
| ES (1) | ES2087463T3 (de) |
| GR (1) | GR3020488T3 (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5370685A (en) * | 1991-07-16 | 1994-12-06 | Stanford Surgical Technologies, Inc. | Endovascular aortic valve replacement |
| FR2793793B1 (fr) * | 1999-05-19 | 2004-02-27 | Adir | Nouveaux derives dimeriques substitues, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| US7649023B2 (en) * | 2002-06-11 | 2010-01-19 | Novartis Ag | Biodegradable block copolymeric compositions for drug delivery |
| US7674822B2 (en) | 2004-11-24 | 2010-03-09 | Wyeth | PTP1b inhibitors |
| TW201212918A (en) * | 2010-08-23 | 2012-04-01 | Lundbeck & Co As H | Therapeutic uses of 1-[2-(2,4-dimethyl-phenylsulfanyl)phenyl]piperazine |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL133069C (de) * | 1966-07-29 | |||
| MC807A1 (fr) * | 1968-07-29 | 1970-07-30 | Soc Et Scient Et Ind De L Ile | Procédé de préparation de 3-alcoxy-thianaphtene-carboxamide substituées ou non |
| US3838169A (en) * | 1968-07-29 | 1974-09-24 | Ile De France | 3-alkoxy-thianaphthene-2-carboxamides |
| IL74694A0 (en) * | 1984-04-02 | 1985-06-30 | Merck & Co Inc | N-alkenyl-3-hydroxybenzo(b)thiophene-2-carboxamide derivatives,their preparation and pharmaceutical compositions containing them |
| US4782080A (en) * | 1985-09-16 | 1988-11-01 | Merck & Co., Inc. | N-alkenyl-2-hydroxybenzo(b)thiophene-3-carboxamide derivatives as dual cyclooxygenase and lipoxygenase inhibitors |
| US4800211A (en) * | 1986-08-18 | 1989-01-24 | Merck & Co., Inc. | 5-methylthio-3-hydroxybenzo [b]thiophene-2-carboxamide derivatives as cyclooxygenase and lipoxygenase inhibitors |
| EP0403885A1 (de) * | 1989-06-20 | 1990-12-27 | Bayer Ag | Verwendung von 3-Hydroxybenzothiophenen zur Bekämpfung von Endoparasiten, neue 3-Hydroxybenzothiophene und Verfahren zu ihrer Herstellung |
| US5096908A (en) * | 1990-05-04 | 1992-03-17 | Eli Lilly And Company | Method of inhibiting gastric acid secretion |
-
1992
- 1992-11-13 DK DK92310406.1T patent/DK0543584T3/da active
- 1992-11-13 DE DE69210959T patent/DE69210959T2/de not_active Expired - Fee Related
- 1992-11-13 ES ES92310406T patent/ES2087463T3/es not_active Expired - Lifetime
- 1992-11-13 AT AT92310406T patent/ATE138374T1/de active
- 1992-11-13 CA CA002082839A patent/CA2082839A1/en not_active Abandoned
- 1992-11-13 EP EP92310406A patent/EP0543584B1/de not_active Expired - Lifetime
- 1992-11-17 JP JP4305768A patent/JPH05194485A/ja active Pending
-
1993
- 1993-08-12 US US08/104,272 patent/US5338735A/en not_active Expired - Fee Related
-
1996
- 1996-07-09 GR GR960401856T patent/GR3020488T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JPH05194485A (ja) | 1993-08-03 |
| EP0543584A1 (de) | 1993-05-26 |
| DE69210959D1 (de) | 1996-06-27 |
| DK0543584T3 (da) | 1996-07-01 |
| US5338735A (en) | 1994-08-16 |
| GR3020488T3 (en) | 1996-10-31 |
| EP0543584B1 (de) | 1996-05-22 |
| ATE138374T1 (de) | 1996-06-15 |
| DE69210959T2 (de) | 1996-09-26 |
| CA2082839A1 (en) | 1993-05-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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