ATE138690T1 - Verfahren zur enzymatischen herstellung von beta- lactamen - Google Patents

Verfahren zur enzymatischen herstellung von beta- lactamen

Info

Publication number: ATE138690T1
Authority: AT; Austria
Prior art keywords: beta; lactamen; enzymatic production; enzymatic; aminophenylacetamido
Prior art date: 1988-04-26

Application number

AT89201074T

Other languages

English (en)

Inventor

Der Laken Cornelis Jacobus Van

Original Assignee

Gist Brocades Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-04-26

Filing date

1989-04-25

Publication date

1996-06-15

1989-04-25 Application filed by Gist Brocades Nv filed Critical Gist Brocades Nv

1996-06-15 Application granted granted Critical

1996-06-15 Publication of ATE138690T1 publication Critical patent/ATE138690T1/de

Links

230000002255 enzymatic effect Effects 0.000 title 1
ZGUNAGUHMKGQNY-UHFFFAOYSA-N alpha-phenylglycine Chemical class OC(=O)C(N)C1=CC=CC=C1 ZGUNAGUHMKGQNY-UHFFFAOYSA-N 0.000 abstract 1
238000006911 enzymatic reaction Methods 0.000 abstract 1
150000003952 β-lactams Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P37/00—Preparation of compounds having a 4-thia-1-azabicyclo [3.2.0] heptane ring system, e.g. penicillin
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P37/00—Preparation of compounds having a 4-thia-1-azabicyclo [3.2.0] heptane ring system, e.g. penicillin
- C12P37/04—Preparation of compounds having a 4-thia-1-azabicyclo [3.2.0] heptane ring system, e.g. penicillin by acylation of the substituent in the 6 position

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Zoology (AREA)
Life Sciences & Earth Sciences (AREA)
Wood Science & Technology (AREA)
Chemical Kinetics & Catalysis (AREA)
Microbiology (AREA)
General Chemical & Material Sciences (AREA)
Biotechnology (AREA)
Health & Medical Sciences (AREA)
Biochemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
General Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Pyrrole Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

AT89201074T 1988-04-26 1989-04-25 Verfahren zur enzymatischen herstellung von beta- lactamen ATE138690T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP88200811		1988-04-26

Publications (1)

Publication Number	Publication Date
ATE138690T1 true ATE138690T1 (de)	1996-06-15

Family

ID=8199787

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT89201074T ATE138690T1 (de)	1988-04-26	1989-04-25	Verfahren zur enzymatischen herstellung von beta- lactamen

Country Status (9)

Country	Link
EP (1)	EP0339751B1 (de)
JP (1)	JP2771244B2 (de)
KR (1)	KR890016184A (de)
AT (1)	ATE138690T1 (de)
DE (1)	DE68926548T2 (de)
DK (1)	DK198789A (de)
ES (1)	ES2090031T3 (de)
GR (1)	GR3020486T3 (de)
PT (1)	PT90373B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0537255B1 (de) *	1990-07-04	2006-02-15	DSM IP Assets B.V.	Verfahren zur herstellung von beta-lactamen
AU3345193A (en) *	1991-12-19	1993-07-19	Novo Nordisk A/S	An improved method for the preparation of certain beta-lactam antibiotics
WO1995034675A1 (en) *	1994-06-10	1995-12-21	Gist-Brocades B.V.	Improved acylation method for penicillins and cephalosporins
ES2139923T3 (es) *	1994-07-18	2000-02-16	Dsm Nv	Procedimiento para preparar beta-lactamas a concentraciones de reaccionantes constantemente altas.
WO1998000382A1 (en)	1996-07-02	1998-01-08	Toray Industries, Inc.	Processes for the preparation of optically active ketones
EP0918879A1 (de) *	1997-04-22	1999-06-02	Gist-Brocades B.V.	METHODE ZUR HERSTELLUNG VON -g(b)-LACTAM ANTIBIOTIKUM
EP2614066B1 (de)	2010-09-07	2017-11-29	DSM Sinochem Pharmaceuticals Netherlands B.V.	Verfahren zur herstellung von cephalosporinen
EP2723882B1 (de)	2011-06-23	2019-05-01	Centrient Pharmaceuticals Netherlands B.V.	Verfahren zur herstellung von 3 '-thiosubstituierten cephalosporinen unter verwendung einer penicillin-g-acylase
WO2012175587A2 (en)	2011-06-23	2012-12-27	Dsm Sinochem Pharmaceuticals Netherlands B.V.	Novel crystalline cefoperazone intermediate

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS5343597B1 (de) *	1970-12-25	1978-11-21
JPS5548797B1 (de) *	1971-04-02	1980-12-08
US3904606A (en) *	1973-01-12	1975-09-09	Upjohn Co	Process for preparing optically active 6-(' -amino-acetamido)penicillanic acids and 7-(' -aminoacetamido) cephalosporanic acids
JPS51133488A (en) *	1975-05-14	1976-11-19	Shionogi & Co Ltd	Process for producing antibiotics enzymatically
JPS591995Y2 (ja) *	1980-02-21	1984-01-19	日立造船株式会社	微細粒を含有する液体の貯溜槽
JPS63294932A (ja) *	1987-05-27	1988-12-01	Niigata Eng Co Ltd	スラリーの貯蔵装置
JPS63294933A (ja) *	1987-05-27	1988-12-01	Niigata Eng Co Ltd	スラリ−貯槽

1989
- 1989-04-25 AT AT89201074T patent/ATE138690T1/de not_active IP Right Cessation
- 1989-04-25 ES ES89201074T patent/ES2090031T3/es not_active Expired - Lifetime
- 1989-04-25 DE DE68926548T patent/DE68926548T2/de not_active Expired - Fee Related
- 1989-04-25 DK DK198789A patent/DK198789A/da not_active Application Discontinuation
- 1989-04-25 EP EP89201074A patent/EP0339751B1/de not_active Expired - Lifetime
- 1989-04-26 PT PT90373A patent/PT90373B/pt not_active IP Right Cessation
- 1989-04-26 KR KR1019890005508A patent/KR890016184A/ko not_active Withdrawn
- 1989-04-26 JP JP1107111A patent/JP2771244B2/ja not_active Expired - Fee Related
1996
- 1996-07-09 GR GR960401854T patent/GR3020486T3/el unknown

Also Published As

Publication number	Publication date
EP0339751B1 (de)	1996-05-29
DE68926548T2 (de)	1996-09-26
GR3020486T3 (en)	1996-10-31
JP2771244B2 (ja)	1998-07-02
KR890016184A (ko)	1989-11-28
DK198789A (da)	1989-10-27
DK198789D0 (da)	1989-04-25
PT90373A (pt)	1989-11-10
EP0339751A1 (de)	1989-11-02
JPH01312998A (ja)	1989-12-18
DE68926548D1 (de)	1996-07-04
PT90373B (pt)	1994-09-30
ES2090031T3 (es)	1996-10-16

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Legal Events

Date	Code	Title	Description
2004-05-15	EEIH	Change in the person of patent owner
2006-01-15	REN	Ceased due to non-payment of the annual fee